Actin dynamics control SRF activity by regulation of its coactivator MAL

Cell

Volumn 113, Issue 3, 2003, Pages 329-342

  Miralles, Francesc ^a   Posern, Guido ^a   Zaromytidou, Alexia Ileana ^a   Treisman, Richard ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; PROTEIN; PROTEIN MAL; RHO FACTOR; SERUM RESPONSE FACTOR; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CYTOPLASM; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN MOTIF; SIGNAL TRANSDUCTION;

EID: 0038737042     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(03)00278-2     Document Type: Article

References (31)

1. Alberts A.S., Geneste O., Treisman R. Activation of SRF-regulated chromosomal templates by Rho-family GTPases requires a signal that also induces H4 hyperacetylation. Cell. 92:1998;475-487.
2. Arsenian S., Weinhold B., Oelgeschlager M., Ruther U., Nordheim A. Serum response factor is essential for mesoderm formation during mouse embryogenesis. EMBO J. 17:1998;6289-6299.
3. Bhowmick N.A., Ghiassi M., Bakin A., Aakre M., Lundquist C.A., Engel M.E., Arteaga C.L., Moses H.L. Transforming growth factor-β1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism. Mol. Biol. Cell. 12:2001;27-36.
4. Copeland J., Treisman R. Activation of SRF by the diaphanous related formin mDia1 is mediated by its effects on actin polymerisation. Mol. Biol. Cell. 13:2002;4088-4099.
5. Geneste O., Copeland J.W., Treisman R. LIM kinase and diaphanous cooperate to regulate serum response factor and actin dynamics. J. Cell Biol. 157:2002;831-838.
6. Gineitis D., Treisman R. Differential usage of signal transduction pathways defines two types of serum response factor target gene. J. Biol. Chem. 276:2001;24531-24539.
7. Grosse R., Copeland J.W., Newsome T., Way M., Treisman K. A role for VASP in RhoA-diaphanous signaling to F-actin assembly and SRF activation. EMBO J. 22:2003;. in press.
8. Hassler M., Richmond T.J. The B-box dominates SAP-1-SRF interactions in the structure of the ternary complex. EMBO J. 20:2001;3018-3028.
9. Hill C.S., Marais R., John S., Wynne J., Dalton S., Treisman R. Functional analysis of a growth factor-responsive transcription factor complex. Cell. 73:1993;395-406.
10. Hill C.S., Wynne J., Treisman R. Serum-regulated transcription by serum response factor (SRF). a novel role for the DNA binding domain EMBO J. 13:1994;5421-5432.
11. Hill C.S., Wynne J., Treisman R. The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. Cell. 81:1995;1159-1170.
12. Ling Y., Lakey J.H., Roberts C.E., Sharrocks A.D. Molecular characterization of the B-box protein-protein interaction motif of the ETS-domain transcription factor Elk-1. EMBO J. 16:1997;2431-2440.
13. Ma Z., Morris S.W., Valentine V., Li M., Herbrick J.A., Cui X., Bouman D., Li Y., Mehta P.K., Nizetic D.et al. Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia. Nat. Genet. 28:2001;220-221.
14. Mack C.P., Somlyo A.V., Hautmann M., Somlyo A.P., Owens G.K. Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization. J. Biol. Chem. 276:2001;341-347.
15. McCabe J.B., Berthiaume L.G. Functional roles for fatty acylated amino-terminal domains in subcellular localization. Mol. Biol. Cell. 10:1999;3771-3786.
16. Mercher T., Coniat M.B., Monni R., Mauchauffe M., Khac F.N., Gressin L., Mugneret F., Leblanc T., Dastugue N., Berger R., Bernard O.A. Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia. Proc. Natl. Acad. Sci. USA. 98:2001;5776-5779.
17. Murai K., Treisman R. Interaction of serum response factor (SRF) with the Elk-1 B-Box inhibits RhoA-actin signaling to SRF and potentiates transcriptional activation by Elk-1. Mol. Cell. Biol. 22:2002;7083-7092.
18. Oft M., Akhurst R.J., Balmain A. Metastasis is driven by sequential elevation of H-ras and Smad2 levels. Nat. Cell Biol. 4:2002;487-494.
19. Posern G., Rapp U.R., Feller S.M. The Crk signaling pathway contributes to the bombesin-induced activation of the small GTPase Rap1 in Swiss 3T3 cells. Oncogene. 19:2000;6361-6368.
20. Posern G., Sotiropoulos A., Treisman R. Mutant actins reveal a role for unpolymerised actin in control of transcription by serum response factor. Mol. Biol. Cell. 13:2002;4167-4178.
21. Psichari E., Balmain A., Plows D., Zoumpourlis V., Pintzas A. High activity of serum response factor in the mesenchymal transition of epithelial tumor cells is regulated by RhoA signaling. J. Biol. Chem. 277:2002;29490-29495.
22. Sasazuki T., Sawada T., Sakon S., Kitamura T., Kishi T., Okazaki T., Katano M., Tanaka M., Watanabe M., Yagita H.et al. Identification of a novel transcriptional activator, BSAC, by a functional cloning to inhibit tumor necrosis factor-induced cell death. J. Biol. Chem. 277:2002;28853-28860.
23. Schratt G., Weinhold B., Lundberg A.S., Schuck S., Berger J., Schwarz H., Weinberg R.A., Ruther U., Nordheim A. Serum response factor is required for immediate-early gene activation yet is dispensable for proliferation of embryonic stem cells. Mol. Cell. Biol. 21:2001;2933-2943.
24. Schratt G., Philippar U., Berger J., Schwarz H., Heidenreich O., Nordheim A. Serum response factor is crucial for actin cytoskeletal organization and focal adhesion assembly in embryonic stem cells. J. Cell Biol. 156:2002;737-750.
25. Skarnes W.C., Auerbach B.A., Joyner A.L. A gene trap approach in mouse embryonic stem cells. the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice Genes Dev. 6:1992;903-918.
26. Sotiropoulos A., Gineitis D., Copeland J., Treisman R. Signal-regulated activation of serum response factor is mediated by changes in actin dynamics. Cell. 98:1999;159-169.
27. Tominaga T., Sahai E., Chardin P., McCormick F., Courtneidge S.A., Alberts A.S. Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling. Mol. Cell. 5:2000;13-25.
28. Treisman R. Ternary complex factors. growth factor regulated transcriptional activators Curr. Opin. Genet. Dev. 4:1994;96-101.
29. Wang D., Chang P.S., Wang Z., Sutherland L., Richardson J.A., Small E., Krieg P.A., Olson E.N. Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor. Cell. 105:2001;851-862.
30. Wang D.Z., Li S., Hockemeyer D., Sutherland L., Wang Z., Schratt G., Richardson J.A., Nordheim A., Olson E.N. Potentiation of serum response factor activity by a family of myocardin-related transcription factors. Proc. Natl. Acad. Sci. USA. 99:2002;14855-14860.
31. Weinhold B., Schratt G., Arsenian S., Berger J., Kamino K., Schwarz H., Ruther U., Nordheim A. Srf(-/-) ES cells display non-cell-autonomous impairment in mesodermal differentiation. EMBO J. 19:2000;5835-5844.