Prediction of embryotoxic potential using the ReProGlo stem cell-based Wnt reporter assay

Reproductive Toxicology

Volumn 55, Issue , 2015, Pages 30-49

  Uibel, Frederik ^a   Schwarz, Michael ^a  

^a Institute of Experimental and Clinical Pharmacology and Toxicology   (Germany)

Author keywords

Alternative model; Developmental toxicity; Embryonic stem cells; In vitro; ReProGlo; Teratogens; Wnt signaling

Indexed keywords

WNT PROTEIN; LUCIFERASE; TERATOGENIC AGENT;

ALKYLATION; ANIMAL CELL; ARTICLE; ASSAY; CELL VIABILITY; CHEMICAL STRUCTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; EMBRYOTOXICITY; METABOLIC CAPACITY; NONHUMAN; PREDICTION; REPROGLO ASSAY; SIGNAL TRANSDUCTION; ANIMAL; BIOASSAY; CELL CULTURE; CELL SURVIVAL; DRUG EFFECTS; GENETICS; METABOLISM; MOUSE; REPORTER GENE; WNT SIGNALING PATHWAY;

ANIMALS; BIOLOGICAL ASSAY; CELL SURVIVAL; CELLS, CULTURED; EMBRYONIC STEM CELLS; GENES, REPORTER; LUCIFERASES; MICE; TERATOGENS; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84939416316     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2014.09.009     Document Type: Article

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