메뉴 건너뛰기




Volumn 16, Issue 8, 2015, Pages 910-922

G4-associated human diseases

Author keywords

ALS; FTD; G4; helicase; quadruplex

Indexed keywords

BLOOM SYNDROME HELICASE; DOUBLE STRANDED DNA; GUANINE QUADRUPLEX; HELICASE; REV PROTEIN; WERNER SYNDROME PROTEIN; XERODERMA PIGMENTOSUM GROUP D PROTEIN; DNA;

EID: 84938751599     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201540607     Document Type: Review
Times cited : (250)

References (98)
  • 1
    • 0023788886 scopus 로고
    • Formation of parallel four-stranded complexes by guanine rich motifs in DNA and its implications for meiosis
    • Sen D, Gilbert W, (1988) Formation of parallel four-stranded complexes by guanine rich motifs in DNA and its implications for meiosis. Nature 334: 364-366
    • (1988) Nature , vol.334 , pp. 364-366
    • Sen, D.1    Gilbert, W.2
  • 2
    • 0026430355 scopus 로고
    • Tetramerization of an RNA oligonucleotide containing a GGGG sequence
    • Kim J, Cheong C, Moore PB, (1991) Tetramerization of an RNA oligonucleotide containing a GGGG sequence. Nature 351: 331-332
    • (1991) Nature , vol.351 , pp. 331-332
    • Kim, J.1    Cheong, C.2    Moore, P.B.3
  • 5
    • 38049030699 scopus 로고    scopus 로고
    • Human telomere, oncogenic promoter and 5′-UTR G-quadruplexes: Diverse higher order DNA and RNA targets for cancer therapeutics
    • Patel DJ, Phan AT, Kuryavyi V, (2007) Human telomere, oncogenic promoter and 5′-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics. Nucleic Acids Res 35: 7429-7455
    • (2007) Nucleic Acids Res , vol.35 , pp. 7429-7455
    • Patel, D.J.1    Phan, A.T.2    Kuryavyi, V.3
  • 6
    • 79953313413 scopus 로고    scopus 로고
    • Targeting G-quadruplexes in gene promoters: A novel anticancer strategy?
    • Balasubramanian S, Hurley LH, Neidle S, (2011) Targeting G-quadruplexes in gene promoters: a novel anticancer strategy? Nat Rev Drug Discov 10: 261-275
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 261-275
    • Balasubramanian, S.1    Hurley, L.H.2    Neidle, S.3
  • 9
    • 84925599752 scopus 로고    scopus 로고
    • Looking for efficient G-quadruplex ligands: Evidence for selective stabilizing properties and telomere damage by drug-like molecules
    • Pagano B, Amato J, Iaccarino N, Cingolani C, Zizza P, Biroccio A, Novellino E, Randazzo A, (2015) Looking for efficient G-quadruplex ligands: evidence for selective stabilizing properties and telomere damage by drug-like molecules. ChemMedChem 10: 640-649
    • (2015) ChemMedChem , vol.10 , pp. 640-649
    • Pagano, B.1    Amato, J.2    Iaccarino, N.3    Cingolani, C.4    Zizza, P.5    Biroccio, A.6    Novellino, E.7    Randazzo, A.8
  • 10
    • 76349097100 scopus 로고    scopus 로고
    • Human telomeric G-quadruplex: Structures of DNA and RNA sequences
    • Phan AT, (2010) Human telomeric G-quadruplex: structures of DNA and RNA sequences. FEBS J 277: 1107-1117
    • (2010) FEBS J , vol.277 , pp. 1107-1117
    • Phan, A.T.1
  • 11
    • 84890418685 scopus 로고    scopus 로고
    • Structure of the human telomere in Na+ solution: An antiparallel (2+2) G-quadruplex scaffold reveals additional diversity
    • Lim KW, Ng VC, Martin-Pintado N, Heddi B, Phan AT, (2013) Structure of the human telomere in Na+ solution: an antiparallel (2+2) G-quadruplex scaffold reveals additional diversity. Nucleic Acids Res 41: 10556-10562
    • (2013) Nucleic Acids Res , vol.41 , pp. 10556-10562
    • Lim, K.W.1    Ng, V.C.2    Martin-Pintado, N.3    Heddi, B.4    Phan, A.T.5
  • 12
    • 79960516726 scopus 로고    scopus 로고
    • Structure of long human telomeric RNA (TERRA): G-quadruplexes formed by four and eight UUAGGG repeats are stable building blocks
    • Martadinata H, Heddi B, Lim KW, Phan AT, (2011) Structure of long human telomeric RNA (TERRA): G-quadruplexes formed by four and eight UUAGGG repeats are stable building blocks. Biochemistry 50: 6455-6461
    • (2011) Biochemistry , vol.50 , pp. 6455-6461
    • Martadinata, H.1    Heddi, B.2    Lim, K.W.3    Phan, A.T.4
  • 14
    • 0033034413 scopus 로고    scopus 로고
    • High affinity interactions of nucleolin with G-G-paired rDNA
    • Hanakahi LA, Sun H, Maizels N, (1999) High affinity interactions of nucleolin with G-G-paired rDNA. J Biol Chem 274: 15908-15912
    • (1999) J Biol Chem , vol.274 , pp. 15908-15912
    • Hanakahi, L.A.1    Sun, H.2    Maizels, N.3
  • 15
    • 78049439594 scopus 로고    scopus 로고
    • Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU
    • Lattmann S, Giri B, Vaughn JP, Akman SA, Nagamine Y, (2010) Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU. Nucleic Acids Res 38: 6219-6233
    • (2010) Nucleic Acids Res , vol.38 , pp. 6219-6233
    • Lattmann, S.1    Giri, B.2    Vaughn, J.P.3    Akman, S.A.4    Nagamine, Y.5
  • 16
    • 33646100776 scopus 로고    scopus 로고
    • A conserved G4 DNA binding domain in RecQ family helicases
    • Huber MD, Duquette ML, Shiels JC, Maizels N, (2006) A conserved G4 DNA binding domain in RecQ family helicases. J Mol Biol 358: 1071-1080
    • (2006) J Mol Biol , vol.358 , pp. 1071-1080
    • Huber, M.D.1    Duquette, M.L.2    Shiels, J.C.3    Maizels, N.4
  • 18
    • 20144364292 scopus 로고    scopus 로고
    • Prevalence of quadruplexes in the human genome
    • Huppert JL, Balasubramanian S, (2005) Prevalence of quadruplexes in the human genome. Nucleic Acids Res 33: 2908-2916
    • (2005) Nucleic Acids Res , vol.33 , pp. 2908-2916
    • Huppert, J.L.1    Balasubramanian, S.2
  • 20
    • 33748519569 scopus 로고    scopus 로고
    • Gene function correlates with potential for G4 DNA formation in the human genome
    • Eddy J, Maizels N, (2006) Gene function correlates with potential for G4 DNA formation in the human genome. Nucleic Acids Res 34: 3887-3896
    • (2006) Nucleic Acids Res , vol.34 , pp. 3887-3896
    • Eddy, J.1    Maizels, N.2
  • 21
    • 84907921282 scopus 로고    scopus 로고
    • Quantification of topological coupling between DNA superhelicity and G-quadruplex formation
    • Selvam S, Koirala D, Yu Z, Mao H, (2014) Quantification of topological coupling between DNA superhelicity and G-quadruplex formation. J Am Chem Soc 136: 13967-13970
    • (2014) J Am Chem Soc , vol.136 , pp. 13967-13970
    • Selvam, S.1    Koirala, D.2    Yu, Z.3    Mao, H.4
  • 22
    • 84891400223 scopus 로고    scopus 로고
    • Existence and consequences of G-quadruplex structures in DNA
    • Murat P, Balasubramanian S, (2014) Existence and consequences of G-quadruplex structures in DNA. Curr Opin Genet Dev 25: 22-29
    • (2014) Curr Opin Genet Dev , vol.25 , pp. 22-29
    • Murat, P.1    Balasubramanian, S.2
  • 24
    • 84897029094 scopus 로고    scopus 로고
    • G quadruplexes are genomewide targets of transcriptional helicases XPB and XPD
    • Gray LT, Vallur AC, Eddy J, Maizels N, (2014) G quadruplexes are genomewide targets of transcriptional helicases XPB and XPD. Nat Chem Biol 10: 313-318
    • (2014) Nat Chem Biol , vol.10 , pp. 313-318
    • Gray, L.T.1    Vallur, A.C.2    Eddy, J.3    Maizels, N.4
  • 25
    • 84903757525 scopus 로고    scopus 로고
    • Sources of DNA double-strand breaks and models of recombinational DNA repair
    • Mehta A, Haber JE, (2014) Sources of DNA double-strand breaks and models of recombinational DNA repair. Cold Spring Harb Perspect Biol 6: a016428
    • (2014) Cold Spring Harb Perspect Biol , vol.6 , pp. a016428
    • Mehta, A.1    Haber, J.E.2
  • 26
    • 45449102827 scopus 로고    scopus 로고
    • Mutagenic capacity of endogenous G4 DNA underlies genome instability in FANCJ-defective C elegans
    • Kruisselbrink E, Guryev V, Brouwer K, Pontier DB, Cuppen E, Tijsterman M, (2008) Mutagenic capacity of endogenous G4 DNA underlies genome instability in FANCJ-defective C. elegans. Curr Biol 18: 900-905
    • (2008) Curr Biol , vol.18 , pp. 900-905
    • Kruisselbrink, E.1    Guryev, V.2    Brouwer, K.3    Pontier, D.B.4    Cuppen, E.5    Tijsterman, M.6
  • 27
    • 47049092433 scopus 로고    scopus 로고
    • Genomic Stability: FANCJ-Dependent G4 DNA Repair
    • Maizels N, (2008) Genomic Stability: FANCJ-Dependent G4 DNA Repair. Curr Biol 18: R613-614
    • (2008) Curr Biol , vol.18 , pp. R613-R614
    • Maizels, N.1
  • 29
    • 84901823399 scopus 로고    scopus 로고
    • Polymerase theta-mediated end joining of replication-associated DNA breaks in C elegans
    • Roerink SF, van Schendel R, Tijsterman M, (2014) Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans. Genome Res 24: 954-962
    • (2014) Genome Res , vol.24 , pp. 954-962
    • Roerink, S.F.1    Van Schendel, R.2    Tijsterman, M.3
  • 30
    • 84919362822 scopus 로고    scopus 로고
    • The repair of G-quadruplex-induced DNA damage
    • van Kregten M, Tijsterman M, (2014) The repair of G-quadruplex-induced DNA damage. Exp Cell Res 329: 178-183
    • (2014) Exp Cell Res , vol.329 , pp. 178-183
    • Van Kregten, M.1    Tijsterman, M.2
  • 32
    • 80053593431 scopus 로고    scopus 로고
    • G4 DNA: At risk in the genome
    • Davis L, Maizels N, (2011) G4 DNA: at risk in the genome. EMBO J 30: 3878-3879
    • (2011) EMBO J , vol.30 , pp. 3878-3879
    • Davis, L.1    Maizels, N.2
  • 33
    • 84870660365 scopus 로고    scopus 로고
    • Stimulation of gross chromosomal rearrangements by the human CEB1 and CEB25 minisatellites in Saccharomyces cerevisiae depends on G-quadruplexes or Cdc13
    • Piazza A, Serero A, Boulé JB, Legoix-Né P, Lopes J, Nicolas A, (2012) Stimulation of gross chromosomal rearrangements by the human CEB1 and CEB25 minisatellites in Saccharomyces cerevisiae depends on G-quadruplexes or Cdc13. PLoS Genet 8: e1003033
    • (2012) PLoS Genet , vol.8 , pp. e1003033
    • Piazza, A.1    Serero, A.2    Boulé, J.B.3    Legoix-Né, P.4    Lopes, J.5    Nicolas, A.6
  • 34
    • 79957556530 scopus 로고    scopus 로고
    • DNA Replication through G-Quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase
    • Paeschke K, Capra JA, Zakian VA, (2011) DNA Replication through G-Quadruplex motifs Is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase. Cell 145: 678-691
    • (2011) Cell , vol.145 , pp. 678-691
    • Paeschke, K.1    Capra, J.A.2    Zakian, V.A.3
  • 35
    • 84928235601 scopus 로고    scopus 로고
    • The essential Schizosaccharomyces pombe Pfh1 DNA helicase promotes fork movement past G-quadruplex motifs to prevent DNA damage
    • Sabouri N, Capra JA, Zakian VA, (2014) The essential Schizosaccharomyces pombe Pfh1 DNA helicase promotes fork movement past G-quadruplex motifs to prevent DNA damage. BMC Biol 12: 101
    • (2014) BMC Biol , vol.12 , pp. 101
    • Sabouri, N.1    Capra, J.A.2    Zakian, V.A.3
  • 36
    • 78049298053 scopus 로고    scopus 로고
    • G-quadruplex DNA sequences are evolutionarily conserved and associated with distinct genomic features in Saccharomyces cerevisiae
    • Capra JA, Paeschke K, Singh M, Zakian VA, (2010) G-quadruplex DNA sequences are evolutionarily conserved and associated with distinct genomic features in Saccharomyces cerevisiae. PLoS Comput Biol 6: e1000861
    • (2010) PLoS Comput Biol , vol.6 , pp. e1000861
    • Capra, J.A.1    Paeschke, K.2    Singh, M.3    Zakian, V.A.4
  • 37
    • 83255189766 scopus 로고    scopus 로고
    • DNA replication timing and long-range DNA interactions predict mutational landscapes of cancer genomes
    • De S, Michor F, (2011) DNA replication timing and long-range DNA interactions predict mutational landscapes of cancer genomes. Nat Biotechnol 29: 1103-1108
    • (2011) Nat Biotechnol , vol.29 , pp. 1103-1108
    • De, S.1    Michor, F.2
  • 38
    • 84902187810 scopus 로고    scopus 로고
    • Human RecQ helicases in DNA repair, recombination, and replication
    • Croteau DL, Popuri V, Opresko PL, Bohr VA, (2014) Human RecQ helicases in DNA repair, recombination, and replication. Annu Rev Biochem 83: 519-552
    • (2014) Annu Rev Biochem , vol.83 , pp. 519-552
    • Croteau, D.L.1    Popuri, V.2    Opresko, P.L.3    Bohr, V.A.4
  • 39
    • 0032538453 scopus 로고    scopus 로고
    • The Bloom's syndrome helicase unwinds G4 DNA
    • Sun H, Karow JK, Hickson ID, Maizels N, (1998) The Bloom's syndrome helicase unwinds G4 DNA. J Biol Chem 273: 27587-27592
    • (1998) J Biol Chem , vol.273 , pp. 27587-27592
    • Sun, H.1    Karow, J.K.2    Hickson, I.D.3    Maizels, N.4
  • 40
    • 84875947376 scopus 로고    scopus 로고
    • Werner syndrome: A changing pattern of clinical manifestations in Japan (1917∼2008)
    • Goto M, Ishikawa Y, Sugimoto M, Furuichi Y, (2013) Werner syndrome: a changing pattern of clinical manifestations in Japan (1917∼2008). Biosci Trends 7: 13-22
    • (2013) Biosci Trends , vol.7 , pp. 13-22
    • Goto, M.1    Ishikawa, Y.2    Sugimoto, M.3    Furuichi, Y.4
  • 41
    • 76749168005 scopus 로고    scopus 로고
    • Roles of Werner syndrome protein in protection of genome integrity
    • Rossi ML, Ghosh AK, Bohr VA, (2010) Roles of Werner syndrome protein in protection of genome integrity. DNA Repair (Amst) 9: 331-344
    • (2010) DNA Repair (Amst) , vol.9 , pp. 331-344
    • Rossi, M.L.1    Ghosh, A.K.2    Bohr, V.A.3
  • 42
    • 84865323382 scopus 로고    scopus 로고
    • Werner syndrome protein suppresses the formation of large deletions during the replication of human telomeric sequences
    • Damerla RR, Knickelbein KE, Strutt S, Liu FJ, Wang H, Opresko PL, (2012) Werner syndrome protein suppresses the formation of large deletions during the replication of human telomeric sequences. Cell Cycle 11: 3036-3044
    • (2012) Cell Cycle , vol.11 , pp. 3036-3044
    • Damerla, R.R.1    Knickelbein, K.E.2    Strutt, S.3    Liu, F.J.4    Wang, H.5    Opresko, P.L.6
  • 43
    • 84870323168 scopus 로고    scopus 로고
    • Structure, function and evolution of the XPD family of iron-sulfur-containing 5′-3′ DNA helicases
    • White MF, (2009) Structure, function and evolution of the XPD family of iron-sulfur-containing 5′-3′ DNA helicases. Biochem Soc Trans 37: 547-551
    • (2009) Biochem Soc Trans , vol.37 , pp. 547-551
    • White, M.F.1
  • 44
    • 84860854071 scopus 로고    scopus 로고
    • RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity
    • Vannier JB, Pavicic-Kaltenbrunner V, Petalcorin MI, Ding H, Boulton SJ, (2012) RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity. Cell 149: 795-806
    • (2012) Cell , vol.149 , pp. 795-806
    • Vannier, J.B.1    Pavicic-Kaltenbrunner, V.2    Petalcorin, M.I.3    Ding, H.4    Boulton, S.J.5
  • 47
    • 84884656362 scopus 로고    scopus 로고
    • A recessive founder mutation in regulator of telomere elongation helicase 1, RTEL1, underlies severe immunodeficiency and features of Hoyeraal Hreidarsson syndrome
    • Ballew BJ, Joseph V, De S, Sarek G, Vannier JB, Stracker T, Schrader KA, Small TN, O'Reilly R, Manschreck C, et al, (2013) A recessive founder mutation in regulator of telomere elongation helicase 1, RTEL1, underlies severe immunodeficiency and features of Hoyeraal Hreidarsson syndrome. PLoS Genet 9: e1003695
    • (2013) PLoS Genet , vol.9 , pp. e1003695
    • Ballew, B.J.1    Joseph, V.2    De, S.3    Sarek, G.4    Vannier, J.B.5    Stracker, T.6    Schrader, K.A.7    Small, T.N.8    O'Reilly, R.9    Manschreck, C.10
  • 50
    • 0041324850 scopus 로고    scopus 로고
    • Telomere instability in a human tumor cell line expressing a dominant-negative WRN protein
    • Bai Y, Murnane JP, (2003) Telomere instability in a human tumor cell line expressing a dominant-negative WRN protein. Hum Genet 113: 337-347
    • (2003) Hum Genet , vol.113 , pp. 337-347
    • Bai, Y.1    Murnane, J.P.2
  • 51
    • 84885628048 scopus 로고    scopus 로고
    • RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication
    • Vannier JB, Sandhu S, Petalcorin MI, Wu X, Nabi Z, Ding H, Boulton SJ, (2013) RTEL1 is a replisome-associated helicase that promotes telomere and genome-wide replication. Science 342: 239-242
    • (2013) Science , vol.342 , pp. 239-242
    • Vannier, J.B.1    Sandhu, S.2    Petalcorin, M.I.3    Wu, X.4    Nabi, Z.5    Ding, H.6    Boulton, S.J.7
  • 53
    • 44949114282 scopus 로고    scopus 로고
    • FANCJ helicase defective in Fanconi anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability
    • Wu Y, Shin-Ya K, Brosh RM Jr, (2008) FANCJ helicase defective in Fanconi anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability. Mol Cell Biol 28: 4116-4128
    • (2008) Mol Cell Biol , vol.28 , pp. 4116-4128
    • Wu, Y.1    Shin-Ya, K.2    Brosh, R.M.3
  • 55
  • 57
    • 34250878426 scopus 로고    scopus 로고
    • Expandable DNA repeats and human disease
    • Mirkin SM, (2007) Expandable DNA repeats and human disease. Nature 447: 932-940
    • (2007) Nature , vol.447 , pp. 932-940
    • Mirkin, S.M.1
  • 58
    • 84856879093 scopus 로고    scopus 로고
    • Molecular Mechanisms of Fragile X Syndrome: A Twenty-Year Perspective
    • Santoro MR, Bray SM, Warren ST, (2011) Molecular Mechanisms of Fragile X Syndrome: A Twenty-Year Perspective. Annu Rev Pathol 7: 219-245
    • (2011) Annu Rev Pathol , vol.7 , pp. 219-245
    • Santoro, M.R.1    Bray, S.M.2    Warren, S.T.3
  • 60
    • 84892149837 scopus 로고    scopus 로고
    • To switch or not to switch: At the origin of repeat expansion disease
    • Mirkin EV, Mirkin SM, (2014) To switch or not to switch: at the origin of repeat expansion disease. Mol Cell 53: 1-3
    • (2014) Mol Cell , vol.53 , pp. 1-3
    • Mirkin, E.V.1    Mirkin, S.M.2
  • 61
    • 84934443796 scopus 로고    scopus 로고
    • Unstable mutations in the FMR1 gene and the phenotypes
    • Loesch D, Hagerman R, (2012) Unstable mutations in the FMR1 gene and the phenotypes. Adv Exp Med Biol 769: 78-114
    • (2012) Adv Exp Med Biol , vol.769 , pp. 78-114
    • Loesch, D.1    Hagerman, R.2
  • 64
    • 84858620858 scopus 로고    scopus 로고
    • C9orf72 repeat expansions in patients with ALS and FTD
    • Rademakers R, (2012) C9orf72 repeat expansions in patients with ALS and FTD. Lancet Neurol 11: 297-298
    • (2012) Lancet Neurol , vol.11 , pp. 297-298
    • Rademakers, R.1
  • 66
    • 84871801926 scopus 로고    scopus 로고
    • C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes
    • Fratta P, Mizielinska S, Nicoll AJ, Zloh M, Fisher EM, Parkinson G, Isaacs AM, (2012) C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes. Sci Rep 2: 1016
    • (2012) Sci Rep , vol.2 , pp. 1016
    • Fratta, P.1    Mizielinska, S.2    Nicoll, A.J.3    Zloh, M.4    Fisher, E.M.5    Parkinson, G.6    Isaacs, A.M.7
  • 71
    • 84896699287 scopus 로고    scopus 로고
    • The widening spectrum of C9ORF72-related disease; Genotype/phenotype correlations and potential modifiers of clinical phenotype
    • Cooper-Knock J, Shaw PJ, Kirby J, (2014) The widening spectrum of C9ORF72-related disease; genotype/phenotype correlations and potential modifiers of clinical phenotype. Acta Neuropathol 127: 333-345
    • (2014) Acta Neuropathol , vol.127 , pp. 333-345
    • Cooper-Knock, J.1    Shaw, P.J.2    Kirby, J.3
  • 72
    • 79959845010 scopus 로고    scopus 로고
    • Nuclear accumulation of stress response mRNAs contributes to the neurodegeneration caused by Fragile X premutation rCGG repeats
    • Qurashi A, Li W, Zhou JY, Peng J, Jin P, (2011) Nuclear accumulation of stress response mRNAs contributes to the neurodegeneration caused by Fragile X premutation rCGG repeats. PLoS Genet 7: e1002102
    • (2011) PLoS Genet , vol.7 , pp. e1002102
    • Qurashi, A.1    Li, W.2    Zhou, J.Y.3    Peng, J.4    Jin, P.5
  • 73
    • 80051549115 scopus 로고    scopus 로고
    • Expansion of intronic GGCCTG hexanucleotide repeat in NOP56 causes SCA36, a type of spinocerebellar ataxia accompanied by motor neuron involvement
    • Kobayashi H, Abe K, Matsuura T, Ikeda Y, Hitomi T, Akechi Y, Habu T, Liu W, Okuda H, Koizumi A, (2011) Expansion of intronic GGCCTG hexanucleotide repeat in NOP56 causes SCA36, a type of spinocerebellar ataxia accompanied by motor neuron involvement. Am J Hum Genet 89: 121-130
    • (2011) Am J Hum Genet , vol.89 , pp. 121-130
    • Kobayashi, H.1    Abe, K.2    Matsuura, T.3    Ikeda, Y.4    Hitomi, T.5    Akechi, Y.6    Habu, T.7    Liu, W.8    Okuda, H.9    Koizumi, A.10
  • 79
    • 0030006902 scopus 로고    scopus 로고
    • Two mutant prion proteins expressed in cultured cells acquire biochemical properties reminiscent of the scrapie isoform
    • Lehmann S, Harris DA, (1996) Two mutant prion proteins expressed in cultured cells acquire biochemical properties reminiscent of the scrapie isoform. Proc Natl Acad Sci USA 93: 5610-5614
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5610-5614
    • Lehmann, S.1    Harris, D.A.2
  • 80
    • 68449102464 scopus 로고    scopus 로고
    • An alternative DNA structure is necessary for pilin antigenic variation in Neisseria gonorrhoeae
    • Cahoon LA, Seifert HS, (2009) An alternative DNA structure is necessary for pilin antigenic variation in Neisseria gonorrhoeae. Science 325: 764-767
    • (2009) Science , vol.325 , pp. 764-767
    • Cahoon, L.A.1    Seifert, H.S.2
  • 81
    • 84874028128 scopus 로고    scopus 로고
    • Transcription of a cis-acting, noncoding, small RNA is required for pilin antigenic variation in Neisseria gonorrhoeae
    • Cahoon LA, Seifert HS, (2013) Transcription of a cis-acting, noncoding, small RNA Is required for pilin antigenic variation in Neisseria gonorrhoeae. PLoS Pathog 9: e1003074
    • (2013) PLoS Pathog , vol.9 , pp. e1003074
    • Cahoon, L.A.1    Seifert, H.S.2
  • 82
    • 84870512221 scopus 로고    scopus 로고
    • RecA-binding pilE G4 sequence essential for pilin antigenic variation forms monomeric and 5′ end-stacked dimeric parallel G-quadruplexes
    • Kuryavyi V, Cahoon LA, Seifert HS, Patel DJ, (2012) RecA-binding pilE G4 sequence essential for pilin antigenic variation forms monomeric and 5′ end-stacked dimeric parallel G-quadruplexes. Structure 20: 2090-2102
    • (2012) Structure , vol.20 , pp. 2090-2102
    • Kuryavyi, V.1    Cahoon, L.A.2    Seifert, H.S.3    Patel, D.J.4
  • 83
    • 84924371169 scopus 로고    scopus 로고
    • G-quadruplexes in pathogens: A common route to virulence control?
    • Harris LM, Merrick CJ, (2015) G-quadruplexes in pathogens: a common route to virulence control? PLoS Pathog 11: e1004562
    • (2015) PLoS Pathog , vol.11 , pp. e1004562
    • Harris, L.M.1    Merrick, C.J.2
  • 84
    • 79960377780 scopus 로고    scopus 로고
    • A history of TFIIH: Two decades of molecular biology on a pivotal transcription/repair factor
    • Egly JM, Coin F, (2011) A history of TFIIH: two decades of molecular biology on a pivotal transcription/repair factor. DNA Repair (Amst) 10: 714-721
    • (2011) DNA Repair (Amst) , vol.10 , pp. 714-721
    • Egly, J.M.1    Coin, F.2
  • 85
    • 84867706701 scopus 로고    scopus 로고
    • Nucleotide excision repair: New tricks with old bricks
    • Kamileri I, Karakasilioti I, Garinis GA, (2012) Nucleotide excision repair: new tricks with old bricks. Trends Genet 28: 566-573
    • (2012) Trends Genet , vol.28 , pp. 566-573
    • Kamileri, I.1    Karakasilioti, I.2    Garinis, G.A.3
  • 87
    • 40249084264 scopus 로고    scopus 로고
    • Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes
    • Eddy J, Maizels N, (2008) Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes. Nucleic Acids Res 36: 1321-1333
    • (2008) Nucleic Acids Res , vol.36 , pp. 1321-1333
    • Eddy, J.1    Maizels, N.2
  • 93
    • 78649980436 scopus 로고    scopus 로고
    • Epigenetic instability due to defective replication of structured DNA
    • Sarkies P, Reams C, Simpson LJ, Sale JE, (2010) Epigenetic instability due to defective replication of structured DNA. Mol Cell 40: 703-713
    • (2010) Mol Cell , vol.40 , pp. 703-713
    • Sarkies, P.1    Reams, C.2    Simpson, L.J.3    Sale, J.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.