Killing activity of neutrophils is mediated through activation of proteases by K+ flux

Nature

Volumn 416, Issue 6878, 2002, Pages 291-297

  Reeves, Emer P ^a   Lu, Hui ^a   Jacobs, Hugues Lortat ^b   Messina, Carlo G M ^a   Bolsover, Steve ^a   Gabellall, Giorgio ^a   Potma, Eric O ^c   Warley, Alice ^d   Roes, Jürgen ^a   Segal, Anthony W ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

^d ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIODIVERSITY; CATALYSIS; ENZYMES; MICROORGANISMS; POTASSIUM;

IODINATING CAPACITY;

TOXICITY;

CATHEPSIN G; CELL PROTEIN; ELASTASE; PROTEINASE; REACTIVE OXYGEN METABOLITE;

BACTERIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIMICROBIAL ACTIVITY; ARTICLE; BIOACCUMULATION; CANDIDIASIS; CELL ACTIVITY; CELL GRANULE; CONTROLLED STUDY; ENDOSOME; ENZYME ACTIVATION; ENZYME ACTIVITY; HALOGENATION; HUMAN; HUMAN CELL; INTRACELLULAR KILLING; IONIC STRENGTH; MOUSE; NEUTROPHIL; NONHUMAN; PH; PHAGOCYTOSIS; POTASSIUM CURRENT; POTASSIUM TRANSPORT; PRIORITY JOURNAL; STAPHYLOCOCCUS INFECTION;

ANIMALS; CANDIDIASIS; CYTOTOXICITY, IMMUNOLOGIC; ELECTROPHYSIOLOGY; ENZYME ACTIVATION; HUMANS; MICE; NEUTROPHILS; OXYGEN; PEROXIDASE; PHAGOSOMES; POTASSIUM; STAPHYLOCOCCAL INFECTIONS; SUPEROXIDES;

ANIMALIA; BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS;

EID: 0037149510     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/416291a     Document Type: Article

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