Lumican, an extracellular matrix proteoglycan, is a novel requisite for hepatic fibrosis

Laboratory Investigation

Volumn 92, Issue 12, 2012, Pages 1712-1725

  Krishnan, Anuradha ^a   Li, Xia ^a   Kao, Winstonwhei Yang ^b   Viker, Kimberly ^a   Butters, Kim ^a   Masuoka, Howard ^a   Knudsen, Bruce ^a   Gores, Gregory ^a   Charlton, Michael ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

Author keywords

arbon tetrachloride; collagen; extracellular matrix; hepatic fibrosis; lumican; proteoglycan; transforming growth factor 1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN FIBRIL; COLLAGEN TYPE 1; COLLAGENASE 3; LUMICAN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; FIBROBLAST; GENE EXPRESSION; LIVER; LIVER FIBROSIS; LIVER INJURY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STRUCTURE ANALYSIS; TURNOVER TIME; WILD TYPE;

ANIMALS; CARBON TETRACHLORIDE; CELL LINE; CELL PROLIFERATION; CHONDROITIN SULFATE PROTEOGLYCANS; COLLAGEN; DIET; FATTY LIVER; HEPATOCYTES; HISTOCYTOCHEMISTRY; HUMANS; KERATAN SULFATE; LIVER; LIVER CIRRHOSIS, EXPERIMENTAL; MICE; MICE, INBRED C57BL; STATISTICS, NONPARAMETRIC; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84870408953     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2012.121     Document Type: Article

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