Cell shape, spreading symmetry, and the polarization of stress-fibers in cells

Journal of Physics Condensed Matter

Volumn 22, Issue 19, 2010, Pages

  Zemel, A ^a   Rehfeldt, F ^b,c   Brown, A E X ^c,d   Discher, D E ^c   Safran, S A ^e  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^e WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SHAPES; CELL SIZE; CELL SPREADING; CELL TYPES; CELLULAR FORCE; CYTOSKELETONS; ELASTIC MODELS; ELONGATED STRUCTURES; FIBER ALIGNMENT; IN-CELL; IN-VITRO; INTERNAL STRUCTURE; ISOTROPIC SUBSTRATES; LOCAL DISTRIBUTIONS; MATRIX RIGIDITY; MECHANICAL ENVIRONMENT; NATIVE ENVIRONMENT;

ADHESION; ALIGNMENT; CELL ADHESION; POLARIZATION; PRESSURE EFFECTS; RIGIDITY;

STEM CELLS;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; CELL ADHESION; CELL MOTION; CELL SIZE; COMPUTER SIMULATION; FOCAL ADHESION; HUMAN; MECHANICAL STRESS; MECHANOTRANSDUCTION; PHYSIOLOGY; STEM CELL; YOUNG MODULUS;

ANIMALS; CELL ADHESION; CELL MOVEMENT; CELL SIZE; COMPUTER SIMULATION; ELASTIC MODULUS; FOCAL ADHESIONS; HUMANS; MECHANOTRANSDUCTION, CELLULAR; MODELS, BIOLOGICAL; STEM CELLS; STRESS, MECHANICAL;

EID: 77951590156     PISSN: 09538984     EISSN: 1361648X     Source Type: Journal    
DOI: 10.1088/0953-8984/22/19/194110     Document Type: Article

References (50)

1. Chen C S, Mrksich M, Huang S, Whitesides G M and Ingber D E 1997 Geometric control of cell life and death Science 276 1425-8
2. McBeath R, Pirone D M, Nelson C M, Bhadriraju K and Chen C S 2004 Cell shape, cytoskeleton tension, and RohA regulate stem cell lineage commitment Dev. Cell 6 483-95
3. Engler A J et al. 2004 Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments J. Cell Biol. 166 877-87
4. Yeung T et al. 2005 Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion Cell Motil. Cytoskeleton 60 24-34
5. Discher D E, Janmey P and Wang Y 2005 Tissue cells feel and respond to the stiffness of their substrate Science 310 1139-43
6. Engler A J, Sen S, Sweeney H L and Discher D E 2006 Matrix elasticity directs stem cell lineage specification Cell 126 677-89
7. Georges P C, Miller W J, Meaney D F, Sawyer E S and Janmey P A 2006 Matrices with compliance comparable to that of brain tissue select neuronal over glial growth in mixed cortical cultures Biophys. J. 90 3012-8
8. Ruiz S A and Chen C S 2008 Emergence of patterned stem cell differentiation within multicellular structures Stem Cells 26 2921-7
9. Discher D E, Mooney D J and Zandstra P W 2009 Growth factors, matrices, and forces combine and control stem cells Science 324 1673-7
10. Grinnell F 2000 Fibroblast-collagen-matrix contraction: growth-factor signalling and mechanical loading Trends Cell Biol. 10 362-5
11. Wang N et al. 2002 Cell prestress. I. Stiffness and prestress are closely associated in adherent contractile cells Am. J. Physiol. Cell Physiol. 282 C606-16
12. Kumar S et al. 2006 Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization, and extracellular matrix mechanics Biophys. J. 90 3762-73
13. Griffin M A et al. 2004 Patterning, prestress, and peeling dynamics of myocytes Biophys. J. 1209-22
14. Dubin-Thaler B J et al. 2008 Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading PLOS One 3 e3735
15. Gov N S and Gopinathany A 2006 Dynamics of membranes driven by actin polymerization Biophys. J. 90 454-69
16. Bershadsky A, Kozlov M and Geiger B 2006 Adhesion-mediated mechanosensitivity: a time to experiment, and a time to theorize Curr. Opin. Cell Biol. 18 472-81
17. Wang N, Ostuni E, Whitesides G M and Ingber D E 2002 Micropatterning tractional forces in living cells Cell Motil. Cytoskeleton 52 97-106
18. Théry M, Pépin A, Dressaire E, Chen Y and Bornens M 2006 Cell distribution of stress fibres in response to the geometry of the adhesive environment Cell Motil. Cytoskeleton 63 341-55
19. Deshpande V S, McMeeking R M and Evans A G 2006 A bio-chemo-mechanical model for cell contractility Proc. Natl Acad. Sci. 103 14015-20
20. Zemel A, Rehfeldt F, Brown A E X, Discher D E and Safran S A 2010 Optimal matrix rigidity for stress fiber polarization in stem cells Nat. Phys. doi:10.1038/NPHYS1613
21. Kemkemer R, Neidlinger-Wilke C, Claes L and Gruler H 1999 Cell orientation induced by extracellular signals Cell Biochem. Biophys. 30 167-95
22. Walboomers X F, Monaghan W, Curtis A S G and Jansen J A 1999 Attachment of fibroblasts on smooth and microgrooved polystyrene J. Biomed. Mater. Res. 46 212-20
23. K Kurpinski C H, Chu J and Li S 2006 Anisotropic mechanosensing by mesenchymal stem cells Proc. Natl Acad. Sci. 103 16095-100
24. Liu W F and Chen C S 2007 Cellular and multicellular form and function Adv. Drug Deliv. Rev. 59 1319-28
25. Chicurel M E, Chen C S and Ingber D E 1998 Cellular control lies in the balance of forces Curr. Opin. Cell Biol. 10 232-9
26. Mura T 1991 Micromechanics of Defects in Solids (Dordrecht: Kluwer Academic)
27. Eshelby J D 1957 The determination of elastic field of an ellipsoidal inclusion, and related problems. Proc. R. Soc. A 241 376-96
28. Benveniste Y 1987 A new approach to the application of Mori-Tanaka's theory in composite materials Mech. Mater. 6 147-57
29. Zemel A and Safran S A 2007 Active self-polarization of contractile cells in asymmetrically shaped domains Phys. Rev. E 76 021905
30. Tucker C L and Liang E 1999 Stiffness predictions for unidirectional short-fiber composites: review and evaluation Comput. Sci. Technol. 59 655-71
31. Siems R 1968 Mechanical interactions of point defects Phys. Status Solidi 30 645-58
32. Schwarz U S and Safran S A 2002 Elastic interactions of cells Phys. Rev. Lett. 88 048102
33. Carlsson A E 2006 Contractile stress generation by actomyosin gels Phys. Rev. E 74 051912
34. Chrzanowska-Wodnicka M and Burridge K 1996 Rho-stimulated contractility drives the formation of stress fibers and focal adhesions J. Cell Biol. 133 1403-15
35. Burridge K and Chrzanowska-Wodnicka M 1996 Focal adhesions, contractility, and signaling Ann. Rev. Cell Dev. Biol. 12 463-519
36. Kittel C 1986 Introduction to Solid State Physics 6th edn (New York: Wiley)
37. Landau L D and Lifshitz E M 1986 Theory of Elasticity (Course of Theoretical Physics vol 7) 3rd edn (Amsterdam: Elsevier)
38. Jaswon M A and Bhargava R D 1961 Two-dimensional elastic inclusion problems Proc. Phil. Soc. 57 669-80
39. Eshelby J D 1959 The elastic field outside an ellipsoidal inclusion. Proc. R. Soc. A 252 561-9
40. Zemel A, Bischofs I B and Safran S A 2006 Active elasticity of gels with contractile cells Phys. Rev. Lett. 97 128103
41. Théry M et al. 2006 Anisotropy of cell adhesive microenvironment governs cell internal organization and orientation of polarity Proc. Natl Acad. Sci. 103 19771-6
42. Curtis A, Aitchison G and Tsapikouni T 2006 Orthogonal (transverse) arrangements of actin in endothelia and fibroblasts J. R. Soc. Interface 3 753-6
43. Ghibaudo M et al. 2008 Traction forces and rigidity sensing regulate cell functions Soft Matter. 4 1836-43
44. Rasband W S 1997-2007 ImageJ, US National Institute of Health, Bethesda, Maryland, USA http://rsb.info.nih.gov/ij/
45. Pelham R J and Wang Y L 1997 Cell locomotion and focal adhesions are regulated by substrate flexibility Proc. Natl Acad. Sci. USA 94 13661-5
46. Engler A J, Rehfeldt F, Sen S and Discher D E 2007 Microtissue Elasticity: Measurements by Atomic Force Microscopy and its Influence on Cell Differentiation vol 83 (New York: Academic) pp521-45
47. Otsu N 1979 Threshold selection method from gray-level histogrames IEEE Trans. Syst. Man Cybern. 9 62-6
48. Storm C, Pastore J J, MacKintosh F C, Lubensky T C and Janmey P A 2005 Nonlinear elasticity in biological gels Nature 435 191-4
49. Gardel M L et al. 2006 Prestressed f-actin networks cross-linked by hinged filamins replicate mechanical properties of cells Proc. Natl Acad. Sci. 103 1762-7
50. Koenderink G H et al. 2009 An active biopolymer network controlled by molecular motors Proc. Natl Acad. Sci. 106 15192-7