Probing the selectivity of monoamine transporter substrates by means of molecular modeling

Molecular Informatics

Volumn 32, Issue 5-6, 2013, Pages 409-413

  Seddik, Amir ^a   Holy, Marion ^b   Weissensteiner, René ^a   Zdrazil, Barbara ^a   Sitte, Harald H ^b   Ecker, Gerhard F ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Common scaffold clustering; Docking; Dopamine transporter (DAT); Fenfluramine; Serotonin transporter (SERT); Substrate selectivity

Indexed keywords

AMINES; SCAFFOLDS;

CLUSTERINGS; COMMON SCAFFOLD CLUSTERING; DOCKING; DOPAMINE TRANSPORTER; DOPAMINE TRANSPORTERS; FENFLURAMINE; SEROTONIN TRANSPORTER; SEROTONIN TRANSPORTERS; SUBSTRATE SELECTIVITY;

SUBSTRATES;

METHYL GROUP; MONOAMINE DERIVATIVE; MONOAMINE TRANSPORTER; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; BIOLOGICAL ACTIVITY; CHIRALITY; HUMAN; HYDROGEN BOND; IC 50; LIPOPHILICITY; MOLECULAR DOCKING; MOLECULAR MODEL; MOLECULAR PROBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; RAT; SEQUENCE HOMOLOGY; STEREOSPECIFICITY; SYNAPTIC TRANSMISSION; SYNAPTOSOME;

EID: 84879758449     PISSN: 18681743     EISSN: 18681751     Source Type: Journal    
DOI: 10.1002/minf.201300013     Document Type: Article

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