Regulating chondrogenesis of human mesenchymal stromal cells with a retinoic acid receptor-beta inhibitor: Differential sensitivity of chondral versus osteochondral development

Cellular Physiology and Biochemistry

Volumn 33, Issue 6, 2014, Pages 1607-1619

  Diederichs, Solvig ^a   Zachert, Kerstin ^a   Raiss, Patric ^a   Richter, Wiltrud ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

Chondrogenic differentiation; Endochondral differentiation; Human mesenchymal stromal cells; Retinole acid receptor antagonist

Indexed keywords

4 (7,8,9,10 TETRAHYDRO 5,7,7,10,10 PENTAMETHYL 5H BENZO[E]NAPHTHO[2,3 B][1,4]DIAZEPIN 13 YL)BENZOIC ACID; ALKALINE PHOSPHATASE; COLLAGEN TYPE 1; COLLAGEN TYPE 10; COLLAGEN TYPE 2; COLLAGENASE 3; GLYCOSAMINOGLYCAN; RETINOIC ACID RECEPTOR; RETINOIC ACID RECEPTOR BETA ANTAGONIST; SONIC HEDGEHOG PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; BMP4 PROTEIN, HUMAN; BONE MORPHOGENETIC PROTEIN 4; COL2A1 PROTEIN, HUMAN; DIBENZAZEPINE DERIVATIVE; LE 135; RETINOIC ACID RECEPTOR BETA; COLLAGEN TYPE 9; RECEPTOR BLOCKING AGENT; RETINOIC ACID RECEPTOR BETA INHIBITOR;

ADIPOSE TISSUE; ADULT; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; BONE MARROW; CARTILAGE CELL; CELL DIFFERENTIATION; CHONDROGENESIS; CLINICAL ASSESSMENT; CONTROLLED STUDY; DRUG EFFECT; DRUG SYNTHESIS; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HYALINE CARTILAGE; IN VITRO STUDY; MESENCHYMAL STROMA CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; ADOLESCENT; AGED; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL PROLIFERATION; DRUG EFFECTS; GENETICS; METABOLISM; MIDDLE AGED; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; YOUNG ADULT; ADIPOSE DERIVED STEM CELL; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CYTOTOXICITY TEST; STEM CELL CULTURE;

ADOLESCENT; ADULT; AGED; ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 4; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CHONDROCYTES; CHONDROGENESIS; COLLAGEN TYPE II; DIBENZAZEPINES; FEMALE; GENE EXPRESSION; GLYCOSAMINOGLYCANS; HEDGEHOG PROTEINS; HUMANS; MATRIX METALLOPROTEINASE 13; MESENCHYMAL STROMAL CELLS; MIDDLE AGED; RECEPTORS, RETINOIC ACID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; YOUNG ADULT;

EID: 84900890456     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000358723     Document Type: Article

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