-
1
-
-
44649120132
-
Chemokine signaling via the CXCR2 receptor reinforces senescence
-
Acosta JC, et al. 2008. Chemokine signaling via the CXCR2 receptor reinforces senescence. Cell 133:1006 -1018.
-
(2008)
Cell
, vol.133
, pp. 1006-1018
-
-
Acosta, J.C.1
-
2
-
-
3843084078
-
The COSMIC (catalogue of somatic mutations in cancer) database and website
-
Bamford S, et al. 2004. The COSMIC (catalogue of somatic mutations in cancer) database and website. Br. J. Cancer. 91:355-358.
-
(2004)
Br. J. Cancer.
, vol.91
, pp. 355-358
-
-
Bamford, S.1
-
3
-
-
33845235459
-
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
-
Bartkova J, et al. 2006. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 444: 633-637.
-
(2006)
Nature
, vol.444
, pp. 633-637
-
-
Bartkova, J.1
-
4
-
-
42549096546
-
Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease
-
Bovolenta P, Esteve P, Ruiz JM, Cisneros E, Lopez-Rios J. 2008. Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease. J. Cell Sci. 121:737-746.
-
(2008)
J. Cell Sci.
, vol.121
, pp. 737-746
-
-
Bovolenta, P.1
Esteve, P.2
Ruiz, J.M.3
Cisneros, E.4
Lopez-Rios, J.5
-
5
-
-
10744229341
-
The Wnt antagonist sFRP1 in colorectal tumorigenesis
-
Caldwell GM, et al. 2004. The Wnt antagonist sFRP1 in colorectal tumorigenesis. Cancer Res. 64:883- 888.
-
(2004)
Cancer Res
, vol.64
, pp. 883-888
-
-
Caldwell, G.M.1
-
6
-
-
34548186667
-
Cellular senescence: when bad things happen to good cells
-
Campisi J, d'Adda di Fagagna F. 2007. Cellular senescence: when bad things happen to good cells. Nat. Rev. Mol. Cell Biol. 8:729 -740.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 729-740
-
-
Campisi, J.1
d'Adda di Fagagna, F.2
-
7
-
-
58249122326
-
Small molecule-mediated disruption of Wntdependent signaling in tissue regeneration and cancer
-
Chen B, et al. 2009. Small molecule-mediated disruption of Wntdependent signaling in tissue regeneration and cancer. Nat. Chem. Biol. 5:100 -107.
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 100-107
-
-
Chen, B.1
-
9
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H. 2006. Wnt/beta-catenin signaling in development and disease. Cell 127:469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
10
-
-
77949881221
-
The senescenceassociated secretory phenotype: the dark side of tumor suppression
-
Coppe JP, Desprez PY, Krtolica A, Campisi J. 2010. The senescenceassociated secretory phenotype: the dark side of tumor suppression. Annu. Rev. Pathol. 5:99 -118.
-
(2010)
Annu. Rev. Pathol.
, vol.5
, pp. 99-118
-
-
Coppe, J.P.1
Desprez, P.Y.2
Krtolica, A.3
Campisi, J.4
-
11
-
-
84891713034
-
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
-
Coppe JP, et al. 2008. Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol. 6:2853-2868.
-
(2008)
PLoS Biol
, vol.6
, pp. 2853-2868
-
-
Coppe, J.P.1
-
12
-
-
33845269825
-
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
-
Di Micco R, et al. 2006. Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature 444:638-642.
-
(2006)
Nature
, vol.444
, pp. 638-642
-
-
Di Micco, R.1
-
13
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri GP, et al. 1995. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl. Acad. Sci. U. S. A. 92:9363- 9367.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
-
14
-
-
0000857494
-
An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database
-
Eng JK, McCormack AL, Yates JR III. 1994. An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. J. Am. Soc. Mass Spectrom. 5:976 -989.
-
(1994)
J. Am. Soc. Mass Spectrom.
, vol.5
, pp. 976-989
-
-
Eng, J.K.1
McCormack, A.L.2
Yates III, J.R.3
-
16
-
-
0032875697
-
Quantitative analysis of complex protein mixtures using isotope-coded affinity tags
-
Gygi SP, et al. 1999. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. Nat. Biotechnol. 17:994 -999.
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 994-999
-
-
Gygi, S.P.1
-
17
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hayflick L, Moorhead PS. 1961. The serial cultivation of human diploid cell strains. Exp. Cell Res. 25:585- 621.
-
(1961)
Exp. Cell Res.
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
18
-
-
70349695861
-
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
-
Huang SM, et al. 2009. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature 461:614-620.
-
(2009)
Nature
, vol.461
, pp. 614-620
-
-
Huang, S.M.1
-
19
-
-
52149123619
-
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
-
Jones S, et al. 2008. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 321:1801-1806.
-
(2008)
Science
, vol.321
, pp. 1801-1806
-
-
Jones, S.1
-
20
-
-
0038783316
-
Secreted antagonists of the Wnt signalling pathway
-
Kawano Y, Kypta R. 2003. Secreted antagonists of the Wnt signalling pathway. J. Cell Sci. 116:2627-2634.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 2627-2634
-
-
Kawano, Y.1
Kypta, R.2
-
21
-
-
0037108887
-
Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search
-
Keller A, Nesvizhskii AI, Kolker E, Aebersold R. 2002. Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. Anal. Chem. 74:5383-5392.
-
(2002)
Anal. Chem.
, vol.74
, pp. 5383-5392
-
-
Keller, A.1
Nesvizhskii, A.I.2
Kolker, E.3
Aebersold, R.4
-
23
-
-
44649101304
-
Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network
-
Kuilman T, et al. 2008. Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network. Cell 133:1019 -1031.
-
(2008)
Cell
, vol.133
, pp. 1019-1031
-
-
Kuilman, T.1
-
24
-
-
58849154235
-
Senescence-messaging secretome: SMS-ing cellular stress
-
Kuilman T, Peeper DS. 2009. Senescence-messaging secretome: SMS-ing cellular stress. Nat. Rev. Cancer 9:81-94.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 81-94
-
-
Kuilman, T.1
Peeper, D.S.2
-
25
-
-
79952236214
-
Quantitative proteomics identifies the Myb-Binding Protein p160 as a novel target of the von Hippel-Lindau tumor suppressor
-
doi: 10.1371/journal.pone.0016975
-
Lai Y, Qiao M, Song M, Weintraub ST, Shiio Y. 2011. Quantitative proteomics identifies the Myb-Binding Protein p160 as a novel target of the von Hippel-Lindau tumor suppressor. PLoS One 6:e16975. doi: 10.1371/journal.pone.0016975.
-
(2011)
PLoS One
, vol.6
-
-
Lai, Y.1
Qiao, M.2
Song, M.3
Weintraub, S.T.4
Shiio, Y.5
-
26
-
-
0344737959
-
Automated statistical analysis of protein abundance ratios from data generated by stable-isotope dilution and tandem mass spectrometry
-
Li XJ, Zhang H, Ranish JA, Aebersold R. 2003. Automated statistical analysis of protein abundance ratios from data generated by stable-isotope dilution and tandem mass spectrometry. Anal. Chem. 75:6648-6657.
-
(2003)
Anal. Chem.
, vol.75
, pp. 6648-6657
-
-
Li, X.J.1
Zhang, H.2
Ranish, J.A.3
Aebersold, R.4
-
27
-
-
0031459893
-
SARPs: a family of secreted apoptosis-related proteins
-
Melkonyan HS, et al. 1997. SARPs: a family of secreted apoptosis-related proteins. Proc. Natl. Acad. Sci. U. S. A. 94:13636 -13641.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 13636-13641
-
-
Melkonyan, H.S.1
-
28
-
-
0037667702
-
Rb- mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
-
Narita M, et al. 2003. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 113:703-716.
-
(2003)
Cell
, vol.113
, pp. 703-716
-
-
Narita, M.1
-
29
-
-
79956325949
-
Spatial coupling of mTOR and autophagy augments secretory phenotypes
-
Narita M, et al. 2011. Spatial coupling of mTOR and autophagy augments secretory phenotypes. Science 332:966 -970.
-
(2011)
Science
, vol.332
, pp. 966-970
-
-
Narita, M.1
-
30
-
-
0042338362
-
A statistical model for identifying proteins by tandem mass spectrometry
-
Nesvizhskii AI, Keller A, Kolker E, Aebersold R. 2003. A statistical model for identifying proteins by tandem mass spectrometry. Anal. Chem. 75: 4646-4658.
-
(2003)
Anal. Chem.
, vol.75
, pp. 4646-4658
-
-
Nesvizhskii, A.I.1
Keller, A.2
Kolker, E.3
Aebersold, R.4
-
31
-
-
33845359084
-
Function and biological roles of the Dickkopf family of Wnt modulators
-
Niehrs C. 2006. Function and biological roles of the Dickkopf family of Wnt modulators. Oncogene 25:7469 -7481.
-
(2006)
Oncogene
, vol.25
, pp. 7469-7481
-
-
Niehrs, C.1
-
32
-
-
70350125106
-
Cell surface-bound IL-1α is an upstream regulator of the senescenceassociated IL-6/IL-8 cytokine network
-
Orjalo AV, Bhaumik D, Gengler BK, Scott GK, Campisi J. 2009. Cell surface-bound IL-1α is an upstream regulator of the senescenceassociated IL-6/IL-8 cytokine network. Proc. Natl. Acad. Sci. U. S. A. 106: 17031-17036.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 17031-17036
-
-
Orjalo, A.V.1
Bhaumik, D.2
Gengler, B.K.3
Scott, G.K.4
Campisi, J.5
-
33
-
-
0042195820
-
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts
-
Parrinello S, et al. 2003. Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts. Nat. Cell Biol. 5:741-747.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 741-747
-
-
Parrinello, S.1
-
34
-
-
68249096784
-
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion
-
Rodier F, et al. 2009. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nat. Cell Biol. 11:973- 979.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 973-979
-
-
Rodier, F.1
-
35
-
-
34250657012
-
Quantitative proteome analysis using isotope-coded affinity tags and mass spectrometry
-
Shiio Y, Aebersold R. 2006. Quantitative proteome analysis using isotope-coded affinity tags and mass spectrometry. Nat. Protoc. 1:139 -145.
-
(2006)
Nat. Protoc.
, vol.1
-
-
Shiio, Y.1
Aebersold, R.2
-
36
-
-
0036792719
-
Quantitative proteomic analysis of Myc oncoprotein function
-
Shiio Y, et al. 2002. Quantitative proteomic analysis of Myc oncoprotein function. EMBO J. 21:5088 -5096.
-
(2002)
EMBO J
, vol.21
, pp. 5088-5096
-
-
Shiio, Y.1
-
37
-
-
33646362301
-
Quantitative proteomic analysis of Myc-induced apoptosis: a direct role for Myc induction of the mitochondrial chloride ion channel, mtCLIC/CLIC4
-
Shiio Y, et al. 2006. Quantitative proteomic analysis of Myc-induced apoptosis: a direct role for Myc induction of the mitochondrial chloride ion channel, mtCLIC/CLIC4. J. Biol. Chem. 281:2750 -2756.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 2750-2756
-
-
Shiio, Y.1
-
38
-
-
0036613250
-
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
-
Suzuki H, et al. 2002. A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer. Nat. Genet. 31:141-149.
-
(2002)
Nat. Genet.
, vol.31
, pp. 141-149
-
-
Suzuki, H.1
-
39
-
-
78650484935
-
Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes
-
Taelman VF, et al. 2010. Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes. Cell 143:1136 -1148.
-
(2010)
Cell
, vol.143
, pp. 1136-1148
-
-
Taelman, V.F.1
-
40
-
-
77958171338
-
Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α
-
Thorne CA, et al. 2010. Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α. Nat. Chem. Biol. 6:829-836.
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 829-836
-
-
Thorne, C.A.1
-
41
-
-
49649103241
-
Expression of secreted frizzled related protein 1, a Wnt antagonist, in brain, kidney, and skeleton is dispensable for normal embryonic development
-
Trevant B, et al. 2008. Expression of secreted frizzled related protein 1, a Wnt antagonist, in brain, kidney, and skeleton is dispensable for normal embryonic development. J. Cell. Physiol. 217:113-126.
-
(2008)
J. Cell. Physiol.
, vol.217
, pp. 113-126
-
-
Trevant, B.1
-
42
-
-
0030902371
-
Protein kinase C activation upregulates intercellular adhesion of alpha-catenin-negative human colon cancer cell variants via induction of desmosomes
-
van Hengel J, et al. 1997. Protein kinase C activation upregulates intercellular adhesion of alpha-catenin-negative human colon cancer cell variants via induction of desmosomes. J. Cell Biol. 137:1103-1116.
-
(1997)
J. Cell Biol.
, vol.137
, pp. 1103-1116
-
-
van Hengel, J.1
-
43
-
-
0344373791
-
Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements
-
Veeman MT, Slusarski DC, Kaykas A, Louie SH, Moon RT. 2003. Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements. Curr. Biol. 13:680-685.
-
(2003)
Curr. Biol.
, vol.13
, pp. 680-685
-
-
Veeman, M.T.1
Slusarski, D.C.2
Kaykas, A.3
Louie, S.H.4
Moon, R.T.5
-
44
-
-
34447343780
-
Downregulation of Wnt signaling is a trigger for formation of facultative heterochromatin and onset of cell senescence in primary human cells
-
Ye X, et al. 2007. Downregulation of Wnt signaling is a trigger for formation of facultative heterochromatin and onset of cell senescence in primary human cells. Mol. Cell 27:183-196.
-
(2007)
Mol. Cell
, vol.27
, pp. 183-196
-
-
Ye, X.1
-
45
-
-
77954851049
-
Wnt signaling regulates mitochondrial physiology and insulin sensitivity
-
Yoon JC, et al. 2010. Wnt signaling regulates mitochondrial physiology and insulin sensitivity. Genes Dev. 24:1507-1518.
-
(2010)
Genes Dev
, vol.24
, pp. 1507-1518
-
-
Yoon, J.C.1
|