The teratogenic effect of carbamazepine: A meta-analysis of 1255 exposures

Reproductive Toxicology

Volumn 16, Issue 1, 2002, Pages 9-17

  Matalon, S ^a,b   Schechtman, S ^c   Goldzweig, G ^d   Ornoy, A ^a  

^a HEBREW UNIVERSITY   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c MINISTRY OF HEALTH   (Israel)

^d HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Carbamazepine; Development; Embryo; Epilepsy; Teratogenicity

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; PHENOBARBITAL; VALPROIC ACID;

ADULT; ANTICONVULSANT THERAPY; ARTICLE; CLINICAL TRIAL; CONGENITAL HEART MALFORMATION; CONGENITAL MALFORMATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG COMBINATION; EMBRYO; EMBRYO DEVELOPMENT; EPILEPSY; FEMALE; FETOMATERNAL TRANSFUSION; GESTATIONAL AGE; HUMAN; MAJOR CLINICAL STUDY; META ANALYSIS; NEURAL TUBE DEFECT; NEWBORN; PREGNANCY; PREGNANCY COMPLICATION; PROSPECTIVE STUDY; RISK; SPONTANEOUS ABORTION; TERATOGENICITY; URINARY TRACT MALFORMATION;

ABNORMALITIES, DRUG-INDUCED; ANTICONVULSANTS; CARBAMAZEPINE; DRUG THERAPY, COMBINATION; EPILEPSY; FEMALE; GESTATIONAL AGE; HUMANS; INFANT, NEWBORN; MATERNAL-FETAL EXCHANGE; PREGNANCY; PREGNANCY COMPLICATIONS; PROSPECTIVE STUDIES; RISK;

EID: 0036010428     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0890-6238(01)00199-X     Document Type: Article

References (35)

1. Teratogenicity of antiepileptic drug combinations with special emphasis on epoxidation (of Carbamazepine)
2. Are anti epileptic drugs harmful when taken during pregnancy?
3. The teratogenic risk of anti epileptic drugs
4. Malformations in offspring of women with epilepsy: A prospective study
5. Carbamazepine clinical pharmacology: A review
6. Maternal use of anti epileptic drugs and the risk of major congenital malformations: A joint European prospective study of human teratogenesis associated with maternal epilepsy
7. Outcome of children born to epileptic mothers treated with Carbamazepine during pregnancy
8. Pattern of malformations in the children of women treated with carbamazapine during pregnancy
9. Spina bifida in infants of women treated with carbamazepine during pregnancy
10. Fetal head growth retardation associated with maternal antiepileptic drugs
11. Malformation in infants of mothers with epilepsy receiving antiepileptic drugs
12. Outcomes of pregnancy associated with antiepileptic drugs
13. Antiepileptic drugs and teratogenesis in two consecutive cohorts: Changes in prescription policy paralleled by changes in pattern of malformations
14. Antiepileptic medication in pregnancy: Late effects on the children central nervous system development
15. Neuro-development of children exposed in utero to phenytoin and carbamazepine monotherapy
16. Multi institutional study on the teratogenicity and fetal toxicity of antiepileptic drugs: A report of a collaborative study group in Japan
17. Teratogenicity of antiepileptic drugs: Analysis of possible risk factors
18. Carbamazepine use in pregnancy: The drug of choice? A prospective controlled follow up of 210 pregnancies after first trimester exposure
19. Antiepileptic drugs regiment and major congenital abnormalities in the offspring
20. Body dimensions of infants exposed to antiepileptic drugs in utero: Observations spanning 25 years
21. The teratogenicity of anticonvulsant drugs
22. Drugs in pregnancy: Anticonvulsants
23. The teratogenic risk of antiepileptic drugs
24. Aspetti epidemiologici delle malformazioni congenite
25. J Pharm. Teratogenicity of Carbamazepine in the SWV mouse
26. A: Pregnancy, and fetal complications in epileptic pregnancies: Review of the literature. B: Outcome of pregnancy in women with epilepsy, Norway 1967-1978
27. Folic acid antagonists during pregnancy and the risk of birth defects
28. Facial cleft in sibs and children of epileptic patients
29. Teratogenic effects of antiepileptic drugs: Implications for the management of epilepsy in women of childbearing age
30. Neural tube defects in relation to use of folic acid antagonists during pregnancy
31. Intelligence and physical features of children of women with epilepsy
32. Psychomotor development and minor anomalies in children exposed to antiepileptic drugs in utero: A prospective population based study
33. A clinical study of 57 children with fetal anticonvulsant syndromes