Mechanism of metabolic activation and DNA adduct formation by the human carcinogen diethylstilbestrol: The defining link to natural estrogens

International Journal of Cancer

Volumn 124, Issue 6, 2009, Pages 1276-1284

  Saeed, Muhammad ^a   Rogan, Eleanor ^a   Cavalieri, Ercole ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Depurinating DES DNA adducts; DES catechol quinone; Metabolic activation of DES

Indexed keywords

3' HYDROXYDIETHYLSTILBESTROL; CARCINOGEN; CATECHOL DERIVATIVE; DIENESTROL; DIETHYLSTILBESTROL; DIETHYLSTILBESTROL 3',4' QUINONE; DIETHYLSTILBESTROL DERIVATIVE; ESTROGEN; LACTOPEROXIDASE; MANGANESE OXIDE; MONOPHENOL MONOOXYGENASE; QUINONE DERIVATIVE; UNCLASSIFIED DRUG; CATECHOL; DNA;

ARTICLE; CARCINOGENESIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; COVALENT BOND; DNA ADDUCT; DNA BINDING; HYPOTHESIS; INTERCALATION COMPLEX; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLIC ACTIVATION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; REACTION ANALYSIS; SYNTHESIS; CHEMISTRY; FAST ATOM BOMBARDMENT MASS SPECTROMETRY; METABOLISM; OXIDATION REDUCTION REACTION;

CARCINOGENS; CATECHOLS; DIETHYLSTILBESTROL; DNA; DNA ADDUCTS; ESTROGENS; MODELS, MOLECULAR; OXIDATION-REDUCTION; QUINONES; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT;

EID: 60549105044     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24113     Document Type: Article

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