Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via nuclear exit of a mechanorepressor

Nature Materials

Volumn 14, Issue 9, 2015, Pages 951-960

  Dingal, P C Dave P ^a   Bradshaw, Andrew M ^a   Cho, Sangkyun ^a   Raab, Matthew ^a   Buxboim, Amnon ^a   Swift, Joe ^a   Discher, Dennis E ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Stanford University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; FLOWCHARTING; FRACTALS; PROTEINS; STEM CELLS;

ADHESIVE LIGANDS; CELL SPREADING; LONG LASTING; MECHANICAL MEMORY; MESENCHYMAL STEM CELL; MINIMAL MATRIX; OVER-EXPRESSION; SMOOTH MUSCLE ACTINS;

CELL CULTURE;

ACRYLIC ACID RESIN; ACTIN; ALPHA-SMOOTH MUSCLE ACTIN, MOUSE; COLLAGEN TYPE 1; HOMEODOMAIN PROTEIN; NKX2-5 PROTEIN, MOUSE; POLYACRYLAMIDE; TRANSCRIPTION FACTOR;

ACTIVE TRANSPORT; ANIMAL; BIOLOGICAL MODEL; CELL NUCLEUS; CHEMISTRY; EXTRACELLULAR MATRIX; MESENCHYMAL STROMA CELL; METABOLISM; MOUSE; PATHOLOGY; SCAR; STEM CELL NICHE;

ACRYLIC RESINS; ACTINS; ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL NUCLEUS; CICATRIX; COLLAGEN TYPE I; EXTRACELLULAR MATRIX; HOMEODOMAIN PROTEINS; MESENCHYMAL STROMAL CELLS; MICE; MODELS, BIOLOGICAL; STEM CELL NICHE; TRANSCRIPTION FACTORS;

EID: 84939791703     PISSN: 14761122     EISSN: 14764660     Source Type: Journal    
DOI: 10.1038/nmat4350     Document Type: Article

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