Biological properties of trabecular meshwork cells

Experimental Eye Research

Volumn 88, Issue 4, 2009, Pages 671-675

  Gasiorowski, Joshua Z ^a   Russell, Paul ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

biophysical properties; glucocorticoids; mechanical stretch; oxidation; phagocytosis; TGF ; tissue culture; trabecular meshwork cells

Indexed keywords

DEXAMETHASONE; TRANSFORMING GROWTH FACTOR BETA;

BIOPHYSICS; CELL CULTURE; GLAUCOMA; HUMAN; MECHANICAL STRESS; OXIDATIVE STRESS; PHAGOCYTOSIS; PRIORITY JOURNAL; REVIEW; TRABECULAR MESHWORK;

CELL CULTURE TECHNIQUES; DEXAMETHASONE; GLAUCOMA; GLUCOCORTICOIDS; HUMANS; MECHANOTRANSDUCTION, CELLULAR; MODELS, BIOLOGICAL; OXIDATIVE STRESS; PHAGOCYTOSIS; TRABECULAR MESHWORK; TRANSFORMING GROWTH FACTOR BETA;

EID: 64249121678     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2008.08.006     Document Type: Review

References (60)

1. Alvarado J., Murphy C., and Juster R. Trabecular meshwork cellularity in primary open-angle glaucoma and nonglaucomatous normals. Ophthalmology 91 (1984) 564-579
2. Bahler C.K., Howell K.G., Hann C.R., Fautsch M.P., and Johnson D.H. Prostaglandins increase trabecular meshwork outflow facility in cultured human anterior segments. Am. J. Ophthalmol. 145 (2008) 114-119
3. Bradley J.M., Kelley M.J., Rose A., and Acott T.S. Signaling pathways used in trabecular matrix metalloproteinase response to mechanical stretch. Investig. Ophthalmol. Vis. Sci. 44 (2003) 5174-5181
4. Bradley J.M., Kelley M.J., Zhu X., Anderssohn A.M., Alexander J.P., and Acott T.S. Effects of mechanical stretching on trabecular matrix metalloproteinases. Investig. Ophthalmol. Vis. Sci. 42 (2001) 1505-1513
5. Brody S., Anilkumar T., Liliensiek S., Last J.A., Murphy C.J., and Pandit A. Characterizing nanoscale topography of the aortic heart valve basement membrane for tissue engineering heart valve scaffold design. Tissue Eng. 12 (2006) 413-421
6. Buller C., Johnson D.H., and Tschumper R.C. Human trabecular meshwork phagocytosis. Observations in an organ culture system. Investig. Ophthalmol. Vis. Sci. 31 (1990) 2156-2163
7. Caballero M., Liton P.B., Epstein D.L., and Gonzalez P. Proteasome inhibition by chronic oxidative stress in human trabecular meshwork cells. Biochem. Biophys. Res. Commun. 308 (2003) 346-352
8. Chang I.L., Elner G., Yue Y.J., Cornicelli A., Kawa J.E., and Elner V.M. Expression of modified low-density lipoprotein receptors by trabecular meshwork cells. Curr. Eye Res. 10 (1991) 1101-1112
9. Chen C.C., Yeh L.K., Liu C.Y., Kao W.W., Samples J.R., Lin S.J., Hu F.R., and Wang I.J. Morphological differences between the trabecular meshworks of zebrafish and mammals. Curr. Eye Res. 33 (2008) 59-72
10. Clark A.F., Wilson K., McCartney M.D., Miggans S.T., Kunkle M., and Howe W. Glucocorticoid-induced formation of cross-linked actin networks in cultured human trabecular meshwork cells. Investig. Ophthalmol. Vis. Sci. 35 (1994) 281-294
11. Comes N., and Borras T. Functional delivery of synthetic naked siRNA to the human trabecular meshwork in perfused organ cultures. Mol. Vis. 13 (2007) 1363-1374
12. Diehl K.A., Foley J.D., Nealey P.F., and Murphy C.J. Nanoscale topography modulates corneal epithelial cell migration. J. Biomed. Mater. Res. A 75 (2005) 603-611
13. Ehrich D., Tripathi B., Tripathi R., and Duncker G. Effects of interleukin-1beta and dexamethasone on the expression of matrix metalloprotease mRNA by trabecular cells exposed to elevated hydrostatic pressure. Acta Ophthalmol. Scand. 83 (2005) 104-108
14. Flugel-Koch C., Ohlmann A., Fuchshofer R., Welge-Lussen U., and Tamm E.R. Thrombospondin-1 in the trabecular meshwork: localization in normal and glaucomatous eyes, and induction by TGF-beta1 and dexamethasone in vitro. Exp. Eye Res. 79 (2004) 649-663
15. Fuchshofer R., Yu A.H., Welge-Lussen U., and Tamm E.R. Bone morphogenetic protein-7 is an antagonist of transforming growth factor-beta2 in human trabecular meshwork cells. Investig. Ophthalmol. Vis. Sci. 48 (2007) 715-726
16. Hirata Y., Emori T., Eguchi S., Kanno K., Imai T., Ohta K., and Marumo F. Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells. J. Clin. Invest. 91 (1993) 1367-1373
17. Johnson D.H., Richardson T.M., and Epstein D.L. Trabecular meshwork recovery after phagocytic challenge. Curr. Eye Res. 8 (1989) 1121-1130
18. Johnson D.H., and Tschumper R.C. Human trabecular meshwork organ culture. A new method. Investig. Ophthalmol. Vis. Sci. 28 (1987) 945-953
19. Kee C., and Seo K. The effect of interleukin-1alpha on outflow facility in rat eyes. J. Glaucoma. 6 (1997) 246-249
20. Keller K.E., Bradley J.M., Kelley M.J., and Acott T.S. Effects of modifiers of glycosaminoglycan biosynthesis on outflow facility in perfusion culture. Investig. Ophthalmol. Vis. Sci. 49 (2008) 2495-2505
21. Keller K.E., Kelley M.J., and Acott T.S. Extracellular matrix gene alternative splicing by trabecular meshwork cells in response to mechanical stretching. Investig. Ophthalmol. Vis. Sci. 48 (2007) 1164-1172
22. Li G., Luna C., Liton P.B., Navarro I., Epstein D.L., and Gonzalez P. Sustained stress response after oxidative stress in trabecular meshwork cells. Mol. Vis. 13 (2007) 2282-2288
23. Liliensiek S.J., Campbell S., Nealey P.F., and Murphy C.J. The scale of substratum topographic features modulates proliferation of corneal epithelial cells and corneal fibroblasts. J. Biomed. Mater. Res. A 79 (2006) 185-192
24. Matsumoto Y., and Johnson D.H. Dexamethasone decreases phagocytosis by human trabecular meshwork cells in situ. Investig. Ophthalmol. Vis. Sci. 38 (1997) 1902-1907
25. Pang I.H., McCartney M.D., Steely H.T., and Clark A.F. Human ocular perfusion organ culture: a versatile ex vivo model for glaucoma research. J. Glaucoma 9 (2000) 468-479
26. Park C.H., and Latina M.A. Effects of gamma-interferon on human trabecular meshwork cell phagocytosis. Investig. Ophthalmol. Vis. Sci. 34 (1993) 2228-2236
27. Peters D.M., Herbert K., Biddick B., and Peterson J.A. Myocilin binding to Hep II domain of fibronectin inhibits cell spreading and incorporation of paxillin into focal adhesions. Exp. Cell Res. 303 (2005) 218-228
28. Polansky J.R., Fauss D.J., and Zimmerman C.C. Regulation of TIGR/MYOC gene expression in human trabecular meshwork cells. Eye 14 (2000) 503-514
29. Polansky J.R., Weinreb R.N., Baxter J.D., and Alvarado J. Human trabecular cells. I. Establishment in tissue culture and growth characteristics. Invest. Ophthalmol. Vis. Sci. 18 (1979) 1043-1049
30. Polansky J.R., Wood I.S., Maglio M.T., and Alvarado J.A. Trabecular meshwork cell culture in glaucoma research: evaluation of biological activity and structural properties of human trabecular cells in vitro. Ophthalmology 91 (1984) 580-595
31. Rhee D.J., Tamm E.R., and Russell P. Donor corneoscleral buttons: a new source of trabecular meshwork for research. Exp. Eye Res. 77 (2003) 749-756
32. Russell P., Gasiorowski J.Z., Nealy P.F., and Murphy C.J. Response of human trabecular meshwork cells to topographic cues on the nanoscale level. Investig. Ophthalmol. Vis. Sci. 49 (2008) 629-635
33. Samuelson D.A., and Gelatt K.N. Aqueous outflow in the beagle. I. Postnatal morphologic development of the iridocorneal angle: pectinate ligament and uveal trabecular meshwork. Curr. Eye Res. 3 (1984) 783-794
34. Santas A.J., Bahler C., Peterson J.A., Filla M.S., Kaufman P.L., Tamm E.R., Johnson D.H., and Peters D.M. Effect of heparin II domain of fibronectin on aqueous outflow in cultured anterior segments of human eyes. Investig. Ophthalmol. Vis. Sci. 44 (2003) 4796-4804
35. Schlunck G., Han H., Wecker T., Kampik D., Meyer-Ter-Vehn T., and Grehn F. Substrate rigidity modulates cell matrix interactions and protein expression in human trabecular meshwork cells. Investig. Ophthalmol. Vis. Sci. 49 (2008) 262-269
36. Scott P.A., Overby D.R., Freddo T.F., and Gong H. Comparative studies between species that do and do not exhibit the washout effect. Exp. Eye Res. 84 (2007) 435-443
37. Shen X., Koga T., Park B.C., SundarRaj N., and Yue B.Y. Rho GTPase and cAMP/protein kinase A signaling mediates myocilin-induced alterations in cultured human trabecular meshwork cells. J. Biol. Chem. 283 (2008) 603-612
38. Sherwood M.E., and Richardson T.M. Phagocytosis by trabecular meshwork cells: sequence of events in cats and monkeys. Exp. Eye Res. 46 (1988) 881-895
39. Smelser G.K., and Ozanics V. The development of the trabecular meshwork in primate eyes. Am. J. Ophthalmol. 1 (1971) 366-385
40. Stamer D.W., Roberts B.C., Epstein D.L., and Allingham R.R. Isolation of primary open-angle glaucomatous trabecular meshwork cells from whole eye tissue. Curr. Eye Res. 20 (2000) 347-350
41. Stamer W.D., Huang Y., Seftor R.E., Svensson S.S., Snyder R.W., and Regan J.W. Cultured human trabecular meshwork cells express functional alpha 2A adrenergic receptors. Investig. Ophthalmol. Vis. Sci. 37 (1996) 2426-2433
42. Stamer W.D., Seftor R.E., Snyder R.W., and Regan J.W. Cultured human trabecular meshwork cells express aquaporin-1 water channels. Curr. Eye Res. 14 (1995) 1095-1100
43. Tamm E.R., Russell P., Johnson D.H., and Piatigorsky J. Human and monkey trabecular meshwork accumulate alpha B-crystallin in response to heat shock and oxidative stress. Investig. Ophthalmol. Vis. Sci. 37 (1996) 2402-2413
44. Tamura M., Iwamoto Y., Nakatsuka K., and Yamanouchi U. Immunofluorescence studies of the cytoskeletal and contractile elements in cultured human trabecular cells. Jpn. J. Ophthalmol. 33 (1989) 95-102
45. Tripathi R.C., Li J., Chan W.F., and Tripathi B.J. Aqueous humor in glaucomatous eyes contains an increased level of TGF-beta 2. Exp. Eye Res. 59 (1994) 723-727
46. Tripathi R.C., and Tripathi B.J. Human trabecular endothelium, corneal endothelium, keratocytes, and scleral fibroblasts in primary cell culture. A comparative study of growth characteristics, morphology, and phagocytic activity by light and scanning electron microscopy. Exp. Eye Res. 35 (1982) 611-624
47. Tschumper R.C., and Johnson D.H. Trabecular meshwork cellularity. Differences between fellow eyes. Investig. Ophthalmol. Vis. Sci. 31 (1990) 1327-1331
48. Vittal V., Rose A., Gregory K.E., Kelley M.J., and Acott T.S. Changes in gene expression by trabecular meshwork cells in response to mechanical stretching. Investig. Ophthalmol. Vis. Sci. 46 (2005) 2857-2868
49. Wang N., Chintala S.K., Fini M.E., and Schuman J.S. Activation of a tissue-specific stress response in the aqueous outflow pathway of the eye defines the glaucoma disease phenotype. Nat. Med. 7 (2001) 304-309
50. Wang W.H., McNatt L.G., Pang I.H., Hellberg P.E., Fingert J.H., McCartney M.D., and Clark A.F. Increased expression of serum amyloid A in glaucoma and its effect on intraocular pressure. Investig. Ophthalmol. Vis. Sci. 49 (2008) 1916-1923
51. Weinreb R.N., Mitchell M.D., and Polansky J.R. Prostaglandin production by human trabecular cells: in vitro inhibition by dexamethasone. Investig. Ophthalmol. Vis. Sci. 24 (1983) 1541-1545
52. Welge-Lussen U., May C.A., Eichhorn M., Bloemendal H., and Lutjen-Drecoll E. AlphaB-crystallin in the trabecular meshwork is inducible by transforming growth factor-beta. Investig. Ophthalmol. Vis. Sci. 40 (1999) 2235-2241
53. Welge-Lussen U., May C.A., and Lutjen-Drecoll E. Induction of tissue transglutaminase in the trabecular meshwork by TGF-beta1 and TGF-beta2. Investig. Ophthalmol. Vis. Sci. 41 (2000) 2229-2238
54. Wentz-Hunter K., Kubota R., Shen X., and Yue B.Y. Extracellular myocilin affects activity of human trabecular meshwork cells. J. Cell. Physiol. 200 (2004) 45-52
55. Wordinger R.J., Agarwal R., Talati M., Fuller J., Lambert W., and Clark A.F. Expression of bone morphogenetic proteins (BMP), BMP receptors, and BMP associated proteins in human trabecular meshwork and optic nerve head cells and tissues. Mol. Vis. 8 (2002) 241-250
56. Wordinger R.J., and Clark A.F. Effects of glucocorticoids on the trabecular meshwork: towards a better understanding of glaucoma. Prog. Retin Eye Res. 18 (1999) 629-667
57. Wordinger R.J., Clark A.F., Agarwal R., Lambert W., McNatt L., Wilson S.E., Qu Z., and Fung B.K. Cultured human trabecular meshwork cells express functional growth factor receptors. Investig. Ophthalmol. Vis. Sci. 39 (1998) 1575-1589
58. Zhang X., Clark A.F., and Yorio T. Interactions of endothelin-1 with dexamethasone in primary cultured human trabecular meshwork cells. Investig. Ophthalmol. Vis. Sci. 44 (2003) 5301-5308
59. Zhang X., Ognibene C.M., Clark A.F., and Yorio T. Dexamethasone inhibition of trabecular meshwork cell phagocytosis and its modulation by glucocorticoid receptor beta. Exp. Eye Res. 84 (2007) 275-284
60. Zhou L., Fukuchi T., Kawa J.E., Higginbotham E.J., and Yue B.Y. Loss of cell-matrix cohesiveness after phagocytosis by trabecular meshwork cells. Investig. Ophthalmol. Vis. Sci. 36 (1995) 787-795