A quantitative approach to scar analysis

American Journal of Pathology

Volumn 178, Issue 2, 2011, Pages 621-628

  Khorasani, Hooman ^a   Zheng, Zhong ^b   Nguyen, Calvin ^c   Zara, Janette ^d   Zhang, Xinli ^b   Wang, Joyce ^e   Ting, Kang ^b,c,d   Soo, Chia ^b,c  

^a MOUNT SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d University of California   (United States)

^e UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; FIBROMODULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL ASSESSMENT TOOL; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ELECTRON MICROSCOPY; FOURIER TRANSFORMATION; FRACTAL DIMENSION; HISTOPATHOLOGY; INTERMETHOD COMPARISON; LACUNARITY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCAR; SCAR FORMATION; SKINFOLD THICKNESS; WOUND;

EID: 79951816363     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2010.10.019     Document Type: Article

References (30)

1. Gibson T: The physical properties of skin. Edited by J Converse. Philadelphia, WB Saunders, 1990, pp 207-220
2. Peacock E: Contraction. Edited by E Peacock. Philadelphia, WB Saunders, 1984, pp 38-90
3. van Zuijlen PP, de Vries HJ, Lamme EN, Coppens JE, van Marle J, Kreis RW, Middelkoop E: Morphometry of dermal collagen orientation by Fourier analysis is superior to multi-observer assessment. J Pathol 2002, 198:284-291 (Pubitemid 35277378)
4. Verhaegen PD, Res EM, van Engelen A, Middelkoop E, van Zuijlen PP. A reliable, non-invasive measurement tool for anisotropy in normal skin and scar tissue. Skin Res Technol 2010, 16:325-331
5. van Zuijlen PP, Ruurda JJ, van Veen HA, van Marle J, van Trier AJ, Groenevelt F, Kreis RW, Middelkoop E: Collagen morphology in human skin and scar tissue: no adaptations in response to mechanical loading at joints. Burns 2003, 29:423-431 (Pubitemid 36918273)
6. Wolman M, Gillman T: A polarized light study of collagen in dermal wound healing. Br J Exp Pathol 1972, 53:85-89
7. Wolman M, Kasten FH: Polarized light microscopy in the study of the molecular structure of collagen and reticulin. Histochemistry 1986, 85:41-49
8. Brodsky B, Ramshaw JA: Collagen organization in an oriented fibrous capsule. Int J Biol Macromol 1994, 16:27-30 (Pubitemid 24051854)
9. Purslow PP, Wess TJ, Hukins DW: Collagen orientation and molecular spacing during creep and stress-relaxation in soft connective tissues. J Exp Biol 1998, 201:135-142 (Pubitemid 28065671)
10. Ferdman AG, Yannas IV: Scattering of light from histologic sections: a new method for the analysis of connective tissue. J Invest Dermatol 1993, 100:710-716 (Pubitemid 23128371)
11. Bowes LE, Jimenez MC, Hiester ED, Sacks MS, Brahmatewari J, Mertz P, Eaglstein WH: Collagen fiber orientation as quantified by small angle light scattering in wounds treated with transforming growth factor-beta2 and its neutralizing antibody. Wound Repair Regeneration 1999, 7:179-186 (Pubitemid 29331922)
12. de Vries HJ, Enomoto DN, van Marle J, van Zuijlen PP, Mekkes JR, Bos JD: Dermal organization in scleroderma: the fast Fourier transform and the laser scatter method objectify fibrosis in nonlesional as well as lesional skin. Lab Invest 2000, 80:1281-1289 (Pubitemid 30637068)
13. Smith TG Jr., Lange GD, Marks WB: Fractal methods and results in cellular morphology-dimensions, lacunarity and multifractals. J Neurosci Methods 1996, 69:123-136 (Pubitemid 26377770)
14. Mandelbrot BB: The fractal geometry of nature. New York, W.H. Freeman & Co., 1983, pp 14-19, 310-318
15. Eblen-Zajjur A, Salas R, Vanegas H: Fractal analysis of spinal dorsal horn neuron discharges by means of sequential fractal dimension D. Comput Biol Med 1996, 26:87-95 (Pubitemid 26046744)
16. Tinajero JP, Robledo RF, Lantz RC, Sobonya RE, Quan SF, Lemen RJ, Tollinger BJ, Witten ML: Fractal analysis of lung alveoli during the acute phase vs. repair phase of an adenoviral infection in canines. Res Commun Mol Pathol Pharmacol 1997, 95:275-285 (Pubitemid 27208734)
17. Guidolin D, Vacca A, Nussdorfer GG, Ribatti D: A new image analysis method based on topological and fractal parameters to evaluate the angiostatic activity of docetaxel by using the Matrigel assay in vitro. Microvasc Res 2004, 67:117-124 (Pubitemid 38326997)
18. Oldberg A, Antonsson P, Lindblom K, Heinegard D: A collagen-binding 59-kd protein (fibromodulin) is structurally related to the small interstitial proteoglycans PG-S1 and PG-S2 (decorin). EMBO J 1989, 8:2601-2604
19. Vogel KG, Trotter JA: The effect of proteoglycans on the morphology of collagen fibrils formed in vitro. Coll Relat Res 1987, 7:105-114
20. Garg AK, Berg RA, Silver FH, Garg HG: Effect of proteoglycans on type I collagen fibre formation. Biomaterials 1989, 10:413-419 (Pubitemid 19214776)
21. Svensson L, Narlid I, Oldberg A: Fibromodulin and lumican bind to the same region on collagen type I fibrils. FEBS Lett 2000, 470:178-182 (Pubitemid 30151092)
22. Hedlund H, Mengarelli-Widholm S, Heinegard D, Reinholt FP, Svensson O: Fibromodulin distribution and association with collagen. Matrix Biol 1994, 14:227-232 (Pubitemid 24136382)
23. Font B, Eichenberger D, Goldschmidt D, Boutillon MM, Hulmes DJ: Structural requirements for fibromodulin binding to collagen and the control of type I collagen fibrillogenesis- critical roles for disulphide bonding and the C-terminal region. Eur J Biochem 1998, 254:580-587 (Pubitemid 28308109)
24. Soo C, Beanes SR, Hu FY, Zhang X, Dang C, Chang G, Wang Y, Nishimura I, Freymiller E, Longaker MT, Lorenz HP, Ting K: Ontogenetic transition in fetal wound transforming growth factor-beta regulation correlates with collagen organization. Am J Pathol 2003, 163:2459-2476 (Pubitemid 37466487)
25. Scott JE, Orford CR: Dermatan sulphate-rich proteoglycan associates with rat tail-tendon collagen at the d band in the gap region. Biochem J 1981, 197:213-216 (Pubitemid 11060360)
26. Dolber PC, Spach MS: Conventional and confocal fluorescence microscopy of collagen fibers in the heart. J Histochem Cytochem 1993, 41:465-469 (Pubitemid 23061934)
27. Danielson KG, Baribault H, Holmes DF, Graham H, Kadler KE, Iozzo RV: Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility. J Cell Biol 1997, 136:729-743 (Pubitemid 27083772)
28. Chakravarti S, Magnuson T, Lass JH, Jepsen KJ, LaMantia C, Carroll H: Lumican regulates collagen fibril assembly: skin fragility and corneal opacity in the absence of lumican. J Cell Biol 1998, 141:1277-1286 (Pubitemid 28265620)
29. Cheon SS, Wei Q, Gurung A, Youn A, Bright T, Poon R, Whetstone H, Guha A, Alman BA: Beta-catenin regulates wound size and mediates the effect of TGF-beta in cutaneous healing. FASEB J 2006, 20:692-701 (Pubitemid 44933313)
30. Stoff A, Rivera AA, Mathis JM, Moore ST, Banerjee NS, Everts M, Espinosa-de-Los-Monteros A, Novak Z, Vasconez LO, Broker TR, Richter DF, Feldman D, Siegal GP, Stoff-Khalili MA, Curiel DT: Effect of adenoviral mediated overexpression of fibromodulin on human dermal fibroblasts and scar formation in full-thickness incisional wounds, J Mol Med 2007, 85:481-496 (Pubitemid 46701657)