A syndecan-4 binding peptide derived from laminin 5 uses a novel PKCε pathway to induce cross-linked actin network (CLAN) formation in human trabecular meshwork (HTM) cells

Experimental Cell Research

Volumn 327, Issue 2, 2014, Pages 171-182

  Filla, Mark S ^a   Clark, Ross ^b   Peters, Donna M ^a,b  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b Medical Science   (United States)

Author keywords

CLANs; Cytoskeleton; Laminin 5; Protein kinase C; Syndecan 4; Trabecular meshwork

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 2 MORPHOLINO 8 PHENYLCHROMONE; DEXAMETHASONE; HEPARIN; ISOENZYME; KALININ; LAMININ 1; LAMININ 5 DERIVED SYNDECAN 4 BINDING PEPTIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C ALPHA; PROTEIN KINASE C EPSILON; PROTEIN KINASE C GAMMA; PROTEIN KINASE C INHIBITOR; PROTEOHEPARAN SULFATE; SMALL INTERFERING RNA; SYNDECAN 1; SYNDECAN 2; SYNDECAN 3; SYNDECAN 4; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR; ACTIN; ANTIINFLAMMATORY AGENT; CELL ADHESION MOLECULE; CROSS LINKING REAGENT; MESSENGER RNA; PEPTIDE FRAGMENT; PROTEIN KINASE C;

ADOLESCENT; ADULT; AQUEOUS HUMOR OUTFLOW; ARTICLE; CELL CULTURE; CELL SPREADING; CELL STRAIN; CELL SURFACE; CONTROLLED STUDY; CROSS LINKED ACTIN NETWORK; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; INTRAOCULAR PRESSURE; NORMAL HUMAN; POLYMERASE CHAIN REACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; TRABECULAR MESHWORK; TRABECULAR MESHWORK CELL; WESTERN BLOTTING; ACTIN FILAMENT; CLANS; CYTOLOGY; CYTOSKELETON; DRUG ANTAGONISM; DRUG EFFECT; EYE DISEASE; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; METABOLISM; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CLANS; CYTOSKELETON; LAMININ 5; PROTEIN KINASE C; SYNDECAN-4; TRABECULAR MESHWORK;

ACTIN CYTOSKELETON; ACTINS; ADOLESCENT; ADULT; ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; CELL ADHESION MOLECULES; CELLS, CULTURED; CROSS-LINKING REAGENTS; DEXAMETHASONE; EYE DISEASES; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; PEPTIDE FRAGMENTS; PROTEIN KINASE C-EPSILON; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SYNDECAN-4; TRABECULAR MESHWORK;

EID: 84907664288     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2014.07.035     Document Type: Article

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