-
1
-
-
26444615136
-
The effect of IL-1beta on the expression of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in human chondrocytes
-
DOI 10.1016/j.lfs.2005.05.052, PII S0024320505005813
-
Aida Y, Maeno M, Suzuki N, Shiratsuchi H, Motohashi M, Matsumura H (2005) The effect of IL-1beta on the expression of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in human chondrocytes. Life Sci 77:3210-3221. doi:10.1016/j.lfs.2005.05.052 (Pubitemid 41433321)
-
(2005)
Life Sciences
, vol.77
, Issue.25
, pp. 3210-3221
-
-
Aida, Y.1
Maeno, M.2
Suzuki, N.3
Shiratsuchi, H.4
Motohashi, M.5
Matsumura, H.6
-
2
-
-
52949117087
-
The effect of hyaluronic acid on IL-1beta-induced chondrocyte apoptosis in a rat model of osteoarthritis
-
doi:10.1002/jor.20683
-
Zhou PH, Liu SQ, Peng H (2008) The effect of hyaluronic acid on IL-1beta-induced chondrocyte apoptosis in a rat model of osteoarthritis. J Orthop Res 26:1643-1648. doi:10.1002/jor.20683
-
(2008)
J Orthop Res
, vol.26
, pp. 1643-1648
-
-
Zhou, P.H.1
Liu, S.Q.2
Peng, H.3
-
3
-
-
33847194975
-
Cell death and apoptosis in osteoarthritic cartilage
-
Kim HA, Blanco FJ (2007) Cell death and apoptosis in osteoarthritic cartilage. Curr Drug Targets 8:333-345
-
(2007)
Curr Drug Targets
, vol.8
, pp. 333-345
-
-
Kim, H.A.1
Blanco, F.J.2
-
4
-
-
54249096028
-
Caspases in apoptosis and beyond
-
doi:10.1038/onc.2008.297
-
Li J, Yuan J (2008) Caspases in apoptosis and beyond. Oncogene 27:6194-6206. doi:10.1038/onc.2008.297
-
(2008)
Oncogene
, vol.27
, pp. 6194-6206
-
-
Li, J.1
Yuan, J.2
-
5
-
-
78049390935
-
The protective effect of tetramethylpyrazine on cartilage explants and chondrocytes
-
doi:10.1016/j.jep.2010.08.020
-
Ju XD, Deng M, Ao YF, Yu CL, Wang JQ, Yu JK, Cui GQ, Hu YL (2010) The protective effect of tetramethylpyrazine on cartilage explants and chondrocytes. J Ethnopharmacol 132:414-420. doi:10.1016/j.jep.2010.08.020
-
(2010)
J Ethnopharmacol
, vol.132
, pp. 414-420
-
-
Ju, X.D.1
Deng, M.2
Ao, Y.F.3
Yu, C.L.4
Wang, J.Q.5
Yu, J.K.6
Cui, G.Q.7
Hu, Y.L.8
-
6
-
-
0035213530
-
Bax and other pro-apoptotic Bcl-2 family "killer-proteins" and their victim the mitochondrion
-
doi:10.1007/s00441-001-0472-0
-
Antonsson B (2001) Bax and other pro-apoptotic Bcl-2 family "killer-proteins" and their victim the mitochondrion. Cell Tissue Res 306:347-361. doi:10.1007/s00441-001-0472-0
-
(2001)
Cell Tissue Res
, vol.306
, pp. 347-361
-
-
Antonsson, B.1
-
8
-
-
45349094984
-
Mitochondrial dynamics and apoptosis
-
DOI 10.1101/gad.1658508
-
Suen DF, Norris KL, Youle RJ (2008) Mitochondrial dynamics and apoptosis. Genes Dev 22:1577-1590. doi:10.1101/gad.1658508 (Pubitemid 351846838)
-
(2008)
Genes and Development
, vol.22
, Issue.12
, pp. 1577-1590
-
-
Suen, D.-F.1
Norris, K.L.2
Youle, R.J.3
-
9
-
-
83355173227
-
IGF-1 and PDGF-bb suppress IL-1beta-induced cartilage degradation through down-regulation of NF-kappaB signaling: Involvement of Src/PI-3 K/AKT pathway
-
doi:10.1371/journal.pone.0028663
-
Montaseri A, Busch F, Mobasheri A, Buhrmann C, Aldinger C, Rad JS, Shakibaei M (2011) IGF-1 and PDGF-bb suppress IL-1beta-induced cartilage degradation through down-regulation of NF-kappaB signaling: involvement of Src/PI-3 K/AKT pathway. PLoS One 6:e28663. doi:10.1371/journal.pone.0028663
-
(2011)
PLoS One
, vol.6
-
-
Montaseri, A.1
Busch, F.2
Mobasheri, A.3
Buhrmann, C.4
Aldinger, C.5
Rad, J.S.6
Shakibaei, M.7
-
10
-
-
44049102307
-
A purified extract from clematis mandshurica prevents adenoviral-TRAIL induced apoptosis on rat articular chondrocytes
-
DOI 10.1142/S0192415X08005850, PII S0192415X08005850
-
Lee SW, Lee HJ, Moon JB, Choi SM, Kim DK, Kim IR, Choi WC, Park BS (2008) Purified extract from Clematis mandshurica prevents adenoviral-TRAIL induced apoptosis on rat articular chondrocytes. Am J Chin Med 36:399-410. doi:10.1142/s0192415x08005850 (Pubitemid 351712444)
-
(2008)
American Journal of Chinese Medicine
, vol.36
, Issue.2
, pp. 399-410
-
-
Lee, S.W.1
Lee, H.J.2
Moon, J.B.3
Choi, S.M.4
Kim, D.K.5
Kim, I.R.6
Choi, W.C.7
Park, B.S.8
-
11
-
-
54749095969
-
4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: The protective role of glutathione-S-transferase
-
doi:10.1186/ar2503
-
Vaillancourt F, Fahmi H, Shi Q, Lavigne P, Ranger P, Fernandes JC, Benderdour M (2008) 4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase. Arthritis Res Ther 10:R107. doi:10.1186/ar2503
-
(2008)
Arthritis Res Ther
, vol.10
-
-
Vaillancourt, F.1
Fahmi, H.2
Shi, Q.3
Lavigne, P.4
Ranger, P.5
Fernandes, J.C.6
Benderdour, M.7
-
12
-
-
72149127646
-
Ginsenoside Rg1 protects against 6-OHDA-induced toxicity in MES23.5 cells via Akt and ERK signaling pathways
-
doi:10.1016/j.jep.2009.09.038
-
Ge KL, Chen WF, Xie JX, Wong MS (2010) Ginsenoside Rg1 protects against 6-OHDA-induced toxicity in MES23.5 cells via Akt and ERK signaling pathways. J Ethnopharmacol 127:118-123. doi:10.1016/j.jep.2009.09.038
-
(2010)
J Ethnopharmacol
, vol.127
, pp. 118-123
-
-
Ge, K.L.1
Chen, W.F.2
Xie, J.X.3
Wong, M.S.4
-
13
-
-
78650415275
-
Ginsenoside Rg1 protects against hydrogen peroxide-induced cell death in PC12 cells via inhibiting NF-kappaB activation
-
doi:10.1016/j.neuint.2010.11.004
-
Liu Q, Kou JP, Yu BY (2011) Ginsenoside Rg1 protects against hydrogen peroxide-induced cell death in PC12 cells via inhibiting NF-kappaB activation. Neurochem Int 58:119-125. doi:10.1016/j.neuint.2010.11.004
-
(2011)
Neurochem Int
, vol.58
, pp. 119-125
-
-
Liu, Q.1
Kou, J.P.2
Yu, B.Y.3
-
14
-
-
84862007373
-
Ginsenoside Rg1 protection against beta-amyloid peptide-induced neuronal apoptosis via estrogen receptor alpha and glucocorticoid receptor-dependent anti-protein nitration pathway
-
doi:10.1016/j.neuropharm.2012.04.005
-
Wu J, Pan Z, Wang Z, Zhu W, Shen Y, Cui R, Lin J, Yu H, Wang Q, Qian J, Yu Y, Zhu D, Lou Y (2012) Ginsenoside Rg1 protection against beta-amyloid peptide-induced neuronal apoptosis via estrogen receptor alpha and glucocorticoid receptor-dependent anti-protein nitration pathway. Neuropharmacology 63:349-361. doi:10.1016/j.neuropharm.2012.04.005
-
(2012)
Neuropharmacology
, vol.63
, pp. 349-361
-
-
Wu, J.1
Pan, Z.2
Wang, Z.3
Zhu, W.4
Shen, Y.5
Cui, R.6
Lin, J.7
Yu, H.8
Wang, Q.9
Qian, J.10
Yu, Y.11
Zhu, D.12
Lou, Y.13
-
15
-
-
33846890205
-
Neuroprotective effects of ginsenoside-Rg1 in primary nigral neurons against rotenone toxicity
-
DOI 10.1016/j.neuropharm.2006.10.001, PII S0028390806003467
-
Leung KW, Yung KK, Mak NK, Chan YS, Fan TP, Wong RN (2007) Neuroprotective effects of ginsenoside-Rg1 in primary nigral neurons against rotenone toxicity. Neuropharmacology 52:827-835. doi:10.1016/j.neuropharm.2006. 10.001 (Pubitemid 46227475)
-
(2007)
Neuropharmacology
, vol.52
, Issue.3
, pp. 827-835
-
-
Leung, K.W.1
Yung, K.K.L.2
Mak, N.K.3
Chan, Y.S.4
Fan, T.P.5
Wong, R.N.S.6
-
16
-
-
67650681776
-
Panax ginseng C.A. Meyer modulates the levels of MMP3 in S12 murine articular cartilage cell line
-
doi:10.1016/j.jep.2009.05.036
-
Shin JS, Park N, Ra J, Kim Y, Shin M, Hong M, Kim SH, Kwon HJ, Hong SP, Kim J, Bae H (2009) Panax ginseng C.A. Meyer modulates the levels of MMP3 in S12 murine articular cartilage cell line. J Ethnopharmacol 124:397-403. doi:10.1016/j.jep.2009.05.036
-
(2009)
J Ethnopharmacol
, vol.124
, pp. 397-403
-
-
Shin, J.S.1
Park, N.2
Ra, J.3
Kim, Y.4
Shin, M.5
Hong, M.6
Kim, S.H.7
Kwon, H.J.8
Hong, S.P.9
Kim, J.10
Bae, H.11
-
17
-
-
84872496291
-
Protective effects of ginsenoside Rg3 on human osteoarthritic chondrocytes
-
doi:10.1007/s10165-012-0635-8
-
So MW, Lee EJ, Lee HS, Koo BS, Kim YG, Lee CK, Yoo B (2013) Protective effects of ginsenoside Rg3 on human osteoarthritic chondrocytes. Mod Rheumatol 23:104-111. doi:10.1007/s10165-012-0635-8
-
(2013)
Mod Rheumatol
, vol.23
, pp. 104-111
-
-
So, M.W.1
Lee, E.J.2
Lee, H.S.3
Koo, B.S.4
Kim, Y.G.5
Lee, C.K.6
Yoo, B.7
-
18
-
-
84860138468
-
The protective effects of ginsenoside Rg1 against hypertension target-organ damage in spontaneously hypertensive rats
-
doi:10.1186/1472-6882-12-53
-
Chen H, Yin J, Deng Y, Yang M, Xu L, Teng F, Li D, Cheng Y, Liu S, Wang D, Zhang T, Wu W, Liu X, Guan S, Jiang B, Guo D (2012) The protective effects of ginsenoside Rg1 against hypertension target-organ damage in spontaneously hypertensive rats. BMC Complement Altern Med 12:53. doi:10.1186/1472-6882-12-53
-
(2012)
BMC Complement Altern Med
, vol.12
, pp. 53
-
-
Chen, H.1
Yin, J.2
Deng, Y.3
Yang, M.4
Xu, L.5
Teng, F.6
Li, D.7
Cheng, Y.8
Liu, S.9
Wang, D.10
Zhang, T.11
Wu, W.12
Liu, X.13
Guan, S.14
Jiang, B.15
Guo, D.16
-
19
-
-
76449099412
-
Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: Inhibition of IL-1beta-induced NF-kappaB-mediated inflammation and apoptosis
-
doi:10.1186/ar2850
-
Csaki C, Mobasheri A, Shakibaei M (2009) Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1beta-induced NF-kappaB-mediated inflammation and apoptosis. Arthritis Res Ther 11:R165. doi:10.1186/ar2850
-
(2009)
Arthritis Res Ther
, vol.11
-
-
Csaki, C.1
Mobasheri, A.2
Shakibaei, M.3
-
20
-
-
0028984979
-
Ginsenoside Rg1 modulates ingestive behavior and thermal response induced by interleukin-1 beta in rats
-
Kang M, Yoshimatsu H, Oohara A, Kurokawa M, Ogawa R, Sakata T (1995) Ginsenoside Rg1 modulates ingestive behavior and thermal response induced by interleukin-1 beta in rats. Physiol Behav 57:393-396
-
(1995)
Physiol Behav
, vol.57
, pp. 393-396
-
-
Kang, M.1
Yoshimatsu, H.2
Oohara, A.3
Kurokawa, M.4
Ogawa, R.5
Sakata, T.6
-
21
-
-
46249089246
-
Intracerebroventricular ginsenosides are antinociceptive in proinflammatory cytokine-induced pain behaviors of mice
-
doi:10.1007/s12272-001-1165-x
-
Seo YJ, Kwon MS, Choi HW, Jang JE, Lee JK, Sun Y, Jung JS, Park SH, Suh HW (2008) Intracerebroventricular ginsenosides are antinociceptive in proinflammatory cytokine-induced pain behaviors of mice. Arch Pharm Res 31:364-369. doi:10.1007/s12272-001-1165-x
-
(2008)
Arch Pharm Res
, vol.31
, pp. 364-369
-
-
Seo, Y.J.1
Kwon, M.S.2
Choi, H.W.3
Jang, J.E.4
Lee, J.K.5
Sun, Y.6
Jung, J.S.7
Park, S.H.8
Suh, H.W.9
-
22
-
-
79955053353
-
Ginsenoside Rg1 protects primary cultured rat hippocampal neurons from cell apoptosis induced by beta-amyloid protein
-
doi:10.3109/13880209.2010.521514
-
Gong L, Li SL, Li H, Zhang L (2011) Ginsenoside Rg1 protects primary cultured rat hippocampal neurons from cell apoptosis induced by beta-amyloid protein. Pharm Biol 49:501-507. doi:10.3109/13880209.2010.521514
-
(2011)
Pharm Biol
, vol.49
, pp. 501-507
-
-
Gong, L.1
Li, S.L.2
Li, H.3
Zhang, L.4
-
23
-
-
84876943372
-
Activating glucocorticoid receptor-ERK signaling pathway contributes to ginsenoside Rg1 protection against beta-amyloid peptide-induced human endothelial cells apoptosis
-
doi:10.1016/j.jep.2013.03.039
-
Yan J, Liu Q, Dou Y, Hsieh Y, Liu Y, Tao R, Zhu D, Lou Y (2013) Activating glucocorticoid receptor-ERK signaling pathway contributes to ginsenoside Rg1 protection against beta-amyloid peptide-induced human endothelial cells apoptosis. J Ethnopharmacol 147:456-466. doi:10.1016/j.jep. 2013.03.039
-
(2013)
J Ethnopharmacol
, vol.147
, pp. 456-466
-
-
Yan, J.1
Liu, Q.2
Dou, Y.3
Hsieh, Y.4
Liu, Y.5
Tao, R.6
Zhu, D.7
Lou, Y.8
-
24
-
-
77952705182
-
Biology and pathology of Rho GTPase, PI-3 kinase-Akt, and MAP kinase signaling pathways in chondrocytes
-
doi:10.1002/jcb.22604
-
Beier F, Loeser RF (2010) Biology and pathology of Rho GTPase, PI-3 kinase-Akt, and MAP kinase signaling pathways in chondrocytes. J Cell Biochem 110:573-580. doi:10.1002/jcb.22604
-
(2010)
J Cell Biochem
, vol.110
, pp. 573-580
-
-
Beier, F.1
Loeser, R.F.2
-
25
-
-
0141592429
-
Signaling mechanisms leading to the regulation of differentiation and apoptosis of articular chondrocytes by insulin-like growth factor-1
-
doi:10.1074/jbc.M304857200
-
Oh CD, Chun JS (2003) Signaling mechanisms leading to the regulation of differentiation and apoptosis of articular chondrocytes by insulin-like growth factor-1. J Biol Chem 278:36563-36571. doi:10.1074/jbc.M304857200
-
(2003)
J Biol Chem
, vol.278
, pp. 36563-36571
-
-
Oh, C.D.1
Chun, J.S.2
-
26
-
-
0242522206
-
Regulation of apoptosis by Bcl-2 family proteins
-
Burlacu A (2003) Regulation of apoptosis by Bcl-2 family proteins. J Cell Mol Med 7:249-257
-
(2003)
J Cell Mol Med
, vol.7
, pp. 249-257
-
-
Burlacu, A.1
-
27
-
-
71549172179
-
PI-3-K and AKT: Onto the mitochondria
-
doi:10.1016/j.addr.2009.07.017
-
Stiles BL (2009) PI-3-K and AKT: onto the mitochondria. Adv Drug Deliv Rev 61:1276-1282. doi:10.1016/j.addr.2009.07.017
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 1276-1282
-
-
Stiles, B.L.1
-
28
-
-
33748633513
-
20(S)-Ginsenoside Rg3 prevents endothelial cell apoptosis via inhibition of a mitochondrial caspase pathway
-
DOI 10.1016/j.bbrc.2006.08.129, PII S0006291X06019383
-
Min JK, Kim JH, Cho YL, Maeng YS, Lee SJ, Pyun BJ, Kim YM, Park JH, Kwon YG (2006) 20(S)-Ginsenoside Rg3 prevents endothelial cell apoptosis via inhibition of a mitochondrial caspase pathway. Biochem Biophys Res Commun 349:987-994. doi:10.1016/j.bbrc.2006.08.129 (Pubitemid 44380196)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.349
, Issue.3
, pp. 987-994
-
-
Min, J.-K.1
Kim, J.-H.2
Cho, Y.-L.3
Maeng, Y.-S.4
Lee, S.-J.5
Pyun, B.-J.6
Kim, Y.-M.7
Park, J.H.8
Kwon, Y.-G.9
-
29
-
-
84859909950
-
17beta-Oestradiol inhibits doxorubicin-induced apoptosis via block of the volume-sensitive Cl(-) current in rabbit articular chondrocytes
-
doi:10.1111/j.1476-5381.2011.01802.x
-
Kumagai K, Imai S, Toyoda F, Okumura N, Isoya E, Matsuura H, Matsusue Y (2012) 17beta-Oestradiol inhibits doxorubicin-induced apoptosis via block of the volume-sensitive Cl(-) current in rabbit articular chondrocytes. Br J Pharmacol 166:702-720. doi:10.1111/j.1476-5381.2011.01802.x
-
(2012)
Br J Pharmacol
, vol.166
, pp. 702-720
-
-
Kumagai, K.1
Imai, S.2
Toyoda, F.3
Okumura, N.4
Isoya, E.5
Matsuura, H.6
Matsusue, Y.7
-
30
-
-
78650834899
-
17beta-Estradiol regulates rat growth plate chondrocyte apoptosis through a mitochondrial pathway not involving nitric oxide or MAPKs
-
doi:10.1210/en.2010-0509
-
Zhong M, Carney DH, Boyan BD, Schwartz Z (2011) 17beta-Estradiol regulates rat growth plate chondrocyte apoptosis through a mitochondrial pathway not involving nitric oxide or MAPKs. Endocrinology 152:82-92. doi:10.1210/en.2010-0509
-
(2011)
Endocrinology
, vol.152
, pp. 82-92
-
-
Zhong, M.1
Carney, D.H.2
Boyan, B.D.3
Schwartz, Z.4
-
31
-
-
84867820015
-
Ginsenoside Rb1 Prevents MPP(?)-Induced Apoptosis in PC12 Cells by Stimulating Estrogen Receptors with Consequent Activation of ERK1/2, Akt and Inhibition of SAPK/JNK, p38 MAPK
-
doi:10.1155/2012/693717
-
Hashimoto R, Yu J, Koizumi H, Ouchi Y, Okabe T (2012) Ginsenoside Rb1 Prevents MPP(?)-Induced Apoptosis in PC12 Cells by Stimulating Estrogen Receptors with Consequent Activation of ERK1/2, Akt and Inhibition of SAPK/JNK, p38 MAPK. Evid Based Complement Alternat Med 2012:693717. doi:10.1155/2012/ 693717
-
(2012)
Evid Based Complement Alternat Med
, vol.2012
, pp. 693717
-
-
Hashimoto, R.1
Yu, J.2
Koizumi, H.3
Ouchi, Y.4
Okabe, T.5
-
32
-
-
79960975877
-
Roles of inflammatory and anabolic cytokines in cartilage metabolism: Signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis
-
Goldring MB, Otero M, Plumb DA, Dragomir C, Favero M, El Hachem K, Hashimoto K, Roach HI, Olivotto E, Borzi RM, Marcu KB (2011) Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis. Eur Cell Mater 21:202-220
-
(2011)
Eur Cell Mater
, vol.21
, pp. 202-220
-
-
Goldring, M.B.1
Otero, M.2
Plumb, D.A.3
Dragomir, C.4
Favero, M.5
El Hachem, K.6
Hashimoto, K.7
Roach, H.I.8
Olivotto, E.9
Borzi, R.M.10
Marcu, K.B.11
-
33
-
-
84863310849
-
Requirement of the phosphatidylinositol 3-kinase/Akt signaling pathway for the effect of nicotine on interleukin-1beta-induced chondrocyte apoptosis in a rat model of osteoarthritis
-
doi:10.1016/j.bbrc.2012.06.045
-
Zheng X, Xia C, Chen Z, Huang J, Gao F, Li G, Zhang B (2012) Requirement of the phosphatidylinositol 3-kinase/Akt signaling pathway for the effect of nicotine on interleukin-1beta-induced chondrocyte apoptosis in a rat model of osteoarthritis. Biochem Biophys Res Commun 423:606-612. doi:10.1016/j.bbrc.2012. 06.045
-
(2012)
Biochem Biophys Res Commun
, vol.423
, pp. 606-612
-
-
Zheng, X.1
Xia, C.2
Chen, Z.3
Huang, J.4
Gao, F.5
Li, G.6
Zhang, B.7
-
34
-
-
69249148258
-
Ginsenoside Rg1 protects rat cardiomyocyte from hypoxia/reoxygenation oxidative injury via antioxidant and intracellular calcium homeostasis
-
doi:10.1002/jcb.22233
-
Zhu D, Wu L, Li CR, Wang XW, Ma YJ, Zhong ZY, Zhao HB, Cui J, Xun SF, Huang XL, Zhou Z, Wang SQ (2009) Ginsenoside Rg1 protects rat cardiomyocyte from hypoxia/reoxygenation oxidative injury via antioxidant and intracellular calcium homeostasis. J Cell Biochem 108:117-124. doi:10.1002/jcb.22233
-
(2009)
J Cell Biochem
, vol.108
, pp. 117-124
-
-
Zhu, D.1
Wu, L.2
Li, C.R.3
Wang, X.W.4
Ma, Y.J.5
Zhong, Z.Y.6
Zhao, H.B.7
Cui, J.8
Xun, S.F.9
Huang, X.L.10
Zhou, Z.11
Wang, S.Q.12
|