-
1
-
-
1042267249
-
Osteoarthritis: Is it a disease of cartilage or of bone?
-
Felson DT, Neogi T: Osteoarthritis: is it a disease of cartilage or of bone? Arthritis Rheum 2004;50:341-344.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 341-344
-
-
Felson, D.T.1
Neogi, T.2
-
2
-
-
1042278738
-
Is osteoarthritis a systemic disorder of bone?
-
Rogers J, Shepstone L, Dieppe P: Is osteoarthritis a systemic disorder of bone? Arthritis Rheum 2004;50:452-457.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 452-457
-
-
Rogers, J.1
Shepstone, L.2
Dieppe, P.3
-
3
-
-
43349090801
-
Factors that may mediate the relationship between physical activity and the risk for developing knee osteoarthritis
-
Urquhart DM, Soufan C, Teichtahl AJ, Wluka AE, Hanna F, Cicuttini FM: Factors that may mediate the relationship between physical activity and the risk for developing knee osteoarthritis. Arthritis Res Ther 2008;10:203.
-
(2008)
Arthritis Res Ther
, vol.10
, pp. 203
-
-
Urquhart, D.M.1
Soufan, C.2
Teichtahl, A.J.3
Wluka, A.E.4
Hanna, F.5
Cicuttini, F.M.6
-
4
-
-
84893855866
-
Honokiol, a low molecular weight natural product, prevents inflammatory response and cartilage matrix degradation in human osteoarthritis chondrocytes
-
Chen YJ, Tsai KS, Chan DC, Lan KC, Chen CF, Yang RS, Liu SH: Honokiol, a low molecular weight natural product, prevents inflammatory response and cartilage matrix degradation in human osteoarthritis chondrocytes. J Orthop Res 2014;32:573-580.
-
(2014)
J Orthop Res
, vol.32
, pp. 573-580
-
-
Chen, Y.J.1
Tsai, K.S.2
Chan, D.C.3
Lan, K.C.4
Chen, C.F.5
Yang, R.S.6
Liu, S.H.7
-
5
-
-
0033638543
-
Apoptosis in normal and osteoarthritic human articular cartilage
-
Heraud F, Heraud A, Harmand MF: Apoptosis in normal and osteoarthritic human articular cartilage. Ann Rheum Dis 2000;59:959-965.
-
(2000)
Ann Rheum Dis
, vol.59
, pp. 959-965
-
-
Heraud, F.1
Heraud, A.2
Harmand, M.F.3
-
6
-
-
84857050272
-
Hypoxia-inducible factor-2alpha regulates fas-mediated chondrocyte apoptosis during osteoarthritic cartilage destruction
-
Ryu JH, Shin Y, Huh YH, Yang S, Chun CH, Chun JS: Hypoxia-inducible factor-2alpha regulates fas-mediated chondrocyte apoptosis during osteoarthritic cartilage destruction. Cell Death Differ 2012;19:440-450.
-
(2012)
Cell Death Differ
, vol.19
, pp. 440-450
-
-
Ryu, J.H.1
Shin, Y.2
Huh, Y.H.3
Yang, S.4
Chun, C.H.5
Chun, J.S.6
-
7
-
-
84901974939
-
Baicalein ameliorates inflammatoryrelated apoptotic and catabolic phenotypes in human chondrocytes
-
Zhang X, Zhu Y, Chen X, Zhang Y, Zhang Y, Jia Y, Wang H, Liu Y, Xiao L: Baicalein ameliorates inflammatoryrelated apoptotic and catabolic phenotypes in human chondrocytes. Int Immunopharmacol 2014;21:301-308.
-
(2014)
Int Immunopharmacol
, vol.21
, pp. 301-308
-
-
Zhang, X.1
Zhu, Y.2
Chen, X.3
Zhang, Y.4
Zhang, Y.5
Jia, Y.6
Wang, H.7
Liu, Y.8
Xiao, L.9
-
8
-
-
79955150127
-
Chondrocyte death by apoptosis is associated with the initiation and severity of articular cartilage degradation
-
Thomas CM, Fuller CJ, Whittles CE, Sharif M: Chondrocyte death by apoptosis is associated with the initiation and severity of articular cartilage degradation. Int J Rheum Dis 2011;14:191-198.
-
(2011)
Int J Rheum Dis
, vol.14
, pp. 191-198
-
-
Thomas, C.M.1
Fuller, C.J.2
Whittles, C.E.3
Sharif, M.4
-
9
-
-
84863310849
-
Requirement of the phosphatidylinositol 3-kinase/akt signaling pathway for the effect of nicotine on interleukin-1beta-induced chondrocyte apoptosis in a rat model of osteoarthritis
-
Zheng X, Xia C, Chen Z, Huang J, Gao F, Li G, Zhang B: Requirement of the phosphatidylinositol 3-kinase/akt signaling pathway for the effect of nicotine on interleukin-1beta-induced chondrocyte apoptosis in a rat model of osteoarthritis. Biochem Biophys Res Commun 2012;423:606-612.
-
(2012)
Biochem Biophys Res Commun
, vol.423
, pp. 606-612
-
-
Zheng, X.1
Xia, C.2
Chen, Z.3
Huang, J.4
Gao, F.5
Li, G.6
Zhang, B.7
-
10
-
-
27544466756
-
Osteoblasts from the sclerotic subchondral bone downregulate aggrecan but upregulate metalloproteinases expression by chondrocytes. This effect is mimicked by interleukin-6, -1beta and oncostatin m pre-treated non-sclerotic osteoblasts
-
Sanchez C, Deberg MA, Piccardi N, Msika P, Reginster JY, Henrotin YE: Osteoblasts from the sclerotic subchondral bone downregulate aggrecan but upregulate metalloproteinases expression by chondrocytes. This effect is mimicked by interleukin-6, -1beta and oncostatin m pre-treated non-sclerotic osteoblasts. Osteoarthritis Cartilage 2005;13:979-987.
-
(2005)
Osteoarthritis Cartilage
, vol.13
, pp. 979-987
-
-
Sanchez, C.1
Deberg, M.A.2
Piccardi, N.3
Msika, P.4
Reginster, J.Y.5
Henrotin, Y.E.6
-
11
-
-
0036948412
-
Antimicrobial and immunoregulatory functions of lactoferrin and its potential therapeutic application
-
Caccavo D, Pellegrino NM, Altamura M, Rigon A, Amati L, Amoroso A, Jirillo E: Antimicrobial and immunoregulatory functions of lactoferrin and its potential therapeutic application. J Endotoxin Res 2002;8:403-417.
-
(2002)
J Endotoxin Res
, vol.8
, pp. 403-417
-
-
Caccavo, D.1
Pellegrino, N.M.2
Altamura, M.3
Rigon, A.4
Amati, L.5
Amoroso, A.6
Jirillo, E.7
-
12
-
-
80051793186
-
Lactoferrin inhibits neutrophil apoptosis via blockade of proximal apoptotic signaling events
-
Francis N, Wong SH, Hampson P, Wang K, Young SP, Deigner HP, Salmon M, Scheel-Toellner D, Lord JM: Lactoferrin inhibits neutrophil apoptosis via blockade of proximal apoptotic signaling events. Biochim Biophys Acta 2011;1813:1822-1826.
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 1822-1826
-
-
Francis, N.1
Wong, S.H.2
Hampson, P.3
Wang, K.4
Young, S.P.5
Deigner, H.P.6
Salmon, M.7
Scheel-Toellner, D.8
Lord, J.M.9
-
13
-
-
84898769214
-
Lactoferrin inhibits apoptosis through insulinlike growth factor i in primary rat osteoblasts
-
Hou JM, Chen EY, Wei SC, Lin F, Lin QM, Lan XH, Xue Y, Wu M: Lactoferrin inhibits apoptosis through insulinlike growth factor i in primary rat osteoblasts. Acta Pharmacol Sin 2014;35:523-530.
-
(2014)
Acta Pharmacol Sin
, vol.35
, pp. 523-530
-
-
Hou, J.M.1
Chen, E.Y.2
Wei, S.C.3
Lin, F.4
Lin, Q.M.5
Lan, X.H.6
Xue, Y.7
Wu, M.8
-
14
-
-
4344694236
-
Lactoferrin is a potent regulator of bone cell activity and increases bone formation in vivo
-
Cornish J, Callon KE, Naot D, Palmano KP, Banovic T, Bava U, Watson M, Lin JM, Tong PC, Chen Q, Chan VA, Reid HE, Fazzalari N, Baker HM, Baker EN, Haggarty NW, Grey AB, Reid IR: Lactoferrin is a potent regulator of bone cell activity and increases bone formation in vivo. Endocrinology 2004;145:4366-4374.
-
(2004)
Endocrinology
, vol.145
, pp. 4366-4374
-
-
Cornish, J.1
Callon, K.E.2
Naot, D.3
Palmano, K.P.4
Banovic, T.5
Bava, U.6
Watson, M.7
Lin, J.M.8
Tong, P.C.9
Chen, Q.10
Chan, V.A.11
Reid, H.E.12
Fazzalari, N.13
Baker, H.M.14
Baker, E.N.15
Haggarty, N.W.16
Grey, A.B.17
Reid, I.R.18
-
15
-
-
84887477844
-
Lactoferrin inhibits dexamethasoneinduced chondrocyte impairment from osteoarthritic cartilage through up-regulation of extracellular signal-regulated kinase 1/2 and suppression of fasl, fas, and caspase 3
-
Tu Y, Xue H, Francis W, Davies AP, Pallister I, Kanamarlapudi V, Xia Z: Lactoferrin inhibits dexamethasoneinduced chondrocyte impairment from osteoarthritic cartilage through up-regulation of extracellular signal-regulated kinase 1/2 and suppression of fasl, fas, and caspase 3. Biochem Biophys Res Commun 2013;441:249-255.
-
(2013)
Biochem Biophys Res Commun
, vol.441
, pp. 249-255
-
-
Tu, Y.1
Xue, H.2
Francis, W.3
Davies, A.P.4
Pallister, I.5
Kanamarlapudi, V.6
Xia, Z.7
-
16
-
-
84868029338
-
Bovine lactoferricin is anti-inflammatory and anticatabolic in human articular cartilage and synovium
-
Yan D, Chen D, Shen J, Xiao G, van Wijnen AJ, Im HJ: Bovine lactoferricin is anti-inflammatory and anticatabolic in human articular cartilage and synovium. J Cell Physiol 2013;228:447-456.
-
(2013)
J Cell Physiol
, vol.228
, pp. 447-456
-
-
Yan, D.1
Chen, D.2
Shen, J.3
Xiao, G.4
Van Wijnen, A.J.5
Im, H.J.6
-
17
-
-
84873524215
-
Bovine lactoferricin induces timp-3 via the erk1/2-sp1 axis in human articular chondrocytes
-
Yan D, Chen D, Hawse JR, van Wijnen AJ, Im HJ: Bovine lactoferricin induces timp-3 via the erk1/2-sp1 axis in human articular chondrocytes. Gene 2013;517:12-18.
-
(2013)
Gene
, vol.517
, pp. 12-18
-
-
Yan, D.1
Chen, D.2
Hawse, J.R.3
Van Wijnen, A.J.4
Im, H.J.5
-
18
-
-
84878702465
-
A method of isolating viable chondrocytes with proliferative capacity from cryopreserved human articular cartilage
-
Xia Z, Duan X, Murray D, Triffitt JT, Price AJ: A method of isolating viable chondrocytes with proliferative capacity from cryopreserved human articular cartilage. Cell Tissue Bank 2013;14:267-276.
-
(2013)
Cell Tissue Bank
, vol.14
, pp. 267-276
-
-
Xia, Z.1
Duan, X.2
Murray, D.3
Triffitt, J.T.4
Price, A.J.5
-
19
-
-
84888172899
-
Periodic mechanical stress stimulates the FAK mitogenic signal in rat chondrocytes through ERK1/2 activity
-
Liang W, Ren K, Liu F, Cui W, Wang Q, Chen Z, Fan W: Periodic mechanical stress stimulates the FAK mitogenic signal in rat chondrocytes through ERK1/2 activity. Cell Physiol Biochem. 2013;32:915-930.
-
(2013)
Cell Physiol Biochem.
, vol.32
, pp. 915-930
-
-
Liang, W.1
Ren, K.2
Liu, F.3
Cui, W.4
Wang, Q.5
Chen, Z.6
Fan, W.7
-
20
-
-
10744229945
-
Expression of the cartilage derived anti-angiogenic factor chondromodulin-i decreases in the early stage of experimental osteoarthritis
-
Hayami T, Funaki H, Yaoeda K, Mitui K, Yamagiwa H, Tokunaga K, Hatano H, Kondo J, Hiraki Y, Yamamoto T, Duong LT, Endo N: Expression of the cartilage derived anti-angiogenic factor chondromodulin-i decreases in the early stage of experimental osteoarthritis. J Rheumatol 2003;30:2207-2217.
-
(2003)
J Rheumatol
, vol.30
, pp. 2207-2217
-
-
Hayami, T.1
Funaki, H.2
Yaoeda, K.3
Mitui, K.4
Yamagiwa, H.5
Tokunaga, K.6
Hatano, H.7
Kondo, J.8
Hiraki, Y.9
Yamamoto, T.10
Duong, L.T.11
Endo, N.12
-
21
-
-
84885587761
-
Inhibition of histone deacetylases potentiates BMP9-induced osteogenic signaling in mouse mesenchymal stem cells
-
Hu N, Wang C, Liang X, Yin L, Luo X, Liu B, Zhang H, Shui W, Nan G, Wang N, Wu N, Chen X, He Y, Wen S, Deng F, Zhang H, Liao Z, Luu HH, Haydon RC, He TC, Huang W: Inhibition of histone deacetylases potentiates BMP9-induced osteogenic signaling in mouse mesenchymal stem cells. Cell Physiol Biochem. 2013;32:486-498.
-
(2013)
Cell Physiol Biochem.
, vol.32
, pp. 486-498
-
-
Hu, N.1
Wang, C.2
Liang, X.3
Yin, L.4
Luo, X.5
Liu, B.6
Zhang, H.7
Shui, W.8
Nan, G.9
Wang, N.10
Wu, N.11
Chen, X.12
He, Y.13
Wen, S.14
Deng, F.15
Zhang, H.16
Liao, Z.17
Luu, H.H.18
Haydon, R.C.19
He, T.C.20
Huang, W.21
more..
-
22
-
-
84863607237
-
Gemfibrozil, a lipid-lowering drug, upregulates il-1 receptor antagonist in mouse cortical neurons: Implications for neuronal self-defense
-
Corbett GT, Roy A, Pahan K: Gemfibrozil, a lipid-lowering drug, upregulates il-1 receptor antagonist in mouse cortical neurons: implications for neuronal self-defense. J Immunol 2012;189:1002-1013.
-
(2012)
J Immunol
, vol.189
, pp. 1002-1013
-
-
Corbett, G.T.1
Roy, A.2
Pahan, K.3
-
24
-
-
39649094726
-
Lithium inhibits smad3/4 transactivation via increased creb activity induced by enhanced pka and akt signaling
-
Liang MH, Wendland JR, Chuang DM: Lithium inhibits smad3/4 transactivation via increased creb activity induced by enhanced pka and akt signaling. Mol Cell Neurosci 2008;37:440-453.
-
(2008)
Mol Cell Neurosci
, vol.37
, pp. 440-453
-
-
Liang, M.H.1
Wendland, J.R.2
Chuang, D.M.3
-
25
-
-
0034564348
-
Osteoarthritis and cartilage: The role of cytokines
-
Goldring MB: Osteoarthritis and cartilage: the role of cytokines. Curr Rheumatol Rep 2000;2:459-465.
-
(2000)
Curr Rheumatol Rep
, vol.2
, pp. 459-465
-
-
Goldring, M.B.1
-
26
-
-
78650983649
-
Role of proinflammatory cytokines in the pathophysiology of osteoarthritis
-
Kapoor M, Martel-Pelletier J, Lajeunesse D, Pelletier JP, Fahmi H: Role of proinflammatory cytokines in the pathophysiology of osteoarthritis. Nat Rev Rheumatol 2011;7:33-42.
-
(2011)
Nat Rev Rheumatol
, vol.7
, pp. 33-42
-
-
Kapoor, M.1
Martel-Pelletier, J.2
Lajeunesse, D.3
Pelletier, J.P.4
Fahmi, H.5
-
27
-
-
84900890456
-
Regulating chondrogenesis of human mesenchymal stromal cells with a retinoic Acid receptor-Beta inhibitor: Differential sensitivity of chondral versus osteochondral development
-
Diederichs S, Zachert K, Raiss P, Richter W: Regulating chondrogenesis of human mesenchymal stromal cells with a retinoic Acid receptor-Beta inhibitor: differential sensitivity of chondral versus osteochondral development. Cell Physiol Biochem. 2014;33:1607-1619.
-
(2014)
Cell Physiol Biochem.
, vol.33
, pp. 1607-1619
-
-
Diederichs, S.1
Zachert, K.2
Raiss, P.3
Richter, W.4
-
28
-
-
0034351876
-
Interleukin-1beta induces different gene expression of stromelysin, aggrecan and tumor-necrosis-factor-stimulated gene 6 in human osteoarthritic chondrocytes in vitro
-
Stove J, Huch K, Gunther KP, Scharf HP: Interleukin-1beta induces different gene expression of stromelysin, aggrecan and tumor-necrosis-factor-stimulated gene 6 in human osteoarthritic chondrocytes in vitro. Pathobiology 2000;68:144-149.
-
(2000)
Pathobiology
, vol.68
, pp. 144-149
-
-
Stove, J.1
Huch, K.2
Gunther, K.P.3
Scharf, H.P.4
-
29
-
-
84893673065
-
Berberine ameliorates cartilage degeneration in interleukin-1beta-stimulated rat chondrocytes and in a rat model of osteoarthritis via akt signalling
-
Zhao H, Zhang T, Xia C, Shi L, Wang S, Zheng X, Hu T, Zhang B: Berberine ameliorates cartilage degeneration in interleukin-1beta-stimulated rat chondrocytes and in a rat model of osteoarthritis via akt signalling. J Cell Mol Med 2014;18:283-292.
-
(2014)
J Cell Mol Med
, vol.18
, pp. 283-292
-
-
Zhao, H.1
Zhang, T.2
Xia, C.3
Shi, L.4
Wang, S.5
Zheng, X.6
Hu, T.7
Zhang, B.8
-
30
-
-
0032829090
-
P300 and cbp: Partners for life and death
-
Giordano A, Avantaggiati ML: P300 and cbp: partners for life and death. J Cell Physiol 1999;181:218-230.
-
(1999)
J Cell Physiol
, vol.181
, pp. 218-230
-
-
Giordano, A.1
Avantaggiati, M.L.2
-
31
-
-
0035853705
-
Pthrp modulates chondrocyte differentiation through ap-1 and creb signaling
-
Ionescu AM, Schwarz EM, Vinson C, Puzas JE, Rosier R, Reynolds PR, O'Keefe RJ: Pthrp modulates chondrocyte differentiation through ap-1 and creb signaling. J Biol Chem 2001;276:11639-11647.
-
(2001)
J Biol Chem
, vol.276
, pp. 11639-11647
-
-
Ionescu, A.M.1
Schwarz, E.M.2
Vinson, C.3
Puzas, J.E.4
Rosier, R.5
Reynolds, P.R.6
O'Keefe, R.J.7
-
32
-
-
0036346580
-
Protein phosphatase 2a is involved in the regulation of protein kinase a signaling pathway during in vitro chondrogenesis
-
Zakany R, Szucs K, Bako E, Felszeghy S, Czifra G, Biro T, Modis L, Gergely P: Protein phosphatase 2a is involved in the regulation of protein kinase a signaling pathway during in vitro chondrogenesis. Exp Cell Res 2002;275:1-8.
-
(2002)
Exp Cell Res
, vol.275
, pp. 1-8
-
-
Zakany, R.1
Szucs, K.2
Bako, E.3
Felszeghy, S.4
Czifra, G.5
Biro, T.6
Modis, L.7
Gergely, P.8
-
33
-
-
0035093406
-
The creb family of activators is required for endochondral bone development
-
Long F, Schipani E, Asahara H, Kronenberg H, Montminy M: The creb family of activators is required for endochondral bone development. Development 2001;128:541-550.
-
(2001)
Development
, vol.128
, pp. 541-550
-
-
Long, F.1
Schipani, E.2
Asahara, H.3
Kronenberg, H.4
Montminy, M.5
-
34
-
-
34247869654
-
Activating transcription factor 2 controls bcl-2 promoter activity in growth plate chondrocytes
-
Ma Q, Li X, Vale-Cruz D, Brown ML, Beier F, LuValle P: Activating transcription factor 2 controls bcl-2 promoter activity in growth plate chondrocytes. J Cell Biochem 2007;101:477-487.
-
(2007)
J Cell Biochem
, vol.101
, pp. 477-487
-
-
Ma, Q.1
Li, X.2
Vale-Cruz, D.3
Brown, M.L.4
Beier, F.5
Luvalle, P.6
-
35
-
-
84923116267
-
Shikonin protects chondrocytes from interleukin-1betainduced apoptosis by regulating pi3k/akt signaling pathway
-
Wang L, Gai P, Xu R, Zheng Y, Lv S, Li Y, Liu S: Shikonin protects chondrocytes from interleukin-1betainduced apoptosis by regulating pi3k/akt signaling pathway. Int J Clin Exp Pathol 2015;8:298-308.
-
(2015)
Int J Clin Exp Pathol
, vol.8
, pp. 298-308
-
-
Wang, L.1
Gai, P.2
Xu, R.3
Zheng, Y.4
Lv, S.5
Li, Y.6
Liu, S.7
-
36
-
-
84905194694
-
Protection of ginsenoside rg1 on chondrocyte from il-1beta-induced mitochondriaactivated apoptosis through pi3k/akt signaling
-
Huang Y, Wu D, Fan W: Protection of ginsenoside rg1 on chondrocyte from il-1beta-induced mitochondriaactivated apoptosis through pi3k/akt signaling. Mol Cell Biochem 2014;392:249-257.
-
(2014)
Mol Cell Biochem
, vol.392
, pp. 249-257
-
-
Huang, Y.1
Wu, D.2
Fan, W.3
-
37
-
-
84899978192
-
The nitric oxide-cgkii system relays death and survival signals during embryonic retinal development via akt-induced creb1 activation
-
Socodato R, Brito R, Portugal CC, de Oliveira NA, Calaza KC, Paes-de-Carvalho R: The nitric oxide-cgkii system relays death and survival signals during embryonic retinal development via akt-induced creb1 activation. Cell Death Differ 2014;21:915-928.
-
(2014)
Cell Death Differ
, vol.21
, pp. 915-928
-
-
Socodato, R.1
Brito, R.2
Portugal, C.C.3
De Oliveira, N.A.4
Calaza, K.C.5
Paes-De-Carvalho, R.6
-
38
-
-
84867029736
-
Resveratrol prevents ca1 neurons against ischemic injury by parallel modulation of both gsk-3beta and creb through pi3-k/akt pathways
-
Simao F, Matte A, Pagnussat AS, Netto CA, Salbego CG: Resveratrol prevents ca1 neurons against ischemic injury by parallel modulation of both gsk-3beta and creb through pi3-k/akt pathways. Eur J Neurosci 2012;36:2899-2905.
-
(2012)
Eur J Neurosci
, vol.36
, pp. 2899-2905
-
-
Simao, F.1
Matte, A.2
Pagnussat, A.S.3
Netto, C.A.4
Salbego, C.G.5
|