Neutrophils

Kelley's Textbook of Rheumatology: Volume 1-2, Ninth Edition

Volumn 1, Issue , 2012, Pages 152-169

  Scher, Jose U ^a,b,c   Abramson, Steven B ^a   Pillinger, Michael H ^a,d  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Microbiome Center for Rheumatology and Autoimmunity   (United States)

^c NYU HOSPITAL FOR JOINT DISEASES   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84938751642     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-1-4377-1738-9.00011-6     Document Type: Chapter

References (105)

1. BI Lord, MH Bronchud, S Owens, et al. (1989) The kinetics of human granulopoiesis following treatment with granulocyte colony-stimulating factor in vivo. Proc Natl Acad Sci U S A 86(23), 9499-9503
2. L Weiss (1970) Transmural cellular passage in vascular sinuses of rat bone marrow. Blood 36(2), 189-208
3. J Murray, JA Barbara, SA Dunkley, et al. (1997) Regulation of neutrophil apoptosis by tumor necrosis factor-alpha: requirement for TNFR55 and TNFR75 for induction of apoptosis in vitro. Blood 90(7), 2772-2783
4. C Tortorella, et al. (1998) Spontaneous and Fas-induced apoptotic cell death in aged neutrophils. J Clin Immunol 18(5), 321-329
5. C Martin, PC Burdon, G Bridger, et al. (2003) Chemokines acting via CXCR2 and CXCR4 control the release of neutrophils from the bone marrow and their return following senescence. Immunity 19(4), 583-593
6. N Borregaard, K Lollike, L Kjeldsen, et al. (1993) Human neutrophil granules and secretory vesicles. Eur J Haematol 51(4), 187-198
7. WM Nauseef, S McCormick and H Yi (1992) Roles of heme insertion and the mannose-6-phosphate receptor in processing of the human myeloid lysosomal enzyme, myeloperoxidase. Blood 80(10), 2622-2633
8. CA Owen and EJ Campbell (1999) The cell biology of leukocyte-mediated proteolysis. J Leukoc Biol 65(2), 137-150
9. B Dewald, U Bretz and M Baggiolini (1982) Release of gelatinase from a novel secretory compartment of human neutrophils. J Clin Invest 70(3), 518-525
10. N Borregaard, LJ Miller and TA Springer (1987) Chemoattractant-regulated mobilization of a novel intracellular compartment in human neutrophils. Science 237(4819), 1204-1206
11. A Belaaouaj, KS Kim and SD Shapiro (2000) Degradation of outer membrane protein A in Escherichia coli killing by neutrophil elastase. Science 289(5482), 1185-1188
12. C Coeshott, C Ohnemus, A Pilyavskaya, et al. (1999) Converting enzyme-independent release of tumor necrosis factor alpha and IL-1beta from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3. Proc Natl Acad Sci U S A 96(11), 6261-6266
13. U Schonbeck, F Mach and P Libby (1998) Generation of biologically active IL-1 beta by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1 beta processing. J Immunol 161(7), 3340-3346
14. PE Van den Steen, P Proost, A Wuyts, et al. (2000) Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-alpha and leaves RANTES and MCP-2 intact. Blood 96(8), 2673-2681
15. ML Huynh, VA Fadok and PM Henson (2002) Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation. J Clin Invest 109(1), 41-50
16. GM Bokoch (1995) Chemoattractant signaling and leukocyte activation. Blood 86(5), 1649-1660
17. MH Pillinger, AS Feoktistov, C Capodici, et al. (1996) Mitogen-activated protein kinase in neutrophils and enucleate neutrophil cytoplasts: evidence for regulation of cell-cell adhesion. J Biol Chem 271(20), 12049-12056
18. C Murdoch and A Finn (2000) Chemokine receptors and their role in inflammation and infectious diseases. Blood 95(10), 3032-3043
19. K Theilgaard-Monch, BT Porse and N Borregaard (2006) Systems biology of neutrophil differentiation and immune response. Curr Opin Immunol 18(1), 54-60
20. M Kawasaki, K Nakayama and S Wakatsuki (2005) Membrane recruitment of effector proteins by Arf and Rab GTPases. Curr Opin Struct Biol 15(6), 681-689
21. CP Morgan, H Sengelov, J Whatmore, et al. (1997) ADP-ribosylation-factor-regulated phospholipase D activity localizes to secretory vesicles and mobilizes to the plasma membrane following N-formylmethionyl-leucyl-phenylalanine stimulation of human neutrophils. Biochem J 325(Pt 3), 581-585
22. AR Amin, M Attur, P Vyas, et al. (1995) Expression of nitric oxide synthase in human peripheral blood mononuclear cells and neutrophils. J Inflamm 47(4), 190-205
23. JU Scher, MH Pillinger and SB Abramson (2007) Nitric oxide synthases and osteoarthritis. Curr Rheumatol Rep 9(1), 9-15
24. WM Nauseef, BD Volpp, S McCormick, et al. (1991) Assembly of the neutrophil respiratory burst oxidase. Protein kinase C promotes cytoskeletal and membrane association of cytosolic oxidase components. J Biol Chem 266(9), 5911-5917
25. C Capodici, MH Pillinger, G Han, et al. (1998) Integrin-dependent homotypic adhesion of neutrophils. Arachidonic acid activates Raf-1/Mek/Erk via a 5-lipoxygenase-dependent pathway. J Clin Invest 102(1), 165-175
26. C Capodici, S Hanft, M Feoktistov, et al. (1998) Phosphatidylinositol 3-kinase mediates chemoattractant-stimulated, CD11b/CD18-dependent cell-cell adhesion of human neutrophils: evidence for an ERK-independent pathway. J Immunol 160(4), 1901-1909
27. MR Philips, JP Buyon, R Winchester, et al. (1988) Up-regulation of the iC3b receptor (CR3) is neither necessary nor sufficient to promote neutrophil aggregation. J Clin Invest 82(2), 495-501
28. N Gautam, H Herwald and L Hedqvist Lindbom (2000) Signaling via beta(2) integrins triggers neutrophil-dependent alteration in endothelial barrier function. J Exp Med 191(11), 1829-1839
29. ZM Ding, JE Babensee, SI Simon, et al. (1999) Relative contribution of LFA-1 and Mac-1 to neutrophil adhesion and migration. J Immunol 163(9), 5029-5038
30. D Feng, JA Nagy, K Pyne, et al. (1998) Neutrophils emigrate from venules by a transendothelial cell pathway in response to FMLP. J Exp Med 187(6), 903-915
31. J Dangerfield, KY Larbi, MT Huang, et al. (2002) PECAM-1 (CD31) homophilic interaction up-regulates alpha6beta1 on transmigrated neutrophils in vivo and plays a functional role in the ability of alpha6 integrins to mediate leukocyte migration through the perivascular basement membrane. J Exp Med 196(9), 1201-1211
32. SJ Weiss (1989) Tissue destruction by neutrophils. N Engl J Med 320(6), 365-376
33. A Ozinsky, DM Underhill, JD Fontenot, et al. (2000) The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc Natl Acad Sci U S A 97(25), 13766-13771
34. F Hayashi, TK Means and AD Luster (2003) Toll-like receptors stimulate human neutrophil function. Blood 102(7), 2660-2669
35. E Caron and A Hall (1998) Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases. Science 282(5394), 1717-1721
36. FR DeLeo and MT Quinn (1996) Assembly of the phagocyte NADPH oxidase: molecular interaction of oxidase proteins. J Leukoc Biol 60(6), 677-691
37. RA Clark, BD Volpp, KG Leidal and WM Nauseef (1990) Two cytosolic components of the human neutrophil respiratory burst oxidase translocate to the plasma membrane during cell activation. J Clin Invest 85(3), 714-721
38. MR Philips, A Feoktistov, MH Pillinger and SB Abramson (1995) Translocation of p21rac2 from cytosol to plasma membrane is neither necessary nor sufficient for neutrophil NADPH oxidase activity. J Biol Chem 270(19), 11514-11521
39. JD Matute, AA Arias, MC Dinauer and PJ Patino (2005) p40phox: the last NADPH oxidase subunit. Blood Cells Mol Dis 35(2), 291-302
40. JD Matute, AA Arias, NA Wright, et al. (2009) A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40 phox and selective defects in neutrophil NADPH oxidase activity. Blood 114(15), 3309-3315
41. EP Reeves, H Lu, HL Jacobs, et al. (2002) Killing activity of neutrophils is mediated through activation of proteases by K+ flux. Nature 416(6878), 291-297
42. V Brinkmann, U Reichard, C Goosmann, et al. (2004) Neutrophil extracellular traps kill bacteria. Science 303(5663), 1532-1535
43. V Brinkmann and A Zychlinsky (2007) Beneficial suicide: why neutrophils die to make NETs. Nat Rev Microbiol 5(8), 577-582
44. S Massberg, L Grahl, ML von Bruehl, et al. (2010) Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases. Nat Med 16(8), 887-896
45. B Samuelsson, SE Dahlen, JA Lindgren, et al. (1987) Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. Science 237(4819), 1171-1176
46. SB Abramson, J Leszczynska-Piziak and G Weissmann (1991) Arachidonic acid as a second messenger. Interactions with a GTP-binding protein of human neutrophils. J Immunol 147(1), 231-236
47. N Chiang, M Arita and CN Serhan (2005) Anti-inflammatory circuitry: lipoxin, aspirin-triggered lipoxins and their receptor ALX. Prostaglandins Leukot Essent Fatty Acids 73(3-4), 163-177
48. CN Serhan (2005) Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution. Prostaglandins Leukot Essent Fatty Acids 73(3-4), 141-162
49. M Hamberg, J Svensson and B Samuelsson (1974) Prostaglandin endoperoxides. A new concept concerning the mode of action and release of prostaglandins. Proc Natl Acad Sci U S A 71(10), 3824-3828
50. MH Pillinger, MR Phillips, A Feoktistov and G Weismann (1995) Crosstalk in signal transduction via EP receptors: prostaglandin E1 inhibits chemoattractant-induced mitogen-activated protein kinase activity in human neutrophils. Adv Prostaglandin Thromboxane Leukot Res 23 311-316
51. P Scapini, JA Lapinet-Vera, S Gasperini, et al. (2000) The neutrophil as a cellular source of chemokines. Immunol Rev 177 195-203
52. K Theilgaard-Monch, LC Jacobsen, R Borup, et al. (2005) The transcriptional program of terminal granulocytic differentiation. Blood 105(4), 1785-1796
53. P Scapini, A Carletto, B Nardelli, et al. (2005) Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases. Blood 105(2), 830-837
54. MA Cassatella (2006) On the production of TNF-related apoptosis-inducing ligand (TRAIL/Apo-2L) by human neutrophils. J Leukoc Biol 79(6), 1140-1149
55. L Li, L Huang, AL Vergis, et al. (2010) IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemia-reperfusion injury. J Clin Invest 120(1), 331-342
56. DJ Cua and CM Tato (2010) Innate IL-17-producing cells: the sentinels of the immune system. Nat Rev Immunol 10(7), 479-489
57. J Reibman, S Meixler, TC Lee, et al. (1991) Transforming growth factor beta 1, a potent chemoattractant for human neutrophils, bypasses classic signal-transduction pathways. Proc Natl Acad Sci U S A 88(15), 6805-6809
58. SR McColl, R Paquin, C Menard and AD Beaulieu (1992) Human neutrophils produce high levels of the interleukin 1 receptor antagonist in response to granulocyte/macrophage colony-stimulating factor and tumor necrosis factor alpha. J Exp Med 176(2), 593-598
59. M Arita, F Bianchini, J Aliberti, et al. (2005) Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1. J Exp Med 201(5), 713-722
60. M Arita, T Ohira, YP Sun, et al. (2007) Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation. J Immunol 178(6), 3912-3917
61. CN Serhan, N Chiang and TE Van Dyke (2008) Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat Rev Immunol 8(5), 349-361
62. CN Serhan, R Yang, K Martinod, et al. (2009) Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions. J Exp Med 206(1), 15-23
63. A Papayianni, CN Serhan, ML Phillips, et al. (1995) Transcellular biosynthesis of lipoxin A4 during adhesion of platelets and neutrophils in experimental immune complex glomerulonephritis. Kidney Int 47(5), 1295-1302
64. JU Scher and MH Pillinger (2005) 15d-PGJ2: the anti-inflammatory prostaglandin? Clin Immunol 114(2), 100-109
65. M Perretti and F D’Acquisto (2009) Annexin A1 and glucocorticoids as effectors of the resolution of inflammation. Nat Rev Immunol 9(1), 62-70
66. JL Cash, R Hart, A Russ, et al. (2008) Synthetic chemerin-derived peptides suppress inflammation through ChemR23. J Exp Med 205(4), 767-775
67. CG Freire-de-Lima, YQ Xiao, SJ Gardai, et al. (2006) Apoptotic cells, through transforming growth factor-beta, coordinately induce anti-inflammatory and suppress pro-inflammatory eicosanoid and NO synthesis in murine macrophages. J Biol Chem 281(50), 38376-38384
68. GA McQuibban, JH Gong, EM Tam, et al. (2000) Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3. Science 289(5482), 1202-1206
69. I Bournazou, JD Pound, R Duffin, et al. (2009) Apoptotic human cells inhibit migration of granulocytes via release of lactoferrin. J Clin Invest 119(1), 20-32
70. MA Stark, Y Huo, TL Burcin, et al. (2005) Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. Immunity 22(3), 285-294
71. A Ariel, G Fredman, YP Sun, et al. (2006) Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression. Nat Immunol 7(11), 1209-1216
72. J Skokowa, M Germeshausen, C Zeidler and K Welte (2007) Severe congenital neutropenia: inheritance and pathophysiology. Curr Opin Hematol 14(1), 22-28
73. M Germeshausen, C Zeidler, N Stuhrmann, et al. (2010) Digenic mutations in severe congenital neutropenia. Haematologica 95(7), 1207-1210
74. PS Rosenberg, C Zeidler, AA Bolyard, et al. (2010) Stable long-term risk of leukaemia in patients with severe congenital neutropenia maintained on G-CSF therapy. Br J Haematol 150(2), 196-199
75. MS Horwitz, Z Duan, B Korkmaz, et al. (2007) Neutrophil elastase in cyclic and severe congenital neutropenia. Blood 109(5), 1817-1824
76. C Zeidler, M Germeshausen, C Klein and K Welte (2009) Clinical implications of ELA2-, HAX1-, and G-CSF-receptor (CSF3R) mutations in severe congenital neutropenia. Br J Haematol 144(4), 459-467
77. DC Anderson and TA Springer (1987) Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and p150,95 glycoproteins. Annu Rev Med 38 175-194
78. A Etzioni, M Frydman, S Pollack, et al. (1992) Brief report: recurrent severe infections caused by a novel leukocyte adhesion deficiency. N Engl J Med 327(25), 1789-1792
79. A McDowall, D Inwald, B Leitinger, et al. (2003) A novel form of integrin dysfunction involving beta1, beta2, and beta3 integrins. J Clin Invest 111(1), 51-60
80. MD Barbosa, QA Nguyen, VT Tcherneve, et al. (1996) Identification of the homologous beige and Chediak-Higashi syndrome genes. Nature 382(6588), 262-265
81. G Bohn, A Allroth, G Brandes, et al. (2007) A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14. Nat Med 13(1), 38-45
82. JM van den Berg, E van Koppen, A Ahlin, et al. (2009) Chronic granulomatous disease: the European experience. PLoS One 4(4), e5234
83. S Stein, MG Ott, S Schultz-Strasser, et al. (2010) Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease. Nat Med 16(2), 198-204
84. CL Ku, H von Bernuth, C Picard, et al. (2007) Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity. J Exp Med 204(10), 2407-2422
85. H von Bernuth, C Picard, Z Jin, et al. (2008) Pyogenic bacterial infections in humans with MyD88 deficiency. Science 321(5889), 691-696
86. JE Salmon, S Millard, LA Schacter, et al. (1996) Fc gamma RIIA alleles are heritable risk factors for lupus nephritis in African Americans. J Clin Invest 97(5), 1348-1354
87. AW Morgan, JH Barrett, B Griffiths, et al. (2006) Analysis of Fcgamma receptor haplotypes in rheumatoid arthritis: FCGR3A remains a major susceptibility gene at this locus, with an additional contribution from FCGR3B. Arthritis Res Ther 8(1), R5
88. NS Mandel (1976) The structural basis of crystal-induced membranolysis. Arthritis Rheum 19(Suppl 3), 439-445
89. A Cross, D Bakstad, JC Allen, et al. (2005) Neutrophil gene expression in rheumatoid arthritis. Pathophysiology 12(3), 191-202
90. G Weissmann, I Spilberg and K Krakauer (1969) Arthritis induced in rabbits by lysates of granulocyte lysosomes. Arthritis Rheum 12(2), 103-116
91. AD Befus, C Mowat, M Gilchrist, et al. (1999) Neutrophil defensins induce histamine secretion from mast cells: mechanisms of action. J Immunol 163(2), 947-953
92. K Raza, D Scheel-Toellner, CY Lee, et al. (2006) Synovial fluid leukocyte apoptosis is inhibited in patients with very early rheumatoid arthritis. Arthritis Res Ther 8(4), R120
93. SH Wong, N Francis, H Chahal, et al. (2009) Lactoferrin is a survival factor for neutrophils in rheumatoid synovial fluid. Rheumatology (Oxford) 48(1), 39-44
94. M Chen, BK Lam, Y Kanaoka, et al. (2006) Neutrophil-derived leukotriene B4 is required for inflammatory arthritis. J Exp Med 203(4), 837-842
95. N Tsuboi, T Ernandez, X Li, et al. (2011) Human neutrophil FcγRIIA regulation by C5aR promotes inflammatory arthritis in mice. Arthritis Rheum 63(2), 467-478
96. SB Abramson, J Dobro, MA Eberle, et al. (1991) Acute reversible hypoxemia in systemic lupus erythematosus. Ann Intern Med 114(11), 941-947
97. JJ Goronzy and CM Weyand (2002) Cytokines in giant-cell arteritis. Cleve Clin J Med 69(Suppl 2), SII91-94
98. HM Belmont, J Buyon, R Giorno and S Abramson (1994) Up-regulation of endothelial cell adhesion molecules characterizes disease activity in systemic lupus erythematosus. The Shwartzman phenomenon revisited. Arthritis Rheum 37(3), 376-383
99. MH Pillinger and SB Abramson (1995) The neutrophil in rheumatoid arthritis. Rheum Dis Clin North Am 21(3), 691-714
100. BN Cronstein, M Van de Stouwe, L Druska, et al. (1994) Nonsteroidal antiinflammatory agents inhibit stimulated neutrophil adhesion to endothelium: adenosine dependent and independent mechanisms. Inflammation 18(3), 323-335
101. MH Pillinger, C Capodici, P Rosenthal, et al. (1998) Modes of action of aspirin-like drugs: salicylates inhibit erk activation and integrin-dependent neutrophil adhesion. Proc Natl Acad Sci U S A 95(24), 14540-14545
102. BN Cronstein, MA Eberle, HE Gruber, et al. (1991) Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells. Proc Natl Acad Sci U S A 88(6), 2441-2445
103. BN Cronstein, Y Molad, J Reibman, et al. (1995) Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils. J Clin Invest 96(2), 994-1002
104. LW Moreland, RP Bucy, ME Weinblatt, et al. (2002) Immune function in patients with rheumatoid arthritis treated with etanercept. Clin Immunol 103(1), 13-21
105. F Capsoni, P Sarzi-Puttini, F Atzeni, et al. (2005) Effect of adalimumab on neutrophil function in patients with rheumatoid arthritis. Arthritis Res Ther 7(2), R250-255