메뉴 건너뛰기




Volumn 97, Issue 1, 2014, Pages 9-19

Emergence and properties of spice and bath salts: A medicinal chemistry perspective

Author keywords

5HT; Cathinone; CB1; CB2; DAT; JWH; NET; Releaser; SERT; TAAR1

Indexed keywords

5HT; CATHINONE; CB1; CB2; DAT; JWH; NET; RELEASER; SERT; TAAR1;

EID: 84894055173     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2013.09.026     Document Type: Review
Times cited : (66)

References (94)
  • 1
    • 79955928510 scopus 로고    scopus 로고
    • CP47497-C8 and JWH073, commonly found in 'Spice' herbal blends, are potent and efficacious CB1 cannabinoid receptor agonists
    • B.K. Atwood, D. Lee, A. Straiker, T.S. Widlanski, and K. Mackie CP47497-C8 and JWH073, commonly found in 'Spice' herbal blends, are potent and efficacious CB1 cannabinoid receptor agonists Eur J Pharmacol 659 2011 139 145
    • (2011) Eur J Pharmacol , vol.659 , pp. 139-145
    • Atwood, B.K.1    Lee, D.2    Straiker, A.3    Widlanski, T.S.4    Mackie, K.5
  • 2
    • 0019925799 scopus 로고
    • Enantiomeric α-aminopropiophenones (cathinone): Preparation and investigation
    • DOI 10.1021/jo00134a026
    • B.D. Berrang, A.H. Lewin, and F.I. Carroll Enantiomeric α-aminopropiophenones (cathinone): preparation and investigation J Org Chem 47 1982 2643 2647 (Pubitemid 12008344)
    • (1982) Journal of Organic Chemistry , vol.47 , Issue.13 , pp. 2643-2647
    • Berrang, B.D.1    Lewin, A.H.2    Carroll, F.I.3
  • 3
    • 79960003774 scopus 로고    scopus 로고
    • Phase I hydroxylated metabolites of the K2 synthetic cannabinoid JWH 018 Retain in vitro and in vivo cannabinoid receptor affinity and activity
    • L.K. Brents, E.E. Reichard, S.M. Zimmerman, J.H. Moran, W.E. Fantegrossi, and P.L. Prather Phase I hydroxylated metabolites of the K2 synthetic cannabinoid JWH 018 Retain in vitro and in vivo cannabinoid receptor affinity and activity PLoS One 6 2011 e21917
    • (2011) PLoS One , vol.6 , pp. 21917
    • Brents, L.K.1    Reichard, E.E.2    Zimmerman, S.M.3    Moran, J.H.4    Fantegrossi, W.E.5    Prather, P.L.6
  • 4
    • 84857372061 scopus 로고    scopus 로고
    • Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity
    • L.K. Brents, A. Gallus-Zawada, A. Radominska-Pandya, T. Vasiljevik, T.E. Prisinzano, and W.E. Fantegrossi et al. Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity Biochem Pharmacol 83 2012 952 961
    • (2012) Biochem Pharmacol , vol.83 , pp. 952-961
    • Brents, L.K.1    Gallus-Zawada, A.2    Radominska-Pandya, A.3    Vasiljevik, T.4    Prisinzano, T.E.5    Fantegrossi, W.E.6
  • 5
    • 84875206459 scopus 로고    scopus 로고
    • Bath salts components mephedrone and methylenedioxypyrovalerone (MDPV) act synergistically at the human dopamine transporter
    • K.N. Cameron, R. Kolanos, E. Solis Jr., R.A. Glennon, and L.J. De Felice Bath salts components mephedrone and methylenedioxypyrovalerone (MDPV) act synergistically at the human dopamine transporter Br J Pharmacol 168 2013 1750 1757
    • (2013) Br J Pharmacol , vol.168 , pp. 1750-1757
    • Cameron, K.N.1    Kolanos, R.2    Solis Jr., E.3    Glennon, R.A.4    De Felice, L.J.5
  • 7
    • 84867684839 scopus 로고    scopus 로고
    • Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: Identification of novel cannabinoid receptor ligands
    • K.C. Chimalakonda, K.A. Seely, S.M. Bratton, L.K. Brents, C.L. Moran, and G.W. Endres et al. Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: identification of novel cannabinoid receptor ligands Drug Metab Dispos 40 2012 2174 2184
    • (2012) Drug Metab Dispos , vol.40 , pp. 2174-2184
    • Chimalakonda, K.C.1    Seely, K.A.2    Bratton, S.M.3    Brents, L.K.4    Moran, C.L.5    Endres, G.W.6
  • 8
    • 80054872333 scopus 로고    scopus 로고
    • 3,4-methylenedioxypyrovalerone (MDPV): Chemistry, pharmacology and toxicology of a new designer drug of abuse marketed online
    • M. Coppola, and R. Mondola 3,4-methylenedioxypyrovalerone (MDPV): chemistry, pharmacology and toxicology of a new designer drug of abuse marketed online Toxicol Lett 208 2012 12 15
    • (2012) Toxicol Lett , vol.208 , pp. 12-15
    • Coppola, M.1    Mondola, R.2
  • 9
    • 84863102188 scopus 로고    scopus 로고
    • Phenazepam and cannabinomimetics sold as herbal highs in New Zealand
    • R.A. Couch, and H. Madhavaram Phenazepam and cannabinomimetics sold as herbal highs in New Zealand Drug Test Anal 4 2012 409 414
    • (2012) Drug Test Anal , vol.4 , pp. 409-414
    • Couch, R.A.1    Madhavaram, H.2
  • 10
  • 12
    • 80052488621 scopus 로고    scopus 로고
    • Sympathomemetic toxicity in a case of analytically confirmed recreational use of naphyrone (naphtylpyrovalerone)
    • A. Derungs, S. Schietzel, M.R. Meyer, H.H. Maurer, S. Krahenbuhl, and M.E. Liechti Sympathomemetic toxicity in a case of analytically confirmed recreational use of naphyrone (naphtylpyrovalerone) Clin Toxicol 49 2011 691 693
    • (2011) Clin Toxicol , vol.49 , pp. 691-693
    • Derungs, A.1    Schietzel, S.2    Meyer, M.R.3    Maurer, H.H.4    Krahenbuhl, S.5    Liechti, M.E.6
  • 13
    • 84872683749 scopus 로고    scopus 로고
    • Symptoms, toxicities, and analytical results for a patient after smoking herbs containing the novel synthetic cannabinoid MAM-2201
    • A. Derungs, A.E. Schwaninger, G. Mansella, R. Bingisser, T. Kraemer, and M.E. Liechti Symptoms, toxicities, and analytical results for a patient after smoking herbs containing the novel synthetic cannabinoid MAM-2201 Forensic Toxicol 31 2013 164 171
    • (2013) Forensic Toxicol , vol.31 , pp. 164-171
    • Derungs, A.1    Schwaninger, A.E.2    Mansella, G.3    Bingisser, R.4    Kraemer, T.5    Liechti, M.E.6
  • 14
    • 0027496896 scopus 로고
    • Methcathinone: A Russian designer amphetamine infiltrates the rural midwest
    • DOI 10.1016/S0196-0644(05)80419-6
    • T.S. Emerson, and J.E. Cisek Methcathinone: a Russian designer amphetamine infiltrates the rural midwest Ann Emerg Med 22 1993 1897 1903 (Pubitemid 23346166)
    • (1993) Annals of Emergency Medicine , vol.22 , Issue.12 , pp. 1897-1903
    • Emerson, T.S.1    Cisek, J.E.2
  • 15
    • 79955468228 scopus 로고    scopus 로고
    • Identification and characterization of JWH-122 used as new ingredient in "spice-like" herbal incenses
    • L. Ernst, H.-M. Schiebel, C. Theuring, R. Lindigkeit, and T. Beuerle Identification and characterization of JWH-122 used as new ingredient in "Spice-like" herbal incenses Forensic Sci Int 208 2011 e31 e35
    • (2011) Forensic Sci Int , vol.208
    • Ernst, L.1    Schiebel, H.-M.2    Theuring, C.3    Lindigkeit, R.4    Beuerle, T.5
  • 16
    • 84865614191 scopus 로고    scopus 로고
    • Synthetic cannabinoids in "spice-like" herbal blends: First appearance of JWH-307 and recurrence of JWH-018 on the German market
    • L. Ernst, K. Krüger, R. Lindigkeit, H.-M. Schiebel, and T. Beuerle Synthetic cannabinoids in "spice-like" herbal blends: first appearance of JWH-307 and recurrence of JWH-018 on the German market Forensic Sci Int 222 2012 216 222
    • (2012) Forensic Sci Int , vol.222 , pp. 216-222
    • Ernst, L.1    Krüger, K.2    Lindigkeit, R.3    Schiebel, H.-M.4    Beuerle, T.5
  • 17
    • 84855507862 scopus 로고    scopus 로고
    • Beyond THC: The new generation of cannabinoid designer drugs
    • L. Fattore, and W. Fratta Beyond THC: the new generation of cannabinoid designer drugs Front Behav Neurosci 5 2011 60
    • (2011) Front Behav Neurosci , vol.5 , pp. 60
    • Fattore, L.1    Fratta, W.2
  • 18
    • 74849084874 scopus 로고    scopus 로고
    • Indol-3-ylcycloalkyl ketones: Effects of N1 substituted indole side chain variations on CB(2) cannabinoid receptor activity
    • J.M. Frost, M.J. Dart, K.R. Tietje, T.R. Garrison, G.K. Grayson, and A.V. Daza et al. Indol-3-ylcycloalkyl ketones: effects of N1 substituted indole side chain variations on CB(2) cannabinoid receptor activity J Med Chem 53 2010 295 315
    • (2010) J Med Chem , vol.53 , pp. 295-315
    • Frost, J.M.1    Dart, M.J.2    Tietje, K.R.3    Garrison, T.R.4    Grayson, G.K.5    Daza, A.V.6
  • 20
    • 77953869937 scopus 로고    scopus 로고
    • An analysis of the 'legal high' mephedrone
    • S. Gibbons, and M. Zloh An analysis of the 'legal high' mephedrone Bioorg Med Chem Lett 20 2010 4135 4139
    • (2010) Bioorg Med Chem Lett , vol.20 , pp. 4135-4139
    • Gibbons, S.1    Zloh, M.2
  • 21
    • 0036207407 scopus 로고    scopus 로고
    • Effect of 1-(3,4-methylenedioxyphenyl)-2-aminopropane and its optical isomers in PMMA-trained rats
    • DOI 10.1016/S0091-3057(01)00770-5, PII S0091305701007705
    • R.A. Glennon, and R. Young Effect of 1-(3,4-methylenedioxyphenyl)-2- aminopropane and its optical isomers in PMMA-trained rats Pharmacol Biochem Behav 72 2002 307 311 (Pubitemid 34251340)
    • (2002) Pharmacology Biochemistry and Behavior , vol.72 , Issue.1-2 , pp. 307-311
    • Glennon, R.A.1    Young, R.2
  • 23
    • 0030898647 scopus 로고    scopus 로고
    • Initial characterization of PMMA as a discriminative stimulus
    • DOI 10.1016/S0091-3057(96)00306-1, PII S0091305796003061
    • R.A. Glennon, R. Young, M. Dukat, and Y. Cheng Initial characterization of PMMA as a discriminative stimulus Pharmacol Biochem Behav 57 1997 151 158 (Pubitemid 27261405)
    • (1997) Pharmacology Biochemistry and Behavior , vol.57 , Issue.1-2 , pp. 151-158
    • Glennon, R.A.1    Young, R.2    Dukat, M.3    Cheng, Y.4
  • 25
    • 84863437164 scopus 로고    scopus 로고
    • Analysis of synthetic cannabinoids using high-resolution mass spectrometry and mass defect filtering: Implications for nontargeted screening of designer drugs
    • M. Grabenauer, W.L. Krol, J.L. Wiley, and B.F. Thomas Analysis of synthetic cannabinoids using high-resolution mass spectrometry and mass defect filtering: implications for nontargeted screening of designer drugs Anal Chem 84 2012 5574 5581
    • (2012) Anal Chem , vol.84 , pp. 5574-5581
    • Grabenauer, M.1    Krol, W.L.2    Wiley, J.L.3    Thomas, B.F.4
  • 26
    • 84881550563 scopus 로고    scopus 로고
    • Identification of two cannabimimetic compounds WIN48098 and AM679 in illegal products
    • A. Gregori, F. Damiano, M. Bonavia, V. Mileo, F. Varani, and M. Monfreda Identification of two cannabimimetic compounds WIN48098 and AM679 in illegal products Sci Justice 53 2013 286 292
    • (2013) Sci Justice , vol.53 , pp. 286-292
    • Gregori, A.1    Damiano, F.2    Bonavia, M.3    Mileo, V.4    Varani, F.5    Monfreda, M.6
  • 27
    • 84873746662 scopus 로고    scopus 로고
    • The detection of the urinary metabolites of 1-[(5-fluoropentyl)-1H-indol- 3-yl]-(2-iodophenyl)methanone (AM-694), a high affinity cannabimimetic, by gas chromatography - Mass spectrometry
    • A. Grigoryev, P. Kavanagh, and A. Melnik The detection of the urinary metabolites of 1-[(5-fluoropentyl)-1H-indol-3-yl]-(2-iodophenyl)methanone (AM-694), a high affinity cannabimimetic, by gas chromatography - mass spectrometry Drug Test Anal 5 2013 110 115
    • (2013) Drug Test Anal , vol.5 , pp. 110-115
    • Grigoryev, A.1    Kavanagh, P.2    Melnik, A.3
  • 31
    • 0025636291 scopus 로고
    • Pharmacological properties of the stimulant khat
    • P. Kalix Pharmacological properties of the stimulant khat Pharmacol Ther 48 1990 397 416
    • (1990) Pharmacol Ther , vol.48 , pp. 397-416
    • Kalix, P.1
  • 32
    • 33746882802 scopus 로고    scopus 로고
    • Metabolism of the recently encountered designer drug, methylone, in humans and rats
    • DOI 10.1080/00498250600780191, PII J777T92213L50M70
    • H.T. Kamata, N. Shima, K. Zaitsu, T. Kamata, A. Miki, and M. Nishikawa et al. Metabolism of the recently encountered designer drug, methylone, in humans and rats Xenobiotica 36 2006 709 723 (Pubitemid 44195985)
    • (2006) Xenobiotica , vol.36 , Issue.8 , pp. 709-723
    • Kamata, H.T.1    Shima, N.2    Zaitsu, K.3    Kamata, T.4    Miki, A.5    Nishikawa, M.6    Katagi, M.7    Tsuchihashi, H.8
  • 33
    • 80053422684 scopus 로고    scopus 로고
    • GHB and synthetic cathinones: Clinical effects and potential consequences
    • L. Karila, and M. Reynaud GHB and synthetic cathinones: clinical effects and potential consequences Drug Test Anal 3 2011 552 559
    • (2011) Drug Test Anal , vol.3 , pp. 552-559
    • Karila, L.1    Reynaud, M.2
  • 34
    • 84882263643 scopus 로고    scopus 로고
    • UR-144 in products sold via the Internet: Identification of related compounds and characterization of pyrolysis products
    • P. Kavanagh, A. Grigoryev, S. Savchuk, I. Mikhura, and A. Formanovsky UR-144 in products sold via the Internet: identification of related compounds and characterization of pyrolysis products Drug Test Anal 5 2013 683 692
    • (2013) Drug Test Anal , vol.5 , pp. 683-692
    • Kavanagh, P.1    Grigoryev, A.2    Savchuk, S.3    Mikhura, I.4    Formanovsky, A.5
  • 35
    • 79960634938 scopus 로고    scopus 로고
    • Cathinone derivatives: A review of their chemistry, pharmacology and toxicology
    • J.P. Kelly Cathinone derivatives: a review of their chemistry, pharmacology and toxicology Drug Test Anal 3 2011 439 453
    • (2011) Drug Test Anal , vol.3 , pp. 439-453
    • Kelly, J.P.1
  • 36
    • 84872675032 scopus 로고    scopus 로고
    • Changes in the prevalence of synthetic cannabinoids and cathinone derivatives in Japan until early 2012
    • R. Kikura-Hanajiri, N. Uchiyama, M. Kawamura, and Y. Goda Changes in the prevalence of synthetic cannabinoids and cathinone derivatives in Japan until early 2012 Forensic Toxicol 31 2013 44 53
    • (2013) Forensic Toxicol , vol.31 , pp. 44-53
    • Kikura-Hanajiri, R.1    Uchiyama, N.2    Kawamura, M.3    Goda, Y.4
  • 37
    • 84863910773 scopus 로고    scopus 로고
    • Analysis of 30 synthetic cannabinoids in serum by liquid chromatography-electrospray ionization tandem mass spectrometry after liquid-liquid extraction
    • S. Kneisel, and V. Auwarter Analysis of 30 synthetic cannabinoids in serum by liquid chromatography-electrospray ionization tandem mass spectrometry after liquid-liquid extraction J Mass Spectrom 47 2012 825 835
    • (2012) J Mass Spectrom , vol.47 , pp. 825-835
    • Kneisel, S.1    Auwarter, V.2
  • 38
    • 84865715662 scopus 로고    scopus 로고
    • Identification of the cannabimimetic AM-1220 and its azepane isomer (N-methylazepan-3-yl)-3-(1-naphthoyl)indole in a research chemical and several herbal mixtures
    • S. Kneisel, P. Bisel, V. Brecht, S. Broecker, M. Müller, and V. Auwärter Identification of the cannabimimetic AM-1220 and its azepane isomer (N-methylazepan-3-yl)-3-(1-naphthoyl)indole in a research chemical and several herbal mixtures Forensic Toxicol 30 2012 126 134
    • (2012) Forensic Toxicol , vol.30 , pp. 126-134
    • Kneisel, S.1    Bisel, P.2    Brecht, V.3    Broecker, S.4    Müller, M.5    Auwärter, V.6
  • 39
    • 84857460137 scopus 로고    scopus 로고
    • Identification and structural characterization of the synthetic cannabinoid 3-(1-adamantoyl)-1-pentylindole as an additive in 'herbal incense'
    • S. Kneisel, F. Westphal, P. Bisel, V. Brecht, S. Broecker, and V. Auwarter Identification and structural characterization of the synthetic cannabinoid 3-(1-adamantoyl)-1-pentylindole as an additive in 'herbal incense' J Mass Spectrom 47 2012 195 200
    • (2012) J Mass Spectrom , vol.47 , pp. 195-200
    • Kneisel, S.1    Westphal, F.2    Bisel, P.3    Brecht, V.4    Broecker, S.5    Auwarter, V.6
  • 41
  • 42
    • 80655136953 scopus 로고    scopus 로고
    • Trace amine-associated receptor 1 is a stereoselective binding site for compounds in the amphetamine class
    • A.H. Lewin, G.M. Miller, and B.P. Gilmour Trace amine-associated receptor 1 is a stereoselective binding site for compounds in the amphetamine class Bioorg Med Chem 19 2011 7044 7048
    • (2011) Bioorg Med Chem , vol.19 , pp. 7044-7048
    • Lewin, A.H.1    Miller, G.M.2    Gilmour, B.P.3
  • 45
    • 0024405051 scopus 로고
    • Identification and quantification of p-hydroxyethylamphetamine as a novel metabolite of ethylamphetamine in rat by gas chromatography-mass spectrometry
    • Y. Makino, T. Higuchi, S. Ohta, and M. Hirobe Identification and quantification of p-hydroxyethylamphetamine as a novel metabolite of ethylamphetamine in rat by gas chromatography-mass specrometry Forensic Sci Int 41 1989 83 91 (Pubitemid 19144655)
    • (1989) Forensic Science International , vol.41 , Issue.1-2 , pp. 83-91
    • Makino, Y.1    Higuchi, T.2    Ohta, S.3    Hirobe, M.4
  • 46
    • 33144477907 scopus 로고    scopus 로고
    • 1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (pyrovalerone) analogues: A promising class of monoamine uptake inhibitors
    • DOI 10.1021/jm050797a
    • P.C. Meltzer, D. Butler, J.R. Deschamps, and B.K. Madras 1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (pyrovalerone) analogues: a promising class of monoamine uptake inhibitors J Med Chem 49 2006 1420 1432 (Pubitemid 43271895)
    • (2006) Journal of Medicinal Chemistry , vol.49 , Issue.4 , pp. 1420-1432
    • Meltzer, P.C.1    Butler, D.2    Deschamps, J.R.3    Madras, B.K.4
  • 47
    • 84862657058 scopus 로고    scopus 로고
    • Separation and structural characterization of the synthetic cannabinoids JWH-412 and 1-[(5-fluoropentyl)-1H-indol-3yl]-(4-methylnaphthalen-1-yl)methanone using GC-MS, NMR analysis and a flash chromatography system
    • B. Moosmann, S. Kneisel, U. Girreser, V. Brecht, F. Westphal, and V. Auwärter Separation and structural characterization of the synthetic cannabinoids JWH-412 and 1-[(5-fluoropentyl)-1H-indol-3yl]-(4-methylnaphthalen- 1-yl)methanone using GC-MS, NMR analysis and a flash chromatography system Forensic Sci Int 220 2012 e17 e22
    • (2012) Forensic Sci Int , vol.220
    • Moosmann, B.1    Kneisel, S.2    Girreser, U.3    Brecht, V.4    Westphal, F.5    Auwärter, V.6
  • 48
    • 79960613145 scopus 로고    scopus 로고
    • Identification and quantitation of a benzoylindole (2-methoxyphenyl)(1- pentyl-1H-indol-3-yl)methanone and a naphthoylindole 1-(5-fluoropentyl-1H-indol- 3-yl) (naphthalene-1-yl)methanone (AM-2201) found in illegal products obtained via the Internet and their cannabimimetic effects evaluated by in vitro [35S]GTPγS binding assays
    • J. Nakajima, M. Takahashi, R. Nonaka, T. Seto, J. Suzuki, and M. Yoshida et al. Identification and quantitation of a benzoylindole (2-methoxyphenyl)(1- pentyl-1H-indol-3-yl)methanone and a naphthoylindole 1-(5-fluoropentyl-1H-indol- 3-yl) (naphthalene-1-yl)methanone (AM-2201) found in illegal products obtained via the Internet and their cannabimimetic effects evaluated by in vitro [35S]GTPγS binding assays Forensic Toxicol 29 2011 132 141
    • (2011) Forensic Toxicol , vol.29 , pp. 132-141
    • Nakajima, J.1    Takahashi, M.2    Nonaka, R.3    Seto, T.4    Suzuki, J.5    Yoshida, M.6
  • 49
    • 79251633132 scopus 로고    scopus 로고
    • Identification and quantitation of cannabimimetic compound JWH-250 as an adulterant in products obtained via the Internet
    • J. Nakajima, M. Takahashi, T. Seto, and J. Suzuki Identification and quantitation of cannabimimetic compound JWH-250 as an adulterant in products obtained via the Internet Forensic Toxicol 29 2011 51 55
    • (2011) Forensic Toxicol , vol.29 , pp. 51-55
    • Nakajima, J.1    Takahashi, M.2    Seto, T.3    Suzuki, J.4
  • 50
    • 79960618509 scopus 로고    scopus 로고
    • Identification and quantitation of two benzoylindoles AM-694 and (4-methoxyphenyl)(1-pentyl-1H-indol-3-yl)methanone, and three cannabimimetic naphthoylindoles JWH-210, JWH-122, and JWH-019 as adulterants in illegal products obtained via the Internet
    • J.-I. Nakajima, M. Takahashi, T. Seto, C. Kanai, J. Suzuki, and M. Yoshida et al. Identification and quantitation of two benzoylindoles AM-694 and (4-methoxyphenyl)(1-pentyl-1H-indol-3-yl)methanone, and three cannabimimetic naphthoylindoles JWH-210, JWH-122, and JWH-019 as adulterants in illegal products obtained via the Internet Forensic Toxicol 29 2011 95 110
    • (2011) Forensic Toxicol , vol.29 , pp. 95-110
    • Nakajima, J.-I.1    Takahashi, M.2    Seto, T.3    Kanai, C.4    Suzuki, J.5    Yoshida, M.6
  • 51
    • 84858705044 scopus 로고    scopus 로고
    • Identification and quantitation of two new naphthoylindole drugs-of-abuse, (1-(5-hydroxypentyl)-1H-indol-3-yl) (naphthalen-1-yl)methanone (AM-2202) and (1-(4-pentenyl)- 1H-indol-3-yl (naphthalen-1-yl)methanone, with other synthetic cannabinoids in unregulated "herbal" products circulated in the Tokyo ar
    • J. Nakajima, M. Takahashi, T. Seto, M. Yoshida, C. Kanai, and J. Suzuki et al. Identification and quantitation of two new naphthoylindole drugs-of-abuse, (1-(5-hydroxypentyl)-1H-indol-3-yl) (naphthalen-1-yl)methanone (AM-2202) and (1-(4-pentenyl)- 1H-indol-3-yl (naphthalen-1-yl)methanone, with other synthetic cannabinoids in unregulated "herbal" products circulated in the Tokyo ar Forensic Toxicol 30 2012 33 44
    • (2012) Forensic Toxicol , vol.30 , pp. 33-44
    • Nakajima, J.1    Takahashi, M.2    Seto, T.3    Yoshida, M.4    Kanai, C.5    Suzuki, J.6
  • 52
    • 84872683811 scopus 로고    scopus 로고
    • Analysis of azepane isomers of AM-2233 and AM-1220, and detection of an inhibitor of fatty acid amide hydrolase [30-(aminocarbonyl)(1,10-biphenyl)-3-yl] -cyclohexylcarbamate (URB597) obtained as designer drugs in the Tokyo area
    • J. Nakajima, M. Takahashi, T. Seto, C. Kanai, J. Suzuki, and M. Yoshida et al. Analysis of azepane isomers of AM-2233 and AM-1220, and detection of an inhibitor of fatty acid amide hydrolase [30-(aminocarbonyl)(1,10-biphenyl)-3-yl] -cyclohexylcarbamate (URB597) obtained as designer drugs in the Tokyo area Forensic Toxicol 31 2013 76 85
    • (2013) Forensic Toxicol , vol.31 , pp. 76-85
    • Nakajima, J.1    Takahashi, M.2    Seto, T.3    Kanai, C.4    Suzuki, J.5    Yoshida, M.6
  • 53
    • 84877900784 scopus 로고    scopus 로고
    • UIT Cambridge Ltd. Cambridge, England
    • D. Nutt Drugs without the hot air 2012 UIT Cambridge Ltd. Cambridge, England 72 90
    • (2012) Drugs Without the Hot Air , pp. 72-90
    • Nutt, D.1
  • 54
    • 84893107080 scopus 로고    scopus 로고
    • ONDCP.(a.k.a. K2, Spice, bath salts, etc.). Office of National Drug Control Policy Fact Sheet: synthetic drugs [February:1]
    • ONDCP Synthetic drugs (a.k.a. K2, Spice, bath salts, etc.). Office of National Drug Control Policy Fact Sheet: synthetic drugs 2012 [February:1]
    • (2012) Synthetic Drugs
  • 55
    • 84879800033 scopus 로고    scopus 로고
    • Identification of a new synthetic cannabinoid in a herbal mixture: 1-butyl-3-(2-methoxybenzoyl)indole
    • Y. Park, C. Lee, H. Lee, J. Pyo, J. Jo, and J. Lee et al. Identification of a new synthetic cannabinoid in a herbal mixture: 1-butyl-3-(2-methoxybenzoyl) indole Forensic Toxicol 31 2013 187 196
    • (2013) Forensic Toxicol , vol.31 , pp. 187-196
    • Park, Y.1    Lee, C.2    Lee, H.3    Pyo, J.4    Jo, J.5    Lee, J.6
  • 56
  • 57
    • 84857800731 scopus 로고    scopus 로고
    • The toxicology of bath salts: A review of synthetic cathinones
    • J.M. Prosser, and L.S. Nelson The toxicology of bath salts: a review of synthetic cathinones J Med Toxicol 8 2012 33 42
    • (2012) J Med Toxicol , vol.8 , pp. 33-42
    • Prosser, J.M.1    Nelson, L.S.2
  • 58
    • 84876424034 scopus 로고    scopus 로고
    • Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors
    • M. Rajasekaran, L.K. Brents, L.N. Franks, J.H. Moran, and P.L. Prather Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors Toxicol Appl Pharmacol 269 2013 100 108
    • (2013) Toxicol Appl Pharmacol , vol.269 , pp. 100-108
    • Rajasekaran, M.1    Brents, L.K.2    Franks, L.N.3    Moran, J.H.4    Prather, P.L.5
  • 61
    • 67649201776 scopus 로고    scopus 로고
    • New designer drug alpha-pyrrolidinovalerophenone (PVP): Studies on its metabolism and toxicological detection in rat urine using gas chromatographic/mass spectrometric techniques
    • C. Sauer, F.T. Peters, C. Haas, M.R. Meyer, G. Fritschi, and H.H. Maurer New designer drug alpha-pyrrolidinovalerophenone (PVP): studies on its metabolism and toxicological detection in rat urine using gas chromatographic/mass spectrometric techniques J Mass Spectrom 44 2009 952 964
    • (2009) J Mass Spectrom , vol.44 , pp. 952-964
    • Sauer, C.1    Peters, F.T.2    Haas, C.3    Meyer, M.R.4    Fritschi, G.5    Maurer, H.H.6
  • 62
    • 79955466828 scopus 로고    scopus 로고
    • Acute poisoning involving the pyrrolidinophenone-type designer drug 4′-methyl-alpha-pyrrolidinohexanophenone (MPHP)
    • C. Sauer, K. Hoffmann, U. Schimmel, and F.T. Peters Acute poisoning involving the pyrrolidinophenone-type designer drug 4′-methyl-alpha- pyrrolidinohexanophenone (MPHP) Forensic Sci Int 208 2011 e20 e25
    • (2011) Forensic Sci Int , vol.208
    • Sauer, C.1    Hoffmann, K.2    Schimmel, U.3    Peters, F.T.4
  • 63
    • 84874332101 scopus 로고    scopus 로고
    • Acute kidney injury associated with synthetic cannabinoid use - Multiple states, 2012
    • M.D. Schwartz Acute kidney injury associated with synthetic cannabinoid use - multiple states, 2012 MMWR Morb Mortal Wkly Rep 62 2013 93 98
    • (2013) MMWR Morb Mortal Wkly Rep , vol.62 , pp. 93-98
    • Schwartz, M.D.1
  • 64
    • 84866989897 scopus 로고    scopus 로고
    • Spice drugs are more than harmless herbal blends: A review of the pharmacology and toxicology of synthetic cannabinoids
    • K.A. Seely, J. Lapoint, J.H. Moran, and L. Fattore Spice drugs are more than harmless herbal blends: a review of the pharmacology and toxicology of synthetic cannabinoids Prog Neuropsychopharmacol Biol Psychiatry 39 2012 234 243
    • (2012) Prog Neuropsychopharmacol Biol Psychiatry , vol.39 , pp. 234-243
    • Seely, K.A.1    Lapoint, J.2    Moran, J.H.3    Fattore, L.4
  • 65
    • 84865575642 scopus 로고    scopus 로고
    • Analysis of first and second generation legal highs for synthetic cannabinoids and synthetic stimulants by ultra-performance liquid chromatography and time of flight mass spectrometry
    • K.G. Shanks, T. Dahn, G. Behonick, and A. Terrell Analysis of first and second generation legal highs for synthetic cannabinoids and synthetic stimulants by ultra-performance liquid chromatography and time of flight mass spectrometry J Anal Toxicol 36 2012 360 371
    • (2012) J Anal Toxicol , vol.36 , pp. 360-371
    • Shanks, K.G.1    Dahn, T.2    Behonick, G.3    Terrell, A.4
  • 66
    • 84875593538 scopus 로고    scopus 로고
    • Identification and analytical properties of new synthetic cannabimimetics bearing 2,2,3,3-tetramethylcyclopropanecarbonyl moiety
    • V. Shevyrin, V. Melkozerov, A. Nevero, O. Eltsov, Y. Morzherin, and Y. Shafran Identification and analytical properties of new synthetic cannabimimetics bearing 2,2,3,3-tetramethylcyclopropanecarbonyl moiety Forensic Sci Int 226 2013 62 73
    • (2013) Forensic Sci Int , vol.226 , pp. 62-73
    • Shevyrin, V.1    Melkozerov, V.2    Nevero, A.3    Eltsov, O.4    Morzherin, Y.5    Shafran, Y.6
  • 68
    • 0142122818 scopus 로고    scopus 로고
    • Metabolism and toxicological detection of the new designer drug 3′,4′-methylenedioxy-α-pyrrolidinopropiophenone studied in urine using gas chromatography-mass spectrometry
    • DOI 10.1016/S1570-0232(03)00350-7
    • D. Springer, G. Fritschi, and H.H. Maurer Metabolism and toxicological detection of the new designer drug 3′,4′-methylenedioxy-alpha- pyrrolidinopropiophenone studied in urine using gas chromatography-mass spectrometry J Chromatogr B 793 2003 377 388 (Pubitemid 37271978)
    • (2003) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences , vol.793 , Issue.2 , pp. 377-388
    • Springer, D.1    Fritschi, G.2    Maurer, H.H.3
  • 69
    • 0142091104 scopus 로고    scopus 로고
    • Metabolism and toxicological detection of the new designer drug 4′-methoxy-α-pyrrolidinopropiophenone studied in rat urine using gas chromatography-mass spectrometry
    • DOI 10.1016/S1570-0232(03)00334-9
    • D. Springer, G. Fritschi, and H.H. Maurer Metabolism and toxicological detection of the new designer drug 4′-methoxy-alpha- pyrrolidinopropiophenone studied in rat urine using gas chromatography-mass spectrometry J Chromatogr B 793 2003 331 342 (Pubitemid 37271973)
    • (2003) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences , vol.793 , Issue.2 , pp. 331-342
    • Springer, D.1    Fritschi, G.2    Maurer, H.H.3
  • 70
    • 0142165136 scopus 로고    scopus 로고
    • Metabolism of the new designer drug α-pyrrolidinopropiophenone (PPP) and the toxicological detection of PPP and 4′-methyl-α- pyrrolidinopropiophenone (MPPP) studied in rat urine using gas chromatography-mass spectrometry
    • DOI 10.1016/j.jchromb.2003.07.008
    • D. Springer, G. Fritschi, and H.H. Maurer Metabolism of the new designer drug alpha-pyrrolidinopropiophenone (PPP) and the toxicological detection of PPP and 4′-methyll-alpha-pyrrolidinopropiophenone (MPPP) studied in rat urine using gas chromatography-mass spectrometry J Chromatogr B 796 2003 253 266 (Pubitemid 37329670)
    • (2003) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences , vol.796 , Issue.2 , pp. 253-266
    • Springer, D.1    Fritschi, G.2    Maurer, H.H.3
  • 71
    • 19944368433 scopus 로고    scopus 로고
    • Metabolism of designer drugs of abuse
    • DOI 10.2174/1389200054021825
    • R.F. Staack, and H.H. Maurer Metabolism of designer drugs of abuse Curr Drug Metab 6 2005 259 274 (Pubitemid 40753856)
    • (2005) Current Drug Metabolism , vol.6 , Issue.3 , pp. 259-274
    • Staack, R.F.1    Maurer, H.H.2
  • 72
    • 84872688151 scopus 로고    scopus 로고
    • Identification and quantitation of JWH-213, a cannabimimetic indole, as a designer drug in a herbal product
    • K. Takahashi, N. Uchiyama, T. Fukiwake, T. Hasegawa, M. Saijou, and Y. Motoki et al. Identification and quantitation of JWH-213, a cannabimimetic indole, as a designer drug in a herbal product Forensic Toxicol 31 2013 145 150
    • (2013) Forensic Toxicol , vol.31 , pp. 145-150
    • Takahashi, K.1    Uchiyama, N.2    Fukiwake, T.3    Hasegawa, T.4    Saijou, M.5    Motoki, Y.6
  • 73
    • 65349190511 scopus 로고    scopus 로고
    • Identification of a cannabinoid analog as a new type of designer drug in a herbal product
    • N. Uchiyama, R. Kikura-Hanajiri, N. Kawahara, Y. Haishima, and Y. Goda Identification of a cannabinoid analog as a new type of designer drug in a herbal product Chem Pharm Bull 57 2009 439 441
    • (2009) Chem Pharm Bull , vol.57 , pp. 439-441
    • Uchiyama, N.1    Kikura-Hanajiri, R.2    Kawahara, N.3    Haishima, Y.4    Goda, Y.5
  • 74
    • 79251632165 scopus 로고    scopus 로고
    • Identification and quantitation of two cannabimimetic phenylacetylindoles JWH-251 and JWH-250, and four cannabimimetic naphthoylindoles JWH-081, JWH-015, JWH-200, and JWH-073 as designer drugs in illegal products
    • N. Uchiyama, M. Kawamura, R. Kikura-Hanajiri, and Y. Goda Identification and quantitation of two cannabimimetic phenylacetylindoles JWH-251 and JWH-250, and four cannabimimetic naphthoylindoles JWH-081, JWH-015, JWH-200, and JWH-073 as designer drugs in illegal products Forensic Toxicol 29 2011 25 37
    • (2011) Forensic Toxicol , vol.29 , pp. 25-37
    • Uchiyama, N.1    Kawamura, M.2    Kikura-Hanajiri, R.3    Goda, Y.4
  • 75
    • 80052277722 scopus 로고    scopus 로고
    • Identification of a novel cannabimimetic phenylacetylindole, cannabipiperidiethanone, as a designer drug in a herbal product and its affinity for cannabinoid CB1 and CB2 receptors
    • N. Uchiyama, R. Kikura-Hanajiri, and Y. Goda Identification of a novel cannabimimetic phenylacetylindole, cannabipiperidiethanone, as a designer drug in a herbal product and its affinity for cannabinoid CB1 and CB2 receptors Chem Pharm Bull 59 2011 1203 1205
    • (2011) Chem Pharm Bull , vol.59 , pp. 1203-1205
    • Uchiyama, N.1    Kikura-Hanajiri, R.2    Goda, Y.3
  • 77
    • 84865779680 scopus 로고    scopus 로고
    • Identification of two new-type synthetic cannabinoids, N-(1-adamantyl)-1-pentyl-1H-indole-3-carboxamide (APICA) and N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide (APINACA), and detection of five synthetic cannabinoids, AM-1220, AM-2233, AM-1241, CB-13 (CRA-13), and AM-1248, as designer drugs in illegal products
    • N. Uchiyama, M. Kawamura, R. Kikura-Hanajiri, and Y. Goda Identification of two new-type synthetic cannabinoids, N-(1-adamantyl)-1-pentyl-1H-indole-3- carboxamide (APICA) and N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide (APINACA), and detection of five synthetic cannabinoids, AM-1220, AM-2233, AM-1241, CB-13 (CRA-13), and AM-1248, as designer drugs in illegal products Forensic Toxicol 30 2012 114 125
    • (2012) Forensic Toxicol , vol.30 , pp. 114-125
    • Uchiyama, N.1    Kawamura, M.2    Kikura-Hanajiri, R.3    Goda, Y.4
  • 78
    • 84875632307 scopus 로고    scopus 로고
    • URB-754: A new class of designer drug and 12 synthetic cannabinoids detected in illegal products
    • N. Uchiyama, M. Kawamura, R. Kikura-Hanajiri, and Y. Goda URB-754: a new class of designer drug and 12 synthetic cannabinoids detected in illegal products Forensic Sci Int 227 2013 21 32
    • (2013) Forensic Sci Int , vol.227 , pp. 21-32
    • Uchiyama, N.1    Kawamura, M.2    Kikura-Hanajiri, R.3    Goda, Y.4
  • 79
    • 84879793220 scopus 로고    scopus 로고
    • Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative a-PVT and an opioid receptor agonist AH-7921 identified in illegal products
    • N. Uchiyama, S. Matsuda, M. Kawamura, R. Kikura-Hanajiri, and Y. Goda Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative a-PVT and an opioid receptor agonist AH-7921 identified in illegal products Forensic Toxicol 31 2013 223 240
    • (2013) Forensic Toxicol , vol.31 , pp. 223-240
    • Uchiyama, N.1    Matsuda, S.2    Kawamura, M.3    Kikura-Hanajiri, R.4    Goda, Y.5
  • 80
    • 84872685862 scopus 로고    scopus 로고
    • New cannabimimetic indazole derivatives, N-(1-amino-3-methyl-1-xobutan-2- yl)-1-pentyl-1H-indazole-3-carboxamide (AB-PINACA) and N-(1-amino-3-methyl-1- oxobutan-2-yl)-1- (4-fluorobenzyl)-1H-indazole-3-carboxamide (AB-FUBINACA) identified as designer drugs in illegal products
    • N. Uchiyama, S. Matsuda, D. Wakana, R. Kikura-Hanajiri, and Y. Goda New cannabimimetic indazole derivatives, N-(1-amino-3-methyl-1-xobutan-2-yl)-1- pentyl-1H-indazole-3-carboxamide (AB-PINACA) and N-(1-amino-3-methyl-1-oxobutan- 2-yl)-1- (4-fluorobenzyl)-1H-indazole-3-carboxamide (AB-FUBINACA) identified as designer drugs in illegal products Forensic Toxicol 31 2013 93 100
    • (2013) Forensic Toxicol , vol.31 , pp. 93-100
    • Uchiyama, N.1    Matsuda, S.2    Wakana, D.3    Kikura-Hanajiri, R.4    Goda, Y.5
  • 82
    • 84870294814 scopus 로고    scopus 로고
    • Identification of 1-butyl-3-(1-(4-methyl)naphtoyl)indole detected for the first time in "herbal high" products on the Italian market
    • E. Valoti, E. Casagni, L. Dell'Acqua, M. Pallavicini, G. Roda, and C. Rusconi et al. Identification of 1-butyl-3-(1-(4-methyl)naphtoyl)indole detected for the first time in "herbal high" products on the Italian market Forensic Sci Int 223 2012 e42 e46
    • (2012) Forensic Sci Int , vol.223
    • Valoti, E.1    Casagni, E.2    Dell'Acqua, L.3    Pallavicini, M.4    Roda, G.5    Rusconi, C.6
  • 84
    • 84869211772 scopus 로고    scopus 로고
    • Inhalation exposure to smoke from synthetic "marijuana" produces potent cannabimimetic effects in mice
    • J.M. Wiebelhaus, J.L. Poklis, A. Poklis, R.E. Vann, A.H. Lichtman, and L.E. Wise Inhalation exposure to smoke from synthetic "marijuana" produces potent cannabimimetic effects in mice Drug Alcohol Depend 126 2012 316 323
    • (2012) Drug Alcohol Depend , vol.126 , pp. 316-323
    • Wiebelhaus, J.M.1    Poklis, J.L.2    Poklis, A.3    Vann, R.E.4    Lichtman, A.H.5    Wise, L.E.6
  • 85
    • 84861225909 scopus 로고    scopus 로고
    • 1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice
    • J.L. Wiley, J.A. Marusich, B.R. Martin, and J.W. Huffman 1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice Drug Alcohol Depend 123 2012 148 153
    • (2012) Drug Alcohol Depend , vol.123 , pp. 148-153
    • Wiley, J.L.1    Marusich, J.A.2    Martin, B.R.3    Huffman, J.W.4
  • 86
    • 84878586179 scopus 로고    scopus 로고
    • Synthetic cannabis: A comparison of patterns of use and effect profile with natural cannabis in a large global sample
    • A.R. Winstock, and M.J. Barratt Synthetic cannabis: a comparison of patterns of use and effect profile with natural cannabis in a large global sample Drug Alcohol Depend 131 2013 106 111
    • (2013) Drug Alcohol Depend , vol.131 , pp. 106-111
    • Winstock, A.R.1    Barratt, M.J.2
  • 87
    • 0042004342 scopus 로고
    • Physiologically active amines. III. Secondary and teriary beta-phenylpropylamines and beta-phenylisopropylamines
    • E.H. Woodruff, J.P. Lambooy, and W.E. Burt Physiologically active amines. III. Secondary and teriary beta-phenylpropylamines and beta- phenylisopropylamines J Am Chem Soc 40 1940 922 924
    • (1940) J Am Chem Soc , vol.40 , pp. 922-924
    • Woodruff, E.H.1    Lambooy, J.P.2    Burt, W.E.3
  • 88
    • 0021298177 scopus 로고
    • Preference in rhesus monkeys given a choice between cocaine and d, l-cathinone
    • W.L. Woolverton, and C.E. Johanson Preference in rhesus monkeys given a choice between cocaine and d, l-cathinone J Exp Anal Behav 41 1984 35 43
    • (1984) J Exp Anal Behav , vol.41 , pp. 35-43
    • Woolverton, W.L.1    Johanson, C.E.2
  • 89
    • 67649840643 scopus 로고    scopus 로고
    • A receptor mechanism for methamphetamine action in dopamine transporter regulation in brain
    • Z. Xie, and G.M. Miller A receptor mechanism for methamphetamine action in dopamine transporter regulation in brain J Pharmacol Exp Ther 330 2009 316 325
    • (2009) J Pharmacol Exp Ther , vol.330 , pp. 316-325
    • Xie, Z.1    Miller, G.M.2
  • 90
    • 0031797490 scopus 로고    scopus 로고
    • Discriminative stimulus effects of S(-)-methcathinone (CAT): A potent stimulant drug of abuse
    • DOI 10.1007/s002130050765
    • R. Young, and R.A. Glennon Discriminative stimulus effects of S(-)-methcathinone (CAT): a potent stimulant drug of abuse Psychopharmacology (Berl) 140 1998 250 256 (Pubitemid 28562444)
    • (1998) Psychopharmacology , vol.140 , Issue.3 , pp. 250-256
    • Young, R.1    Glennon, R.A.2
  • 91
    • 36148952529 scopus 로고    scopus 로고
    • MDMA (N-methyl-3,4-methylenedioxyamphetamine) and its stereoisomers: Similarities and differences in behavioral effects in an automated activity apparatus in mice
    • DOI 10.1016/j.pbb.2007.09.002, PII S009130570700281X
    • R. Young, and R.A. Glennon MDMA (N-methyl-3,4-methylenedioxyamphetamine) and its stereoisomers: similarities and differences in behavioral effects in an automated activity apparatus in mice Pharmacol Biochem Behav 88 2008 318 331 (Pubitemid 350116259)
    • (2008) Pharmacology Biochemistry and Behavior , vol.88 , Issue.3 , pp. 318-331
    • Young, R.1    Glennon, R.A.2
  • 92
    • 84865459635 scopus 로고    scopus 로고
    • Cardiotoxicity associated with the synthetic cannabinoid, K9, with laboratory confirmation
    • A.C. Young, E. Schwarz, G. Medina, A. Obafemi, S.-Y. Feng, and C. Kane et al. Cardiotoxicity associated with the synthetic cannabinoid, K9, with laboratory confirmation Am J Emerg Med 30 2012 1320.e5 1320.e7
    • (2012) Am J Emerg Med , vol.30
    • Young, A.C.1    Schwarz, E.2    Medina, G.3    Obafemi, A.4    Feng, S.-Y.5    Kane, C.6
  • 93
    • 0033757257 scopus 로고    scopus 로고
    • Uptake and release of diethylpropion and its metabolites with biogenic amine transporters
    • H. Yu, R.B. Rothman, C.M. Dersch, J.S. Partilla, and K.C. Rice Uptake and release of diethylpropion and its metabolites with biogenic amine transporters Bioorg Med Chem 8 2000 2689 2692
    • (2000) Bioorg Med Chem , vol.8 , pp. 2689-2692
    • Yu, H.1    Rothman, R.B.2    Dersch, C.M.3    Partilla, J.S.4    Rice, K.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.