-
2
-
-
0033808223
-
The relationship between control of intraocular pressure and visual field deterioration. The AGIS Investigators
-
The Advanced Glaucoma Intervention Study (AGIS): 7
-
The Advanced Glaucoma Intervention Study (AGIS): 7. The relationship between control of intraocular pressure and visual field deterioration. The AGIS Investigators. Am J Ophthalmol. 2000;130:429-440.
-
(2000)
Am J Ophthalmol.
, vol.130
, pp. 429-440
-
-
-
3
-
-
0036822851
-
Reduction of intraocular pressure and glaucoma progression: Results from the Early Manifest Glaucoma Trial
-
Heijl A, Leske MC, Bengtsson B, Hyman L, Hussein M. Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial. Arch Ophthalmol. 2002;120:1268-1279.
-
(2002)
Arch Ophthalmol.
, vol.120
, pp. 1268-1279
-
-
Heijl, A.1
Leske, M.C.2
Bengtsson, B.3
Hyman, L.4
Hussein, M.5
-
4
-
-
0036269833
-
The Ocular Hypertension Treatment Study: A randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma
-
discussion 829-830
-
Kass MA, Heuer DK, Higginbotham EJ, et al. The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma. Arch Ophthalmol. 2002;120:701-713; discussion 829-830.
-
(2002)
Arch Ophthalmol.
, vol.120
, pp. 701-713
-
-
Kass, M.A.1
Heuer, D.K.2
Higginbotham, E.J.3
-
5
-
-
0037184443
-
Impact of intraocular pressure reduction on glaucoma progression
-
Lichter PR. Impact of intraocular pressure reduction on glaucoma progression. JAMA. 2002;288:2607-2608.
-
(2002)
JAMA.
, vol.288
, pp. 2607-2608
-
-
Lichter, P.R.1
-
6
-
-
64249161403
-
Structural changes of the trabecular meshwork in different kinds of glaucoma
-
Tektas OY, Lutjen-Drecoll E. Structural changes of the trabecular meshwork in different kinds of glaucoma. Exp Eye Res. 2009;88:769-775.
-
(2009)
Exp Eye Res.
, vol.88
, pp. 769-775
-
-
Tektas, O.Y.1
Lutjen-Drecoll, E.2
-
7
-
-
33644838936
-
TGFbeta2-induced changes in human trabecular meshwork: Implications for intraocular pressure
-
Fleenor DL, Shepard AR, Hellberg PE, Jacobson N, Pang IH, Clark AF. TGFbeta2-induced changes in human trabecular meshwork: implications for intraocular pressure. Invest Ophthalmol Vis Sci. 2006;47:226-234.
-
(2006)
Invest Ophthalmol Vis Sci.
, vol.47
, pp. 226-234
-
-
Fleenor, D.L.1
Shepard, A.R.2
Hellberg, P.E.3
Jacobson, N.4
Pang, I.H.5
Clark, A.F.6
-
9
-
-
77951230645
-
Adenoviral gene transfer of active human transforming growth factor-{beta}2 elevates intraocular pressure and reduces outflow facility in rodent eyes
-
Shepard AR, Millar JC, Pang IH, Jacobson N, Wang WH, Clark AF. Adenoviral gene transfer of active human transforming growth factor-{beta}2 elevates intraocular pressure and reduces outflow facility in rodent eyes. Invest Ophthalmol Vis Sci. 2010;51:2067-2076.
-
(2010)
Invest Ophthalmol Vis Sci.
, vol.51
, pp. 2067-2076
-
-
Shepard, A.R.1
Millar, J.C.2
Pang, I.H.3
Jacobson, N.4
Wang, W.H.5
Clark, A.F.6
-
10
-
-
34548444264
-
Bone morphogenetic proteins and their receptors in the eye
-
Wordinger RJ, Clark AF. Bone morphogenetic proteins and their receptors in the eye. Exp Biol Med (Maywood). 2007; 232:979-992.
-
(2007)
Exp Biol Med (Maywood).
, vol.232
, pp. 979-992
-
-
Wordinger, R.J.1
Clark, A.F.2
-
11
-
-
34047268565
-
Effects of TGFbeta2, BMP-4, and gremlin in the trabecular meshwork: Implications for glaucoma
-
Wordinger RJ, Fleenor DL, Hellberg PE, et al. Effects of TGFbeta2, BMP-4, and gremlin in the trabecular meshwork: implications for glaucoma. Invest Ophthalmol Vis Sci. 2007; 48:1191-1200.
-
(2007)
Invest Ophthalmol Vis Sci.
, vol.48
, pp. 1191-1200
-
-
Wordinger, R.J.1
Fleenor, D.L.2
Hellberg, P.E.3
-
13
-
-
40549098396
-
Increased expression of the WNT antagonist sFRP-1 in glaucoma elevates intraocular pressure
-
Wang WH, McNatt LG, Pang IH, et al. Increased expression of the WNT antagonist sFRP-1 in glaucoma elevates intraocular pressure. J Clin Invest. 2008;118:1056-1064.
-
(2008)
J Clin Invest.
, vol.118
, pp. 1056-1064
-
-
Wang, W.H.1
McNatt, L.G.2
Pang, I.H.3
-
14
-
-
12644269195
-
Purification and molecular cloning of a secreted, frizzled-related antagonist of Wnt action
-
Finch PW, He X, Kelley MJ, et al. Purification and molecular cloning of a secreted, frizzled-related antagonist of Wnt action. Proc Natl Acad Sci U S A. 1997;94:6770-6775.
-
(1997)
Proc Natl Acad Sci U S A.
, vol.94
, pp. 6770-6775
-
-
Finch, P.W.1
He, X.2
Kelley, M.J.3
-
15
-
-
0039174251
-
Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasic modulator of Wnt signaling
-
Uren A, Reichsman F, Anest V, et al. Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasic modulator of Wnt signaling. J Biol Chem. 2000;275:4374-4382.
-
(2000)
J Biol Chem.
, vol.275
, pp. 4374-4382
-
-
Uren, A.1
Reichsman, F.2
Anest, V.3
-
16
-
-
0033523005
-
Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling
-
Bafico A, Gazit A, Pramila T, Finch PW, Yaniv A, Aaronson SA. Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling. J Biol Chem. 1999;274: 16180-16187.
-
(1999)
J Biol Chem.
, vol.274
, pp. 16180-16187
-
-
Bafico, A.1
Gazit, A.2
Pramila, T.3
Finch, P.W.4
Yaniv, A.5
Aaronson, S.A.6
-
17
-
-
8444251784
-
The Wnt signaling pathway in development and disease
-
Logan CY, Nusse R. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol. 2004;20:781-810.
-
(2004)
Annu Rev Cell Dev Biol.
, vol.20
, pp. 781-810
-
-
Logan, C.Y.1
Nusse, R.2
-
18
-
-
67649470380
-
Proximal events in Wnt signal transduction
-
Angers S, Moon RT. Proximal events in Wnt signal transduction. Nat Rev Mol Cell Biol. 2009;10:468-477.
-
(2009)
Nat Rev Mol Cell Biol.
, vol.10
, pp. 468-477
-
-
Angers, S.1
Moon, R.T.2
-
19
-
-
70449115555
-
Regulation of convergence and extension movements during vertebrate gastrulation by the Wnt/PCP pathway
-
Roszko I, Sawada A, Solnica-Krezel L. Regulation of convergence and extension movements during vertebrate gastrulation by the Wnt/PCP pathway. Semin Cell Dev Biol. 2009;20: 986-997.
-
(2009)
Semin Cell Dev Biol.
, vol.20
, pp. 986-997
-
-
Roszko, I.1
Sawada, A.2
Solnica-Krezel, L.3
-
20
-
-
67650230896
-
Wnt/beta-catenin signaling: Components, mechanisms, and diseases
-
MacDonald BT, Tamai K, He X. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell. 2009;17:9-26.
-
(2009)
Dev Cell.
, vol.17
, pp. 9-26
-
-
McDonald, B.T.1
Tamai, K.2
He, X.3
-
21
-
-
3142688966
-
Role of lysophospholipid growth factors in the modulation of aqueous humor outflow facility
-
Mettu PS, Deng PF, Misra UK, Gawdi G, Epstein DL, Rao PV. Role of lysophospholipid growth factors in the modulation of aqueous humor outflow facility. Invest Ophthalmol Vis Sci. 2004;45:2263-2271.
-
(2004)
Invest Ophthalmol Vis Sci.
, vol.45
, pp. 2263-2271
-
-
Mettu, P.S.1
Deng, P.F.2
Misra, U.K.3
Gawdi, G.4
Epstein, D.L.5
Rao, P.V.6
-
22
-
-
0037329040
-
Aging of stromal-derived human breast fibroblasts might contribute to breast cancer progression
-
Martens JW, Sieuwerts AM, Bolt-deVries J, et al. Aging of stromal-derived human breast fibroblasts might contribute to breast cancer progression. Thromb Haemost. 2003;89:393-404.
-
(2003)
Thromb Haemost.
, vol.89
, pp. 393-404
-
-
Martens, J.W.1
Sieuwerts, A.M.2
Bolt-deVries, J.3
-
23
-
-
33644805812
-
Noninvasive measurement of rodent intraocular pressure with a rebound tonometer
-
Wang WH, Millar JC, Pang IH, Wax MB, Clark AF. Noninvasive measurement of rodent intraocular pressure with a rebound tonometer. Invest Ophthalmol Vis Sci. 2005;46:4617-4621.
-
(2005)
Invest Ophthalmol Vis Sci.
, vol.46
, pp. 4617-4621
-
-
Wang, W.H.1
Millar, J.C.2
Pang, I.H.3
Wax, M.B.4
Clark, A.F.5
-
24
-
-
0028123512
-
Preliminary characterization of a transformed cell strain derived from human trabecular meshwork
-
Pang IH, Shade DL, Clark AF, Steely HT, DeSantis L. Preliminary characterization of a transformed cell strain derived from human trabecular meshwork. Curr Eye Res. 1994;13:51-63.
-
(1994)
Curr Eye Res.
, vol.13
, pp. 51-63
-
-
Pang, I.H.1
Shade, D.L.2
Clark, A.F.3
Steely, H.T.4
DeSantis, L.5
-
25
-
-
18244389736
-
Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/betacatenin signaling is activated in human colon tumors
-
Yan D, Wiesmann M, Rohan M, et al. Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/betacatenin signaling is activated in human colon tumors. Proc Natl Acad Sci U S A. 2001;98:14973-14978.
-
(2001)
Proc Natl Acad Sci U S A.
, vol.98
, pp. 14973-14978
-
-
Yan, D.1
Wiesmann, M.2
Rohan, M.3
-
26
-
-
0036149985
-
Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors
-
Lustig B, Jerchow B, Sachs M, et al. Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors. Mol Cell Biol. 2002;22:1184-1193.
-
(2002)
Mol Cell Biol.
, vol.22
, pp. 1184-1193
-
-
Lustig, B.1
Jerchow, B.2
Sachs, M.3
-
27
-
-
0036148208
-
Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
-
Jho EH, Zhang T, Domon C, Joo CK, Freund JN, Costantini F. Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol Cell Biol. 2002;22:1172-1183.
-
(2002)
Mol Cell Biol.
, vol.22
, pp. 1172-1183
-
-
Jho, E.H.1
Zhang, T.2
Domon, C.3
Joo, C.K.4
Freund, J.N.5
Costantini, F.6
-
28
-
-
12844266797
-
Wnt-3a-dependent cell motility involves RhoA activation and is specifically regulated by dishevelled-2
-
Endo Y, Wolf V, Muraiso K, et al. Wnt-3a-dependent cell motility involves RhoA activation and is specifically regulated by dishevelled-2. J Biol Chem. 2005;280:777-786.
-
(2005)
J Biol Chem.
, vol.280
, pp. 777-786
-
-
Endo, Y.1
Wolf, V.2
Muraiso, K.3
-
29
-
-
0035066006
-
Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632
-
Rao PV, Deng PF, Kumar J, Epstein DL. Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632. Invest Ophthalmol Vis Sci. 2001;42:1029-1037.
-
(2001)
Invest Ophthalmol Vis Sci.
, vol.42
, pp. 1029-1037
-
-
Rao, P.V.1
Deng, P.F.2
Kumar, J.3
Epstein, D.L.4
-
30
-
-
0035164065
-
Effects of rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility
-
Honjo M, Tanihara H, Inatani M, et al. Effects of rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility. Invest Ophthalmol Vis Sci. 2001;42:137-144.
-
(2001)
Invest Ophthalmol Vis Sci.
, vol.42
, pp. 137-144
-
-
Honjo, M.1
Tanihara, H.2
Inatani, M.3
-
31
-
-
38349075260
-
Effect of immunomodulation with anti-CD40L antibody on adenoviralmediated transgene expression in mouse anterior segment
-
Millar JC, Pang IH, Wang WH, Wang Y, Clark AF. Effect of immunomodulation with anti-CD40L antibody on adenoviralmediated transgene expression in mouse anterior segment. Mol Vis. 2008;14:10-19.
-
(2008)
Mol Vis.
, vol.14
, pp. 10-19
-
-
Millar, J.C.1
Pang, I.H.2
Wang, W.H.3
Wang, Y.4
Clark, A.F.5
-
32
-
-
0035902050
-
LDL-receptor-related protein 6 is a receptor for Dickkopf proteins
-
Mao B, Wu W, Li Y, et al. LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature. 2001;411:321-325.
-
(2001)
Nature.
, vol.411
, pp. 321-325
-
-
Mao, B.1
Wu, W.2
Li, Y.3
-
33
-
-
0142254155
-
A transcriptional response to Wnt protein in human embryonic carcinoma cells
-
Willert J, Epping M, Pollack JR, Brown PO, Nusse R. A transcriptional response to Wnt protein in human embryonic carcinoma cells. BMC Dev Biol. 2002;2:8.
-
(2002)
BMC Dev Biol.
, vol.2
, pp. 8
-
-
Willert, J.1
Epping, M.2
Pollack, J.R.3
Brown, P.O.4
Nusse, R.5
-
34
-
-
0037093072
-
Oncogenic beta-catenin is required for bone morphogenetic protein 4 expression in human cancer cells
-
Kim JS, Crooks H, Dracheva T, et al. Oncogenic beta-catenin is required for bone morphogenetic protein 4 expression in human cancer cells. Cancer Res. 2002;62:2744-2748.
-
(2002)
Cancer Res.
, vol.62
, pp. 2744-2748
-
-
Kim, J.S.1
Crooks, H.2
Dracheva, T.3
-
35
-
-
13244284605
-
Ren B. beta-Catenin activates the growth factor endothelin-1 in colon cancer cells
-
Kim TH, Xiong H, Zhang Z. Ren B. beta-Catenin activates the growth factor endothelin-1 in colon cancer cells. Oncogene. 2005;24:597-604.
-
(2005)
Oncogene.
, vol.24
, pp. 597-604
-
-
Kim, T.H.1
Xiong, H.2
Zhang, Z.3
-
36
-
-
41549119005
-
Transcriptional program induced by Wnt protein in human fibroblasts suggests mechanisms for cell cooperativity in defining tissue microenvironments
-
Klapholz-Brown Z, Walmsley GG, Nusse YM, Nusse R, Brown PO. Transcriptional program induced by Wnt protein in human fibroblasts suggests mechanisms for cell cooperativity in defining tissue microenvironments. PLoS One. 2007;2:e945.
-
(2007)
PLoS One.
, vol.2
-
-
Klapholz-Brown, Z.1
Walmsley, G.G.2
Nusse, Y.M.3
Nusse, R.4
Brown, P.O.5
-
37
-
-
66249114647
-
Bone morphogenetic protein 4 inhibits TGF-beta2 stimulation of extracellular matrix proteins in optic nerve head cells: Role of gremlin in ECM modulation
-
Zode GS, Clark AF, Wordinger RJ. Bone morphogenetic protein 4 inhibits TGF-beta2 stimulation of extracellular matrix proteins in optic nerve head cells: role of gremlin in ECM modulation. Glia. 2009;57:755-766.
-
(2009)
Glia.
, vol.57
, pp. 755-766
-
-
Zode, G.S.1
Clark, A.F.2
Wordinger, R.J.3
-
38
-
-
0026623462
-
Nitric oxide and endothelin-1 are important regulators of human ophthalmic artery
-
Haefliger IO, Flammer J, Luscher TF. Nitric oxide and endothelin-1 are important regulators of human ophthalmic artery. Invest Ophthalmol Vis Sci. 1992;33:2340-2343.
-
(1992)
Invest Ophthalmol Vis Sci.
, vol.33
, pp. 2340-2343
-
-
Haefliger, I.O.1
Flammer, J.2
Luscher, T.F.3
-
39
-
-
64649096639
-
Myocilin is a modulator of Wnt signaling
-
Kwon HS, Lee HS, Ji Y, Rubin JS, Tomarev SI. Myocilin is a modulator of Wnt signaling. Mol Cell Biol. 2009;29:2139-2154.
-
(2009)
Mol Cell Biol.
, vol.29
, pp. 2139-2154
-
-
Kwon, H.S.1
Lee, H.S.2
Ji, Y.3
Rubin, J.S.4
Tomarev, S.I.5
-
41
-
-
0347087570
-
Beta-catenin signaling in prostate cancer: An early perspective
-
Chesire DR, Isaacs WB. Beta-catenin signaling in prostate cancer: an early perspective. Endocr Relat Cancer. 2003;10: 537-560.
-
(2003)
Endocr Relat Cancer.
, vol.10
, pp. 537-560
-
-
Chesire, D.R.1
Isaacs, W.B.2
-
42
-
-
1542347695
-
Convergence of Wnt, beta-catenin, and cadherin pathways
-
Nelson WJ, Nusse R. Convergence of Wnt, beta-catenin, and cadherin pathways. Science. 2004;303:1483-1487.
-
(2004)
Science.
, vol.303
, pp. 1483-1487
-
-
Nelson, W.J.1
Nusse, R.2
-
43
-
-
84887212494
-
Cadherin-bound beta-catenin feeds into the Wnt pathway upon adherens junctions dissociation: Evidence for an intersection between beta-catenin pools
-
Kam Y, Quaranta V. Cadherin-bound beta-catenin feeds into the Wnt pathway upon adherens junctions dissociation: evidence for an intersection between beta-catenin pools. PLoS One. 2009;4:e4580.
-
(2009)
PLoS One.
, vol.4
-
-
Kam, Y.1
Quaranta, V.2
-
44
-
-
84859502229
-
SFRP1 promoter methylation and expression in human trabecular meshwork cells
-
Mao W, Rubin JS, Anoruo N, Wordinger RJ, Clark AF. SFRP1 promoter methylation and expression in human trabecular meshwork cells. Exp Eye Res. 2012;97:130-136.
-
(2012)
Exp Eye Res.
, vol.97
, pp. 130-136
-
-
Mao, W.1
Rubin, J.S.2
Anoruo, N.3
Wordinger, R.J.4
Clark, A.F.5
|