-
1
-
-
33646450620
-
Physiology of the blood–brain barrier and its consequences for drug transport to the brain
-
COI: 1:CAS:528:DC%2BD1cXhvVOhtb4%3D
-
Abbott NJ. Physiology of the blood–brain barrier and its consequences for drug transport to the brain. Int Congr Ser. 2005;1277:3–18.
-
(2005)
Int Congr Ser
, vol.1277
, pp. 3-18
-
-
Abbott, N.J.1
-
2
-
-
34547642139
-
Blood–brain barrier transport of therapeutics via receptor mediation
-
COI: 1:CAS:528:DC%2BD2sXosVKgt74%3D, PID: 17619996
-
Jones AR, Shusta EV. Blood–brain barrier transport of therapeutics via receptor mediation. Pharm Res. 2007;24:1759–71.
-
(2007)
Pharm Res
, vol.24
, pp. 1759-1771
-
-
Jones, A.R.1
Shusta, E.V.2
-
3
-
-
2342471420
-
The blood–brain barrier: an overview: structure, regulation, and clinical implications
-
COI: 1:CAS:528:DC%2BD2cXjs1altL8%3D, PID: 15207256
-
Ballabh P, Braun A, Nedergaard M. The blood–brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol Dis. 2004;16(1):1–13.
-
(2004)
Neurobiol Dis
, vol.16
, Issue.1
, pp. 1-13
-
-
Ballabh, P.1
Braun, A.2
Nedergaard, M.3
-
4
-
-
77956344034
-
Looking at the blood–brain barrier: molecular anatomy and possible investigation approaches
-
COI: 1:CAS:528:DC%2BC3cXhtFWqtLnJ, PID: 20685221
-
Cardoso FL, Brites D, Brito MA. Looking at the blood–brain barrier: molecular anatomy and possible investigation approaches. Brain Res Rev. 2010;64:328–63.
-
(2010)
Brain Res Rev
, vol.64
, pp. 328-363
-
-
Cardoso, F.L.1
Brites, D.2
Brito, M.A.3
-
5
-
-
0042899083
-
Blood–brain barrier drug targeting: the future of brain drug development
-
COI: 1:CAS:528:DC%2BD3sXjsVWhsrk%3D, PID: 14993430
-
Pardridge WM. Blood–brain barrier drug targeting: the future of brain drug development. Mol Interv. 2003;3:90–105.
-
(2003)
Mol Interv
, vol.3
, pp. 90-105
-
-
Pardridge, W.M.1
-
6
-
-
65749100582
-
Drug interactions at the blood–brain barrier: fact or fantasy?
-
COI: 1:CAS:528:DC%2BD1MXms1ahsb0%3D, PID: 19393264
-
Eyal S, Hsiao P, Unadkat JD. Drug interactions at the blood–brain barrier: fact or fantasy? Pharmacol Ther. 2009;123:80–104.
-
(2009)
Pharmacol Ther
, vol.123
, pp. 80-104
-
-
Eyal, S.1
Hsiao, P.2
Unadkat, J.D.3
-
7
-
-
84893287460
-
Transport of nanoparticles through the blood–brain barrier for imaging and therapeutic applications
-
COI: 1:CAS:528:DC%2BC2cXhsFakurg%3D, PID: 24362586
-
Shilo M, Motiei M, Hana P, Popovtzer R. Transport of nanoparticles through the blood–brain barrier for imaging and therapeutic applications. Nanoscale. 2014;6(4):2146–52.
-
(2014)
Nanoscale
, vol.6
, Issue.4
, pp. 2146-2152
-
-
Shilo, M.1
Motiei, M.2
Hana, P.3
Popovtzer, R.4
-
8
-
-
22944483792
-
The blood–brain barrier/neurovascular unit in health and disease
-
COI: 1:CAS:528:DC%2BD2MXlsFejtL0%3D, PID: 15914466
-
Hawkins BT, Davis TP. The blood–brain barrier/neurovascular unit in health and disease. Pharmacol Rev. 2005;57:173–85.
-
(2005)
Pharmacol Rev
, vol.57
, pp. 173-185
-
-
Hawkins, B.T.1
Davis, T.P.2
-
9
-
-
48049091363
-
Mechanisms of lumbrokinase in protection of cerebral ischemia
-
COI: 1:CAS:528:DC%2BD1cXpt1KntLw%3D, PID: 18597751
-
Ji H, Wang L, Bi H, Sun L, Cai B, Wang Y, et al. Mechanisms of lumbrokinase in protection of cerebral ischemia. Eur J Pharmacol. 2008;590:281–9.
-
(2008)
Eur J Pharmacol
, vol.590
, pp. 281-289
-
-
Ji, H.1
Wang, L.2
Bi, H.3
Sun, L.4
Cai, B.5
Wang, Y.6
-
10
-
-
0036362078
-
The role of recombinant pro-urokinase (r-pro-UK) and intraarterial thrombolysis in acute ischemic stroke: the PROACT trials. Prolyse in acute cerebral thromboembolism
-
Furlan AJ, Abou-Chebi A. The role of recombinant pro-urokinase (r-pro-UK) and intraarterial thrombolysis in acute ischemic stroke: the PROACT trials. Prolyse in acute cerebral thromboembolism. Curr Med Res Opin. 2002;18 Suppl 2:44–7.
-
(2002)
Curr Med Res Opin
, vol.18
, pp. 44-47
-
-
Furlan, A.J.1
Abou-Chebi, A.2
-
11
-
-
18444386848
-
Molecular mechanisms of fibrinolysis
-
COI: 1:CAS:528:DC%2BD2MXltlWnt7c%3D, PID: 15842654
-
Cesarman-Maus G, Hajjar KA. Molecular mechanisms of fibrinolysis. Br J Haematol. 2005;129(3):307–21.
-
(2005)
Br J Haematol
, vol.129
, Issue.3
, pp. 307-321
-
-
Cesarman-Maus, G.1
Hajjar, K.A.2
-
12
-
-
31944447012
-
Structure of human urokinase plasminogen activator in complex with its receptor
-
COI: 1:CAS:528:DC%2BD28XptVyltA%3D%3D, PID: 16456079
-
Huai Q, Mazar A, Kuo A, Parry GC, Shaw DE, Callahan J, et al. Structure of human urokinase plasminogen activator in complex with its receptor. Science. 2006;311:656–9.
-
(2006)
Science
, vol.311
, pp. 656-659
-
-
Huai, Q.1
Mazar, A.2
Kuo, A.3
Parry, G.C.4
Shaw, D.E.5
Callahan, J.6
-
13
-
-
71049180369
-
Inflammatory mechanisms in ischemic stroke: therapeutic approaches
-
PID: 19919699
-
Lakhan SE, Kirchgessner A, Hofer M. Inflammatory mechanisms in ischemic stroke: therapeutic approaches. J Transl Med. 2009;7:97.
-
(2009)
J Transl Med
, vol.7
, pp. 97
-
-
Lakhan, S.E.1
Kirchgessner, A.2
Hofer, M.3
-
14
-
-
0032723531
-
Intraarterial cerebral thrombolysis for acute ischemic stroke in a community hospital
-
COI: 1:STN:280:DC%2BD3c%2FgvV2rtA%3D%3D, PID: 10543641
-
Edwards MT, Murphy MM, Geraghty JJ, Wulf JA, Konzen JP. Intraarterial cerebral thrombolysis for acute ischemic stroke in a community hospital. AJNR Am J Neuroradiol. 1999;20(9):1682–7.
-
(1999)
AJNR Am J Neuroradiol
, vol.20
, Issue.9
, pp. 1682-1687
-
-
Edwards, M.T.1
Murphy, M.M.2
Geraghty, J.J.3
Wulf, J.A.4
Konzen, J.P.5
-
15
-
-
0029070798
-
Tissue plasminogen activator (t-PA) inhibits plasmin degradation of fibrin. A mechanism that slows t-PA-mediated fibrinolysis but does not require alpha 2-antiplasmin or leakage of intrinsic plasminogen
-
COI: 1:CAS:528:DyaK2MXmtV2qsr8%3D, PID: 7769094
-
Wu JH, Diamond SL. Tissue plasminogen activator (t-PA) inhibits plasmin degradation of fibrin. A mechanism that slows t-PA-mediated fibrinolysis but does not require alpha 2-antiplasmin or leakage of intrinsic plasminogen. J Clin Invest. 1995;95(6):2483–90.
-
(1995)
J Clin Invest
, vol.95
, Issue.6
, pp. 2483-2490
-
-
Wu, J.H.1
Diamond, S.L.2
-
16
-
-
84883872986
-
Drug delivery systems for the treatment of ischemic stroke
-
COI: 1:CAS:528:DC%2BC3sXlvV2juw%3D%3D, PID: 23307348
-
Rhim T, Lee DY, Lee M. Drug delivery systems for the treatment of ischemic stroke. Pharm Res. 2013;30(10):2429–44.
-
(2013)
Pharm Res
, vol.30
, Issue.10
, pp. 2429-2444
-
-
Rhim, T.1
Lee, D.Y.2
Lee, M.3
-
17
-
-
13244271912
-
Prediction of blood–brain barrier permeation in drug discovery from in vivo, in vitro and in silico models
-
COI: 1:CAS:528:DC%2BD2MXhtlSqs7s%3D, PID: 24981621
-
Abbott NJ. Prediction of blood–brain barrier permeation in drug discovery from in vivo, in vitro and in silico models. Drug Discov Today Technol. 2004;1:407–16.
-
(2004)
Drug Discov Today Technol
, vol.1
, pp. 407-416
-
-
Abbott, N.J.1
-
18
-
-
79651475092
-
Emerging role for drug transporters at the blood brain barrier
-
PID: 21168226
-
Mruk DD, Su L, Cheng CY. Emerging role for drug transporters at the blood brain barrier. Trends Pharmacol Sci. 2010;32:99–106.
-
(2010)
Trends Pharmacol Sci
, vol.32
, pp. 99-106
-
-
Mruk, D.D.1
Su, L.2
Cheng, C.Y.3
-
19
-
-
70449718818
-
The role of the blood-CNS barrier in CNS disorders and their treatment
-
COI: 1:CAS:528:DC%2BD1MXhsVGms7vF, PID: 19664711
-
Palmer AM. The role of the blood-CNS barrier in CNS disorders and their treatment. Neurobiol Dis. 2010;37:3–12.
-
(2010)
Neurobiol Dis
, vol.37
, pp. 3-12
-
-
Palmer, A.M.1
-
20
-
-
84977771486
-
Introduction to the blood–brain barrier: methodology, biology, and pathology
-
Pardridge WM. Introduction to the blood–brain barrier: methodology, biology, and pathology. Cambridge University PRESS. 1998; 24(9):521–81.
-
(1998)
Cambridge University PRESS
, vol.24
, Issue.9
, pp. 521-581
-
-
Pardridge, W.M.1
-
21
-
-
33845784758
-
Blood–brain barrier delivery
-
COI: 1:CAS:528:DC%2BD2sXhsFOjsA%3D%3D, PID: 17198973
-
Pardridge WM. Blood–brain barrier delivery. Drug Discov Today. 2007;12:54–61.
-
(2007)
Drug Discov Today
, vol.12
, pp. 54-61
-
-
Pardridge, W.M.1
-
22
-
-
0036787074
-
Anatomical analysis of the developing cerebral vasculature in premature neonates: absence of precapillary arteriole to-venous shunts
-
PID: 12357050
-
Anstrom JA, Brown WR, Moody DM, Thore CR, Challa VR, Block SM. Anatomical analysis of the developing cerebral vasculature in premature neonates: absence of precapillary arteriole to-venous shunts. Pediatr Res. 2002;52:554–60.
-
(2002)
Pediatr Res
, vol.52
, pp. 554-560
-
-
Anstrom, J.A.1
Brown, W.R.2
Moody, D.M.3
Thore, C.R.4
Challa, V.R.5
Block, S.M.6
-
23
-
-
34547891114
-
Claudins and paracellular transport: an update
-
COI: 1:CAS:528:DC%2BD2sXhtV2rtr3M, PID: 17693762
-
Angelow S, Yu AS. Claudins and paracellular transport: an update. Curr Opin Nephrol Hypertens. 2007;16:459–64.
-
(2007)
Curr Opin Nephrol Hypertens
, vol.16
, pp. 459-464
-
-
Angelow, S.1
Yu, A.S.2
-
24
-
-
67650348496
-
Regulation and roles for claudin-family tight junction proteins
-
COI: 1:CAS:528:DC%2BD1MXktVaitbk%3D, PID: 19319969
-
Findley MK, Koval M. Regulation and roles for claudin-family tight junction proteins. IUBMB Life. 2009;61(4):431–7.
-
(2009)
IUBMB Life
, vol.61
, Issue.4
, pp. 431-437
-
-
Findley, M.K.1
Koval, M.2
-
25
-
-
29244463365
-
Astrocyte–endothelial interactions at the blood brain barrier
-
COI: 1:CAS:528:DC%2BD2MXhtlaktbjP, PID: 16371949
-
Abbott NJ, Ronnback L, Hansson E. Astrocyte–endothelial interactions at the blood brain barrier. Nat Rev Neurosci. 2006;7:41–53.
-
(2006)
Nat Rev Neurosci
, vol.7
, pp. 41-53
-
-
Abbott, N.J.1
Ronnback, L.2
Hansson, E.3
-
26
-
-
26244456551
-
Molecular biology of the blood–brain barrier
-
COI: 1:CAS:528:DC%2BD2MXktlyltrs%3D, PID: 15805577
-
Pardridge WM. Molecular biology of the blood–brain barrier. Mol Biotechnol. 2005;30:57–70.
-
(2005)
Mol Biotechnol
, vol.30
, pp. 57-70
-
-
Pardridge, W.M.1
-
27
-
-
0642311326
-
Measurement of blood–brain and blood-tumor barrier permeabilities with (14C)-labeled tracers
-
PID: 12958420
-
Asotra K, Ningaraj N, Black KL. Measurement of blood–brain and blood-tumor barrier permeabilities with (14C)-labeled tracers. Methods Mol Med. 2003;89:177–90.
-
(2003)
Methods Mol Med
, vol.89
, pp. 177-190
-
-
Asotra, K.1
Ningaraj, N.2
Black, K.L.3
-
28
-
-
12344273726
-
The blood–brain barrier: bottleneck in brain drug development
-
PID: 15717053
-
Pardridge WM. The blood–brain barrier: bottleneck in brain drug development. NeuroRx. 2005;2(1):3–14.
-
(2005)
NeuroRx
, vol.2
, Issue.1
, pp. 3-14
-
-
Pardridge, W.M.1
-
29
-
-
28244432240
-
The blood–brain barrier transmigrating single domain antibody: mechanisms of transport and antigenic epitopes in human brain endothelial cells
-
COI: 1:CAS:528:DC%2BD2MXht1OnsbrL, PID: 16271053
-
Abulrob A, Sprong H, Bergen Henegouwen PV, Stanimirovic D. The blood–brain barrier transmigrating single domain antibody: mechanisms of transport and antigenic epitopes in human brain endothelial cells. J Neurochem. 2005;95:1201–14.
-
(2005)
J Neurochem
, vol.95
, pp. 1201-1214
-
-
Abulrob, A.1
Sprong, H.2
Bergen Henegouwen, P.V.3
Stanimirovic, D.4
-
30
-
-
0037004910
-
Comparative anatomy, physiology and in vitro models of the blood–brain and blood-retina barrier
-
Schlossauer B, Steuer H. Comparative anatomy, physiology and in vitro models of the blood–brain and blood-retina barrier. Curr Med Chem. 2002;2:175–86.
-
(2002)
Curr Med Chem
, vol.2
, pp. 175-186
-
-
Schlossauer, B.1
Steuer, H.2
-
31
-
-
81755174301
-
Cytochrome P450 enzymes in the brain: emerging evidence of biological significance
-
COI: 1:CAS:528:DC%2BC3MXhsV2mu7zN, PID: 21975165
-
Ferguson CS, Tyndale RF. Cytochrome P450 enzymes in the brain: emerging evidence of biological significance. Trends Pharmacol Sci. 2011;32:708–14.
-
(2011)
Trends Pharmacol Sci
, vol.32
, pp. 708-714
-
-
Ferguson, C.S.1
Tyndale, R.F.2
-
32
-
-
58149475254
-
Brain drug-metabolizing cytochrome P450 enzymes are active in vivo, demonstrated by mechanism-based enzyme inhibition
-
COI: 1:CAS:528:DC%2BD1MXkvVartg%3D%3D, PID: 18668033
-
Miksys S, Tyndale RF. Brain drug-metabolizing cytochrome P450 enzymes are active in vivo, demonstrated by mechanism-based enzyme inhibition. Neuropsychopharmacology. 2009;34(3):634–40.
-
(2009)
Neuropsychopharmacology
, vol.34
, Issue.3
, pp. 634-640
-
-
Miksys, S.1
Tyndale, R.F.2
-
33
-
-
85047698627
-
Sniffing neuropeptides a transnasal approach to the human brain
-
COI: 1:CAS:528:DC%2BD38XjvVygu7w%3D, PID: 11992114
-
Born J, Lange T, Kern W, Mc-Gregor GP, Bickel U, Fehm HL. Sniffing neuropeptides a transnasal approach to the human brain. Nat Neurosci. 2002;5:514–6.
-
(2002)
Nat Neurosci
, vol.5
, pp. 514-516
-
-
Born, J.1
Lange, T.2
Kern, W.3
Mc-Gregor, G.P.4
Bickel, U.5
Fehm, H.L.6
-
34
-
-
77951741583
-
The role of insulin receptor signalling in synaptic plasticity and cognitive function
-
PID: 20438663
-
Huang CC, Lee CC, Hsu KS. The role of insulin receptor signalling in synaptic plasticity and cognitive function. Chang Gung Med J. 2010;33(2):115–25.
-
(2010)
Chang Gung Med J
, vol.33
, Issue.2
, pp. 115-125
-
-
Huang, C.C.1
Lee, C.C.2
Hsu, K.S.3
-
35
-
-
0035092097
-
Rapid transferrin efflux from brain to blood across the blood–brain barrier
-
COI: 1:CAS:528:DC%2BD3MXhvVCju7g%3D, PID: 11238745
-
Zhang Y, Pardridge WM. Rapid transferrin efflux from brain to blood across the blood–brain barrier. J Neurochem. 2001;76:1597–600.
-
(2001)
J Neurochem
, vol.76
, pp. 1597-1600
-
-
Zhang, Y.1
Pardridge, W.M.2
-
36
-
-
84883400046
-
The blood–brain barrier: an engineering perspective
-
Wong AD, Ye M, Levy AF, Rothstein JD, Bergles DE, Searson PC. The blood–brain barrier: an engineering perspective. Front Neuroeng. 2013;6:1–22.
-
(2013)
Front Neuroeng
, vol.6
, pp. 1-22
-
-
Wong, A.D.1
Ye, M.2
Levy, A.F.3
Rothstein, J.D.4
Bergles, D.E.5
Searson, P.C.6
-
37
-
-
0033961913
-
Transferrin and transferrin receptor function in brain barrier systems
-
Moos T, Morgan EH. Transferrin and transferrin receptor function in brain barrier systems. Cell Mol Neurobiol. 2001;20:77–95.
-
(2001)
Cell Mol Neurobiol
, vol.20
, pp. 77-95
-
-
Moos, T.1
Morgan, E.H.2
-
38
-
-
0037369812
-
Active transport of high-affinity choline and nicotine analogs into the central nervous system by the blood–brain barrier choline transporter
-
COI: 1:CAS:528:DC%2BD3sXit1eisLo%3D, PID: 12604705
-
Allen DD, Lockman PR, Roder KE, Dwoskin LP, Crooks PA. Active transport of high-affinity choline and nicotine analogs into the central nervous system by the blood–brain barrier choline transporter. J Pharmacol Exp Ther. 2003;304:1268–74.
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 1268-1274
-
-
Allen, D.D.1
Lockman, P.R.2
Roder, K.E.3
Dwoskin, L.P.4
Crooks, P.A.5
-
39
-
-
0642311333
-
A review of blood brain barrier transport techniques
-
COI: 1:CAS:528:DC%2BD3sXntlKnsbo%3D, PID: 12958421
-
Smith QR. A review of blood brain barrier transport techniques. Methods Mol Med. 2003;89:193–208.
-
(2003)
Methods Mol Med
, vol.89
, pp. 193-208
-
-
Smith, Q.R.1
-
40
-
-
31544481841
-
Structure of the blood–brain barrier and its role in the transport of amino acids
-
COI: 1:CAS:528:DC%2BD28XivFSjtg%3D%3D, PID: 16365086
-
Hawkins RA, O’Kane RL, Simpson IA, Viña JR. Structure of the blood–brain barrier and its role in the transport of amino acids. J Nutr. 2006;136(1):218S–26.
-
(2006)
J Nutr
, vol.136
, Issue.1
, pp. 218-226
-
-
Hawkins, R.A.1
O’Kane, R.L.2
Simpson, I.A.3
Viña, J.R.4
-
41
-
-
34247842999
-
Functional properties and genomics of glucose transporters
-
COI: 1:CAS:528:DC%2BD2sXht1Kntb7O, PID: 18660845
-
Zhao F-Q, Keating AF. Functional properties and genomics of glucose transporters. Curr Genomics. 2007;8:113–28.
-
(2007)
Curr Genomics
, vol.8
, pp. 113-128
-
-
Zhao, F.-Q.1
Keating, A.F.2
-
42
-
-
1942437498
-
Identification and characterization of human glucose transporter-like protein-9 (GLUT9)
-
COI: 1:CAS:528:DC%2BD2cXivF2qsbs%3D, PID: 14739288
-
Augustin R, Carayannopoules MO, Dowd LO, Phay JE, Moley JF, Moley KH. Identification and characterization of human glucose transporter-like protein-9 (GLUT9). J Biol Chem. 2004;279:16229–36.
-
(2004)
J Biol Chem
, vol.279
, pp. 16229-16236
-
-
Augustin, R.1
Carayannopoules, M.O.2
Dowd, L.O.3
Phay, J.E.4
Moley, J.F.5
Moley, K.H.6
-
43
-
-
66149130750
-
Differential receptor-mediated drug targeting to the diseased brain
-
COI: 1:CAS:528:DC%2BD1MXjslajs7k%3D, PID: 19327042
-
Rip J, Schenk GJ, Boer AG. Differential receptor-mediated drug targeting to the diseased brain. Expert Opin Drug Deliv. 2009;6:227–37.
-
(2009)
Expert Opin Drug Deliv
, vol.6
, pp. 227-237
-
-
Rip, J.1
Schenk, G.J.2
Boer, A.G.3
-
44
-
-
39749166269
-
Large neutral amino acid transporter enables brain drug delivery via prodrugs
-
COI: 1:CAS:528:DC%2BD1cXhtVaiurY%3D, PID: 18217702
-
Gynther M, Laine K, Ropponen J, Leppanen J, Mannila A, Nevalainen T, et al. Large neutral amino acid transporter enables brain drug delivery via prodrugs. J Med Chem. 2008;51(4):932–6.
-
(2008)
J Med Chem
, vol.51
, Issue.4
, pp. 932-936
-
-
Gynther, M.1
Laine, K.2
Ropponen, J.3
Leppanen, J.4
Mannila, A.5
Nevalainen, T.6
-
45
-
-
84883865879
-
Design, synthesis and brain uptake of LAT1-targeted amino acid prodrugs of dopamine
-
COI: 1:CAS:528:DC%2BC3sXntlKruw%3D%3D, PID: 24137801
-
Peura L, Malmioja K, Huttunen K, Leppanen J, Hamalainen M, Forsberg MM, et al. Design, synthesis and brain uptake of LAT1-targeted amino acid prodrugs of dopamine. Pharm Res. 2013;30(10):2523–37.
-
(2013)
Pharm Res
, vol.30
, Issue.10
, pp. 2523-2537
-
-
Peura, L.1
Malmioja, K.2
Huttunen, K.3
Leppanen, J.4
Hamalainen, M.5
Forsberg, M.M.6
-
46
-
-
80053517788
-
Large amino acid transporter 1 (LAT1) prodrugs of valproic acid: new prodrug design ideas for central nervous system delivery
-
COI: 1:CAS:528:DC%2BC3MXpvFSns70%3D, PID: 21770378
-
Peura L, Malmioja K, Laine K, Leppanen J, Gynther M, Isotalo A, et al. Large amino acid transporter 1 (LAT1) prodrugs of valproic acid: new prodrug design ideas for central nervous system delivery. Mol Pharm. 2011;8(5):1857–66.
-
(2011)
Mol Pharm
, vol.8
, Issue.5
, pp. 1857-1866
-
-
Peura, L.1
Malmioja, K.2
Laine, K.3
Leppanen, J.4
Gynther, M.5
Isotalo, A.6
-
47
-
-
84880161805
-
Receptor-mediated endocytosis and brain delivery of therapeutic biologics
-
PID: 23840214, 14 pages
-
Xiao G, Gan L-S. Receptor-mediated endocytosis and brain delivery of therapeutic biologics. Int J Cell Biol. 2013;2013, 703545. 14 pages.
-
(2013)
Int J Cell Biol
, vol.2013
-
-
Xiao, G.1
Gan, L.-S.2
-
48
-
-
19444381236
-
Delivery of β-galactosidase to mouse brain via the blood–brain barrier transferrin receptor
-
COI: 1:CAS:528:DC%2BD2MXkslekt7s%3D, PID: 15718287
-
Zhang Y, Pardridge WM. Delivery of β-galactosidase to mouse brain via the blood–brain barrier transferrin receptor. J Pharmacol Exp Ther. 2005;313:1075–81.
-
(2005)
J Pharmacol Exp Ther
, vol.313
, pp. 1075-1081
-
-
Zhang, Y.1
Pardridge, W.M.2
-
50
-
-
0035947033
-
In vitro demonstration of a saturable transport system for leptin across the blood–brain barrier
-
COI: 1:CAS:528:DC%2BD3MXktFOqtbc%3D, PID: 11411806
-
Maresh GA, Maness LM, Zadina JE, Kastin AJ. In vitro demonstration of a saturable transport system for leptin across the blood–brain barrier. Life Sci. 2001;69(1):67–73.
-
(2001)
Life Sci
, vol.69
, Issue.1
, pp. 67-73
-
-
Maresh, G.A.1
Maness, L.M.2
Zadina, J.E.3
Kastin, A.J.4
-
51
-
-
0036889760
-
Targeted drug delivery via the transferrin receptor mediated endocytosis pathway
-
COI: 1:CAS:528:DC%2BD38Xps1Grs7k%3D, PID: 12429868
-
Qian ZM, Li H, Sun H, Ho K. Targeted drug delivery via the transferrin receptor mediated endocytosis pathway. Pharmacol Rev. 2002;54(4):561–87.
-
(2002)
Pharmacol Rev
, vol.54
, Issue.4
, pp. 561-587
-
-
Qian, Z.M.1
Li, H.2
Sun, H.3
Ho, K.4
-
52
-
-
0036238011
-
Transferrin/transferrin receptor-mediated drug delivery
-
COI: 1:CAS:528:DC%2BD38XjslGru78%3D, PID: 11933019
-
Li H, Qian ZM. Transferrin/transferrin receptor-mediated drug delivery. Med Res Rev. 2002;22(3):225–50.
-
(2002)
Med Res Rev
, vol.22
, Issue.3
, pp. 225-250
-
-
Li, H.1
Qian, Z.M.2
-
53
-
-
0037022588
-
Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis
-
COI: 1:CAS:528:DC%2BD38Xit1Cqs7w%3D, PID: 11867720
-
Waheed A, Grubb JH, Zhou XY, Tomatsu S, Fleming RE, Costaldi ME, et al. Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis. Proc Natl Acad Sci. 2002;99(5):3117–22.
-
(2002)
Proc Natl Acad Sci
, vol.99
, Issue.5
, pp. 3117-3122
-
-
Waheed, A.1
Grubb, J.H.2
Zhou, X.Y.3
Tomatsu, S.4
Fleming, R.E.5
Costaldi, M.E.6
-
54
-
-
59649102668
-
Transferrin- and transferrin-receptor antibody-modified nanoparticles enable drug delivery across the blood–brain barrier (BBB)
-
Karsten U, Telli H, Elisabeth H, Jorg K. Transferrin- and transferrin-receptor antibody-modified nanoparticles enable drug delivery across the blood–brain barrier (BBB). Eur J Pharm Biopharm. 2009;71(2):251–6.
-
(2009)
Eur J Pharm Biopharm
, vol.71
, Issue.2
, pp. 251-256
-
-
Karsten, U.1
Telli, H.2
Elisabeth, H.3
Jorg, K.4
-
55
-
-
12544256444
-
Receptor-mediated endocytosis and intracellular trafficking of lipoproteins and transferrin in insect cells
-
PID: 15681222
-
Van Hoof D, Rodenburg KW, Van der Horst DJ. Receptor-mediated endocytosis and intracellular trafficking of lipoproteins and transferrin in insect cells. Insect Biochem Mol Biol. 2005;35(2):117–28.
-
(2005)
Insect Biochem Mol Biol
, vol.35
, Issue.2
, pp. 117-128
-
-
Van Hoof, D.1
Rodenburg, K.W.2
Van der Horst, D.J.3
-
56
-
-
33846897981
-
Humanization of anti-human insulin receptor antibody for drug targeting across the human blood–brain barrier
-
COI: 1:CAS:528:DC%2BD2sXpsFShtA%3D%3D, PID: 16937408
-
Boado RJ, Zhang Y, Zhang Y, Pardridge WM. Humanization of anti-human insulin receptor antibody for drug targeting across the human blood–brain barrier. Biotechnol Bioeng. 2007;96(2):381–91.
-
(2007)
Biotechnol Bioeng
, vol.96
, Issue.2
, pp. 381-391
-
-
Boado, R.J.1
Zhang, Y.2
Zhang, Y.3
Pardridge, W.M.4
-
57
-
-
0033996507
-
Transport across the primate blood–brain barrier of a genetically engineered chimeric monoclonal antibody to the human insulin receptor
-
COI: 1:CAS:528:DC%2BD3cXivVKls7c%3D, PID: 10801214
-
Coloma MJ, Lee HJ, Landaw EM, Boado RJ, Morrison SL, Pardridge WM. Transport across the primate blood–brain barrier of a genetically engineered chimeric monoclonal antibody to the human insulin receptor. Pharm Res. 2000;17(3):266–74.
-
(2000)
Pharm Res
, vol.17
, Issue.3
, pp. 266-274
-
-
Coloma, M.J.1
Lee, H.J.2
Landaw, E.M.3
Boado, R.J.4
Morrison, S.L.5
Pardridge, W.M.6
-
58
-
-
44449128659
-
GDNF fusion protein for targeted-drug delivery across the human blood–brain barrier
-
Boado RJ, Zhang Y, Zhang Y, Wang Y, Pardridge WM. GDNF fusion protein for targeted-drug delivery across the human blood–brain barrier. Biotech Bioeng. 2007;100:387–96.
-
(2007)
Biotech Bioeng
, vol.100
, pp. 387-396
-
-
Boado, R.J.1
Zhang, Y.2
Zhang, Y.3
Wang, Y.4
Pardridge, W.M.5
-
59
-
-
1942453793
-
Potential role of the low-density lipoprotein receptor family as mediators of cellular drug uptake
-
COI: 1:CAS:528:DC%2BD2cXjtl2ktrc%3D, PID: 15109771
-
Chung NS, Wasan KM. Potential role of the low-density lipoprotein receptor family as mediators of cellular drug uptake. Adv Drug Deliv Rev. 2004;56(9):1315–34.
-
(2004)
Adv Drug Deliv Rev
, vol.56
, Issue.9
, pp. 1315-1334
-
-
Chung, N.S.1
Wasan, K.M.2
-
60
-
-
48749095941
-
Involvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector angiopep-2
-
COI: 1:CAS:528:DC%2BD1cXhtVegtL3L, PID: 18489712
-
Demeule M, Currie JC, Bertrand Y, Che C, Regina A, Gabathuler R, et al. Involvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector angiopep-2. J Neurochem. 2008;106(4):1534–44.
-
(2008)
J Neurochem
, vol.106
, Issue.4
, pp. 1534-1544
-
-
Demeule, M.1
Currie, J.C.2
Bertrand, Y.3
Che, C.4
Regina, A.5
Gabathuler, R.6
-
61
-
-
34247557490
-
The LDL receptor-related protein (LRP) family: an old family of proteins with new physiological functions
-
COI: 1:CAS:528:DC%2BD2sXmt1Cqs7w%3D, PID: 17457719
-
May P, Woldt E, Matz RL, Boucher P. The LDL receptor-related protein (LRP) family: an old family of proteins with new physiological functions. Ann Med. 2007;39(3):219–28.
-
(2007)
Ann Med
, vol.39
, Issue.3
, pp. 219-228
-
-
May, P.1
Woldt, E.2
Matz, R.L.3
Boucher, P.4
-
62
-
-
34548496491
-
Low-density lipoprotein receptor-related protein promotes amyloid precursor protein trafficking to lipid rafts in the endocytic pathway
-
COI: 1:CAS:528:DC%2BD2sXhtVehu77P, PID: 17463224
-
Yoon IS, Chen E, Busse T, Repetto E, Lakshmana MK, Koo EH, et al. Low-density lipoprotein receptor-related protein promotes amyloid precursor protein trafficking to lipid rafts in the endocytic pathway. FASEB J. 2007;21:2742–52.
-
(2007)
FASEB J
, vol.21
, pp. 2742-2752
-
-
Yoon, I.S.1
Chen, E.2
Busse, T.3
Repetto, E.4
Lakshmana, M.K.5
Koo, E.H.6
-
63
-
-
26844507074
-
Low density lipoprotein receptor-related proteins (LRPs), Alzheimer’s and cognition
-
COI: 1:CAS:528:DC%2BD2MXhtV2gsL3N, PID: 16266282
-
Harris-White ME, Frautschy SA. Low density lipoprotein receptor-related proteins (LRPs), Alzheimer’s and cognition. Curr Drug Targets CNS Neurol Disord. 2005;4(5):469–80.
-
(2005)
Curr Drug Targets CNS Neurol Disord
, vol.4
, Issue.5
, pp. 469-480
-
-
Harris-White, M.E.1
Frautschy, S.A.2
-
64
-
-
33646438600
-
Diphtheria toxin receptor-targeted brain drug delivery
-
COI: 1:CAS:528:DC%2BD1cXhvVOhurs%3D
-
Gaillard PJ, Brink A, Boer AG. Diphtheria toxin receptor-targeted brain drug delivery. Int Congr Ser. 2005;1277:185–95.
-
(2005)
Int Congr Ser
, vol.1277
, pp. 185-195
-
-
Gaillard, P.J.1
Brink, A.2
Boer, A.G.3
-
65
-
-
0028298886
-
Expression and function of the low density lipoprotein receptor-related protein (LRP) in mammalian central neuron
-
COI: 1:CAS:528:DyaK2cXksl2itb4%3D
-
Bu G, Maksymovitch EA, Nerbonne JM, Schwartz AL. Expression and function of the low density lipoprotein receptor-related protein (LRP) in mammalian central neuron. J Biochem. 1994;269:18521–8.
-
(1994)
J Biochem
, vol.269
, pp. 18521-18528
-
-
Bu, G.1
Maksymovitch, E.A.2
Nerbonne, J.M.3
Schwartz, A.L.4
-
66
-
-
0031561480
-
Heparin-binding EGF like growth factor
-
COI: 1:CAS:528:DyaK2sXnsFyrsrk%3D, PID: 9426203
-
Raab G, Klagsbrun M. Heparin-binding EGF like growth factor. Biochim Biophys Acta. 1997;1333:F179–99.
-
(1997)
Biochim Biophys Acta
, vol.1333
, pp. 179-199
-
-
Raab, G.1
Klagsbrun, M.2
-
67
-
-
0031951510
-
Tissue plasminogen activator (t-PA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice
-
COI: 1:STN:280:DyaK1c7itFSqtA%3D%3D, PID: 9461198
-
Wang YF, Tsirka SE, Strickland S, Stieg PE, Soriano SG, Lipton SA. Tissue plasminogen activator (t-PA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice. Nat Med. 1998;4(2):228–31.
-
(1998)
Nat Med
, vol.4
, Issue.2
, pp. 228-231
-
-
Wang, Y.F.1
Tsirka, S.E.2
Strickland, S.3
Stieg, P.E.4
Soriano, S.G.5
Lipton, S.A.6
-
68
-
-
77951731600
-
Safety of t-PA in stroke mimics and neuroimaging-negative cerebral ischemia
-
COI: 1:CAS:528:DC%2BC3cXlsVOgsL4%3D, PID: 20335564
-
Chernyshev OY, Martin-Schild S, Albright KC, Barreto A, Misra V, Acosta Grotta JC, et al. Safety of t-PA in stroke mimics and neuroimaging-negative cerebral ischemia. Neurology. 2010;74(17):1340–5.
-
(2010)
Neurology
, vol.74
, Issue.17
, pp. 1340-1345
-
-
Chernyshev, O.Y.1
Martin-Schild, S.2
Albright, K.C.3
Barreto, A.4
Misra, V.5
Acosta Grotta, J.C.6
-
69
-
-
79952663249
-
Role of tissue plasminogen activator in acute ischemic stroke
-
COI: 1:CAS:528:DC%2BC3MXksVGktL8%3D, PID: 21386027
-
Hatcher MA, Starr JA. Role of tissue plasminogen activator in acute ischemic stroke. Ann Pharmacother. 2011;45(3):364–71.
-
(2011)
Ann Pharmacother
, vol.45
, Issue.3
, pp. 364-371
-
-
Hatcher, M.A.1
Starr, J.A.2
-
70
-
-
74149095001
-
Intravenous tissue plasminogen activator for stroke: a review of the ECASS III results in relation to prior clinical trials
-
PID: 19765940
-
Cronin CA. Intravenous tissue plasminogen activator for stroke: a review of the ECASS III results in relation to prior clinical trials. J Emerg Med. 2010;38(1):99–105.
-
(2010)
J Emerg Med
, vol.38
, Issue.1
, pp. 99-105
-
-
Cronin, C.A.1
-
71
-
-
70350228571
-
Prospects of thrombolytic therapy for acute ischemic stroke
-
PID: 19803399
-
Nakashima T, Minematsu K. Prospects of thrombolytic therapy for acute ischemic stroke. Brain Nerve. 2009;61(9):1003–12.
-
(2009)
Brain Nerve
, vol.61
, Issue.9
, pp. 1003-1012
-
-
Nakashima, T.1
Minematsu, K.2
-
72
-
-
0023616913
-
Development and evaluation of anisoylated plasminogen streptokinase activator complex (APSAC) as a second generation thrombolytic agent
-
COI: 1:CAS:528:DyaL1cXkvVGisg%3D%3D, PID: 3312369
-
Anderson JL. Development and evaluation of anisoylated plasminogen streptokinase activator complex (APSAC) as a second generation thrombolytic agent. J Am Coll Cardiol. 1987;10(5 Suppl B):22B–7.
-
(1987)
J Am Coll Cardiol
, vol.10
, pp. 22-27
-
-
Anderson, J.L.1
-
73
-
-
0023180607
-
Anisoylated plasminogen streptokinase activator complex (APSAC). A review of its mechanism of action, clinical pharmacology and therapeutic use in acute myocardial infarction
-
COI: 1:STN:280:DyaL1c%2FgsVWrug%3D%3D, PID: 3308411
-
Monk JP, Heel RC. Anisoylated plasminogen streptokinase activator complex (APSAC). A review of its mechanism of action, clinical pharmacology and therapeutic use in acute myocardial infarction. Drugs. 1987;34(1):25–49.
-
(1987)
Drugs
, vol.34
, Issue.1
, pp. 25-49
-
-
Monk, J.P.1
Heel, R.C.2
-
74
-
-
0031941584
-
Staphylokinase: a potent, uniquely fibrin-selective thrombolytic agent
-
COI: 1:CAS:528:DyaK1cXhs1Gqu7k%3D, PID: 9500599
-
Collen D. Staphylokinase: a potent, uniquely fibrin-selective thrombolytic agent. Nat Med. 1998;4(3):279–84.
-
(1998)
Nat Med
, vol.4
, Issue.3
, pp. 279-284
-
-
Collen, D.1
-
75
-
-
0345283158
-
Clinical development of PEGylated recombinant staphylokinase (PEG-Sak) for bolus thrombolytic treatment of patients with acute myocardial infarction
-
COI: 1:CAS:528:DC%2BD3sXnt1yqtro%3D, PID: 14499711
-
Moreadith RW, Collen D. Clinical development of PEGylated recombinant staphylokinase (PEG-Sak) for bolus thrombolytic treatment of patients with acute myocardial infarction. Adv Drug Deliv Rev. 2003;55(10):1337–45.
-
(2003)
Adv Drug Deliv Rev
, vol.55
, Issue.10
, pp. 1337-1345
-
-
Moreadith, R.W.1
Collen, D.2
-
76
-
-
8344247667
-
Alternative sources of fibrinolytic, anticoagulative, antimicrobial and anticancer molecules
-
COI: 1:CAS:528:DC%2BD2cXhtFCqu7bK, PID: 15461857
-
Cooper EL, Hrzenjak TM, Grdisa T. Alternative sources of fibrinolytic, anticoagulative, antimicrobial and anticancer molecules. Int J Immunopathol Pharmacol. 2004;17:237–44.
-
(2004)
Int J Immunopathol Pharmacol
, vol.17
, pp. 237-244
-
-
Cooper, E.L.1
Hrzenjak, T.M.2
Grdisa, T.3
-
77
-
-
0042861787
-
Purification, characterization and crystallization of a group of earthworm fibrinolytic enzymes from Eisenia fetida
-
COI: 1:CAS:528:DC%2BD3sXksFWnu7k%3D, PID: 12889822
-
Wang F, Wang C, Li M, Gui L, Zhang J, Chang W. Purification, characterization and crystallization of a group of earthworm fibrinolytic enzymes from Eisenia fetida. Biotechnol Lett. 2003;25:1105–9.
-
(2003)
Biotechnol Lett
, vol.25
, pp. 1105-1109
-
-
Wang, F.1
Wang, C.2
Li, M.3
Gui, L.4
Zhang, J.5
Chang, W.6
-
78
-
-
79960734368
-
A new thrombolytic agent, monteplase, is independent of plasminogen activator inhibitor in patients with acute myocardial infarction: comparison with native t-PA E 610
-
Inoue T, Yaguchi I, Takayangi K, Hayashi T, Moorrks S, Eguchi Y. A new thrombolytic agent, monteplase, is independent of plasminogen activator inhibitor in patients with acute myocardial infarction: comparison with native t-PA E 610. J Am Coll Cardiol. 1997;29:1447–53.
-
(1997)
J Am Coll Cardiol
, vol.29
, pp. 1447-1453
-
-
Inoue, T.1
Yaguchi, I.2
Takayangi, K.3
Hayashi, T.4
Moorrks, S.5
Eguchi, Y.6
-
79
-
-
33646442324
-
The cardio-protective effect and mechanism of lumbrokinase
-
COI: 1:CAS:528:DC%2BD2sXnsFGqtLc%3D, PID: 16758997
-
Sun HL, Jiao JD, Pan ZW, Dong DL, Yang FB. The cardio-protective effect and mechanism of lumbrokinase. Yao Xue Xue Bao. 2006;41(3):247–51.
-
(2006)
Yao Xue Xue Bao
, vol.41
, Issue.3
, pp. 247-251
-
-
Sun, H.L.1
Jiao, J.D.2
Pan, Z.W.3
Dong, D.L.4
Yang, F.B.5
-
80
-
-
0034013433
-
Activation of the JAK/STAT pathway following transient focal cerebral ischemia: signaling through Jak1 and Stat3 in astrocytes
-
COI: 1:STN:280:DC%2BD3c3hvFSlsw%3D%3D, PID: 10756075
-
Justicia C, Gabriel C, Planas AM. Activation of the JAK/STAT pathway following transient focal cerebral ischemia: signaling through Jak1 and Stat3 in astrocytes. Glia. 2000;30:253–70.
-
(2000)
Glia
, vol.30
, pp. 253-270
-
-
Justicia, C.1
Gabriel, C.2
Planas, A.M.3
-
81
-
-
0034617442
-
Antiplatelet mechanisms of TA-993 and its metabolite MB3 in ADP-induced platelet aggregation
-
COI: 1:CAS:528:DC%2BD3cXksFGitrw%3D, PID: 10884507
-
Katoh M, Karasawa T, Doi H, Odawara A, Takagi M, Ikeo T, et al. Antiplatelet mechanisms of TA-993 and its metabolite MB3 in ADP-induced platelet aggregation. Eur J Pharmacol. 2000;399:91–6.
-
(2000)
Eur J Pharmacol
, vol.399
, pp. 91-96
-
-
Katoh, M.1
Karasawa, T.2
Doi, H.3
Odawara, A.4
Takagi, M.5
Ikeo, T.6
-
82
-
-
0032510743
-
Signal transduction and activator of transcription (STAT) protein-dependent activation of angiotensinogen promoter: a cellular signal for hypertrophy in cardiac muscle
-
COI: 1:CAS:528:DyaK1cXjtFWktb0%3D, PID: 9576927
-
Mascareno E, Dhar M, Siddiqui MA. Signal transduction and activator of transcription (STAT) protein-dependent activation of angiotensinogen promoter: a cellular signal for hypertrophy in cardiac muscle. Proc Natl Acad Sci. 1998;95:5590–4.
-
(1998)
Proc Natl Acad Sci
, vol.95
, pp. 5590-5594
-
-
Mascareno, E.1
Dhar, M.2
Siddiqui, M.A.3
-
83
-
-
33846245504
-
Preventing stroke: saving lives around the world
-
PID: 17239805
-
Strong K, Mathers C, Bonita R. Preventing stroke: saving lives around the world. Lancet Neurol. 2007;6:182–7.
-
(2007)
Lancet Neurol
, vol.6
, pp. 182-187
-
-
Strong, K.1
Mathers, C.2
Bonita, R.3
-
84
-
-
24144477985
-
The effect of lumbrokinase on P-selectin and E-selectin in cerebral ischemia model of rat
-
PID: 12875085
-
Zhang X, Zhang J, Kuang P, Lang S, Wu W, et al. The effect of lumbrokinase on P-selectin and E-selectin in cerebral ischemia model of rat. J Tradit Chin Med. 2003;23:141–6.
-
(2003)
J Tradit Chin Med
, vol.23
, pp. 141-146
-
-
Zhang, X.1
Zhang, J.2
Kuang, P.3
Lang, S.4
Wu, W.5
-
85
-
-
0034117736
-
Thrombolytic reversal of acute human cerebral ischemic injury shown by diffusion/perfusion magnetic resonance imaging
-
COI: 1:STN:280:DC%2BD3c3it1yisw%3D%3D, PID: 10762157
-
Kidwell CS, Saver JL, Mattiello J, Starkman S, Vinuela F, Duckwiler G, et al. Thrombolytic reversal of acute human cerebral ischemic injury shown by diffusion/perfusion magnetic resonance imaging. Ann Neurol. 2000;47(4):462–9.
-
(2000)
Ann Neurol
, vol.47
, Issue.4
, pp. 462-469
-
-
Kidwell, C.S.1
Saver, J.L.2
Mattiello, J.3
Starkman, S.4
Vinuela, F.5
Duckwiler, G.6
-
86
-
-
0042282011
-
Trial design and reporting standards for intra-arterial cerebral thrombolysis for acute ischemic stroke
-
PID: 12869717
-
Higashida RT, Furlan AJ, Roberts H, Tomsick T, Connors B, Barr J, et al. Trial design and reporting standards for intra-arterial cerebral thrombolysis for acute ischemic stroke. Stroke. 2003;34(8):e109–37.
-
(2003)
Stroke
, vol.34
, Issue.8
, pp. 109-137
-
-
Higashida, R.T.1
Furlan, A.J.2
Roberts, H.3
Tomsick, T.4
Connors, B.5
Barr, J.6
-
87
-
-
0034035399
-
Monitoring intravenous recombinant tissue plasminogen activator thrombolysis for acute ischemic stroke with diffusion and perfusion MRI
-
COI: 1:CAS:528:DC%2BD3cXkt1Cntrk%3D, PID: 10835451
-
Schellinger PD, Jansen O, Fiebach JB, Heiland S, Steiner T, Schwab S, et al. Monitoring intravenous recombinant tissue plasminogen activator thrombolysis for acute ischemic stroke with diffusion and perfusion MRI. Stroke. 2000;31(6):1318–28.
-
(2000)
Stroke
, vol.31
, Issue.6
, pp. 1318-1328
-
-
Schellinger, P.D.1
Jansen, O.2
Fiebach, J.B.3
Heiland, S.4
Steiner, T.5
Schwab, S.6
-
88
-
-
84891833039
-
Stroke-induced brain parenchymal injury drives blood–brain barrier early leakage kinetics: a combined in vivo/in vitro study
-
PID: 24084699
-
Kuntz M, Mysiorek C, Pétrault O, Petrault M, Uzbekov R, Bordet R, et al. Stroke-induced brain parenchymal injury drives blood–brain barrier early leakage kinetics: a combined in vivo/in vitro study. J Cereb Blood Flow Metab. 2014;34:95–107.
-
(2014)
J Cereb Blood Flow Metab
, vol.34
, pp. 95-107
-
-
Kuntz, M.1
Mysiorek, C.2
Pétrault, O.3
Petrault, M.4
Uzbekov, R.5
Bordet, R.6
-
89
-
-
33644818304
-
1,026 experimental treatments in acute stroke
-
PID: 16453316
-
O’Collins VE, Macleod MR, Donnan GA, Horky LL, Van Der Worp BH, Howells DW. 1,026 experimental treatments in acute stroke. Ann Neurol. 2006;59:467–77.
-
(2006)
Ann Neurol
, vol.59
, pp. 467-477
-
-
O’Collins, V.E.1
Macleod, M.R.2
Donnan, G.A.3
Horky, L.L.4
Van Der Worp, B.H.5
Howells, D.W.6
-
91
-
-
84866527214
-
Pathobiology of injury after stroke: the neurovascular unit and beyond
-
PID: 22994217
-
Dirnagl U. Pathobiology of injury after stroke: the neurovascular unit and beyond. Ann N Y Acad Sci. 2012;1268:21–5.
-
(2012)
Ann N Y Acad Sci
, vol.1268
, pp. 21-25
-
-
Dirnagl, U.1
-
92
-
-
0035554149
-
Temporal kinetics of calcium in neocortical neuronal nuclei after global cerebral ischemia and reperfusion. An ultrastructural study
-
COI: 1:CAS:528:DC%2BD38Xjs1SqsLk%3D, PID: 12092097
-
Franko J, Pomfy M, Prosbova T, Kimakova T. Temporal kinetics of calcium in neocortical neuronal nuclei after global cerebral ischemia and reperfusion. An ultrastructural study. Sb Lek. 2001;102(2):149–52.
-
(2001)
Sb Lek
, vol.102
, Issue.2
, pp. 149-152
-
-
Franko, J.1
Pomfy, M.2
Prosbova, T.3
Kimakova, T.4
-
93
-
-
34250744722
-
Central nervous system drug disposition: the relationship between in situ brain permeability and brain free fraction
-
COI: 1:CAS:528:DC%2BD2sXntl2jt7g%3D, PID: 17405866
-
Summerfield SG, Read K, Begley DJ, Obradovic T, Hidalgo IJ, Coggon S. Central nervous system drug disposition: the relationship between in situ brain permeability and brain free fraction. J Pharmacol Exp Ther. 2007;322:205–13.
-
(2007)
J Pharmacol Exp Ther
, vol.322
, pp. 205-213
-
-
Summerfield, S.G.1
Read, K.2
Begley, D.J.3
Obradovic, T.4
Hidalgo, I.J.5
Coggon, S.6
-
94
-
-
0035468033
-
Physicochemical profiling (solubility, permeability and charge state)
-
COI: 1:CAS:528:DC%2BD3MXms1Khs7o%3D, PID: 11899112
-
Avdeef A. Physicochemical profiling (solubility, permeability and charge state). Curr Top Med Chem. 2001;1:277–351.
-
(2001)
Curr Top Med Chem
, vol.1
, pp. 277-351
-
-
Avdeef, A.1
-
95
-
-
70349408777
-
New strategies to deliver anticancer drugs to brain tumors
-
COI: 1:CAS:528:DC%2BD1MXhtFGhurzI, PID: 19732031
-
Laquintana V. New strategies to deliver anticancer drugs to brain tumors. Expert Opin Drug Deliv. 2009;6(10):1017–32.
-
(2009)
Expert Opin Drug Deliv
, vol.6
, Issue.10
, pp. 1017-1032
-
-
Laquintana, V.1
-
96
-
-
0033526159
-
Vector mediated drug delivery to the brain
-
COI: 1:CAS:528:DyaK1MXhvVCnsrs%3D, PID: 10837722
-
Pardridge W. Vector mediated drug delivery to the brain. Adv Drug Deliv Rev. 1999;36:299–321.
-
(1999)
Adv Drug Deliv Rev
, vol.36
, pp. 299-321
-
-
Pardridge, W.1
-
97
-
-
0028821715
-
New variant of human tissue plasminogen activator (TPA) with enhanced efficacy and lower incidence of bleeding compared with recombinant human TPA
-
COI: 1:CAS:528:DyaK28XitlSltw%3D%3D, PID: 7586274
-
Benedict CR, Refino CJ, Keyt BA, Pakala R, Paoni NF, Thomas GR, et al. New variant of human tissue plasminogen activator (TPA) with enhanced efficacy and lower incidence of bleeding compared with recombinant human TPA. Circulation. 1995;92:3032–40.
-
(1995)
Circulation
, vol.92
, pp. 3032-3040
-
-
Benedict, C.R.1
Refino, C.J.2
Keyt, B.A.3
Pakala, R.4
Paoni, N.F.5
Thomas, G.R.6
-
98
-
-
84861985853
-
TPA-S481A prevents neurotoxicity of endogenous tPA in traumatic brain injury
-
PID: 22435890
-
Armstead WM, Riley J, Yarovoi S, Cines DB, Smith DH, Higazi AA. TPA-S481A prevents neurotoxicity of endogenous tPA in traumatic brain injury. J Neurotrauma. 2012;29(9):1794–802.
-
(2012)
J Neurotrauma
, vol.29
, Issue.9
, pp. 1794-1802
-
-
Armstead, W.M.1
Riley, J.2
Yarovoi, S.3
Cines, D.B.4
Smith, D.H.5
Higazi, A.A.6
-
99
-
-
4444377604
-
Neonatal mice lacking functional Fas death receptors are resistant to hypoxic-ischemic brain injury
-
COI: 1:CAS:528:DC%2BD2cXntlaru7c%3D, PID: 15350969
-
Graham EM, Sheldon RA, Flock DL, Ferriero DM, Martin LJ, O’Riordan DP, et al. Neonatal mice lacking functional Fas death receptors are resistant to hypoxic-ischemic brain injury. Neurobiol Dis. 2004;17(1):89–98.
-
(2004)
Neurobiol Dis
, vol.17
, Issue.1
, pp. 89-98
-
-
Graham, E.M.1
Sheldon, R.A.2
Flock, D.L.3
Ferriero, D.M.4
Martin, L.J.5
O’Riordan, D.P.6
-
100
-
-
84880182010
-
LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype
-
COI: 1:CAS:528:DC%2BC3sXht1ygurjI, PID: 23866919
-
Maier W, Bednorz M, Meister S, Roebroek A, Weggen S, Schmitt U, et al. LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype. Mol Neurodegener. 2013;8:25.
-
(2013)
Mol Neurodegener
, vol.8
, pp. 25
-
-
Maier, W.1
Bednorz, M.2
Meister, S.3
Roebroek, A.4
Weggen, S.5
Schmitt, U.6
-
101
-
-
84870309846
-
Neurological disorders and therapeutics targeted to surmount the blood–brain barrier
-
COI: 1:CAS:528:DC%2BC38XhtVKkurjP, PID: 22848160
-
Kanwar JR, Sriramoju B, Kanwar RK. Neurological disorders and therapeutics targeted to surmount the blood–brain barrier. Int J Nanomedicine. 2012;7:3259–78.
-
(2012)
Int J Nanomedicine
, vol.7
, pp. 3259-3278
-
-
Kanwar, J.R.1
Sriramoju, B.2
Kanwar, R.K.3
-
102
-
-
77949375780
-
Biopharmaceutical drug targeting to the brain
-
COI: 1:CAS:528:DC%2BC3cXivFeks78%3D, PID: 20064077
-
Pardridge WM. Biopharmaceutical drug targeting to the brain. J Drug Target. 2010;18(3):157–67.
-
(2010)
J Drug Target
, vol.18
, Issue.3
, pp. 157-167
-
-
Pardridge, W.M.1
-
103
-
-
49149127640
-
Coordination of thrombolytic pro-ala-lys peptides with Cu (II): leading to nanoscale self-assembly, increase of thrombolytic activity and additional vasodilation
-
COI: 1:CAS:528:DC%2BD1cXntVyntL0%3D, PID: 18547100
-
Ren X, Cui G, Zhao M, Wang C, Peng S. Coordination of thrombolytic pro-ala-lys peptides with Cu (II): leading to nanoscale self-assembly, increase of thrombolytic activity and additional vasodilation. J Phys Chem B. 2008;112(27):8174–80.
-
(2008)
J Phys Chem B
, vol.112
, Issue.27
, pp. 8174-8180
-
-
Ren, X.1
Cui, G.2
Zhao, M.3
Wang, C.4
Peng, S.5
-
104
-
-
79959919390
-
A fibrin-specific thrombolytic nanomedicine approach to acute ischemic stroke
-
COI: 1:CAS:528:DC%2BC3MXpsVajtrg%3D
-
Marsh JN, Hu G, Scott MJ, Zhang H, Goette MJ, Gaffney PJ, et al. A fibrin-specific thrombolytic nanomedicine approach to acute ischemic stroke. Nanomedicine (London). 2011;6(4):605–15.
-
(2011)
Nanomedicine (London)
, vol.6
, Issue.4
, pp. 605-615
-
-
Marsh, J.N.1
Hu, G.2
Scott, M.J.3
Zhang, H.4
Goette, M.J.5
Gaffney, P.J.6
-
105
-
-
34249690076
-
Molecular imaging with targeted perfluorocarbon nanoparticles: quantification of the concentration dependence of contrast enhancement for binding to sparse cellular epitopes
-
PID: 17434667
-
Marsh JN, Partlow KC, Abendschein DR, Scott MJ, Lanza GM, Wickline SA. Molecular imaging with targeted perfluorocarbon nanoparticles: quantification of the concentration dependence of contrast enhancement for binding to sparse cellular epitopes. Ultrasound Med Biol. 2007;33(6):950–8.
-
(2007)
Ultrasound Med Biol
, vol.33
, Issue.6
, pp. 950-958
-
-
Marsh, J.N.1
Partlow, K.C.2
Abendschein, D.R.3
Scott, M.J.4
Lanza, G.M.5
Wickline, S.A.6
-
106
-
-
1642279961
-
Ultrasound-enhanced thrombolysis for acute ischemic stroke: phase I. Findings of the CLOTBUST trial
-
PID: 15095555
-
Alexandrov AV, Demchuk AM, Burgin WS, Robinson DJ, Grotta JC, CLOTBUST Investigators. Ultrasound-enhanced thrombolysis for acute ischemic stroke: phase I. Findings of the CLOTBUST trial. J Neuroimaging. 2004;14(2):113–7.
-
(2004)
J Neuroimaging
, vol.14
, Issue.2
, pp. 113-117
-
-
Alexandrov, A.V.1
Demchuk, A.M.2
Burgin, W.S.3
Robinson, D.J.4
Grotta, J.C.5
CLOTBUST Investigators6
-
107
-
-
0036858484
-
Ultrasound-enhanced thrombolysis for stroke: clinical significance
-
PID: 12470858
-
Alexandrov AV. Ultrasound-enhanced thrombolysis for stroke: clinical significance. Eur J Ultrasound. 2002;16(1–2):131–40.
-
(2002)
Eur J Ultrasound
, vol.16
, Issue.1-2
, pp. 131-140
-
-
Alexandrov, A.V.1
-
108
-
-
33646714392
-
Ultrasound enhanced thrombolysis for stroke
-
Alexandrov AV. Ultrasound enhanced thrombolysis for stroke. Int J Stroke. 2005;1(1):26–9.
-
(2005)
Int J Stroke
, vol.1
, Issue.1
, pp. 26-29
-
-
Alexandrov, A.V.1
-
109
-
-
84857533781
-
Gene therapy for ischemic heart disease: review of clinical trials
-
PID: 22358281
-
Eibel B, Rodrigues CG, Giusti II, Nesralla IA, Prates PR, Sant Anna RT, et al. Gene therapy for ischemic heart disease: review of clinical trials. Rev Bras Cir Cardiovasc. 2011;26(4):635–46.
-
(2011)
Rev Bras Cir Cardiovasc
, vol.26
, Issue.4
, pp. 635-646
-
-
Eibel, B.1
Rodrigues, C.G.2
Giusti, I.I.3
Nesralla, I.A.4
Prates, P.R.5
Sant Anna, R.T.6
-
110
-
-
0037494727
-
Recent advances in adenovirus-mediated gene therapy for cerebral ischemia
-
PID: 12553534
-
Masumu M, Hata R. Recent advances in adenovirus-mediated gene therapy for cerebral ischemia. Curr Gene Ther. 2003;3(1):43–8.
-
(2003)
Curr Gene Ther
, vol.3
, Issue.1
, pp. 43-48
-
-
Masumu, M.1
Hata, R.2
-
111
-
-
0034942540
-
Gene therapy for treatment of cerebral ischemia using defective herpes simplex viral vectors
-
COI: 1:CAS:528:DC%2BD3MXlsV2ksLs%3D, PID: 11462790
-
Yenari MA, Dumas TC, Sapolsky RM, Steinberg GK. Gene therapy for treatment of cerebral ischemia using defective herpes simplex viral vectors. Ann N Y Acad Sci. 2001;939:340–57.
-
(2001)
Ann N Y Acad Sci
, vol.939
, pp. 340-357
-
-
Yenari, M.A.1
Dumas, T.C.2
Sapolsky, R.M.3
Steinberg, G.K.4
-
112
-
-
10744231759
-
Incidence and mechanisms of cerebral ischemia in early clinical head injury
-
PID: 14747747
-
Coles JP, Fryer TD, Smielewski P, Chatfield DA, Steiner LA, Johnston AJ, et al. Incidence and mechanisms of cerebral ischemia in early clinical head injury. J Cereb Blood Flow Metab. 2004;24(2):202–11.
-
(2004)
J Cereb Blood Flow Metab
, vol.24
, Issue.2
, pp. 202-211
-
-
Coles, J.P.1
Fryer, T.D.2
Smielewski, P.3
Chatfield, D.A.4
Steiner, L.A.5
Johnston, A.J.6
-
113
-
-
77956520638
-
Epidemiology and risk factors of cerebral ischemia and ischemic heart diseases: similarities and differences
-
PID: 21804773
-
Soler EP, Ruiz VC. Epidemiology and risk factors of cerebral ischemia and ischemic heart diseases: similarities and differences. Curr Cardiol Rev. 2010;6(3):138–49.
-
(2010)
Curr Cardiol Rev
, vol.6
, Issue.3
, pp. 138-149
-
-
Soler, E.P.1
Ruiz, V.C.2
-
115
-
-
0037315747
-
The impact of systemic infection on the progression of neurodegenerative disease
-
COI: 1:CAS:528:DC%2BD3sXot12itQ%3D%3D, PID: 12563281
-
Perry VH, Newman TA, Cunningham C. The impact of systemic infection on the progression of neurodegenerative disease. Nat Rev Neurosci. 2003;4(2):103–212.
-
(2003)
Nat Rev Neurosci
, vol.4
, Issue.2
, pp. 103-212
-
-
Perry, V.H.1
Newman, T.A.2
Cunningham, C.3
-
116
-
-
59349100950
-
Systemic infection and inflammation in acute CNS injury and chronic neurodegeneration: underlying mechanisms
-
COI: 1:CAS:528:DC%2BD1MXhsFKrtLo%3D, PID: 18706982
-
Teeling JL, Perry VH. Systemic infection and inflammation in acute CNS injury and chronic neurodegeneration: underlying mechanisms. Neuroscience. 2009;158(3):1062–73.
-
(2009)
Neuroscience
, vol.158
, Issue.3
, pp. 1062-1073
-
-
Teeling, J.L.1
Perry, V.H.2
-
117
-
-
0035078659
-
Neurodegenerative disorders and ischemic brain diseases
-
COI: 1:CAS:528:DC%2BD3MXivVGrsL0%3D, PID: 11321043
-
Mattson MP, Duan W, Pedersen WA, Culmsee C. Neurodegenerative disorders and ischemic brain diseases. Apoptosis. 2001;6(1–2):69–81.
-
(2001)
Apoptosis
, vol.6
, Issue.1-2
, pp. 69-81
-
-
Mattson, M.P.1
Duan, W.2
Pedersen, W.A.3
Culmsee, C.4
-
118
-
-
84931261067
-
Modern medical management of acute ischemic stroke
-
PID: 25114761
-
Goldstein LB. Modern medical management of acute ischemic stroke. Methodist Debakey Cardiovasc J. 2014;10(2):99–104.
-
(2014)
Methodist Debakey Cardiovasc J
, vol.10
, Issue.2
, pp. 99-104
-
-
Goldstein, L.B.1
-
119
-
-
0035942303
-
Clinical carotid endarterectomy decision making: noninvasive vascular imaging versus angiography
-
COI: 1:STN:280:DC%2BD3M3jtFCkuw%3D%3D, PID: 11320170
-
Johnston DCC, Goldstein LB. Clinical carotid endarterectomy decision making: noninvasive vascular imaging versus angiography. Neurology. 2001;56(8):1009–15.
-
(2001)
Neurology
, vol.56
, Issue.8
, pp. 1009-1015
-
-
Johnston, D.C.C.1
Goldstein, L.B.2
-
120
-
-
0037153037
-
Transient ischemic attack—proposal for a new definition
-
PID: 12444191
-
Albers GW, Caplan LR, Easton JD, Fayad PB, Mohr JP, Saver JL, et al. Transient ischemic attack—proposal for a new definition. N Engl J Med. 2002;347(21):1713–6.
-
(2002)
N Engl J Med
, vol.347
, Issue.21
, pp. 1713-1716
-
-
Albers, G.W.1
Caplan, L.R.2
Easton, J.D.3
Fayad, P.B.4
Mohr, J.P.5
Saver, J.L.6
-
121
-
-
42349095894
-
Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke
-
COI: 1:CAS:528:DC%2BD1cXkvVSrsLY%3D, PID: 18303253
-
Kidwell CS, Latour L, Saver JL, Alger JR, Starkman S, Duckwiler G, et al. Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke. Cerebrovasc Dis. 2008;25(4):338–43.
-
(2008)
Cerebrovasc Dis
, vol.25
, Issue.4
, pp. 338-343
-
-
Kidwell, C.S.1
Latour, L.2
Saver, J.L.3
Alger, J.R.4
Starkman, S.5
Duckwiler, G.6
-
122
-
-
49849089117
-
Early disruption of the blood–brain barrier after thrombolytic therapy predicts hemorrhage in patients with acute stroke
-
COI: 1:CAS:528:DC%2BD1cXos12iur4%3D, PID: 18556588
-
Kastrup A, Groschel K, Ringer TM, Redecker C, Cordesmeyer R, Witte OW, et al. Early disruption of the blood–brain barrier after thrombolytic therapy predicts hemorrhage in patients with acute stroke. Stroke. 2008;39(8):2385–7.
-
(2008)
Stroke
, vol.39
, Issue.8
, pp. 2385-2387
-
-
Kastrup, A.1
Groschel, K.2
Ringer, T.M.3
Redecker, C.4
Cordesmeyer, R.5
Witte, O.W.6
-
123
-
-
0034645547
-
Short-term prognosis after emergency department diagnosis of TIA
-
COI: 1:STN:280:DC%2BD3M%2Fos1aktg%3D%3D, PID: 11147987
-
Johnston SC, Gress DR, Browner WS, Sidney S. Short-term prognosis after emergency department diagnosis of TIA. JAMA. 2000;284(22):2901–6.
-
(2000)
JAMA
, vol.284
, Issue.22
, pp. 2901-2906
-
-
Johnston, S.C.1
Gress, D.R.2
Browner, W.S.3
Sidney, S.4
-
124
-
-
70349921190
-
The burden and management of TIA and stroke in government-funded healthcare programs
-
Gorelick PB. The burden and management of TIA and stroke in government-funded healthcare programs. Am J Manage Care. 2009;15(6 Suppl):S177–84.
-
(2009)
Am J Manage Care
, vol.15
, pp. 177-184
-
-
Gorelick, P.B.1
-
125
-
-
84875161421
-
Renal impairment reduces the efficacy of thrombolytic therapy in acute ischemic stroke
-
COI: 1:CAS:528:DC%2BC3sXjtFGisL8%3D, PID: 23428996
-
Power A, Epstein D, Cohen D, Bathula R, Devine J, Kar A, et al. Renal impairment reduces the efficacy of thrombolytic therapy in acute ischemic stroke. Cerebrovasc Dis. 2013;35(1):45–52.
-
(2013)
Cerebrovasc Dis
, vol.35
, Issue.1
, pp. 45-52
-
-
Power, A.1
Epstein, D.2
Cohen, D.3
Bathula, R.4
Devine, J.5
Kar, A.6
-
126
-
-
79951912520
-
Risk of thrombolytic therapy for acute ischemic stroke in patients with current malignancy
-
PID: 20598579
-
Masrur S, Abdullah AR, Smith EE, Hidalgo R, El-Ghandour A, Rordorf G, et al. Risk of thrombolytic therapy for acute ischemic stroke in patients with current malignancy. J Stroke Cerebrovasc Dis. 2011;20(2):124–30.
-
(2011)
J Stroke Cerebrovasc Dis
, vol.20
, Issue.2
, pp. 124-130
-
-
Masrur, S.1
Abdullah, A.R.2
Smith, E.E.3
Hidalgo, R.4
El-Ghandour, A.5
Rordorf, G.6
-
127
-
-
34547401424
-
Advancing stroke therapeutics through genetic understanding
-
COI: 1:CAS:528:DC%2BD2sXhtVSnsb%2FP, PID: 17630939
-
Ross OA, Worrall BB, Meschia JF. Advancing stroke therapeutics through genetic understanding. Curr Drug Targets. 2007;8(7):850–9.
-
(2007)
Curr Drug Targets
, vol.8
, Issue.7
, pp. 850-859
-
-
Ross, O.A.1
Worrall, B.B.2
Meschia, J.F.3
-
128
-
-
79960058709
-
Thrombolysis in acute ischaemic stroke: an update
-
PID: 23251746
-
Robinson T, Zaheer Z, Mistri AK. Thrombolysis in acute ischaemic stroke: an update. Ther Adv Chronic Dis. 2011;2(2):119–31.
-
(2011)
Ther Adv Chronic Dis
, vol.2
, Issue.2
, pp. 119-131
-
-
Robinson, T.1
Zaheer, Z.2
Mistri, A.K.3
-
129
-
-
84893713788
-
Nanoscale drug delivery systems and the blood–brain barrier
-
COI: 1:CAS:528:DC%2BC2cXhs12lsbzM, PID: 24550672
-
Alyautdin R, Khalin I, Nafeeza MI, Haron MH, Kuznetsov D. Nanoscale drug delivery systems and the blood–brain barrier. Int J Nanomedicine. 2014;9:795–811.
-
(2014)
Int J Nanomedicine
, vol.9
, pp. 795-811
-
-
Alyautdin, R.1
Khalin, I.2
Nafeeza, M.I.3
Haron, M.H.4
Kuznetsov, D.5
-
130
-
-
84859996647
-
Modern methods for delivery of drugs across the blood–brain barrier
-
COI: 1:CAS:528:DC%2BC38XlvFygtbc%3D, PID: 22154620
-
Chen Y, Liu L. Modern methods for delivery of drugs across the blood–brain barrier. Adv Drug Deliv Rev. 2012;64(7):640–65.
-
(2012)
Adv Drug Deliv Rev
, vol.64
, Issue.7
, pp. 640-665
-
-
Chen, Y.1
Liu, L.2
-
131
-
-
25844469583
-
Drug metabolism and pharmacokinetics, the blood–brain barrier, and central nervous system drug discovery
-
PID: 16489365
-
Alavijeh MS, Chishty M, Qaiser MZ, Palmer AM. Drug metabolism and pharmacokinetics, the blood–brain barrier, and central nervous system drug discovery. NeuroRx. 2005;2(4):554–71.
-
(2005)
NeuroRx
, vol.2
, Issue.4
, pp. 554-571
-
-
Alavijeh, M.S.1
Chishty, M.2
Qaiser, M.Z.3
Palmer, A.M.4
-
132
-
-
41149121206
-
Mechanical thrombectomy for acute ischemic stroke: final results of the multi MERCI trial
-
PID: 18309168
-
Smith WS, Sung G, Saver J, Budzik R, Duckwiler G, Liebeskind DS, et al. Mechanical thrombectomy for acute ischemic stroke: final results of the multi MERCI trial. Stroke. 2008;39:1205–12.
-
(2008)
Stroke
, vol.39
, pp. 1205-1212
-
-
Smith, W.S.1
Sung, G.2
Saver, J.3
Budzik, R.4
Duckwiler, G.5
Liebeskind, D.S.6
-
133
-
-
68249091754
-
The penumbra pivotal stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease
-
Penumbra Pivotal Stroke Trial Investigators. The penumbra pivotal stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease. Stroke. 2009;40:2761–8.
-
(2009)
Stroke
, vol.40
, pp. 2761-2768
-
-
Penumbra Pivotal Stroke Trial Investigators1
-
134
-
-
84888320235
-
Prospective, multicenter, single-arm study of mechanical thrombectomy using solitaire flow restoration in acute ischemic stroke
-
PID: 23908066
-
Pereira VM, Gralla J, Davalos A, Bonafé A, Castaño C, Chapot R, et al. Prospective, multicenter, single-arm study of mechanical thrombectomy using solitaire flow restoration in acute ischemic stroke. Stroke. 2013;44(10):2802–7.
-
(2013)
Stroke
, vol.44
, Issue.10
, pp. 2802-2807
-
-
Pereira, V.M.1
Gralla, J.2
Davalos, A.3
Bonafé, A.4
Castaño, C.5
Chapot, R.6
-
135
-
-
33845404703
-
Mechanical thrombectomy for acute ischemic stroke, thrombus–device interaction, efficiency, and complications in vivo
-
PID: 17053185
-
Gralla J, Schroth G, Remonda L, Nedeltchev K, Slotboom J, Brekenfeld C. Mechanical thrombectomy for acute ischemic stroke, thrombus–device interaction, efficiency, and complications in vivo. Stroke. 2006;37:3019–24.
-
(2006)
Stroke
, vol.37
, pp. 3019-3024
-
-
Gralla, J.1
Schroth, G.2
Remonda, L.3
Nedeltchev, K.4
Slotboom, J.5
Brekenfeld, C.6
-
137
-
-
77149151217
-
Sonothrombolysis in the management of acute ischemic stroke
-
PID: 20104930
-
Rubiera M, Alexandrov AV. Sonothrombolysis in the management of acute ischemic stroke. Am J Cardiovasc Drugs. 2010;10(1):5–10.
-
(2010)
Am J Cardiovasc Drugs
, vol.10
, Issue.1
, pp. 5-10
-
-
Rubiera, M.1
Alexandrov, A.V.2
-
139
-
-
85013816949
-
Transcranial sonothrombolysis using high-intensity focused ultrasound: impact of increasing output power on clot fragmentation
-
PID: 25512864
-
Ahadi G, Welch CS, Grimm MJ, Fisher DJ, Zadicario E, Ernstrom K, et al. Transcranial sonothrombolysis using high-intensity focused ultrasound: impact of increasing output power on clot fragmentation. J Ther Ultrasound. 2013;1:22.
-
(2013)
J Ther Ultrasound
, vol.1
, pp. 22
-
-
Ahadi, G.1
Welch, C.S.2
Grimm, M.J.3
Fisher, D.J.4
Zadicario, E.5
Ernstrom, K.6
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