Lack of the protein tyrosine phosphatase PTPN22 strengthens transplant tolerance to pancreatic islets in mice

Diabetologia

Volumn 58, Issue 6, 2015, Pages 1319-1328

  Fousteri, Georgia ^a,b,c   Jofra, Tatiana ^a,b,c   Di Fonte, Roberta ^a,b,c   Gagliani, Nicola ^a,b,c   Morsiani, Cristina ^a,b,c   Stabilini, Angela ^a,b,c   Battaglia, Manuela ^a,b,c  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Alma Mater Studiorum ^*  (Italy)

Author keywords

Alloreactivity; FOXP3; G CSF; Pancreatic islet transplantation; PTPN22; Rapamycin; Tr1 cells; Transplant tolerance; Treg cells

Indexed keywords

FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; GLUCOSE BLOOD LEVEL; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 22; PTPN22 PROTEIN, MOUSE;

ADOPTIVE TRANSFER; ANALYSIS; ANIMAL; AUTOIMMUNITY; BAGG ALBINO MOUSE; C3H MOUSE; C57BL MOUSE; CYTOLOGY; GENETICS; GLUCOSE BLOOD LEVEL; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MOUSE; PANCREAS ISLET; PANCREAS ISLET TRANSPLANTATION; PHYSIOLOGY; REGULATORY T LYMPHOCYTE; RISK FACTOR; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; TRANSPLANTATION TOLERANCE;

ADOPTIVE TRANSFER; ANIMALS; AUTOIMMUNITY; BLOOD GLUCOSE; FORKHEAD TRANSCRIPTION FACTORS; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 22; RISK FACTORS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; TRANSPLANTATION TOLERANCE;

EID: 84939937375     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-015-3540-9     Document Type: Article

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