메뉴 건너뛰기




Volumn 40, Issue 6, 2015, Pages 1321-1331

'Second-Generation' Mephedrone Analogs, 4-MEC and 4-MePPP, Differentially Affect Monoamine Transporter Function

Author keywords

[No Author keywords available]

Indexed keywords

4'-METHYL-ALPHA-PYRROLIDINOPROPIOPHENONE; 4-METHYLETHCATHINONE; AMPHETAMINE DERIVATIVE; DOPAMINE; DOPAMINE RECEPTOR STIMULATING AGENT; DOPAMINE TRANSPORTER; PROPIOPHENONE DERIVATIVE; PYRROLE DERIVATIVE; SEROTONIN; SEROTONIN RECEPTOR AFFECTING AGENT; SEROTONIN TRANSPORTER;

EID: 84939961743     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2014.325     Document Type: Article
Times cited : (80)

References (63)
  • 1
    • 84882602412 scopus 로고    scopus 로고
    • Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats
    • Aarde SM, Angrish D, Barlow DJ, Wright MJ Jr, Vandewater SA, Creehan KM et al (2013a). Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats. Addict Biol 18: 786-799.
    • (2013) Addict Biol , vol.18 , pp. 786-799
    • Aarde, S.M.1    Angrish, D.2    Barlow, D.J.3    Wright, M.J.4    Vandewater, S.A.5    Creehan, K.M.6
  • 2
    • 84878135503 scopus 로고    scopus 로고
    • The novel recreational drug 3,4-methylenedioxypyrovalerone (MDPV) is a potent psychomotor stimulant: Self-administration and locomotor activity in rats
    • Aarde SM, Huang PK, Creehan KM, Dickerson TJ, Taffe MA (2013b). The novel recreational drug 3,4-methylenedioxypyrovalerone (MDPV) is a potent psychomotor stimulant: self-administration and locomotor activity in rats. Neuropharmacology 71: 130-140.
    • (2013) Neuropharmacology , vol.71 , pp. 130-140
    • Aarde, S.M.1    Huang, P.K.2    Creehan, K.M.3    Dickerson, T.J.4    Taffe, M.A.5
  • 3
    • 0041821557 scopus 로고    scopus 로고
    • Ionic currents in the human serotonin transporter reveal inconsistencies in the alternating access hypothesis
    • Adams SV, DeFelice LJ (2003). Ionic currents in the human serotonin transporter reveal inconsistencies in the alternating access hypothesis. Biophys J 85: 1548-1559.
    • (2003) Biophys J , vol.85 , pp. 1548-1559
    • Adams, S.V.1    DeFelice, L.J.2
  • 4
    • 76249105122 scopus 로고    scopus 로고
    • Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter
    • Andersen J, Olsen L, Hansen KB, Taboureau O, Jorgensen FS, Jorgensen AM et al (2010). Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter. J Biol Chem 285: 2051-2063.
    • (2010) J Biol Chem , vol.285 , pp. 2051-2063
    • Andersen, J.1    Olsen, L.2    Hansen, K.B.3    Taboureau, O.4    Jorgensen, F.S.5    Jorgensen, A.M.6
  • 5
    • 84865146744 scopus 로고    scopus 로고
    • A chemical analysis examining the pharmacology of novel psychoactive substances freely available over the internet and their impact on public (ill)health. Legal highs or illegal highs?
    • Ayres TC, Bond JW (2012). A chemical analysis examining the pharmacology of novel psychoactive substances freely available over the internet and their impact on public (ill)health. Legal highs or illegal highs? BMJ Open 2: e000977.
    • (2012) BMJ Open , vol.2 , pp. e000977
    • Ayres, T.C.1    Bond, J.W.2
  • 6
    • 84858335179 scopus 로고    scopus 로고
    • The designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissue
    • Baumann MH, Ayestas MA Jr, Partilla JS, Sink JR, Shulgin AT, Daley PF et al (2012). The designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissue. Neuropsychopharmacology 37: 1192-1203.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 1192-1203
    • Baumann, M.H.1    Ayestas, M.A.2    Partilla, J.S.3    Sink, J.R.4    Shulgin, A.T.5    Daley, P.F.6
  • 7
    • 84900833796 scopus 로고    scopus 로고
    • Evidence for a role of transporter-mediated currents in the depletion of brain serotonin induced by serotonin transporter substrates
    • Baumann MH, Bulling S, Benaderet TS, Saha K, Ayestas MA, Partilla JS et al (2014). Evidence for a role of transporter-mediated currents in the depletion of brain serotonin induced by serotonin transporter substrates. Neuropsychopharmacology 39: 1355-1365.
    • (2014) Neuropsychopharmacology , vol.39 , pp. 1355-1365
    • Baumann, M.H.1    Bulling, S.2    Benaderet, T.S.3    Saha, K.4    Ayestas, M.A.5    Partilla, J.S.6
  • 8
    • 79953011168 scopus 로고    scopus 로고
    • In vivo effects of amphetamine analogs reveal evidence for serotonergic inhibition of mesolimbic dopamine transmission in the rat
    • Baumann MH, Clark RD, Woolverton WL, Wee S, Blough BE, Rothman RB (2011). In vivo effects of amphetamine analogs reveal evidence for serotonergic inhibition of mesolimbic dopamine transmission in the rat. J Pharmacol Exp Ther 337: 218-225.
    • (2011) J Pharmacol Exp Ther , vol.337 , pp. 218-225
    • Baumann, M.H.1    Clark, R.D.2    Woolverton, W.L.3    Wee, S.4    Blough, B.E.5    Rothman, R.B.6
  • 10
    • 84873742824 scopus 로고    scopus 로고
    • Powerful cocaine-like actions of 3,4-methylenedioxypyrovalerone (MDPV), a principal constituent of psychoactive 'bath salts' products
    • Baumann MH, Partilla JS, Lehner KR, Thorndike EB, Hoffman AF, Holy M et al (2013b). Powerful cocaine-like actions of 3,4-methylenedioxypyrovalerone (MDPV), a principal constituent of psychoactive 'bath salts' products. Neuropsychopharmacology 38: 552-562.
    • (2013) Neuropsychopharmacology , vol.38 , pp. 552-562
    • Baumann, M.H.1    Partilla, J.S.2    Lehner, K.R.3    Thorndike, E.B.4    Hoffman, A.F.5    Holy, M.6
  • 11
    • 84902513198 scopus 로고    scopus 로고
    • Hybrid dopamine uptake blocker-serotonin releaser ligands: A new twist on transporter-focused therapeutics
    • Blough BE, Landavazo A, Partilla JS, Baumann MH, Decker AM, Page KM et al (2014). Hybrid dopamine uptake blocker-serotonin releaser ligands: a new twist on transporter-focused therapeutics. ACS Med Chem Lett 5: 623-627.
    • (2014) ACS Med Chem Lett , vol.5 , pp. 623-627
    • Blough, B.E.1    Landavazo, A.2    Partilla, J.S.3    Baumann, M.H.4    Decker, A.M.5    Page, K.M.6
  • 12
    • 84891829217 scopus 로고    scopus 로고
    • Abuse-related and abuse-limiting effects of methcathinone and the synthetic "bath salts" cathinone analogs methylenedioxy-pyrovalerone (MDPV), methylone and mephedrone on intracranial self-stimulation in rats
    • Bonano JS, Glennon RA, De Felice LJ, Banks ML, Negus SS (2014). Abuse-related and abuse-limiting effects of methcathinone and the synthetic "bath salts" cathinone analogs methylenedioxy-pyrovalerone (MDPV), methylone and mephedrone on intracranial self-stimulation in rats. Psychopharmacology 231: 199-207.
    • (2014) Psychopharmacology , vol.231 , pp. 199-207
    • Bonano, J.S.1    Glennon, R.A.2    De Felice, L.J.3    Banks, M.L.4    Negus, S.S.5
  • 13
    • 80053383779 scopus 로고    scopus 로고
    • Analysis of NRG 'legal highs' in the UK: Identification and formation of novel cathinones
    • Brandt SD, Freeman S, Sumnall HR, Measham F, Cole J (2011). Analysis of NRG 'legal highs' in the UK: identification and formation of novel cathinones. Drug Test Anal 3: 569-575.
    • (2011) Drug Test Anal , vol.3 , pp. 569-575
    • Brandt, S.D.1    Freeman, S.2    Sumnall, H.R.3    Measham, F.4    Cole, J.5
  • 14
    • 84875206459 scopus 로고    scopus 로고
    • Bath salts components mephedrone and methylenedioxypyrovalerone (MDPV) act synergistically at the human dopamine transporter
    • Cameron KN, Kolanos R, Solis E Jr, Glennon RA, De Felice LJ (2013). Bath salts components mephedrone and methylenedioxypyrovalerone (MDPV) act synergistically at the human dopamine transporter. Br J Pharmacol 168: 1750-1757.
    • (2013) Br J Pharmacol , vol.168 , pp. 1750-1757
    • Cameron, K.N.1    Kolanos, R.2    Solis, E.3    Glennon, R.A.4    De Felice, L.J.5
  • 16
    • 68949158460 scopus 로고    scopus 로고
    • A randomized double-blind placebo-controlled study of the long-term efficacy and safety of diethylpropion in the treatment of obese subjects
    • Cercato C, Roizenblatt VA, Leanca CC, Segal A, Lopes Filho AP, Mancini MC et al (2009). A randomized double-blind placebo-controlled study of the long-term efficacy and safety of diethylpropion in the treatment of obese subjects. Int J Obes 33: 857-865.
    • (2009) Int J Obes , vol.33 , pp. 857-865
    • Cercato, C.1    Roizenblatt, V.A.2    Leanca, C.C.3    Segal, A.4    Lopes Filho, A.P.5    Mancini, M.C.6
  • 17
    • 79960626573 scopus 로고    scopus 로고
    • The pharmacology and toxicology of the synthetic cathinone mephedrone (4-methylmethcathinone)
    • Dargan PI, Sedefov R, Gallegos A, Wood DM (2011). The pharmacology and toxicology of the synthetic cathinone mephedrone (4-methylmethcathinone). Drug Test Anal 3: 454-463.
    • (2011) Drug Test Anal , vol.3 , pp. 454-463
    • Dargan, P.I.1    Sedefov, R.2    Gallegos, A.3    Wood, D.M.4
  • 18
    • 84894051965 scopus 로고    scopus 로고
    • Synthetic cathinones: Chemical phylogeny, physiology, and neuropharmacology
    • De Felice LJ, Glennon RA, Negus SS (2014). Synthetic cathinones: chemical phylogeny, physiology, and neuropharmacology. Life Sci 97: 20-26.
    • (2014) Life Sci , vol.97 , pp. 20-26
    • De Felice, L.J.1    Glennon, R.A.2    Negus, S.S.3
  • 21
    • 84873724416 scopus 로고    scopus 로고
    • In vivo effects of abused 'bath salt' constituent 3,4-methylene-dioxypyrovalerone (MDPV) in mice: Drug discrimination, thermoregulation, and locomotor activity
    • Fantegrossi WE, Gannon BM, Zimmerman SM, Rice KC (2013). In vivo effects of abused 'bath salt' constituent 3,4-methylene-dioxypyrovalerone (MDPV) in mice: drug discrimination, thermoregulation, and locomotor activity. Neuropsychopharmacology 38: 563-573.
    • (2013) Neuropsychopharmacology , vol.38 , pp. 563-573
    • Fantegrossi, W.E.1    Gannon, B.M.2    Zimmerman, S.M.3    Rice, K.C.4
  • 22
    • 84881553576 scopus 로고    scopus 로고
    • Locomotor stimulant and discriminative stimulus effects of 'bath salt' cathinones
    • Gatch MB, Taylor CM, Forster MJ (2013). Locomotor stimulant and discriminative stimulus effects of 'bath salt' cathinones. Behav Pharmacol 24: 437-447.
    • (2013) Behav Pharmacol , vol.24 , pp. 437-447
    • Gatch, M.B.1    Taylor, C.M.2    Forster, M.J.3
  • 23
    • 84876471495 scopus 로고    scopus 로고
    • Analysis of 4-MEC in biological and non-biological material- three case reports
    • Gil D, Adamowicz P, Skulska A, Tokarczyk B, Stanaszek R (2013). Analysis of 4-MEC in biological and non-biological material- three case reports. Forensic Sci Int 228: e11-e15.
    • (2013) Forensic Sci Int , vol.228 , pp. e11-e15
    • Gil, D.1    Adamowicz, P.2    Skulska, A.3    Tokarczyk, B.4    Stanaszek, R.5
  • 24
    • 43549094952 scopus 로고    scopus 로고
    • N,N-dimethyl-thioamphetamine and methylthioamphetamine, two non-neurotoxic substrates of 5-HT transporters, have scant in vitro efficacy for the induction of transporter-mediated 5-HT release and currents
    • Gobbi M, Funicello M, Gerstbrein K, Holy M, Moya PR, Sotomayor R et al (2008). N,N-dimethyl-thioamphetamine and methylthioamphetamine, two non-neurotoxic substrates of 5-HT transporters, have scant in vitro efficacy for the induction of transporter-mediated 5-HT release and currents. J Neurochem 105: 1770-1780.
    • (2008) J Neurochem , vol.105 , pp. 1770-1780
    • Gobbi, M.1    Funicello, M.2    Gerstbrein, K.3    Holy, M.4    Moya, P.R.5    Sotomayor, R.6
  • 25
    • 80054789464 scopus 로고    scopus 로고
    • 4-Methylmethcathinone (mephedrone): Neuropharmacological effects of a designer stimulant of abuse
    • Hadlock GC, Webb KM, McFadden LM, Chu PW, Ellis JD, Allen SC et al (2011). 4-Methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuse. J Pharmacol Exp Ther 339: 530-536.
    • (2011) J Pharmacol Exp Ther , vol.339 , pp. 530-536
    • Hadlock, G.C.1    Webb, K.M.2    McFadden, L.M.3    Chu, P.W.4    Ellis, J.D.5    Allen, S.C.6
  • 26
    • 84902549627 scopus 로고    scopus 로고
    • Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters
    • Hofmaier T, Luf A, Seddik A, Stockner T, Holy M, Freissmuth M et al (2014). Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters. Neurochem Int 73: 32-41.
    • (2014) Neurochem Int , vol.73 , pp. 32-41
    • Hofmaier, T.1    Luf, A.2    Seddik, A.3    Stockner, T.4    Holy, M.5    Freissmuth, M.6
  • 27
    • 79952588669 scopus 로고    scopus 로고
    • Assessing the performance of the MM/PBSA and MM/GBSA methods. 1. The accuracy of binding free energy calculations based on molecular dynamics simulations
    • Hou T, Wang J, Li Y, Wang W (2011). Assessing the performance of the MM/PBSA and MM/GBSA methods. 1. The accuracy of binding free energy calculations based on molecular dynamics simulations. J Chem Inf Model 51: 69-82.
    • (2011) J Chem Inf Model , vol.51 , pp. 69-82
    • Hou, T.1    Wang, J.2    Li, Y.3    Wang, W.4
  • 28
    • 0031552362 scopus 로고    scopus 로고
    • Development and validation of a genetic algorithm for flexible docking
    • Jones G, Willett P, Glen RC, Leach AR, Taylor R (1997). Development and validation of a genetic algorithm for flexible docking. J Mol Biol 267: 727-748.
    • (1997) J Mol Biol , vol.267 , pp. 727-748
    • Jones, G.1    Willett, P.2    Glen, R.C.3    Leach, A.R.4    Taylor, R.5
  • 29
    • 0029912748 scopus 로고    scopus 로고
    • Development and testing of the OPLS all-atom force field on conformational energetics and properties of organic liquids
    • Jorgensen WL, Maxwell DS, Tirado Rives J (1996). Development and testing of the OPLS all-atom force field on conformational energetics and properties of organic liquids. J Am Chem Soc 118: 11225-11236.
    • (1996) J Am Chem Soc , vol.118 , pp. 11225-11236
    • Jorgensen, W.L.1    Maxwell, D.S.2    Tirado Rives, J.3
  • 30
    • 80054792045 scopus 로고    scopus 로고
    • Mephedrone, compared with MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and 5-HT levels in nucleus accumbens of awake rats
    • Kehr J, Ichinose F, Yoshitake S, Goiny M, Sievertsson T, Nyberg F et al (2011). Mephedrone, compared with MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and 5-HT levels in nucleus accumbens of awake rats. Br J Pharmacol 164: 1949-1958.
    • (2011) Br J Pharmacol , vol.164 , pp. 1949-1958
    • Kehr, J.1    Ichinose, F.2    Yoshitake, S.3    Goiny, M.4    Sievertsson, T.5    Nyberg, F.6
  • 31
    • 84890693905 scopus 로고    scopus 로고
    • "Deconstruction" of the abused synthetic cathinone methylene-dioxypyrovalerone (MDPV) and an examination of effects at the human dopamine transporter
    • Kolanos R, Solis E Jr, Sakloth F, De Felice LJ, Glennon RA (2013). "Deconstruction" of the abused synthetic cathinone methylene-dioxypyrovalerone (MDPV) and an examination of effects at the human dopamine transporter. ACS Chem Neurosci 4: 1524-1529.
    • (2013) ACS Chem Neurosci , vol.4 , pp. 1524-1529
    • Kolanos, R.1    Solis, E.2    Sakloth, F.3    De Felice, L.J.4    Glennon, R.A.5
  • 33
    • 84888080590 scopus 로고    scopus 로고
    • The analytical investigation of synthetic street drugs containing cathinone analogs
    • Leffler AM, Smith PB, de Armas A, Dorman FL (2014). The analytical investigation of synthetic street drugs containing cathinone analogs. Forensic Sci Int 234: 50-56.
    • (2014) Forensic Sci Int , vol.234 , pp. 50-56
    • Leffler, A.M.1    Smith, P.B.2    De Armas, A.3    Dorman, F.L.4
  • 34
    • 84894055173 scopus 로고    scopus 로고
    • Emergence and properties of spice and bath salts: A medicinal chemistry perspective
    • Lewin AH, Seltzman HH, Carroll FI, Mascarella SW, Reddy PA (2014). Emergence and properties of spice and bath salts: a medicinal chemistry perspective. Life Sci 97: 9-19.
    • (2014) Life Sci , vol.97 , pp. 9-19
    • Lewin, A.H.1    Seltzman, H.H.2    Carroll, F.I.3    Mascarella, S.W.4    Reddy, P.A.5
  • 35
    • 84865424242 scopus 로고    scopus 로고
    • Comparative neuropharmacology of three psychostimulant cathinone derivatives: Butylone, mephedrone and methylone
    • Lopez-Arnau R, Martinez-Clemente J, Pubill D, Escubedo E, Camarasa J (2012). Comparative neuropharmacology of three psychostimulant cathinone derivatives: butylone, mephedrone and methylone. Br J Pharmacol 167: 407-420.
    • (2012) Br J Pharmacol , vol.167 , pp. 407-420
    • Lopez-Arnau, R.1    Martinez-Clemente, J.2    Pubill, D.3    Escubedo, E.4    Camarasa, J.5
  • 36
    • 84875250918 scopus 로고    scopus 로고
    • Analysis of synthetic cathinones commonly found in bath salts in human performance and postmortem toxicology: Method development, drug distribution and interpretation of results
    • Marinetti LJ, Antonides HM (2013). Analysis of synthetic cathinones commonly found in bath salts in human performance and postmortem toxicology: method development, drug distribution and interpretation of results. J Anal Toxicol 37: 135-146.
    • (2013) J Anal Toxicol , vol.37 , pp. 135-146
    • Marinetti, L.J.1    Antonides, H.M.2
  • 37
    • 84908505909 scopus 로고    scopus 로고
    • Pharmacology of novel synthetic stimulants structurally related to the "bath salts" constituent 3,4-methylenedioxypyrovalerone (MDPV)
    • Marusich JA, Antonazzo KR, Wiley JL, Blough BE, Partilla JS, Baumann MH (2014). Pharmacology of novel synthetic stimulants structurally related to the "bath salts" constituent 3,4-methylenedioxypyrovalerone (MDPV). Neuropharmacology 87: 206-213.
    • (2014) Neuropharmacology , vol.87 , pp. 206-213
    • Marusich, J.A.1    Antonazzo, K.R.2    Wiley, J.L.3    Blough, B.E.4    Partilla, J.S.5    Baumann, M.H.6
  • 38
    • 84867232376 scopus 로고    scopus 로고
    • Effects of synthetic cathinones contained in "bath salts" on motor behavior and a functional observational battery in mice
    • Marusich JA, Grant KR, Blough BE, Wiley JL (2012). Effects of synthetic cathinones contained in "bath salts" on motor behavior and a functional observational battery in mice. Neurotoxicology 33: 1305-1313.
    • (2012) Neurotoxicology , vol.33 , pp. 1305-1313
    • Marusich, J.A.1    Grant, K.R.2    Blough, B.E.3    Wiley, J.L.4
  • 39
    • 33144477907 scopus 로고    scopus 로고
    • 1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: A promising class of monoamine uptake inhibitors
    • Meltzer PC, Butler D, Deschamps JR, Madras BK (2006). 1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors. J Med Chem 49: 1420-1432.
    • (2006) J Med Chem , vol.49 , pp. 1420-1432
    • Meltzer, P.C.1    Butler, D.2    Deschamps, J.R.3    Madras, B.K.4
  • 40
    • 84887404259 scopus 로고    scopus 로고
    • X-ray structure of dopamine transporter elucidates antidepressant mechanism
    • Penmatsa A, Wang KH, Gouaux E (2013). X-ray structure of dopamine transporter elucidates antidepressant mechanism. Nature 503: 85-90.
    • (2013) Nature , vol.503 , pp. 85-90
    • Penmatsa, A.1    Wang, K.H.2    Gouaux, E.3
  • 41
    • 84904582405 scopus 로고    scopus 로고
    • Cathinones derivatives-related deaths as exemplified by two fatal cases involving methcathinone with 4-methylmethcathinone and 4-methylethcathinone
    • Rojek S, Klys M, Maciow-Glab M, Kula K, Strona M (2014). Cathinones derivatives-related deaths as exemplified by two fatal cases involving methcathinone with 4-methylmethcathinone and 4-methylethcathinone. Drug Test Anal 6: 770-777.
    • (2014) Drug Test Anal , vol.6 , pp. 770-777
    • Rojek, S.1    Klys, M.2    Maciow-Glab, M.3    Kula, K.4    Strona, M.5
  • 42
    • 84857759598 scopus 로고    scopus 로고
    • Here today, gone tomorrow...and back again? A review of herbal marijuana alternatives (K2, Spice), synthetic cathinones (bath salts), kratom, Salvia divinorum, methoxetamine, and piperazines
    • Rosenbaum CD, Carreiro SP, Babu KM (2012). Here today, gone tomorrow...and back again? A review of herbal marijuana alternatives (K2, Spice), synthetic cathinones (bath salts), kratom, Salvia divinorum, methoxetamine, and piperazines. J Med Toxicol 8: 15-32.
    • (2012) J Med Toxicol , vol.8 , pp. 15-32
    • Rosenbaum, C.D.1    Carreiro, S.P.2    Babu, K.M.3
  • 43
    • 0242576358 scopus 로고    scopus 로고
    • Monoamine transporters and psychostimulant drugs
    • Rothman RB, Baumann MH (2003). Monoamine transporters and psychostimulant drugs. Eur J Pharmacol 479: 23-40.
    • (2003) Eur J Pharmacol , vol.479 , pp. 23-40
    • Rothman, R.B.1    Baumann, M.H.2
  • 45
    • 0034119972 scopus 로고    scopus 로고
    • Transporter-mediated release: A superfusion study on human embryonic kidney cells stably expressing the human serotonin transporter
    • Scholze P, Zwach J, Kattinger A, Pifl C, Singer EA, Sitte HH (2000). Transporter-mediated release: a superfusion study on human embryonic kidney cells stably expressing the human serotonin transporter. J Pharmacol Exp Ther 293: 870-878.
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 870-878
    • Scholze, P.1    Zwach, J.2    Kattinger, A.3    Pifl, C.4    Singer, E.A.5    Sitte, H.H.6
  • 46
    • 84879758449 scopus 로고    scopus 로고
    • Probing the selectivity of monoamine transporter substrates by means of molecular modeling
    • Seddik A, Holy M, Weissensteiner R, Zdrazil B, Sitte HH, Ecker GF (2013). Probing the selectivity of monoamine transporter substrates by means of molecular modeling. Mol Inform 32: 409-413.
    • (2013) Mol Inform , vol.32 , pp. 409-413
    • Seddik, A.1    Holy, M.2    Weissensteiner, R.3    Zdrazil, B.4    Sitte, H.H.5    Ecker, G.F.6
  • 48
    • 84890111184 scopus 로고    scopus 로고
    • Monoamine transporter and receptor interaction profiles of a new series of designer cathinones
    • Simmler LD, Rickli A, Hoener MC, Liechti ME (2014). Monoamine transporter and receptor interaction profiles of a new series of designer cathinones. Neuropharmacology 79: 152-160.
    • (2014) Neuropharmacology , vol.79 , pp. 152-160
    • Simmler, L.D.1    Rickli, A.2    Hoener, M.C.3    Liechti, M.E.4
  • 49
    • 72849113289 scopus 로고    scopus 로고
    • The reverse operation of Na(+)/Cl(-)-coupled neurotransmitter transporters-why amphetamines take two to tango
    • Sitte HH, Freissmuth M (2010). The reverse operation of Na(+)/Cl(-)-coupled neurotransmitter transporters-why amphetamines take two to tango. J Neurochem 112: 340-355.
    • (2010) J Neurochem , vol.112 , pp. 340-355
    • Sitte, H.H.1    Freissmuth, M.2
  • 50
    • 0031846705 scopus 로고    scopus 로고
    • Carrier-mediated release, transport rates, and charge transfer induced by amphetamine, tyramine, and dopamine in mammalian cells transfected with the human dopamine transporter
    • Sitte HH, Huck S, Reither H, Boehm S, Singer EA, Pifl C (1998). Carrier-mediated release, transport rates, and charge transfer induced by amphetamine, tyramine, and dopamine in mammalian cells transfected with the human dopamine transporter. J Neurochem 71: 1289-1297.
    • (1998) J Neurochem , vol.71 , pp. 1289-1297
    • Sitte, H.H.1    Huck, S.2    Reither, H.3    Boehm, S.4    Singer, E.A.5    Pifl, C.6
  • 51
    • 0031036030 scopus 로고    scopus 로고
    • Multiple ionic conductances of the human dopamine transporter: The actions of dopamine and psychostimulants
    • Sonders MS, Zhu SJ, Zahniser NR, Kavanaugh MP, Amara SG (1997). Multiple ionic conductances of the human dopamine transporter: the actions of dopamine and psychostimulants. J Neurosci 17: 960-974.
    • (1997) J Neurosci , vol.17 , pp. 960-974
    • Sonders, M.S.1    Zhu, S.J.2    Zahniser, N.R.3    Kavanaugh, M.P.4    Amara, S.G.5
  • 52
    • 80051712042 scopus 로고    scopus 로고
    • Clinical experience with and analytical confirmation of "bath salts" and "legal highs" (synthetic cathinones) in the United States
    • Spiller HA, Ryan ML, Weston RG, Jansen J (2011). Clinical experience with and analytical confirmation of "bath salts" and "legal highs" (synthetic cathinones) in the United States. Clin Toxicol 49: 499-505.
    • (2011) Clin Toxicol , vol.49 , pp. 499-505
    • Spiller, H.A.1    Ryan, M.L.2    Weston, R.G.3    Jansen, J.4
  • 53
    • 0142165136 scopus 로고    scopus 로고
    • Metabolism of the new designer drug alpha-pyrrolidinopropiophenone (PPP) and the toxicological detection of PPP and 4′-methyl-alpha-pyrrolidino-propiophenone (MPPP) studied in rat urine using gas chromatography-mass spectrometry
    • Springer D, Fritschi G, Maurer HH (2003). Metabolism of the new designer drug alpha-pyrrolidinopropiophenone (PPP) and the toxicological detection of PPP and 4′-methyl-alpha-pyrrolidino-propiophenone (MPPP) studied in rat urine using gas chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 796: 253-266.
    • (2003) J Chromatogr B Analyt Technol Biomed Life Sci , vol.796 , pp. 253-266
    • Springer, D.1    Fritschi, G.2    Maurer, H.H.3
  • 54
    • 0037097028 scopus 로고    scopus 로고
    • Studies on the metabolism and toxicological detection of the new designer drug 4′-methyl-alpha-pyrrolidinopropiophenone in urine using gas chromatography-mass spectrometry
    • Springer D, Peters FT, Fritschi G, Maurer HH (2002). Studies on the metabolism and toxicological detection of the new designer drug 4′-methyl-alpha-pyrrolidinopropiophenone in urine using gas chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 773: 25-33.
    • (2002) J Chromatogr B Analyt Technol Biomed Life Sci , vol.773 , pp. 25-33
    • Springer, D.1    Peters, F.T.2    Fritschi, G.3    Maurer, H.H.4
  • 55
    • 78651366871 scopus 로고    scopus 로고
    • The ugly side of amphetamines: Short- and long-term toxicity of 3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy'), methamphetamine and D-amphetamine
    • Steinkellner T, Freissmuth M, Sitte HH, Montgomery T (2011). The ugly side of amphetamines: short- and long-term toxicity of 3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy'), methamphetamine and D-amphetamine. Biol Chem 392: 103-115.
    • (2011) Biol Chem , vol.392 , pp. 103-115
    • Steinkellner, T.1    Freissmuth, M.2    Sitte, H.H.3    Montgomery, T.4
  • 56
    • 0031565115 scopus 로고    scopus 로고
    • Pharmacological profile of antidepressants and related compounds at human monoamine transporters
    • Tatsumi M, Groshan K, Blakely RD, Richelson E (1997). Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur J Pharmacol 340: 249-258.
    • (1997) Eur J Pharmacol , vol.340 , pp. 249-258
    • Tatsumi, M.1    Groshan, K.2    Blakely, R.D.3    Richelson, E.4
  • 58
    • 84887403382 scopus 로고    scopus 로고
    • Structural basis for action by diverse antidepressants on biogenic amine transporters
    • Wang H, Goehring A, Wang KH, Penmatsa A, Ressler R, Gouaux E (2013). Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature 503: 141-145.
    • (2013) Nature , vol.503 , pp. 141-145
    • Wang, H.1    Goehring, A.2    Wang, K.H.3    Penmatsa, A.4    Ressler, R.5    Gouaux, E.6
  • 59
    • 84894430078 scopus 로고    scopus 로고
    • Potent rewarding and reinforcing effects of the synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV)
    • Watterson LR, Kufahl PR, Nemirovsky NE, Sewalia K, Grabenauer M, Thomas BF et al (2014). Potent rewarding and reinforcing effects of the synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV). Addict Biol 19: 165-174.
    • (2014) Addict Biol , vol.19 , pp. 165-174
    • Watterson, L.R.1    Kufahl, P.R.2    Nemirovsky, N.E.3    Sewalia, K.4    Grabenauer, M.5    Thomas, B.F.6
  • 60
    • 84901614648 scopus 로고    scopus 로고
    • Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins
    • Wilhelm BG, Mandad S, Truckenbrodt S, Krohnert K, Schafer C, Rammner B et al (2014). Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Science 344: 1023-1028.
    • (2014) Science , vol.344 , pp. 1023-1028
    • Wilhelm, B.G.1    Mandad, S.2    Truckenbrodt, S.3    Krohnert, K.4    Schafer, C.5    Rammner, B.6
  • 61
    • 84865640924 scopus 로고    scopus 로고
    • Effect of ambient temperature on the thermoregulatory and locomotor stimulant effects of 4-methylmethcathinone in Wistar and Sprague-Dawley rats
    • Wright MJ Jr, Angrish D, Aarde SM, Barlow DJ, Buczynski MW, Creehan KM et al (2012). Effect of ambient temperature on the thermoregulatory and locomotor stimulant effects of 4-methylmethcathinone in Wistar and Sprague-Dawley rats. PLoS One 7: e44652.
    • (2012) PLoS One , vol.7 , pp. e44652
    • Wright, M.J.1    Angrish, D.2    Aarde, S.M.3    Barlow, D.J.4    Buczynski, M.W.5    Creehan, K.M.6
  • 62
    • 0033757257 scopus 로고    scopus 로고
    • Uptake and release effects of diethylpropion and its metabolites with biogenic amine transporters
    • Yu H, Rothman RB, Dersch CM, Partilla JS, Rice KC (2000). Uptake and release effects of diethylpropion and its metabolites with biogenic amine transporters. Bioorg Med Chem 8: 2689-2692.
    • (2000) Bioorg Med Chem , vol.8 , pp. 2689-2692
    • Yu, H.1    Rothman, R.B.2    Dersch, C.M.3    Partilla, J.S.4    Rice, K.C.5
  • 63
    • 65649089433 scopus 로고    scopus 로고
    • Evidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinil
    • Zolkowska D, Jain R, Rothman RB, Partilla JS, Roth BL, Setola V et al (2009). Evidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinil. J Pharmacol Exp Ther 329: 738-746.
    • (2009) J Pharmacol Exp Ther , vol.329 , pp. 738-746
    • Zolkowska, D.1    Jain, R.2    Rothman, R.B.3    Partilla, J.S.4    Roth, B.L.5    Setola, V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.