메뉴 건너뛰기




Volumn 34, Issue 27, 2015, Pages 3536-3546

Kaposi sarcoma-associated herpesvirus promotes tumorigenesis by modulating the Hippo pathway

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR YAP; UNCLASSIFIED DRUG; HIPPO PROTEIN, HUMAN; NUCLEAR PROTEIN; PROTEIN SERINE THREONINE KINASE; TAZ PROTEIN, HUMAN; YY1AP1 PROTEIN, HUMAN;

EID: 84939417563     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2014.281     Document Type: Article
Times cited : (63)

References (67)
  • 1
    • 76849087997 scopus 로고    scopus 로고
    • Kaposi sarcoma-associated herpesvirus (KSHV): Molecular biology and oncogenesis
    • Wen KW, Damania B. Kaposi sarcoma-associated herpesvirus (KSHV): molecular biology and oncogenesis. Cancer Lett 2010; 289: 140-150.
    • (2010) Cancer Lett , vol.289 , pp. 140-150
    • Wen, K.W.1    Damania, B.2
  • 2
    • 0032490978 scopus 로고    scopus 로고
    • Transformation of primary human endothelial cells by Kaposi's sarcoma-associated herpesvirus
    • Flore O, Rafii S, Ely S, O'Leary JJ, Hyjek EM, Cesarman E. Transformation of primary human endothelial cells by Kaposi's sarcoma-associated herpesvirus. Nature 1998; 394: 588-592.
    • (1998) Nature , vol.394 , pp. 588-592
    • Flore, O.1    Rafii, S.2    Ely, S.3    O'Leary, J.J.4    Hyjek, E.M.5    Cesarman, E.6
  • 3
    • 0034232208 scopus 로고    scopus 로고
    • Kaposi's sarcoma in HIV-infected patients: Treatment options
    • Hermans P. Kaposi's sarcoma in HIV-infected patients: treatment options. HIV Med 2000; 1: 137-142.
    • (2000) HIV Med , vol.1 , pp. 137-142
    • Hermans, P.1
  • 4
    • 77957121811 scopus 로고    scopus 로고
    • Kaposi's sarcoma and its associated herpesvirus
    • Mesri EA, Cesarman E, Boshoff C. Kaposi's sarcoma and its associated herpesvirus. Nat Rev Cancer 2010; 10: 707-719.
    • (2010) Nat Rev Cancer , vol.10 , pp. 707-719
    • Mesri, E.A.1    Cesarman, E.2    Boshoff, C.3
  • 5
    • 33645744610 scopus 로고    scopus 로고
    • KSHV infection and the pathogenesis of Kaposi's sarcoma
    • Ganem D. KSHV infection and the pathogenesis of Kaposi's sarcoma. Annu Rev Pathol 2006; 1: 273-296.
    • (2006) Annu Rev Pathol , vol.1 , pp. 273-296
    • Ganem, D.1
  • 6
    • 0028588064 scopus 로고
    • Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma
    • Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM et al. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 1994; 266: 1865-1869.
    • (1994) Science , vol.266 , pp. 1865-1869
    • Chang, Y.1    Cesarman, E.2    Pessin, M.S.3    Lee, F.4    Culpepper, J.5    Knowles, D.M.6
  • 7
    • 0033572954 scopus 로고    scopus 로고
    • AIDS-related opportunistic illnesses occurring after initiation of potent antiretroviral therapy: The Swiss HIV Cohort Study
    • Ledergerber B, Egger M, Erard V, Weber R, Hirschel B, Furrer H et al. AIDS-related opportunistic illnesses occurring after initiation of potent antiretroviral therapy: the Swiss HIV Cohort Study. JAMA 1999; 282: 2220-2226.
    • (1999) JAMA , vol.282 , pp. 2220-2226
    • Ledergerber, B.1    Egger, M.2    Erard, V.3    Weber, R.4    Hirschel, B.5    Furrer, H.6
  • 8
    • 77951192990 scopus 로고    scopus 로고
    • KSHV and the pathogenesis of Kaposi sarcoma: Listening to human biology and medicine
    • Ganem D. KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine. J Clin Invest 2010; 120: 939-949.
    • (2010) J Clin Invest , vol.120 , pp. 939-949
    • Ganem, D.1
  • 9
    • 26244451394 scopus 로고    scopus 로고
    • Human herpesvirus 8-a novel human pathogen
    • Edelman DC. Human herpesvirus 8-a novel human pathogen. Virol J 2005; 2: 78.
    • (2005) Virol J , vol.2 , pp. 78
    • Edelman, D.C.1
  • 10
    • 0037772150 scopus 로고    scopus 로고
    • Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes
    • Montaner S, Sodhi A, Molinolo A, Bugge TH, Sawai ET, He Y et al. Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent genes. Cancer Cell 2003; 3: 23-36.
    • (2003) Cancer Cell , vol.3 , pp. 23-36
    • Montaner, S.1    Sodhi, A.2    Molinolo, A.3    Bugge, T.H.4    Sawai, E.T.5    He, Y.6
  • 11
    • 33847619373 scopus 로고    scopus 로고
    • In vivorestricted and reversible malignancy induced by human herpesvirus-8 KSHV: A cell and animal model of virally induced Kaposi's sarcoma
    • Mutlu AD, Cavallin LE, Vincent L, Chiozzini C, Eroles P, Duran EM et al. In vivorestricted and reversible malignancy induced by human herpesvirus-8 KSHV: a cell and animal model of virally induced Kaposi's sarcoma. Cancer Cell 2007; 11: 245-258.
    • (2007) Cancer Cell , vol.11 , pp. 245-258
    • Mutlu, A.D.1    Cavallin, L.E.2    Vincent, L.3    Chiozzini, C.4    Eroles, P.5    Duran, E.M.6
  • 12
    • 0032532063 scopus 로고    scopus 로고
    • Chemokines activate Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor in mammalian cells in culture
    • Gershengorn MC, Geras-Raaka E, Varma A, Clark-Lewis I. Chemokines activate Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor in mammalian cells in culture. J Clin Invest 1998; 102: 1469-1472.
    • (1998) J Clin Invest , vol.102 , pp. 1469-1472
    • Gershengorn, M.C.1    Geras-Raaka, E.2    Varma, A.3    Clark-Lewis, I.4
  • 13
    • 84872238380 scopus 로고    scopus 로고
    • Molecular mechanisms deployed by virally encoded G protein-coupled receptors in human diseases
    • Montaner S, Kufareva I, Abagyan R, Gutkind JS. Molecular mechanisms deployed by virally encoded G protein-coupled receptors in human diseases. Annu Rev Pharmacol Toxicol 2013; 53: 331-354.
    • (2013) Annu Rev Pharmacol Toxicol , vol.53 , pp. 331-354
    • Montaner, S.1    Kufareva, I.2    Abagyan, R.3    Gutkind, J.S.4
  • 14
    • 0037320031 scopus 로고    scopus 로고
    • Kaposi's sarcoma-like tumors in a human herpesvirus 8 ORF74 transgenic mouse
    • Guo HG, Sadowska M, Reid W, Tschachler E, Hayward G, Reitz M. Kaposi's sarcoma-like tumors in a human herpesvirus 8 ORF74 transgenic mouse. J Virol 2003; 77: 2631-2639.
    • (2003) J Virol , vol.77 , pp. 2631-2639
    • Guo, H.G.1    Sadowska, M.2    Reid, W.3    Tschachler, E.4    Hayward, G.5    Reitz, M.6
  • 15
    • 0034614888 scopus 로고    scopus 로고
    • Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma
    • Yang TY, Chen SC, Leach MW, Manfra D, Homey B, Wiekowski M et al. Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma. J Exp Med 2000; 191: 445-454.
    • (2000) J Exp Med , vol.191 , pp. 445-454
    • Yang, T.Y.1    Chen, S.C.2    Leach, M.W.3    Manfra, D.4    Homey, B.5    Wiekowski, M.6
  • 16
    • 84905401601 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of KSHV oncogenesis of Kaposi's sarcoma associated with HIV/AIDS
    • Cavallin LE, Goldschmidt-Clermont P, Mesri EA. Molecular and cellular mechanisms of KSHV oncogenesis of Kaposi's sarcoma associated with HIV/AIDS. PLoS Pathogen 2014; 10: e1004154.
    • (2014) PLoS Pathogen , vol.10 , pp. e1004154
    • Cavallin, L.E.1    Goldschmidt-Clermont, P.2    Mesri, E.A.3
  • 17
    • 34247191134 scopus 로고    scopus 로고
    • Hippo signaling in organ size control
    • Pan D. Hippo signaling in organ size control. Genes Dev 2007; 21: 886-897.
    • (2007) Genes Dev , vol.21 , pp. 886-897
    • Pan, D.1
  • 18
    • 77951837150 scopus 로고    scopus 로고
    • The Hippo-YAP pathway in organ size control and tumorigenesis: An updated version
    • Zhao B, Li L, Lei Q, Guan KL. The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version. Genes Dev 2010; 24: 862-874.
    • (2010) Genes Dev , vol.24 , pp. 862-874
    • Zhao, B.1    Li, L.2    Lei, Q.3    Guan, K.L.4
  • 20
    • 84874257648 scopus 로고    scopus 로고
    • The Hippo pathway: Regulators and regulations
    • Yu FX, Guan KL. The Hippo pathway: regulators and regulations. Genes Dev 2013; 27: 355-371.
    • (2013) Genes Dev , vol.27 , pp. 355-371
    • Yu, F.X.1    Guan, K.L.2
  • 21
    • 77957883342 scopus 로고    scopus 로고
    • The hippo signaling pathway in development and cancer
    • Pan D. The hippo signaling pathway in development and cancer. Dev Cell 2010; 19: 491-505.
    • (2010) Dev Cell , vol.19 , pp. 491-505
    • Pan, D.1
  • 22
    • 84891748709 scopus 로고    scopus 로고
    • The two faces of Hippo: Targeting the Hippo pathway for regenerative medicine and cancer treatment
    • Johnson R, Halder G. The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment. Nat Rev Drug Discov 2013; 13: 63-79.
    • (2013) Nat Rev Drug Discov , vol.13 , pp. 63-79
    • Johnson, R.1    Halder, G.2
  • 23
    • 47549095853 scopus 로고    scopus 로고
    • TEAD mediates YAP-dependent gene induction and growth control
    • Zhao B, Ye X, Yu J, Li L, Li W, Li S et al. TEAD mediates YAP-dependent gene induction and growth control. Genes Dev 2008; 22: 1962-1971.
    • (2008) Genes Dev , vol.22 , pp. 1962-1971
    • Zhao, B.1    Ye, X.2    Yu, J.3    Li, L.4    Li, W.5    Li, S.6
  • 24
    • 42049120338 scopus 로고    scopus 로고
    • The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control
    • Zhang L, Ren F, Zhang Q, Chen Y, Wang B, Jiang J. The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control. Dev Cell 2008; 14: 377-387.
    • (2008) Dev Cell , vol.14 , pp. 377-387
    • Zhang, L.1    Ren, F.2    Zhang, Q.3    Chen, Y.4    Wang, B.5    Jiang, J.6
  • 25
    • 40849086201 scopus 로고    scopus 로고
    • SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila
    • Goulev Y, Fauny JD, Gonzalez-Marti B, Flagiello D, Silber J, Zider A. SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila. Curr Biol 2008; 18: 435-441.
    • (2008) Curr Biol , vol.18 , pp. 435-441
    • Goulev, Y.1    Fauny, J.D.2    Gonzalez-Marti, B.3    Flagiello, D.4    Silber, J.5    Zider, A.6
  • 26
    • 0035873391 scopus 로고    scopus 로고
    • TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm
    • Vassilev A, Kaneko KJ, Shu H, Zhao Y, DePamphilis ML. TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm. Genes Dev 2001; 15: 1229-1241.
    • (2001) Genes Dev , vol.15 , pp. 1229-1241
    • Vassilev, A.1    Kaneko, K.J.2    Shu, H.3    Zhao, Y.4    DePamphilis, M.L.5
  • 27
    • 42049116586 scopus 로고    scopus 로고
    • The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway
    • Wu S, Liu Y, Zheng Y, Dong J, Pan D. The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway. Dev Cell 2008; 14: 388-398.
    • (2008) Dev Cell , vol.14 , pp. 388-398
    • Wu, S.1    Liu, Y.2    Zheng, Y.3    Dong, J.4    Pan, D.5
  • 28
    • 34548636132 scopus 로고    scopus 로고
    • Elucidation of a universal size-control mechanism in Drosophila and mammals
    • Dong J, Feldmann G, Huang J, Wu S, Zhang N, Comerford SA et al. Elucidation of a universal size-control mechanism in Drosophila and mammals. Cell 2007; 130: 1120-1133.
    • (2007) Cell , vol.130 , pp. 1120-1133
    • Dong, J.1    Feldmann, G.2    Huang, J.3    Wu, S.4    Zhang, N.5    Comerford, S.A.6
  • 30
    • 84857136357 scopus 로고    scopus 로고
    • YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy
    • von Gise A, Lin Z, Schlegelmilch K, Honor LB, Pan GM, Buck JN et al. YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy. Proc Natl Acad Sci USA 2012; 109: 2394-2399.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 2394-2399
    • Von Gise, A.1    Lin, Z.2    Schlegelmilch, K.3    Honor, L.B.4    Pan, G.M.5    Buck, J.N.6
  • 31
    • 0032907439 scopus 로고    scopus 로고
    • Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction
    • St JM, Tao W, Fei X, Fukumoto R, Carcangiu ML, Brownstein DG et al. Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction. Nat Genet 1999; 21: 182-186.
    • (1999) Nat Genet , vol.21 , pp. 182-186
    • St, J.M.1    Tao, W.2    Fei, X.3    Fukumoto, R.4    Carcangiu, M.L.5    Brownstein, D.G.6
  • 32
    • 42349088170 scopus 로고    scopus 로고
    • A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells
    • Chan SW, Lim CJ, Guo K, Ng CP, Lee I, Hunziker W et al. A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells. Cancer Res 2008; 68: 2592-2598.
    • (2008) Cancer Res , vol.68 , pp. 2592-2598
    • Chan, S.W.1    Lim, C.J.2    Guo, K.3    Ng, C.P.4    Lee, I.5    Hunziker, W.6
  • 34
    • 35948961118 scopus 로고    scopus 로고
    • Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
    • Zhao B, Wei X, Li W, Udan RS, Yang Q, Kim J et al. Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev 2007; 21: 2747-2761.
    • (2007) Genes Dev , vol.21 , pp. 2747-2761
    • Zhao, B.1    Wei, X.2    Li, W.3    Udan, R.S.4    Yang, Q.5    Kim, J.6
  • 35
    • 72549090299 scopus 로고    scopus 로고
    • YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation
    • Fernandez-L A, Northcott PA, Dalton J, Fraga C, Ellison D, Angers S et al. YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation. Genes Dev 2009; 23: 2729-2741.
    • (2009) Genes Dev , vol.23 , pp. 2729-2741
    • Fernandez-L, A.1    Northcott, P.A.2    Dalton, J.3    Fraga, C.4    Ellison, D.5    Angers, S.6
  • 36
    • 70349295967 scopus 로고    scopus 로고
    • Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma
    • Xu MZ, Yao TJ, Lee NP, Ng IO, Chan YT, Zender L et al. Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma. Cancer 2009; 115: 4576-4585.
    • (2009) Cancer , vol.115 , pp. 4576-4585
    • Xu, M.Z.1    Yao, T.J.2    Lee, N.P.3    Ng, I.O.4    Chan, Y.T.5    Zender, L.6
  • 37
    • 73549095761 scopus 로고    scopus 로고
    • A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)
    • Zhao B, Li L, Tumaneng K, Wang CY, Guan KL. A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Genes Dev 2010; 24: 72-85.
    • (2010) Genes Dev , vol.24 , pp. 72-85
    • Zhao, B.1    Li, L.2    Tumaneng, K.3    Wang, C.Y.4    Guan, K.L.5
  • 38
    • 41949138130 scopus 로고    scopus 로고
    • Tumor suppressor LATS1 is a negative regulator of oncogene YAP
    • Hao Y, Chun A, Cheung K, Rashidi B, Yang X. Tumor suppressor LATS1 is a negative regulator of oncogene YAP. J Biol Chem 2008; 283: 5496-5509.
    • (2008) J Biol Chem , vol.283 , pp. 5496-5509
    • Hao, Y.1    Chun, A.2    Cheung, K.3    Rashidi, B.4    Yang, X.5
  • 39
    • 78549275131 scopus 로고    scopus 로고
    • The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase
    • Liu CY, Zha ZY, Zhou X, Zhang H, Huang W, Zhao D et al. The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase. J Biol Chem 2010; 285: 37159-37169.
    • (2010) J Biol Chem , vol.285 , pp. 37159-37169
    • Liu, C.Y.1    Zha, Z.Y.2    Zhou, X.3    Zhang, H.4    Huang, W.5    Zhao, D.6
  • 40
    • 41149098966 scopus 로고    scopus 로고
    • TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway
    • Lei QY, Zhang H, Zhao B, Zha ZY, Bai F, Pei XH et al. TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway. Mol Cell Biol 2008; 28: 2426-2436.
    • (2008) Mol Cell Biol , vol.28 , pp. 2426-2436
    • Lei, Q.Y.1    Zhang, H.2    Zhao, B.3    Zha, Z.Y.4    Bai, F.5    Pei, X.H.6
  • 42
    • 3142604959 scopus 로고    scopus 로고
    • Use of the red fluorescent protein as a marker of Kaposi's sarcoma-associated herpesvirus lytic gene expression
    • Vieira J, O'Hearn PM. Use of the red fluorescent protein as a marker of Kaposi's sarcoma-associated herpesvirus lytic gene expression. Virology 2004; 325: 225-240.
    • (2004) Virology , vol.325 , pp. 225-240
    • Vieira, J.1    O'Hearn, P.M.2
  • 43
    • 84865260845 scopus 로고    scopus 로고
    • Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling
    • Yu FX, Zhao B, Panupinthu N, Jewell JL, Lian I, Wang LH et al. Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. Cell 2012; 150: 780-791.
    • (2012) Cell , vol.150 , pp. 780-791
    • Yu, F.X.1    Zhao, B.2    Panupinthu, N.3    Jewell, J.L.4    Lian, I.5    Wang, L.H.6
  • 44
    • 84867182034 scopus 로고    scopus 로고
    • Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs)
    • Mo JS, Yu FX, Gong R, Brown JH, Guan KL. Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs). Genes Dev 2012; 26: 2138-2143.
    • (2012) Genes Dev , vol.26 , pp. 2138-2143
    • Mo, J.S.1    Yu, F.X.2    Gong, R.3    Brown, J.H.4    Guan, K.L.5
  • 45
    • 84878868616 scopus 로고    scopus 로고
    • Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation
    • Yu FX, Zhang Y, Park HW, Jewell JL, Chen Q, Deng Y et al. Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation. Genes Dev 2013; 27: 1223-1232.
    • (2013) Genes Dev , vol.27 , pp. 1223-1232
    • Yu, F.X.1    Zhang, Y.2    Park, H.W.3    Jewell, J.L.4    Chen, Q.5    Deng, Y.6
  • 46
    • 0036227312 scopus 로고    scopus 로고
    • Monoclonal antibody D2-40, a new marker of lymphatic endothelium, reacts with Kaposi's sarcoma and a subset of angiosarcomas
    • Kahn HJ, Bailey D, Marks A. Monoclonal antibody D2-40, a new marker of lymphatic endothelium, reacts with Kaposi's sarcoma and a subset of angiosarcomas. Mod Pathol 2002; 15: 434-440.
    • (2002) Mod Pathol , vol.15 , pp. 434-440
    • Kahn, H.J.1    Bailey, D.2    Marks, A.3
  • 47
    • 34548719323 scopus 로고    scopus 로고
    • TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complex
    • Tian Y, Kolb R, Hong JH, Carroll J, Li D, You J et al. TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complex. Mol Cell Biol 2007; 27: 6383-6395.
    • (2007) Mol Cell Biol , vol.27 , pp. 6383-6395
    • Tian, Y.1    Kolb, R.2    Hong, J.H.3    Carroll, J.4    Li, D.5    You, J.6
  • 48
    • 53049095670 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus K7 induces viral G protein-coupled receptor degradation and reduces its tumorigenicity
    • Feng H, Dong X, Negaard A, Feng P. Kaposi's sarcoma-associated herpesvirus K7 induces viral G protein-coupled receptor degradation and reduces its tumorigenicity. PLoS Pathogen 2008; 4: e1000157.
    • (2008) PLoS Pathogen , vol.4 , pp. e1000157
    • Feng, H.1    Dong, X.2    Negaard, A.3    Feng, P.4
  • 49
    • 0036118279 scopus 로고    scopus 로고
    • Patterns of gene expression and a transactivation function exhibited by the vGCR (ORF74) chemokine receptor protein of Kaposi's sarcoma-associated herpesvirus
    • Chiou CJ, Poole LJ, Kim PS, Ciufo DM, Cannon JS, Ap RC et al. Patterns of gene expression and a transactivation function exhibited by the vGCR (ORF74) chemokine receptor protein of Kaposi's sarcoma-associated herpesvirus. J Virol 2002; 76: 3421-3439.
    • (2002) J Virol , vol.76 , pp. 3421-3439
    • Chiou, C.J.1    Poole, L.J.2    Kim, P.S.3    Ciufo, D.M.4    Cannon, J.S.5    Ap, R.C.6
  • 50
    • 84862605178 scopus 로고    scopus 로고
    • Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
    • Liu-Chittenden Y, Huang B, Shim JS, Chen Q, Lee SJ, Anders RA et al. Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. Genes Dev 2012; 26: 1300-1305.
    • (2012) Genes Dev , vol.26 , pp. 1300-1305
    • Liu-Chittenden, Y.1    Huang, B.2    Shim, J.S.3    Chen, Q.4    Lee, S.J.5    Anders, R.A.6
  • 52
    • 0029091450 scopus 로고
    • Close association of the alpha subunits of Gq and G11 G proteins with actin filaments in WRK1 cells: Relation to G protein-mediated phospholipase C activation
    • Ibarrondo J, Joubert D, Dufour MN, Cohen-Solal A, Homburger V, Jard S et al. Close association of the alpha subunits of Gq and G11 G proteins with actin filaments in WRK1 cells: relation to G protein-mediated phospholipase C activation. Proc Natl Acad Sci USA 1995; 92: 8413-8417.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8413-8417
    • Ibarrondo, J.1    Joubert, D.2    Dufour, M.N.3    Cohen-Solal, A.4    Homburger, V.5    Jard, S.6
  • 53
    • 14644426000 scopus 로고    scopus 로고
    • Receptors coupled to heterotrimeric G proteins of the G12 family
    • Riobo NA, Manning DR. Receptors coupled to heterotrimeric G proteins of the G12 family. Trends Pharmacol Sci 2005; 26: 146-154.
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 146-154
    • Riobo, N.A.1    Manning, D.R.2
  • 54
    • 84855326431 scopus 로고    scopus 로고
    • Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
    • Zhao B, Li L, Wang L, Wang CY, Yu J, Guan KL. Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis. Genes Dev 2012; 26: 54-68.
    • (2012) Genes Dev , vol.26 , pp. 54-68
    • Zhao, B.1    Li, L.2    Wang, L.3    Wang, C.Y.4    Yu, J.5    Guan, K.L.6
  • 56
    • 33744961436 scopus 로고    scopus 로고
    • Inhibition of heme oxygenase-1 interferes with the transforming activity of the Kaposi sarcoma herpesvirus-encoded G protein-coupled receptor
    • Marinissen MJ, Tanos T, Bolos M, de Sagarra MR, Coso OA, Cuadrado A. Inhibition of heme oxygenase-1 interferes with the transforming activity of the Kaposi sarcoma herpesvirus-encoded G protein-coupled receptor. J Biol Chem 2006; 281: 11332-11346.
    • (2006) J Biol Chem , vol.281 , pp. 11332-11346
    • Marinissen, M.J.1    Tanos, T.2    Bolos, M.3    De Sagarra, M.R.4    Coso, O.A.5    Cuadrado, A.6
  • 57
    • 84902515862 scopus 로고    scopus 로고
    • Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP
    • Yu FX, Luo J, Mo JS, Liu G, Kim YC, Meng Z et al. Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP. Cancer Cell 2014; 25: 822-830.
    • (2014) Cancer Cell , vol.25 , pp. 822-830
    • Yu, F.X.1    Luo, J.2    Mo, J.S.3    Liu, G.4    Kim, Y.C.5    Meng, Z.6
  • 58
    • 0033901248 scopus 로고    scopus 로고
    • Differential viral protein expression in Kaposi's sarcoma-associated herpesvirus-infected diseases: Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease
    • Parravicini C, Chandran B, Corbellino M, Berti E, Paulli M, Moore PS et al. Differential viral protein expression in Kaposi's sarcoma-associated herpesvirus-infected diseases: Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease. Am J Pathol 2000; 156: 743-749.
    • (2000) Am J Pathol , vol.156 , pp. 743-749
    • Parravicini, C.1    Chandran, B.2    Corbellino, M.3    Berti, E.4    Paulli, M.5    Moore, P.S.6
  • 59
    • 84908063237 scopus 로고    scopus 로고
    • Human herpesvirus-8: Kaposi sarcoma, multicentric Castleman disease, and primary effusion lymphoma
    • Kaplan LD. Human herpesvirus-8: Kaposi sarcoma, multicentric Castleman disease, and primary effusion lymphoma. Hematol Am Soc Hematol Educ Program 2013; 2013: 103-108.
    • (2013) Hematol Am Soc Hematol Educ Program , vol.2013 , pp. 103-108
    • Kaplan, L.D.1
  • 60
    • 10644256411 scopus 로고    scopus 로고
    • Epstein-Barr virus-encoded BILF1 is a constitutively active G protein-coupled receptor
    • Paulsen SJ, Rosenkilde MM, Eugen-Olsen J, Kledal TN. Epstein-Barr virus-encoded BILF1 is a constitutively active G protein-coupled receptor. J Virol 2005; 79: 536-546.
    • (2005) J Virol , vol.79 , pp. 536-546
    • Paulsen, S.J.1    Rosenkilde, M.M.2    Eugen-Olsen, J.3    Kledal, T.N.4
  • 62
    • 84902482143 scopus 로고    scopus 로고
    • Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a Trio-regulated Rho GTPase signaling circuitry
    • Feng X, Degese MS, Iglesias-Bartolome R, Vaque JP, Molinolo AA, Rodrigues M et al. Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a Trio-regulated Rho GTPase signaling circuitry. Cancer Cell 2014; 25: 831-845.
    • (2014) Cancer Cell , vol.25 , pp. 831-845
    • Feng, X.1    Degese, M.S.2    Iglesias-Bartolome, R.3    Vaque, J.P.4    Molinolo, A.A.5    Rodrigues, M.6
  • 63
    • 0037075888 scopus 로고    scopus 로고
    • The molecular pathology of Kaposi's sarcoma-associated herpesvirus
    • Jenner RG, Boshoff C. The molecular pathology of Kaposi's sarcoma-associated herpesvirus. Biochim Biophys Acta 2002; 1602: 1-22.
    • (2002) Biochim Biophys Acta , vol.1602 , pp. 1-22
    • Jenner, R.G.1    Boshoff, C.2
  • 64
  • 65
    • 41149167130 scopus 로고    scopus 로고
    • An NF-kappaB gene expression signature contributes to Kaposi's sarcoma virus vGPCR-induced direct and paracrine neoplasia
    • Martin D, Galisteo R, Ji Y, Montaner S, Gutkind JS. An NF-kappaB gene expression signature contributes to Kaposi's sarcoma virus vGPCR-induced direct and paracrine neoplasia. Oncogene 2008; 27: 1844-1852.
    • (2008) Oncogene , vol.27 , pp. 1844-1852
    • Martin, D.1    Galisteo, R.2    Ji, Y.3    Montaner, S.4    Gutkind, J.S.5
  • 66
    • 84862146104 scopus 로고    scopus 로고
    • Insulin/IGF signaling drives cell proliferation in part via Yorkie/YAP
    • Strassburger K, Tiebe M, Pinna F, Breuhahn K, Teleman AA. Insulin/IGF signaling drives cell proliferation in part via Yorkie/YAP. Dev Biol 2012; 367: 187-196.
    • (2012) Dev Biol , vol.367 , pp. 187-196
    • Strassburger, K.1    Tiebe, M.2    Pinna, F.3    Breuhahn, K.4    Teleman, A.A.5
  • 67
    • 84868033711 scopus 로고    scopus 로고
    • Activation of the unfolded protein response by 2-deoxy-D-glucose inhibits Kaposi's sarcoma-associated herpesvirus replication and gene expression
    • Leung HJ, Duran EM, Kurtoglu M, Andreansky S, Lampidis TJ, Mesri EA. Activation of the unfolded protein response by 2-deoxy-D-glucose inhibits Kaposi's sarcoma-associated herpesvirus replication and gene expression. Antimicrob Agents Chemother 2012; 56: 5794-5803.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 5794-5803
    • Leung, H.J.1    Duran, E.M.2    Kurtoglu, M.3    Andreansky, S.4    Lampidis, T.J.5    Mesri, E.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.