Activation of AMP-activated protein kinase α2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo

Nature Medicine

Volumn 18, Issue 6, 2012, Pages 902-910

  Wang, Shuangxi ^a,b   Zhang, Cheng ^a,b   Zhang, Miao ^a   Liang, Bin ^a   Zhu, Huaiping ^a   Lee, Jiyeon ^a   Viollet, Benoit ^c   Xia, Lijun ^d   Zhang, Yun ^b   Zou, Ming Hui ^a,b  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b SHANDONG UNIVERSITY   (China)

^c INSTITUT COCHIN   (France)

^d OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMP ACTIVATED PROTEIN KINASE ALPHA1; AMP ACTIVATED PROTEIN KINASE ALPHA2; ANGIOTENSIN II; APOLIPOPROTEIN E; CIGARETTE SMOKE; GELATINASE A; GELATINASE B; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HISTONE H2AX; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LACTATE DEHYDROGENASE; MESSENGER RNA; NICOTINE; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR AP 2ALPHA; UNCLASSIFIED DRUG;

ABDOMINAL AORTA ANEURYSM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME SUBUNIT; GENE DELETION; GENE EXPRESSION; IN VIVO STUDY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RISK FACTOR; SMOKING; VASCULAR SMOOTH MUSCLE;

AMP-ACTIVATED PROTEIN KINASES; ANGIOTENSIN II; ANIMALS; AORTIC ANEURYSM, ABDOMINAL; CELLS, CULTURED; HUMANS; MATRIX METALLOPROTEINASE 2; MICE; MICE, INBRED C57BL; MUSCLE, SMOOTH, VASCULAR; NICOTINE; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; SMOKING; TRANSCRIPTION FACTOR AP-2;

MUS;

EID: 84862007631     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2711     Document Type: Article

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