Shikonin protects chondrocytes from interleukin-1beta-induced apoptosis by regulating PI3K/Akt signaling pathway

International Journal of Clinical and Experimental Pathology

Volumn 8, Issue 1, 2015, Pages 298-308

  Wang, Leisheng ^a,b   Gai, Pengzhou ^c   Xu, Renguo ^d   Zheng, Yanpin ^a   Lv, Shiqiao ^b   Li, Yu ^b   Liu, Shaoxian ^b  

^a SHANDONG UNIVERSITY   (China)

^b YANTAISHAN HOSPITAL   (China)

^c YANTAI YUHUANGDING HOSPITAL   (China)

^d Department of Orthopedics Yantai Economic and Technology Development Area Hospital   (China)

Author keywords

Apoptosis; Chondrocytes; IL 1; Osteoarthritis; PI3K Akt signaling; Shikonin

Indexed keywords

NAPHTHOQUINONE; NONSTEROID ANTIINFLAMMATORY AGENT; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SHIKONIN;

ANIMAL; APOPTOSIS; CARTILAGE CELL; CELL CULTURE; CELL SURVIVAL; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; MALE; METABOLISM; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; BLOTTING, WESTERN; CELL SURVIVAL; CELLS, CULTURED; CHONDROCYTES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; MALE; NAPHTHOQUINONES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 84923116267     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article

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