-
1
-
-
78049495115
-
Epigenetic mechanisms that regulate cell identity
-
Barrero MJ, Boué S, Izpisúa Belmonte JC. Epigenetic mechanisms that regulate cell identity. Cell Stem Cell. 2010; 7:565-70.
-
(2010)
Cell Stem Cell.
, vol.7
, pp. 565-570
-
-
Barrero, M.J.1
Izpisúa Belmonte, J.C.2
-
3
-
-
84861912630
-
Programming of DNA methylation patterns
-
Cedar H, Bergman Y. Programming of DNA methylation patterns. Annu Rev Biochem. 2012; 81:97-117.
-
(2012)
Annu Rev Biochem.
, vol.81
, pp. 97-117
-
-
Cedar, H.1
Bergman, Y.2
-
4
-
-
34247368534
-
Epigenetics in development
-
Kiefer JC. Epigenetics in development. Dev Dyn. 2007; 236:1144-56.
-
(2007)
Dev Dyn.
, vol.236
, pp. 1144-1156
-
-
Kiefer, J.C.1
-
5
-
-
73549085850
-
DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker
-
Tost J. DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker. Mol Biotechnol. 2010; 44:71-81.
-
(2010)
Mol Biotechnol.
, vol.44
, pp. 71-81
-
-
Tost, J.1
-
6
-
-
0343285948
-
DNA methylation and gene activity
-
Cedar H. DNA methylation and gene activity. Cell. 1988; 1964:93-124.
-
(1988)
Cell.
, vol.1964
, pp. 93-124
-
-
Cedar, H.1
-
7
-
-
0037372003
-
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
-
Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet. 2003; 33:245-54.
-
(2003)
Nat Genet.
, vol.33
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
8
-
-
0033569641
-
Epigenetics: regulation through repression
-
Wolffe AP, Matzke MA. Epigenetics: regulation through repression. Science. 1999; 286:481-6.
-
(1999)
Science
, vol.286
, pp. 481-486
-
-
Wolffe, A.P.1
Matzke, M.A.2
-
9
-
-
84860561774
-
Epigenetic reprogramming of cancer cells via targeted DNA methylation
-
Rivenbark AG, Stolzenburg S, Beltran AS, Yuan X, Rots MG, Strahl BD, et al. Epigenetic reprogramming of cancer cells via targeted DNA methylation. Epigenetics Official J DNA Methylation Soc.2012;7. http://www.ncbi.nlm.nih.gov/pubmed/22419067 .
-
(2012)
Epigenetics Official J DNA Methylation Soc
, pp. 7
-
-
Rivenbark, A.G.1
Stolzenburg, S.2
Beltran, A.S.3
Yuan, X.4
Rots, M.G.5
Strahl, B.D.6
-
10
-
-
16544395591
-
DNA methylation and cancer
-
Das PM, Singal R. DNA methylation and cancer. J Clin Oncol. 2004; 22:4632-42.
-
(2004)
J Clin Oncol.
, vol.22
, pp. 4632-4642
-
-
Das, P.M.1
Singal, R.2
-
11
-
-
80054994283
-
Identification of genetic elements that autonomously determine DNA methylation states
-
Lienert F, Wirbelauer C, Som I, Dean A, Mohn F, Schübeler D. Identification of genetic elements that autonomously determine DNA methylation states. Nat Genet. 2011; 43:1091-7.
-
(2011)
Nat Genet.
, vol.43
, pp. 1091-1097
-
-
Lienert, F.1
Wirbelauer, C.2
Som, I.3
Dean, A.4
Mohn, F.5
Schübeler, D.6
-
12
-
-
84863986133
-
Functions of DNA methylation: islands, start sites, gene bodies and beyond
-
Jones PA. Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat Rev Genet. 2011; 13:484-92.
-
(2011)
Nat Rev Genet
, vol.13
, pp. 484-492
-
-
Jones, P.A.1
-
13
-
-
77249170184
-
Establishing, maintaining and modifying DNA methylation patterns in plants and animals
-
Law JA, Jacobsen SE. Establishing, maintaining and modifying DNA methylation patterns in plants and animals. Nat Rev Genet. 2010; 11:204-20.
-
(2010)
Nat Rev Genet.
, vol.11
, pp. 204-220
-
-
Law, J.A.1
Jacobsen, S.E.2
-
14
-
-
35948981875
-
Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters
-
Shen L, Kondo Y, Guo Y, Zhang J, Zhang L, Ahmed S, et al. Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters. PLoS Genet. 2007; 3:2023-36.
-
(2007)
PLoS Genet.
, vol.3
, pp. 2023-2036
-
-
Shen, L.1
Kondo, Y.2
Guo, Y.3
Zhang, J.4
Zhang, L.5
Ahmed, S.6
-
16
-
-
0028104109
-
Sp1 elements protect a CpG island from de novo methylation
-
Brandeis M, Frank D, Keshet I, Siegfried Z, Mendelsohn M, Nemes A, et al. Sp1 elements protect a CpG island from de novo methylation. Nature. 1994; 371:435-8.
-
(1994)
Nature.
, vol.371
, pp. 435-438
-
-
Brandeis, M.1
Frank, D.2
Keshet, I.3
Siegfried, Z.4
Mendelsohn, M.5
Nemes, A.6
-
17
-
-
0027960055
-
Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island
-
Macleod D, Charlton J, Mullins J, Bird AP. Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island. Genes Dev. 1994; 8:2282-92.
-
(1994)
Genes Dev.
, vol.8
, pp. 2282-2292
-
-
Macleod, D.1
Charlton, J.2
Mullins, J.3
Bird, A.P.4
-
18
-
-
76749155779
-
VEZF1 elements mediate protection from DNA methylation
-
Dickson J, Gowher H, Strogantsev R, Gaszner M, Hair A, Felsenfeld G, et al. VEZF1 elements mediate protection from DNA methylation. PLoS Genet. 2010; 6:e1000804.
-
(2010)
PLoS Genet.
, vol.6
, pp. e1000804
-
-
Dickson, J.1
Gowher, H.2
Strogantsev, R.3
Gaszner, M.4
Hair, A.5
-
19
-
-
77949533111
-
An epigenetic signature in peripheral blood predicts active ovarian cancer
-
Teschendorff AE, Menon U, Gentry-Maharaj A, Ramus SJ, Gayther SA, Apostolidou S, et al. An epigenetic signature in peripheral blood predicts active ovarian cancer. PLoS One. 2009; 4:e8274.
-
(2009)
PLoS One.
, vol.4
, pp. e8274
-
-
Teschendorff, A.E.1
Menon, U.2
Gentry-Maharaj, A.3
Ramus, S.J.4
Gayther, S.A.5
Apostolidou, S.6
-
20
-
-
79956330964
-
CpG islands and the regulation of transcription
-
Deaton AM, Bird A. CpG islands and the regulation of transcription. Genes Dev. 2011; 25:1010-22.
-
(2011)
Genes Dev.
, vol.25
, pp. 1010-1022
-
-
Deaton, A.M.1
Bird, A.2
-
21
-
-
77957174102
-
Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated
-
Choy MK, Movassagh M, Goh HG, Bennett MR, Down T a, Foo RSY. Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated. BMC Genomics. 2010; 11:519.
-
(2010)
BMC Genomics.
, vol.11
, pp. 519
-
-
Choy, M.K.1
Movassagh, M.2
Goh, H.G.3
Bennett, M.R.4
Foo, R.S.Y.5
-
22
-
-
76749132083
-
General transcription factor binding at CpG islands in normal cells correlates with resistance to de novo DNA methylation in cancer cells
-
Gebhard C, Benner C, Ehrich M, Schwarzfischer L, Schilling E, Klug M, et al. General transcription factor binding at CpG islands in normal cells correlates with resistance to de novo DNA methylation in cancer cells. Cancer Res. 2010; 70:1398-407.
-
(2010)
Cancer Res.
, vol.70
, pp. 1398-1407
-
-
Gebhard, C.1
Benner, C.2
Ehrich, M.3
Schwarzfischer, L.4
Schilling, E.5
-
23
-
-
2542545717
-
Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells
-
Stirzaker C, Song JZ, Davidson B, Clark SJ. Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells. Cancer Res. 2004; 64(11):3871-7.
-
(2004)
Cancer Res.
, vol.64
, Issue.11
, pp. 3871-3877
-
-
Stirzaker, C.1
Song, J.Z.2
Davidson, B.3
Clark, S.J.4
-
25
-
-
34047116826
-
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
-
Weber M, Hellmann I, Stadler MB, Ramos L, Pääbo S, Rebhan M, et al. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet. 2007; 39:457-66.
-
(2007)
Nat Genet.
, vol.39
, pp. 457-466
-
-
Weber, M.1
Hellmann, I.2
Stadler, M.B.3
Ramos, L.4
Pääbo, S.5
Rebhan, M.6
-
26
-
-
49649125042
-
Genome-scale DNA methylation maps of pluripotent and differentiated cells
-
Meissner A, Mikkelsen TS, Gu H, Wernig M, Hanna J, Sivachenko A, et al. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature. 2008; 454:766-70.
-
(2008)
Nature.
, vol.454
, pp. 766-770
-
-
Meissner, A.1
Mikkelsen, T.S.2
Gu, H.3
Wernig, M.4
Hanna, J.5
Sivachenko, A.6
-
27
-
-
77953809032
-
Distinct epigenomic landscapes of pluripotent and lineage-committed human cells
-
Hawkins RD, Hon GC, Lee LK, Ngo Q, Lister R, Pelizzola M, et al. Distinct epigenomic landscapes of pluripotent and lineage-committed human cells. Cell Stem Cell. 2010; 6:479-91.
-
(2010)
Cell Stem Cell.
, vol.6
, pp. 479-491
-
-
Hawkins, R.D.1
Hon, G.C.2
Lee, L.K.3
Ngo, Q.4
Lister, R.5
Pelizzola, M.6
-
28
-
-
33746051706
-
Computational prediction of methylation status in human genomic sequences
-
Das R, Dimitrova N, Xuan Z, Rollins Ra, Haghighi F, Edwards JR, et al. Computational prediction of methylation status in human genomic sequences. Proc Natl Acad Sci U S A. 2006; 103:10713-16.
-
(2006)
Proc Natl Acad Sci U S A.
, vol.103
, pp. 10713-10716
-
-
Das, R.1
Dimitrova, N.2
Xuan, Z.3
Haghighi, F.4
Edwards, J.R.5
-
29
-
-
77249137168
-
Principles and challenges of genomewide DNA methylation analysis
-
Laird PW. Principles and challenges of genomewide DNA methylation analysis. Nat Rev Genet. 2010; 11:191-203.
-
(2010)
Nat Rev Genet.
, vol.11
, pp. 191-203
-
-
Laird, P.W.1
-
30
-
-
77649267695
-
Dynamic changes in the human methylome during differentiation
-
Laurent L, Wong E, Li G, Huynh T, Tsirigos A, Ong CT, et al. Dynamic changes in the human methylome during differentiation. Genome Res. 2010; 20:320-31.
-
(2010)
Genome Res.
, vol.20
, pp. 320-331
-
-
Laurent, L.1
Wong, E.2
Li, G.3
Huynh, T.4
Tsirigos, A.5
Ong, C.T.6
-
31
-
-
79952264847
-
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
-
Hon G, Antosiewicz-bourget J, Malley RO, Castanon R. Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature. 2011; 471(7336):68-73.
-
(2011)
Nature.
, vol.471
, Issue.7336
, pp. 68-73
-
-
Hon, G.1
Antosiewicz-bourget, J.2
Malley, R.O.3
Castanon, R.4
-
32
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister R, Pelizzola M, Dowen RH, Hawkins RD, Hon G, Tonti-Filippini J, et al. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature. 2009; 462:315-22.
-
(2009)
Nature.
, vol.462
, pp. 315-322
-
-
Lister, R.1
Pelizzola, M.2
Dowen, R.H.3
Hawkins, R.D.4
Hon, G.5
-
33
-
-
79958754527
-
Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome
-
Sandoval J, Heyn HA, Moran S, Serra-Musach J, Pujana MA, Bibikova M, et al. Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome. Epigenetics Official J DNA Methylation Soc. 2011; 6:692-702.
-
(2011)
Epigenetics Official J DNA Methylation Soc.
, vol.6
, pp. 692-702
-
-
Sandoval, J.1
Heyn, H.A.2
Moran, S.3
Serra-Musach, J.4
Pujana, M.A.5
Bibikova, M.6
-
34
-
-
80053304450
-
High density DNA methylation array with single CpG site resolution
-
Bibikova M, Barnes B, Tsan C, Ho V, Klotzle B, Le JM, et al. High density DNA methylation array with single CpG site resolution. Genomics. 2011; 98:288-95.
-
(2011)
Genomics.
, vol.98
, pp. 288-295
-
-
Bibikova, M.1
Barnes, B.2
Tsan, C.3
Ho, V.4
Klotzle, B.5
Le, J.M.6
-
35
-
-
79960688508
-
DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
-
Bell JT, Pai AA, Pickrell JK, Gaffney DJ, Pique-Regi R, Degner JF, et al. DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines. Genome Biol. 2011; 12:R10.
-
(2011)
Genome Biol.
, vol.12
, pp. R10
-
-
Bell, J.T.1
Pai, A.A.2
Pickrell, J.K.3
Gaffney, D.J.4
Pique-Regi, R.5
Degner, J.F.6
-
36
-
-
33751505540
-
DNA methylation profiling of human chromosomes 6, 20 and 22
-
Eckhardt F, Lewin J, Cortese R, Rakyan VK, Attwood J, Burger M, et al. DNA methylation profiling of human chromosomes 6, 20 and 22. Nat Genet. 2006; 38:1378-85.
-
(2006)
Nat Genet.
, vol.38
, pp. 1378-1385
-
-
Eckhardt, F.1
Lewin, J.2
Cortese, R.3
Rakyan, V.K.4
Attwood, J.5
Burger, M.6
-
37
-
-
84856555311
-
A DNA methylation fingerprint of 1628 human samples
-
Fernandez AF, Assenov Y, Martin-Subero JI, Balint B, Siebert R, Taniguchi H, et al. A DNA methylation fingerprint of 1628 human samples. Genome Res. 2011; 22:407-19.
-
(2011)
Genome Res.
, vol.22
, pp. 407-419
-
-
Fernandez, A.F.1
Assenov, Y.2
Martin-Subero, J.I.3
Balint, B.4
Siebert, R.5
Taniguchi, H.6
-
38
-
-
84898935560
-
Predicting DNA methylation level across human tissues
-
Ma B, Wilker EH, Willis-Owen SAG, Byun HM, Wong KCC, Motta V, et al. Predicting DNA methylation level across human tissues. Nucleic Acids Res. 2014; 42:3515-28.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. 3515-3528
-
-
Ma, B.1
Wilker, E.H.2
Willis-Owen, S.A.G.3
Byun, H.M.4
Wong, K.C.C.5
Motta, V.6
-
39
-
-
23644439586
-
Prediction of methylated CpGs in DNA sequences using a support vector machine
-
Bhasin M, Zhang H, Reinherz EL, Reche PA. Prediction of methylated CpGs in DNA sequences using a support vector machine. FEBS Lett. 2005; 579:4302-8.
-
(2005)
FEBS Lett.
, vol.579
, pp. 4302-4308
-
-
Bhasin, M.1
Zhang, H.2
Reinherz, E.L.3
Reche, P.A.4
-
40
-
-
33645777446
-
CpG island methylation in human lymphocytes is highly correlated with DNA sequence, repeats, and predicted DNA structure
-
Bock C, Paulsen M, Tierling S, Mikeska T, Lengauer T, Walter J. CpG island methylation in human lymphocytes is highly correlated with DNA sequence, repeats, and predicted DNA structure. PLoS Genet. 2006; 2:e26.
-
(2006)
PLoS Genet.
, vol.2
, pp. e26
-
-
Bock, C.1
Paulsen, M.2
Tierling, S.3
Mikeska, T.4
Lengauer, T.5
Walter, J.6
-
41
-
-
33748711235
-
Predicting methylation status of CpG islands in the human brain
-
Fang F, Fan S, Zhang X, Zhang MQ. Predicting methylation status of CpG islands in the human brain. Bioinformatics (Oxford, England). 2006; 22:2204-9.
-
(2006)
Bioinformatics (Oxford, England).
, vol.22
, pp. 2204-2209
-
-
Fang, F.1
Fan, S.2
Zhang, X.3
Zhang, M.Q.4
-
42
-
-
40549094047
-
Predicting DNA methylation susceptibility using CpG flanking sequences
-
Kim S, Li M, Paik H, Nephew K, Shi H, Kramer R, et al. Predicting DNA methylation susceptibility using CpG flanking sequences. Pac Symp Biocomput. 2008; 326:315-26.
-
(2008)
Pac Symp Biocomput.
, vol.326
, pp. 315-326
-
-
Kim, S.1
Li, M.2
Paik, H.3
Nephew, K.4
Shi, H.5
Kramer, R.6
-
43
-
-
48849095165
-
Histone methylation marks play important roles in predicting the methylation status of CpG islands
-
Fan S, Zhang MQ, Zhang X. Histone methylation marks play important roles in predicting the methylation status of CpG islands. Biochem Biophys Res Commun. 2008; 374:559-64.
-
(2008)
Biochem Biophys Res Commun.
, vol.374
, pp. 559-564
-
-
Fan, S.1
Zhang, M.Q.2
Zhang, X.3
-
44
-
-
84872895742
-
Predicting DNA methylation status using word composition
-
Lu L. Predicting DNA methylation status using word composition. J Biomed Sci Eng. 2010; 03:672-76.
-
(2010)
J Biomed Sci Eng.
, vol.3
, pp. 672-676
-
-
Lu, L.1
-
45
-
-
84872923864
-
CpGIMethPred: computational model for predicting methylation status of CpG islands in human genome
-
Zheng H, Wu H, Li J, Jiang SW. CpGIMethPred: computational model for predicting methylation status of CpG islands in human genome. BMC Med Genomics. 2013; 6:S13.
-
(2013)
BMC Med Genomics.
, vol.6
, pp. S13
-
-
Zheng, H.1
Wu, H.2
Li, J.3
Jiang, S.W.4
-
46
-
-
65849210556
-
Profile analysis and prediction of tissue-specific CpG island methylation classes
-
Previti C, Harari O, Zwir I, del Val C. Profile analysis and prediction of tissue-specific CpG island methylation classes. BMC Bioinformatics. 2009; 10:116.
-
(2009)
BMC Bioinformatics.
, vol.10
, pp. 116
-
-
Previti, C.1
Harari, O.2
Zwir, I.3
del Val, C.4
-
47
-
-
77954504873
-
Conserved role of intragenic DNA methylation in regulating alternative promoters
-
Maunakea AK, Nagarajan RP, Bilenky M, Ballinger TJ, D'Souza C, Fouse SD, et al. Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature. 2010; 466:253-7.
-
(2010)
Nature.
, vol.466
, pp. 253-257
-
-
Maunakea, A.K.1
Nagarajan, R.P.2
Bilenky, M.3
Ballinger, T.J.4
D'Souza, C.5
Fouse, S.D.6
-
48
-
-
84858159518
-
Prediction of methylation CpGs and their methylation degrees in human DNA sequences
-
Zhou X, Li Z, Dai Z, Zou X. Prediction of methylation CpGs and their methylation degrees in human DNA sequences. Comput Biol Med. 2012; 42(4):408-13.
-
(2012)
Comput Biol Med.
, vol.42
, Issue.4
, pp. 408-413
-
-
Zhou, X.1
Li, Z.2
Dai, Z.3
Zou, X.4
-
49
-
-
23744458086
-
Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes
-
Siepel A, Bejerano G, Pedersen JS, Hinrichs AS, Hou M, Rosenbloom K, et al. Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes. Genome Res. 2005; 15:1034-50.
-
(2005)
Genome Res.
, vol.15
, pp. 1034-1050
-
-
Siepel, A.1
Bejerano, G.2
Pedersen, J.S.3
Hinrichs, A.S.4
Hou, M.5
Rosenbloom, K.6
-
50
-
-
84872132897
-
DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker
-
Heyn H, Carmona FJ, Gomez A, Ferreira HJ, Bell JT, Sayols S, et al. DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker. Carcinogenesis. 2013; 34:102-8.
-
(2013)
Carcinogenesis.
, vol.34
, pp. 102-108
-
-
Heyn, H.1
Carmona, F.J.2
Gomez, A.3
Ferreira, H.J.4
Bell, J.T.5
Sayols, S.6
-
51
-
-
0036079158
-
The human genome browser at UCSC
-
Kent WJ, Sugnet CW, Furey TS, Roskin KM, Pringle TH, Zahler a M, et al. The human genome browser at UCSC. Genome Res. 2002; 12:996-1006.
-
(2002)
Genome Res.
, vol.12
, pp. 996-1006
-
-
Kent, W.J.1
Sugnet, C.W.2
Furey, T.S.3
Roskin, K.M.4
Pringle, T.H.5
Zahler a, M.6
-
52
-
-
84975742565
-
A map of human genome variation from population-scale sequencing
-
Durbin RM, Altshuler DL, Abecasis GR, Bentley DR, Chakravarti A, Clark AG, et al. A map of human genome variation from population-scale sequencing. Nature. 2010; 467:1061-73.
-
(2010)
Nature.
, vol.467
, pp. 1061-1073
-
-
Durbin, R.M.1
Altshuler, D.L.2
Abecasis, G.R.3
Bentley, D.R.4
Chakravarti, A.5
Clark, A.G.6
-
54
-
-
33745226498
-
Distant conserved sequences flanking endothelial-specific promoters contain tissue-specific DNase-hypersensitive sites and over-represented motifs
-
Bernat JA, Crawford GE, Ogurtsov AY, Collins FS, Ginsburg D, Kondrashov AS. Distant conserved sequences flanking endothelial-specific promoters contain tissue-specific DNase-hypersensitive sites and over-represented motifs. Hum Mol Genet. 2006; 15:2098-105.
-
(2006)
Hum Mol Genet.
, vol.15
, pp. 2098-2105
-
-
Bernat, J.A.1
Crawford, G.E.2
Ogurtsov, A.Y.3
Collins, F.S.4
Ginsburg, D.5
Kondrashov, A.S.6
-
55
-
-
79959524146
-
A haplotype map of the human genome
-
International HapMap Consortium. A haplotype map of the human genome. Nature. 2005; 437:1299-1320.
-
(2005)
Nature.
, vol.437
, pp. 1299-1320
-
-
-
56
-
-
7444260846
-
The ENCODE (ENCyclopedia Of DNA Elements) Project
-
Good PJ, Guyer MS, Kamholz S, Liefer L, Wetterstrand K, Kampa D, et al. The ENCODE (ENCyclopedia Of DNA Elements) Project. Science. 2004; 306:636-40.
-
(2004)
Science.
, vol.306
, pp. 636-640
-
-
Good, P.J.1
Guyer, M.S.2
Kamholz, S.3
Liefer, L.4
Wetterstrand, K.5
Kampa, D.6
-
58
-
-
78651237647
-
Identifying a high fraction of the human genome to be under selective constraint using GERP++
-
Davydov EV, Goode DL, Sirota M, Cooper GM, Sidow A, Batzoglou S. Identifying a high fraction of the human genome to be under selective constraint using GERP++. PLoS Comput Biol. 2010; 6:e1001025.
-
(2010)
PLoS Comput Biol.
, vol.6
, pp. e1001025
-
-
Davydov, E.V.1
Goode, D.L.2
Sirota, M.3
Cooper, G.M.4
Sidow, A.5
Batzoglou, S.6
-
59
-
-
84882884517
-
Charting a dynamic DNA methylation landscape of the human genome
-
Ziller MJ, Gu H, Müller F, Donaghey J, Tsai LTY, Kohlbacher O, et al. Charting a dynamic DNA methylation landscape of the human genome. Nature. 2013,:1-5. http://www.nature.com/doifinder/10.1038/nature12433 .
-
(2013)
Nature
, pp. 1-5
-
-
Ziller, M.J.1
Gu, H.2
Müller, F.3
Donaghey, J.4
Tsai, L.T.Y.5
Kohlbacher, O.6
-
60
-
-
80052918929
-
Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment
-
Hodges E, Molaro A, Dos Santos CO, Thekkat P, Song Q, Uren PJ, et al. Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment. Mol Cell. 2011; 44:17-28.
-
(2011)
Mol Cell.
, vol.44
, pp. 17-28
-
-
Hodges, E.1
Molaro, A.2
Dos Santos, C.O.3
Thekkat, P.4
Song, Q.5
Uren, P.J.6
-
62
-
-
59149084538
-
Genome-wide methylation analysis of human colon cancer reveals similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
-
Irizarry RA, Ladd-Acosta C, Wen B, Wu Z, Montano C, Onyango P, et al. Genome-wide methylation analysis of human colon cancer reveals similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet. 2009; 41:178-86.
-
(2009)
Nat Genet.
, vol.41
, pp. 178-186
-
-
Irizarry, R.A.1
Ladd-Acosta, C.2
Wen, B.3
Wu, Z.4
Montano, C.5
Onyango, P.6
-
63
-
-
70649095120
-
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts
-
Doi A, Park IH, Wen B, Murakami P, Aryee MJ, Irizarry R, et al. Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nat Genet. 2009; 41:1350-3.
-
(2009)
Nat Genet.
, vol.41
, pp. 1350-1353
-
-
Doi, A.1
Park, I.H.2
Wen, B.3
Murakami, P.4
Aryee, M.J.5
Irizarry, R.6
-
64
-
-
84875734577
-
Early de novo DNA methylation and prolonged demethylation in the muscle lineage
-
Tsumagari K, Baribault C, Terragni J, Varley KE, Gertz J, Pradhan S, et al. Early de novo DNA methylation and prolonged demethylation in the muscle lineage. Epigenetics: Official J DNA Methylation Soc. 2013; 8:317-32.
-
(2013)
Epigenetics: Official J DNA Methylation Soc.
, vol.8
, pp. 317-332
-
-
Tsumagari, K.1
Baribault, C.2
Terragni, J.3
Varley, K.E.4
Gertz, J.5
Pradhan, S.6
-
65
-
-
84864612696
-
Genome-wide DNA methylation profiles in hematopoietic stem and progenitor cells reveal overrepresentation of ETS transcription factor binding sites
-
Hogart A, Lichtenberg J, Ajay SS, Anderson S, Intramural NIH, Margulies EH, et al. Genome-wide DNA methylation profiles in hematopoietic stem and progenitor cells reveal overrepresentation of ETS transcription factor binding sites. Genome Res. 2012; 22:1407-18.
-
(2012)
Genome Res.
, vol.22
, pp. 1407-1418
-
-
Hogart, A.1
Lichtenberg, J.2
Ajay, S.S.3
Anderson, S.4
Intramural, N.I.H.5
Margulies, E.H.6
-
66
-
-
77952237515
-
RUNX3 is multifunctional in carcinogenesis of multiple solid tumors
-
Chuang LSH, Ito Y. RUNX3 is multifunctional in carcinogenesis of multiple solid tumors. Oncogene. 2010; 29:2605-15.
-
(2010)
Oncogene.
, vol.29
, pp. 2605-2615
-
-
Chuang, L.S.H.1
Ito, Y.2
-
67
-
-
18344389720
-
Causal relationship between the loss of RUNX3 expression and gastric cancer
-
Li QL, Ito K, Sakakura C, Fukamachi H, Inoue KI, Chi XZ, et al. Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell. 2002; 109:113-24.
-
(2002)
Cell.
, vol.109
, pp. 113-124
-
-
Li, Q.L.1
Ito, K.2
Sakakura, C.3
Fukamachi, H.4
Inoue, K.I.5
Chi, X.Z.6
-
68
-
-
27144524894
-
RUNX3 inactivation by point mutations and aberrant DNA methylation in bladder tumors
-
Kim WJ, Kim EJ, Jeong P, Quan C, Kim J, Li QL, et al. RUNX3 inactivation by point mutations and aberrant DNA methylation in bladder tumors. Cancer Res. 2005; 65:9347-54.
-
(2005)
Cancer Res.
, vol.65
, pp. 9347-9354
-
-
Kim, W.J.1
Kim, E.J.2
Jeong, P.3
Quan, C.4
Kim, J.5
Li, Q.L.6
-
69
-
-
33746121227
-
RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer
-
Lau QC, Raja E, Salto-Tellez M, Liu Q, Ito K, Inoue M, et al. RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer. Cancer Res. 2006; 66:6512-20.
-
(2006)
Cancer Res.
, vol.66
, pp. 6512-6520
-
-
Lau, Q.C.1
Raja, E.2
Salto-Tellez, M.3
Liu, Q.4
Ito, K.5
Inoue, M.6
-
70
-
-
33644876855
-
Epigenetic inactivation of the RUNX3 gene in lung cancer
-
Sato K, Tomizawa Y, Iijima H, Saito R, Ishizuka T, Nakajima T, et al. Epigenetic inactivation of the RUNX3 gene in lung cancer. Oncol Rep. 2006; 15:129-35.
-
(2006)
Oncol Rep.
, vol.15
, pp. 129-135
-
-
Sato, K.1
Tomizawa, Y.2
Iijima, H.3
Saito, R.4
Ishizuka, T.5
Nakajima, T.6
-
71
-
-
33745541234
-
CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
-
Weisenberger D, D Siegmund K, Campan M, Young J, Long T, Faasse M, et al. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet. 2006; 38:787-93.
-
(2006)
Nat Genet.
, vol.38
, pp. 787-793
-
-
Weisenberger, D.1
Siegmund, D.K.2
Campan, M.3
Young, J.4
Long, T.5
Faasse, M.6
-
72
-
-
33847672702
-
Loss of heterozygosity and microsatellite instability on chromosome arm 10q in neuroblastoma
-
Lázcoz P, Muñoz J, Nistal M, Pestaña A, Encío IJ, Castresana JS. Loss of heterozygosity and microsatellite instability on chromosome arm 10q in neuroblastoma. Cancer Genet Cytogenet. 2007; 174:1-8.
-
(2007)
Cancer Genet Cytogenet.
, vol.174
, pp. 1-8
-
-
Lázcoz, P.1
Muñoz, J.2
Nistal, M.3
Pestaña, A.4
Encío, I.J.5
Castresana, J.S.6
-
73
-
-
0035827545
-
Independent repression of a GC-rich housekeeping gene by Sp1 and MAZ involves the same cis-elements
-
Song J, Ugai H, Kanazawa I, Sun K, Yokoyama KK. Independent repression of a GC-rich housekeeping gene by Sp1 and MAZ involves the same cis-elements. J Biol Chem. 2001; 276:19897-904.
-
(2001)
J Biol Chem.
, vol.276
, pp. 19897-19904
-
-
Song, J.1
Ugai, H.2
Kanazawa, I.3
Sun, K.4
Yokoyama, K.K.5
-
74
-
-
0642316937
-
Transcriptional regulation by zinc-finger proteins Sp1 and MAZ involves interactions with the same cis-elements
-
Song J, Ugai H, Nakata-Tsutsui H, Kishikawa S, Suzuki E, Murata T, et al. Transcriptional regulation by zinc-finger proteins Sp1 and MAZ involves interactions with the same cis-elements. Int J Mol Med. 2003; 11:547-53.
-
(2003)
Int J Mol Med.
, vol.11
, pp. 547-553
-
-
Song, J.1
Ugai, H.2
Nakata-Tsutsui, H.3
Kishikawa, S.4
Suzuki, E.5
Murata, T.6
-
75
-
-
84908277219
-
Breaking the silence: the interplay between transcription factors and DNA methylation
-
Rejika, Croatia: InTech
-
Baron B. Breaking the silence: the interplay between transcription factors and DNA methylation. In: Methylation - from DNA, RNA and histones to diseases and treatment. Rejika, Croatia: InTech: 2012. p. 3-26.
-
(2012)
Methylation - from DNA, RNA and histones to diseases and treatment
, pp. 3-26
-
-
Baron, B.1
-
76
-
-
33745737494
-
Myc-binding-site recognition in the human genome is determined by chromatin context
-
Guccione E, Martinato F, Finocchiaro G, Luzi L, Tizzoni L, Dall' Olio V, et al. Myc-binding-site recognition in the human genome is determined by chromatin context. Nat Cell Biol. 2006; 8:764-70.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 764-770
-
-
Guccione, E.1
Martinato, F.2
Finocchiaro, G.3
Luzi, L.4
Tizzoni, L.5
-
77
-
-
77957369859
-
Epigenetic drivers of genetic alterations
-
Toyota M, Suzuki H. Epigenetic drivers of genetic alterations. Adv Genet. 2010; 70:309-23.
-
(2010)
Adv Genet.
, vol.70
, pp. 309-323
-
-
Toyota, M.1
Suzuki, H.2
-
78
-
-
19244370208
-
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis
-
Esteller M, Toyota M, Sanchez-Cespedes M, Capella G, Peinado MA, Watkins DN, et al. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis. Cancer Res. 2000; 60:2368-71.
-
(2000)
Cancer Res.
, vol.60
, pp. 2368-2371
-
-
Esteller, M.1
Toyota, M.2
Sanchez-Cespedes, M.3
Capella, G.4
Peinado, M.A.5
Watkins, D.N.6
-
79
-
-
84862832570
-
Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
-
Yang J, Ferreira T, Morris A P, Medland SE, Madden PAF, Heath AC, et al. Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits. Nat Genet. 2012; 44:369-75.
-
(2012)
Nat Genet.
, vol.44
, pp. 369-375
-
-
Yang, J.1
Ferreira, T.2
Medland, S.E.3
Madden, P.A.F.4
-
80
-
-
84885864334
-
A statin-dependent QTL for GATM expression is associated with statin-induced myopathy
-
Mangravite LM, Engelhardt BE, Medina MW, Smith JD, Brown CD, Chasman DI, et al. A statin-dependent QTL for GATM expression is associated with statin-induced myopathy. Nature. 2013; 502:377-80.
-
(2013)
Nature.
, vol.502
, pp. 377-380
-
-
Mangravite, L.M.1
Engelhardt, B.E.2
Medina, M.W.3
Smith, J.D.4
Brown, C.D.5
Chasman, D.I.6
-
81
-
-
84899630492
-
DNA methylome profiling of human tissues identifies global and tissue-specific methylation patterns
-
Lokk K, Modhukur V, Rajashekar B, Märtens K, Mägi R, Kolde R, et al. DNA methylome profiling of human tissues identifies global and tissue-specific methylation patterns. Genome Biol. 2014; 15:R54.
-
(2014)
Genome Biol.
, vol.15
, pp. R54
-
-
Lokk, K.1
Modhukur, V.2
Rajashekar, B.3
Märtens, K.4
Mägi, R.5
Kolde, R.6
-
82
-
-
84893192328
-
Accounting for cellular heterogeneity is critical in epigenome-wide association studies
-
Jaffe AE, Irizarry RA. Accounting for cellular heterogeneity is critical in epigenome-wide association studies. Genome Biol. 2014; 15:R31.
-
(2014)
Genome Biol.
, vol.15
, pp. R31
-
-
Jaffe, A.E.1
Irizarry, R.A.2
-
83
-
-
67651222400
-
A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
-
Howie BN, Donnelly P, Marchini J. A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet. 2009; 5:e1000529.
-
(2009)
PLoS Genet.
, vol.5
, pp. e1000529
-
-
Howie, B.N.1
Donnelly, P.2
Marchini, J.3
-
84
-
-
84864417548
-
Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
-
Howie B, Fuchsberger C, Stephens M, Marchini J, Abecasis GR. Fast and accurate genotype imputation in genome-wide association studies through pre-phasing. Nat Genet. 2012; 44:955-9.
-
(2012)
Nat Genet.
, vol.44
, pp. 955-959
-
-
Howie, B.1
Stephens, M.2
Marchini, J.3
Abecasis, G.R.4
-
85
-
-
79953673289
-
A genome-wide comparison of the functional properties of rare and common genetic variants in humans
-
Zhu Q, Ge D, Maia JM, Zhu M, Petrovski S, Dickson SP, et al. A genome-wide comparison of the functional properties of rare and common genetic variants in humans. Am J Hum Genet. 2011; 88:458-68.
-
(2011)
Am J Hum Genet.
, vol.88
, pp. 458-468
-
-
Zhu, Q.1
Ge, D.2
Maia, J.M.3
Zhu, M.4
Petrovski, S.5
Dickson, S.P.6
-
86
-
-
77951702343
-
Genetic heterogeneity in human disease
-
McClellan J, King MC. Genetic heterogeneity in human disease. Cell. 2010; 141:210-7.
-
(2010)
Cell
, vol.141
, pp. 210-217
-
-
McClellan, J.1
King, M.C.2
-
87
-
-
84895540377
-
Epigenome-wide association studies without the need for cell-type composition
-
Zou J, Lippert C, Heckerman D, Aryee M, Listgarten J. Epigenome-wide association studies without the need for cell-type composition. Nat Methods. 2014; 11:4-8.
-
(2014)
Nat Methods
, vol.11
, pp. 4-8
-
-
Zou, J.1
Lippert, C.2
Heckerman, D.3
Aryee, M.4
Listgarten, J.5
-
88
-
-
77953223693
-
Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain
-
Gibbs JR, Van Der Brug M P, Hernandez DG, Traynor BJ, Nalls MA, Lai SL, et al. Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain. PLoS Genet. 2010; 6:13.
-
(2010)
PLoS Genet.
, vol.6
, pp. 13
-
-
Gibbs, J.R.1
Van Der, B.2
Hernandez, D.G.3
Traynor, B.J.4
Nalls, M.A.5
Lai, S.L.6
-
89
-
-
77649204292
-
Genetic control of individual differences in gene-specific methylation in human brain
-
Zhang D, Cheng L, Badner JA, Chen C, Chen Q, Luo W, et al. Genetic control of individual differences in gene-specific methylation in human brain. Am J Hum Genet. 2010; 86:411-19.
-
(2010)
Am J Hum Genet.
, vol.86
, pp. 411-419
-
-
Zhang, D.1
Cheng, L.2
Badner, J.A.3
Chen, C.4
Chen, Q.5
Luo, W.6
-
90
-
-
84857111200
-
DNase I sensitivity QTLs are a major determinant of human expression variation
-
Degner JF, Pai Aa, Pique-Regi R, Veyrieras JB, Gaffney DJ, Pickrell JK, et al. DNase I sensitivity QTLs are a major determinant of human expression variation. Nature. 2012; 482:390-4.
-
(2012)
Nature.
, vol.482
, pp. 390-394
-
-
Degner, J.F.1
Pique-Regi, R.2
Veyrieras, J.B.3
Gaffney, D.J.4
Pickrell, J.K.5
-
91
-
-
84868154284
-
The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels
-
Pai AA, Cain CE, Mizrahi-Man O, De Leon S, Lewellen N, Veyrieras JB, et al. The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels. PLoS Genet. 2012; 8:e1003000.
-
(2012)
PLoS Genet.
, vol.8
, pp. e1003000
-
-
Pai, A.A.1
Cain, C.E.2
Mizrahi-Man, O.3
De Leon, S.4
Lewellen, N.5
-
92
-
-
84856321864
-
Dissecting the regulatory architecture of gene expression QTLs
-
Gaffney DJ, Veyrieras JB, Degner JF, Pique-Regi R, Pai AA, Crawford GE, et al. Dissecting the regulatory architecture of gene expression QTLs. Genome Biol. 2012; 13:R7.
-
(2012)
Genome Biol.
, vol.13
, pp. R7
-
-
Gaffney, D.J.1
Veyrieras, J.B.2
Degner, J.F.3
Pique-Regi, R.4
Pai, A.A.5
Crawford, G.E.6
-
94
-
-
84861333951
-
DNA methylation profiling identifies global methylation differences and markers of adrenocortical tumors
-
Rechache NS, Wang Y, Stevenson HS, Killian JK, Edelman DC, Merino M, et al. DNA methylation profiling identifies global methylation differences and markers of adrenocortical tumors. J Clin Endocrinol Metab. 2012; 97:E1004-13.
-
(2012)
J Clin Endocrinol Metab.
, vol.97
, pp. E1004-E1013
-
-
Rechache, N.S.1
Wang, Y.2
Stevenson, H.S.3
Killian, J.K.4
Edelman, D.C.5
Merino, M.6
-
95
-
-
84939174541
-
-
R project
-
R project. http://www.r-project.org/.
-
-
-
-
96
-
-
0025327524
-
Biplots in biomedical research
-
Gabriel KR, Odoroff CL. Biplots in biomedical research. Stat Med. 1990; 9:469-85.
-
(1990)
Stat Med.
, vol.9
, pp. 469-485
-
-
Gabriel, K.R.1
Odoroff, C.L.2
-
97
-
-
84939195844
-
-
Bioconductor open source software for bioinformatics
-
Bioconductor open source software for bioinformatics. http://www.bioconductor.org/ .
-
-
-
-
98
-
-
0345040873
-
Classification and regression by randomForest
-
Liaw A, Wiener M. Classification and regression by randomForest. R News. 2002; 2:18-22.
-
(2002)
R News
, vol.2
, pp. 18-22
-
-
Liaw, A.1
Wiener, M.2
-
99
-
-
84892410940
-
-
Meyer D, Dimitriadou E, Hornik K, Weingessel A, Leisch F. Misc functions of the Department of Statistics (e1071). 2012. http://cran.r-project.org/package=e1071 .
-
(2012)
Misc functions of the Department of Statistics
, pp. e1071
-
-
Meyer, D.1
Dimitriadou, E.2
Hornik, K.3
Weingessel, A.4
Leisch, F.5
-
100
-
-
84939137411
-
-
Golden Path track of the University of Santa Cruz Genome Browser
-
Golden Path track of the University of Santa Cruz Genome Browser. http://hgdownload.cse.ucsc.edu/goldenPath/hg19/gc5Base/.
-
-
-
-
101
-
-
84875404794
-
The UCSC genome browser database: extensions and updates 2013
-
Meyer LR, Zweig AS, Hinrichs AS, Karolchik D, Kuhn RM, Wong M, et al. The UCSC genome browser database: extensions and updates 2013. Nucleic Acids Res. 2013; 41:D64-9.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. D64-D69
-
-
Meyer, L.R.1
Zweig, A.S.2
Hinrichs, A.S.3
Karolchik, D.4
Kuhn, R.M.5
Wong, M.6
-
102
-
-
84939181164
-
-
Integrated Haplotype Scores from the University of Chicago
-
Integrated Haplotype Scores from the University of Chicago. http://hgdp.uchicago.edu/data/iHS/.
-
-
-
-
103
-
-
84939153446
-
-
Genomic Evolutionary Rate Profiling from the Sidow Lab at Stanford University
-
Genomic Evolutionary Rate Profiling from the Sidow Lab at Stanford University. http://mendel.stanford.edu/SidowLab/downloads/gerp/.
-
-
-
-
104
-
-
32244442679
-
Case studies in the use of ROC curve analysis for sensor-based estimates in human computer interaction
-
Inkpen K, Van De Panne M, editors. Canadian Human-Computer Communications Society, Canadian Human-Computer Communications Society
-
Fogarty J, Baker RS, Hudson SE. Case studies in the use of ROC curve analysis for sensor-based estimates in human computer interaction. In: Inkpen K, Van De Panne M, editors. GI 05 Proceedings of Graphics Interface 2005, ACM International Conference Proceeding Series. Canadian Human-Computer Communications Society, Canadian Human-Computer Communications Society: 2005. p. 129-36. http://www.cs.cmu.edu/afs/cs.cmu.edu/misc/mosaic/common/omega/Web/People/jfogarty/publications/gi2005.pdf .
-
(2005)
GI 05 Proceedings of Graphics Interface 2005, ACM International Conference Proceeding Series
, pp. 129-136
-
-
Fogarty, J.1
Baker, R.S.2
Hudson, S.E.3
-
105
-
-
27544491192
-
ROCR: visualizing classifier performance in R
-
Sing T, Sander O, Beerenwinkel N, Lengauer T. ROCR: visualizing classifier performance in R. Bioinformatics (Oxford, England). 2005; 21:3940-1.
-
(2005)
Bioinformatics (Oxford, England)
, vol.21
, pp. 3940-3941
-
-
Sing, T.1
Sander, O.2
Beerenwinkel, N.3
Lengauer, T.4
-
106
-
-
84939192252
-
-
Open-source software from the Engelhardt Group at Princeton University
-
Open-source software from the Engelhardt Group at Princeton University. http://www.cs.princeton.edu/~bee/software.html .
-
-
-
-
107
-
-
84857707318
-
ChromHMM: automating chromatin-state discovery and characterization
-
Ernst J, Kellis M. ChromHMM: automating chromatin-state discovery and characterization. Nat. Methods. 2012; 9:215-216.
-
(2012)
Nat. Methods.
, vol.9
, pp. 215-216
-
-
Ernst, J.1
Kellis, M.2
|