Safety of tPA in stroke mimics and neuroimaging-negative cerebral ischemia

Neurology

Volumn 74, Issue 17, 2010, Pages 1340-1345

  Chernyshev, O Y ^a   Martin Schild, S ^b   Albright, K C ^c   Barreto, A ^a   Misra, V ^a   Acosta, I ^a   Grotta, J C ^a   Savitz, S I ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TISSUE PLASMINOGEN ACTIVATOR;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CONVERSION DISORDER; DRUG EFFICACY; DRUG SAFETY; FEMALE; FIBRINOLYTIC THERAPY; FOLLOW UP; HUMAN; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MIGRAINE; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; NEUROIMAGING; NEUROIMAGING NEGATIVE CEREBRAL ISCHEMIA; NEUROLOGIC DISEASE; PRIORITY JOURNAL; RANKIN SCALE; SEIZURE; STROKE MIMIC; STROKE MIMICS;

EID: 77951731600     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0b013e3181dad5a6     Document Type: Article

References (12)

1. D'Addesio JP. Should thrombolytic therapy be the first-line treatment for acute ischemic stroke? N Engl J Med 1998;338:762; author reply 762-763.
2. Hemmen TM, Meyer BC, McClean TL, Lyden PD. Identification of nonischemic stroke mimics among 411 code strokes at the University of California, San Diego, Stroke Center. J Stroke Cerebrovasc Dis 2008;17:23-25.
3. Saver JL. Time is brain: quantified. Stroke 2006;37:263-266.
4. Caplan LR, Mohr JP, Kistler JP, Koroshetz W. Should thrombolytic therapy be the first-line treatment for acute ischemic stroke? Thrombolysis: not a panacea for ischemic stroke. N Engl J Med 1997;337:1309-1310; discussion 1313.
5. Winkler DT, Fluri F, Fuhr P, et al. Thrombolysis in stroke mimics: frequency, clinical characteristics, and outcome. Stroke 2009;40:1522-1525.
6. Scott PA, Silbergleit R. Misdiagnosis of stroke in tissue plasminogen activator-treated patients: characteristics and outcomes. Ann Emerg Med 2003;42:611-618. (Pubitemid 37329015)
7. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995;333: 1581-1587.
8. Vroomen PC, Buddingh MK, Luijckx GJ, De Keyser J. The incidence of stroke mimics among stroke department admissions in relation to age group. J Stroke Cerebrovasc Dis 2008;17:418-422.
9. Alexandrov AV, Molina CA, Grotta JC, et al. Ultrasound-enhanced systemic thrombolysis for acute ischemic stroke. N Engl J Med 2004;351:2170-2178. (Pubitemid 39507629)
10. Uchino K, Massaro L, Hammer MD. Transient ischemic attack after tissue plasminogen activator: aborted stroke or unnecessary stroke therapy? Cerebrovasc Dis 2009;29: 57-61.
11. Oppenheim C, Stanescu R, Dormont D, et al. False-negative diffusion-weighted MR findings in acute ischemic stroke. AJNR Am J Neuroradiol 2000;21:1434-1440.
12. The GUSTO investigators. An international randomized trial comparing four thrombolytic strategies for acute myo-cardial infarction. N Engl J Med 1993;329:673-682.