The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals

Nature Immunology

Volumn 15, Issue 9, 2014, Pages 875-883

  Salmond, Robert J ^a   Brownlie, Rebecca J ^a   Morrison, Vicky L ^b   Zamoyska, Rose ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CYTOKINE; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 22; PEPTIDE; T LYMPHOCYTE RECEPTOR; LYMPHOCYTE ANTIGEN RECEPTOR; PTPN22 PROTEIN, MOUSE;

ALLELE; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; CELL ADHESION; CONJUGATION; CONTROLLED STUDY; DISEASE PREDISPOSITION; HOMEOSTASIS; LOSS OF FUNCTION MUTATION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTOPENIA; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; ANIMAL; AUTOIMMUNITY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION;

ALLELES; ANIMALS; ANTIGEN-PRESENTING CELLS; AUTOIMMUNITY; LYMPHOCYTE ACTIVATION; MICE; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 22; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 84906322377     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2958     Document Type: Article

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