The role of Wnt in cell signaling and cell adhesion during early vertebrate development

Frontiers in Bioscience

Volumn 16, Issue 6, 2011, Pages 2352-2366

  Sylvie, Janssens ^a   Ellen, Crabbe ^a   Kris, Vleminckx ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Cell Adhesion; Gastrulation; Neurulation; Review; Somitogenesis; Wnt

Indexed keywords

VERTEBRATA;

CELL ADHESION MOLECULE; WNT PROTEIN;

ANIMAL; BIOLOGICAL MODEL; CELL ADHESION; CELL MOTION; EMBRYO DEVELOPMENT; EPITHELIAL MESENCHYMAL TRANSITION; GASTRULATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL CREST; NEURAL TUBE; PHYSIOLOGY; PRENATAL DEVELOPMENT; REVIEW; SIGNAL TRANSDUCTION; SOMITE;

ANIMALS; CELL ADHESION; CELL ADHESION MOLECULES; CELL MOVEMENT; EMBRYONIC DEVELOPMENT; EPITHELIAL-MESENCHYMAL TRANSITION; GASTRULATION; MODELS, BIOLOGICAL; NEURAL CREST; NEURAL TUBE; NEUROGENESIS; SIGNAL TRANSDUCTION; SOMITES; WNT PROTEINS;

EID: 79959685575     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/3858     Document Type: Article

References (111)

1. S. Sokol, J. L. Christian, R. T. Moon and D. A. Melton: Injected Wnt RNA induces a complete body axis in Xenopus embryos. Cell, 67(4), 741-52 (1991) (Pubitemid 121001487)
2. H. A. Kestler and M. Kuhl: From individual Wnt pathways towards a Wnt signalling network. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 363(1495), 1333-47 (2008) (Pubitemid 351311843)
3. M. V. Semenov, R. Habas, B. T. Macdonald and X. He: SnapShot: Noncanonical Wnt Signaling Pathways. Cell, 131(7), 1378 (2007)
4. J. Chien, W. H. Conrad and R. T. Moon: A Wnt survival guide: from flies to human disease. The Journal of investigative dermatology, 129(7), 1614-27 (2009)
5. J. Bilic, Y. L. Huang, G. Davidson, T. Zimmermann, C. M. Cruciat, M. Bienz and C. Niehrs: Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation. Science, 316(5831), 1619-22 (2007) (Pubitemid 46982035)
6. K. M. Cadigan and M. Peifer: Wnt signaling from development to disease: insights from model systems. Cold Spring Harbor perspectives in biology, 1(2), a002881 (2009)
7. D. Kohn and R. T. Moon: Wnt and calcium signaling: beta-catenin- independent pathways. Cell calcium, 38(3-4), 439-46 (2005) (Pubitemid 41283282)
8. E. K. Vladar, D. Antic and J. D. Axelrod: Planar cell polarity signaling: the developing cell's compass. Cold Spring Harbor perspectives in biology, 1(3), a002964 (2009)
9. M. T. Veeman, J. D. Axelrod and R. T. Moon: A second canon. Functions and mechanisms of beta-catenin independent Wnt signaling. Developmental cell, 5(3), 367-77 (2003) (Pubitemid 37107667)
10. H. Hikasa, M. Shibata, I. Hiratani and M. Taira: The Xenopus receptor tyrosine kinase Xror2 modulates morphogenetic movements of the axial mesoderm and neuroectoderm via Wnt signaling. Development, 129(22), 5227-39 (2002) (Pubitemid 35460686)
11. Oishi, H. Suzuki, N. Onishi, R. Takada, S. Kani, B. Ohkawara, I. Koshida, K. Suzuki, G. Yamada, G. C. Schwabe, S.Mundlos, H. Shibuya, S. Takada and Y. Minami: The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNKsignalling pathway. Genes to cells: devoted to molecular & cellular mechanisms, 8(7), 645-54 (2003) (Pubitemid 36880848)
12. Schambony and D. Wedlich: Wnt-5A/Ror2 regulate expression of XPAPC through an alternative noncanonical signaling pathway. Developmental Cell, 12(5), 779-92 (2007) (Pubitemid 46667742)
13. Joseph-Silverstein and R. L. Silverstein: Cell adhesion molecules: an overview. Cancer investigation, 16(3), 176-82 (1998) (Pubitemid 28158442)
14. R. L. Daugherty and C. J. Gottardi: Phospho-regulation of Beta-catenin adhesion and signaling functions. Physiology, 22,303-9 (2007)
15. I. Park, S. W. Kim, J. P. Lyons, H. Ji, T. T. Nguyen, K. Cho, M. C. Barton, T. Deroo, K. Vleminckx, R. T. Moon and P. D.McCrea: Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets. Developmental cell, 8(6), 843-54 (2005) (Pubitemid 40754056)
16. J. Zhurinsky, M. Shtutman and A. Ben-Ze'ev: Plakoglobin and beta-catenin: protein interactions, regulation and biological roles. Journal of cell science, 113 (Pt 18), 3127-39 (2000)
17. J. Heuberger and W. Birchmeier: Interplay of cadherinmediated cell adhesion and canonical Wnt signaling. Cold Spring Harbor perspectives in biology, 2(2), a002915 (2010)
18. W. J. Nelson and R. Nusse: Convergence of Wnt, betacatenin, and cadherin pathways. Science, 303(5663), 1483-7 (2004) (Pubitemid 38314410)
19. T. Yagi and M. Takeichi: Cadherin superfamily genes: functions, genomic organization, and neurologic diversity. Genes & development, 14(10), 1169-80 (2000) (Pubitemid 30327498)
20. Novak, S. C. Hsu, C. Leung-Hagesteijn, G. Radeva, J. Papkoff, R. Montesano, C. Roskelley, R. Grosschedl and S. Dedhar: Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways. Proceedings of the National Academy of Sciences of the United States of America, 95(8), 4374-9 (1998)
21. Tan, P. Costello, J. Sanghera, D. Dominguez, J. Baulida, A. G. de Herreros and S. Dedhar: Inhibition of integrin linked kinase (ILK) suppresses beta-catenin- Lef/Tcf-dependent transcription and expression of the Ecadherin repressor, snail, in APC-/- human colon carcinoma cells. Oncogene, 20(1), 133-40 (2001) (Pubitemid 32142346)
22. N. Gavert, M. Conacci-Sorrell, D. Gast, A. Schneider, P. Altevogt, T. Brabletz and A. Ben-Ze'ev: L1, a novel target of betacatenin signaling, transforms cells and is expressed at the invasive front of colon cancers. The Journal of cell biology, 168(4),633-42 (2005) (Pubitemid 40271028)
23. E. Conacci-Sorrell, T. Ben-Yedidia, M. Shtutman, E. Feinstein, P. Einat and A. Ben-Ze'ev: Nr-CAM is a target gene of the beta-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesis. Genes & development, 16(16), 2058-72 (2002)
24. Solnica-Krezel: Conserved patterns of cell movements during vertebrate gastrulation. Current biology : CB, 15(6), R21328 (2005)
25. Leptin: Gastrulation movements: the logic and the nuts and bolts. Developmental Cell, 8(3), 305-20 (2005) (Pubitemid 40309802)
26. M. Hammerschmidt and D. Wedlich: Regulated adhesion as a driving force of gastrulation movements. Development, 135(22), 3625-41 (2008)
27. S. C. Choi and S. Y. Sokol: The involvement of lethal giant larvae and Wnt signaling in bottle cell formation in Xenopus embryos. Dev Biol, 336(1), 68-75 (2009)
28. K. Hatta and M. Takeichi: Expression of N-cadherin adhesion molecules associated with early morphogenetic events in chick development. Nature, 320(6061), 447-9 (1986) (Pubitemid 16097807)
29. E. M. Fuchtbauer: Expression of M-twist during postimplantation development of the mouse. Developmental dynamics: an official publication of the American Association of Anatomists, 204(3), 316-22 (1995)
30. R. Jiang, Y. Lan, C. R. Norton, J. P. Sundberg and T. Gridley: The Slug gene is not essential for mesoderm or neural crest development in mice. Dev Biol, 198(2), 277-85 (1998) (Pubitemid 28304444)
31. E. A. Carver, R. Jiang, Y. Lan, K. F. Oram and T. Gridley: The mouse snail gene encodes a key regulator of the epithelialmesenchymal transition. Molecular and Cellular Biology, 21(23), 8184-8 (2001) (Pubitemid 33051806)
32. M. A. Nieto, M. G. Sargent, D. G. Wilkinson and J. Cooke: Control of cell behavior during vertebrate development by Slug, a zinc finger gene. Science, 264(5160), 835-9 (1994) (Pubitemid 24193449)
33. D. ten Berge, W. Koole, C. Fuerer, M. Fish, E. Eroglu and R. Nusse: Wnt signaling mediates self-organization and axis formation in embryoid bodies. Cell stem cell, 3(5), 508-18 (2008)
34. C. K. Speirs, K. K. Jernigan, S. H. Kim, Y. I. Cha, F. Lin, D. S. Sepich, R. N. DuBois, E. Lee and L. Solnica- Krezel:Prostaglandin Gbetagamma signaling stimulates gastrulation movements by limiting cell adhesion through Snai1a stabilization. Development, 137(8), 1327-37 (2010)
35. D. A. Kane, K. N. McFarland and R. M. Warga: Mutations in half baked/E-cadherin block cell behaviors that are necessary for teleost epiboly. Development, 132(5), 1105-16 (2005) (Pubitemid 40484943)
36. F. Carreira-Barbosa, M. Kajita, V. Morel, H. Wada, H. Okamoto, A. Martinez Arias, Y. Fujita, S. W. Wilson and M. Tada:Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation. Development, 136(3), 383-92 (2009)
37. R. Winklbauer, A. Selchow, M. Nagel and B. Angres: Cell interaction and its role in mesoderm cell migration during Xenopus gastrulation. Developmental Dynamics, 195(4), 290-302 (1992) (Pubitemid 23131716)
38. W. M. Brieher and B. M. Gumbiner: Regulation of Ccadherin function during activin induced morphogenesis of Xenopus animal caps. J Cell Biol, 126(2), 519-27 (1994) (Pubitemid 24226267)
39. C. H. Lee and B. M. Gumbiner: Disruption of gastrulation movements in Xenopus by a dominantnegative mutant for C-cadherin. Dev Biol, 171(2), 363-73 (1995)
40. Y. Zhong, W. M. Brieher and B. M. Gumbiner: Analysis of C-cadherin regulation during tissue morphogenesis with an activating antibody. J Cell Biol, 144(2), 351-9 (1999) (Pubitemid 29066037)
41. X. Chen and B. M. Gumbiner: Paraxial protocadherin mediates cell sorting and tissue morphogenesis by regulating Ccadherin adhesion activity. J Cell Biol, 174(2), 301-13 (2006) (Pubitemid 44079864)
42. S. Wacker, K. Grimm, T. Joos and R. Winklbauer: Development and control of tissue separation at gastrulation in Xenopus. Dev Biol, 224(2), 428-39 (2000) (Pubitemid 30661022)
43. Medina, R. K. Swain, K. M. Kuerner and H. Steinbeisser: Xenopus paraxial protocadherin has signaling functions and is involved in tissue separation. EMBO J, 23(16), 3249-58 (2004) (Pubitemid 39209149)
44. R. Winklbauer, A. Medina, R. K. Swain and H. Steinbeisser: Frizzled-7 signalling controls tissue separation during Xenopus gastrulation. Nature, 413(6858), 856-60 (2001) (Pubitemid 33026854)
45. M. J. Harrington, E. Hong, O. Fasanmi and R. Brewster: Cadherin-mediated adhesion regulates posterior body formation. BMC Dev Biol, 7, 130 (2007)
46. T. Usui, Y. Shima, Y. Shimada, S. Hirano, R. W. Burgess, T. L. Schwarz, M. Takeichi and T. Uemura: Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled. Cell, 98(5), 585-95 (1999) (Pubitemid 29418950)
47. S. Witzel, V. Zimyanin, F. Carreira-Barbosa, M. Tada and C. P. eisenberg: Wnt11 controls cell contact persistence by local accumulation of Frizzled 7 at the plasma membrane. J Cell Biol, 175(5), 791-802 (2006) (Pubitemid 44878511)
48. T. Goto and R. Keller: The planar cell polarity gene strabismus regulates convergence and extension and neural fold closure in Xenopus. Dev Biol, 247(1), 165-81 (2002) (Pubitemid 34681173)
49. M. Takeuchi, J. Nakabayashi, T. Sakaguchi, T. S. Yamamoto, H. Takahashi, H. Takeda and N. Ueno: The prickle-related gene in vertebrates is essential for gastrulation cell movements. Current biology : CB, 13(8), 674-9 (2003) (Pubitemid 36453317)
50. J. B. Wallingford and R. M. Harland: Xenopus Dishevelled signaling regulates both neural and mesodermal convergent extension: parallel forces elongating the body axis. Development, 128(13), 2581-92 (2001) (Pubitemid 32685099)
51. Kinoshita, H. Iioka, A. Miyakoshi and N. Ueno: PKC delta is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements. Genes Dev, 17(13), 1663-76 (2003) (Pubitemid 36828792)
52. E. Tahinci, C. A. Thorne, J. L. Franklin, A. Salic, K. M. Christian, L. A. Lee, R. J. Coffey and E. Lee: Lrp6 is required forconvergent extension during Xenopus gastrulation. Development, 134(22), 4095-106 (2007) (Pubitemid 350269426)
53. M. Kuhl, K. Geis, L. C. Sheldahl, T. Pukrop, R. T. Moon and D. Wedlich: Antagonistic regulation of convergent extension movements in Xenopus by Wnt/betacatenin and Wnt/Ca2+ signaling. Mech Dev, 106(1-2), 61-76 (2001) (Pubitemid 32701074)
54. S. Yamashita, C. Miyagi, A. Carmany-Rampey, T. Shimizu, R. Fujii, A. F. Schier and T. Hirano: Stat3 Controls Cell Movements during Zebrafish Gastrulation. Dev Cell, 2(3), 363-75 (2002) (Pubitemid 34266120)
55. J. A. Montero, L. Carvalho, M. Wilsch-Brauninger, B. Kilian, C. Mustafa and C. P. Heisenberg: Shield formation at the onsetof zebrafish gastrulation. Development, 132(6), 1187-98 (2005) (Pubitemid 40528780)
56. F. Ulrich, M. Krieg, E. M. Schotz, V. Link, I. Castanon, V. Schnabel, A. Taubenberger, D. Mueller, P. H. Puech and C. P. Heisenberg: Wnt11 functions in gastrulation by controlling cell cohesion through Rab5c and E-cadherin. Dev Cell, 9(4), 555-64 (2005) (Pubitemid 41430738)
57. H. Puech, A. Taubenberger, F. Ulrich, M. Krieg, D. J. Muller and C. P. Heisenberg: Measuring cell adhesion forces ofprimary gastrulating cells from zebrafish using atomic force microscopy. J Cell Sci, 118(Pt 18), 4199-206 (2005) (Pubitemid 41488957)
58. E. L. George, E. N. Georges-Labouesse, R. S. Patel- King, H. Rayburn and R. O. Hynes: Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. Development, 119(4), 1079-91 (1993) (Pubitemid 23358578)
59. Winklbauer and R. E. Keller: Fibronectin, mesoderm migration, and gastrulation in Xenopus. Dev Biol,177(2), 413-26 (1996) (Pubitemid 26275894)
60. T. Darribere and J. E. Schwarzbauer: Fibronectin matrix composition and organization can regulate cell migration during amphibian development. Mechanisms of development, 92(2), 239-50 (2000) (Pubitemid 30155918)
61. T. Rozario, B. Dzamba, G. F. Weber, L. A. Davidson and D. W. DeSimone: The physical state of fibronectin matrix differentially regulates morphogenetic movements in vivo. Dev Biol, 327(2), 386-98 (2009)
62. B. J. Dzamba, K. R. Jakab, M. Marsden, M. A. Schwartz and D. W. DeSimone: Cadherin adhesion, tissue tension, and noncanonical Wnt signaling regulate fibronectin matrix organization. Developmental cell, 16(3), 421-32 (2009)
63. D. Gradl, M. Kuhl and D. Wedlich: The Wnt/Wg signal transducer beta-catenin controls fibronectin expression. Molecular and cellular biology, 19(8), 5576-87 (1999) (Pubitemid 29339915)
64. B. Christ, R. Huang and M. Scaal: Amniote somite derivatives. Developmental dynamics: an official publication of the American Association of Anatomists, 236(9), 2382-96 (2007) (Pubitemid 47450929)
65. N. Holder and R. Klein: Eph receptors and ephrins: effectors of morphogenesis. Development, 126(10), 2033-44 (1999) (Pubitemid 29271689)
66. T. Watanabe, Y. Sato, D. Saito, R. Tadokoro and Y. Takahashi: EphrinB2 coordinates the formation of a morphologicalboundary and cell epithelialization during somite segmentation. Proceedings of the National Academy of Sciences of the United States of America, 106(18), 7467-72 (2009)
67. Y. Saga, N. Hata, H. Koseki and M. M. Taketo: Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. Genes & development, 11(14), 1827-39 (1997) (Pubitemid 27315212)
68. C. Rallis, S. M. Pinchin and D. Ish-Horowicz: Cellautonomous integrin control of Wnt and Notch signalling during somitogenesis. Development, 137(21), 3591-601 (2010)
69. D. Julich, R. Geisler and S. A. Holley: Integrinalpha5 and delta/notch signaling have complementary spatiotemporal requirements during zebrafish somitogenesis. Developmental cell, 8(4), 575-86 (2005) (Pubitemid 40450746)
70. J. T. Yang, B. L. Bader, J. A. Kreidberg, M. Ullman- Cullere, J. E. Trevithick and R. O. Hynes: Overlapping and independentfunctions of fibronectin receptor integrins in early mesodermal development. Dev Biol, 215(2), 264-77 (1999)
71. Koshida, Y. Kishimoto, H. Ustumi, T. Shimizu, M. Furutani-Seiki, H. Kondoh and S. Takada: Integrinalpha5- dependent fibronectin accumulation for maintenance of somite boundaries in zebrafish embryos. Developmenta cell, 8(4), 587-98 (2005) (Pubitemid 40450747)
72. W. C. Dunty, Jr., K. K. Biris, R. B. Chalamalasetty, M. M. Taketo, M. Lewandoski and T. P. Yamaguchi: Wnt3a/beta-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation. Development, 135(1), 8594 (2008)
73. G. L. Radice, H. Rayburn, H. Matsunami, K. A. Knudsen, M. Takeichi and R. O. Hynes: Developmental defects in mouse embryos lacking N-cadherin. Dev Biol, 181(1), 64-78 (1997) (Pubitemid 27079635)
74. K. Horikawa, G. Radice, M. Takeichi and O. Chisaka: Adhesive subdivisions intrinsic to the epithelial somites. Dev Biol, 215(2), 182-9 (1999)
75. J. L. Duband, S. Dufour, K. Hatta, M. Takeichi, G. M. Edelman and J. P. Thiery: Adhesion molecules during somitogenesisin the avian embryo. The Journal of cell biology, 104(5), 1361-74 (1987) (Pubitemid 17084495)
76. C. Schmidt, M. Stoeckelhuber, I. McKinnell, R. Putz, B. Christ and K. Patel: Wnt 6 regulates the epithelialisation process oft he segmental plate mesoderm leading to somite formation. Dev Biol, 271(1), 198-209 (2004) (Pubitemid 38757786)
77. C. Linker, C. Lesbros, J. Gros, L. W. Burrus, A. Rawls and C. Marcelle: beta-Catenin-dependent Wnt signalling controls the epithelial organisation of somites through the activation of paraxis. Development, 132(17), 3895-905 (2005) (Pubitemid 41410254)
78. Burgess, A. Rawls, D. Brown, A. Bradley and E. N. Olson: Requirement of the paraxis gene for somite formation and musculoskeletal patterning. Nature, 384(6609), 570-3 (1996) (Pubitemid 26415935)
79. J. K. Dale, P. Malapert, J. Chal, G. Vilhais-Neto, M. Maroto, T. Johnson, S. Jayasinghe, P. Trainor, B. Herrmann and O.Pourquie: Oscillations of the snail genes in the presomitic mesoderm coordinate segmental patterning and morphogenesis invertebrate somitogenesis. Developmental cell, 10(3), 355-66 (2006)
80. Y. Nakaya, S. Kuroda, Y. T. Katagiri, K. Kaibuchi and Y. Takahashi: Mesenchymal-epithelial transition during somatic segmentation is regulated by differential roles of Cdc42 and Rac1. Developmental cell, 7(3), 425-38 (2004) (Pubitemid 39232977)
81. Watanabe and Y. Takahashi: Tissue morphogenesis coupled with cell shape changes. Current opinion in genetics &development, 20(4), 443-7 (2010)
82. Y. Cinnamon, R. Ben-Yair and C. Kalcheim: Differential effects of N-cadherin-mediated adhesion on the development ofmyotomal waves. Development, 133(6), 1101-12 (2006)
83. J. Wagner, C. Schmidt, W. Nikowits, Jr. and B. Christ: Compartmentalization of the somite and myogenesis in chick embryos are influenced by wnt expression. Dev Biol, 228(1), 86-94 (2000)
84. P. Geetha-Loganathan, S. Nimmagadda, R. Huang, B. Christ and M. Scaal: Regulation of ectodermal Wnt6 expression by the neural tube is transduced by dermomyotomal Wnt11: a mechanism of dermomyotomal lip sustainment. Development, 133(15), 2897-904 (2006) (Pubitemid 44314267)
85. L. Ciani and P. C. Salinas: WNTs in the vertebrate nervous system: from patterning to neuronal connectivity. Nature reviews. Neuroscience, 6(5), 351-62 (2005) (Pubitemid 40593481)
86. G. C. Schoenwolf and J. L. Smith: Mechanisms of neurulation: traditional viewpoint and recent advances. Development,109(2), 243-70 (1990) (Pubitemid 20205566)
87. R. J. Detrick, D. Dickey and C. R. Kintner: The effects of N-cadherin misexpression on morphogenesis in Xenopus embryos.Neuron, 4(4), 493-506 (1990) (Pubitemid 20160839)
88. Fujimori, S. Miyatani and M. Takeichi: Ectopic expression of N-cadherin perturbs histogenesis in Xenopus embryos. Development, 110(1), 97-104 (1990)
89. Z. Lele, A. Folchert, M. Concha, G. J. Rauch, R. Geisler, F. Rosa, S. W. Wilson, M. Hammerschmidt and L. Bally-Cuif: parachute/n-cadherin is required for morphogenesis and maintained integrity of the zebrafish neural tube. Development, 129(14),3281-94 (2002)
90. S. I. Ganzler-Odenthal and C. Redies: Blocking Ncadherin function disrupts the epithelial structure of differentiating neural tissue in the embryonic chicken brain. The Journal of neuroscience: the official journal of the Society for Neuroscience, 18(14),5415-25 (1998) (Pubitemid 28311957)
91. Y. Luo, M. Ferreira-Cornwell, H. Baldwin, I. Kostetskii, J. Lenox, M. Lieberman and G. Radice: Rescuing the N-cadherin knockout by cardiac-specific expression of N-or E-cadherin. Development, 128(4), 459-69 (2001) (Pubitemid 32229589)
92. Hierholzer and R. Kemler: Beta-catenin-mediated signaling and cell adhesion in postgastrulation mouse embryos. Developmental dynamics: an official publication of the American Association of Anatomists, 239(1), 191-9 (2010)
93. H. Cremer, R. Lange, A. Christoph, M. Plomann, G. Vopper, J. Roes, R. Brown, S. Baldwin, P. Kraemer, S. Scheff and et al.: Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning. Nature, 367(6462), 455-9 (1994) (Pubitemid 24046046)
94. N. M. Abdul-Aziz, M. Turmaine, N. D. Greene and A. J. Copp: EphrinA-EphA receptor interactions in mouse spinal neurulation: implications for neural fold fusion. The International journal of developmental biology, 53(4), 559-68 (2009)
95. S. Nandadasa, Q. Tao, N. R. Menon, J. Heasman and C. Wylie: N-and E-cadherins in Xenopus are specifically required in the neural and non-neural ectoderm, respectively, for F-actin assembly and morphogenetic movements. Development, 136(8),1327-38 (2009)
96. N. Ueno and N. D. Greene: Planar cell polarity genes and neural tube closure. Birth defects research. Part C, Embryo today: reviews, 69(4), 318-24 (2003) (Pubitemid 38076455)
97. M. Shariatmadari, J. Peyronnet, P. Papachristou, Z. Horn, K. M. Sousa, E. Arenas and T. Ringstedt: Increased Wnt levels in the neural tube impair the function of adherens junctions during neurulation. Molecular and cellular neurosciences, 30(3), 437-51(2005) (Pubitemid 41416561)
98. M. Lindqvist, Z. Horn, V. Bryja, G. Schulte, P. Papachristou, R. Ajima, C. Dyberg, E. Arenas, T. P. Yamaguchi, H. Lagercrantz and T. Ringstedt: Vang-like protein 2 and Rac1 interact to regulate adherens junctions. Journal of cell science, 123(Pt 3), 472-83 (2010)
99. N. Kinoshita, N. Sasai, K. Misaki and S. Yonemura: Apical accumulation of Rho in the neural plate is important for neural plate cell shape change and neural tube formation. Molecular biology of the cell, 19(5), 2289-99 (2008)
100. M. K. Nyholm, S. Abdelilah-Seyfried and Y. Grinblat: A novel genetic mechanism regulates dorsolateral hinge-point formation during zebrafish cranial neurulation. Journal of cell science, 122(Pt 12), 2137-48 (2009)
101. L. A. Taneyhill: To adhere or not to adhere: the role of Cadherins in neural crest development. Cell adhesion & migration, 2(4), 223-30 (2008)
102. S. Nakagawa and M. Takeichi: Neural crest emigration from the neural tube depends on regulated cadherin expression. Development, 125(15), 2963-71 (1998) (Pubitemid 28410220)
103. F. Monier-Gavelle and J. L. Duband: Control of Ncadherin- mediated intercellular adhesion in migrating neural crest cells in vitro. Journal of cell science, 108 ( Pt 12), 3839-53 (1995) (Pubitemid 26003216)
104. X. Xu, W. E. Li, G. Y. Huang, R. Meyer, T. Chen, Y. Luo, M. P. Thomas, G. L. Radice and C. W. Lo: Modulation of mouse neural crest cell motility by Ncadherin and connexin 43 gap junctions. The Journal of cell biology, 154(1), 217-30 (2001)
105. B. Steventon, C. Carmona-Fontaine and R. Mayor: Genetic network during neural crest induction: from cell specification to cell survival. Seminars in cell & developmental biology, 16(6), 647-54 (2005) (Pubitemid 41509376)
106. T. Burstyn-Cohen, J. Stanleigh, D. Sela-Donenfeld and C. Kalcheim: Canonical Wnt activity regulates trunk neural crest delamination linking BMP/noggin signaling with G1/S transition. Development, 131(21), 5327-39 (2004). (Pubitemid 39562178)
107. Shoval, A. Ludwig and C. Kalcheim: Antagonistic roles of full-length N-cadherin and its soluble BMP cleavage product in neural crest delamination. Development, 134(3), 491-501 (2007) (Pubitemid 46332486)
108. N. Gavert, M. Sheffer, S. Raveh, S. Spaderna, M. Shtutman, T. Brabletz, F. Barany, P. Paty, D. Notterman, E. Domany and Ben-Ze'ev: Expression of L1-CAM and ADAM10 in human colon cancer cells induces metastasis. Cancer research, 67(16),7703-12 (2007) (Pubitemid 47281363)
109. R. B. Anderson, K. N. Turner, A. G. Nikonenko, J. Hemperly, M. Schachner and H. M. Young: The cell adhesion molecule l1 is required for chain migration of neural crest cells in the developing mouse gut. Gastroenterology, 130(4), 1221-32 (2006)
110. S. Piloto and T. F. Schilling: Ovo1 links Wnt signaling with N-cadherin localization during neural crest migration. Development, 137(12), 1981-90 (2010)
111. C. Carmona-Fontaine, H. Matthews and R. Mayor: Directional cell migration in vivo: Wnt at the crest. Cell adhesion & migration, 2(4), 240-2 (2008)