Nuclear accumulation of stress response mRNAs contributes to the neurodegeneration caused by fragile X premutation rCGG repeats

PLoS Genetics

Volumn 7, Issue 6, 2011, Pages

  Qurashi, Abrar ^a   Li, Wendi ^a   Zhou, Jian Ying ^a,b   Peng, Junmin ^a   Jin, Peng ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN 70; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A2; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN B1; HU LI TAI SHAO PROTEIN; MESSENGER RNA; PROTEIN; PROTEIN PUR ALPHA; PROTEIN RM62; RNA BINDING PROTEIN; RNA HELICASE; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; DROSOPHILA PROTEIN; FRAGILE X MENTAL RETARDATION PROTEIN; PUR ALPHA PROTEIN, DROSOPHILA; PUR-ALPHA PROTEIN, DROSOPHILA; TRANSCRIPTION FACTOR;

ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DEGENERATIVE DISEASE; DROSOPHILA; FRAGILE X ASSOCIATED TREMOR ATAXIA SYNDROME; GENE; GENE INTERACTION; GENE MUTATION; HU LI TAI SHAO GENE; IMMUNE RESPONSE; NERVE DEGENERATION; NONHUMAN; PATHOGENESIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEOMICS; RCGG REPEAT; RM62 GENE; RNA INTERFERENCE; SMALL BRISTLE GENE; STRESS; TRINUCLEOTIDE REPEAT; WILD TYPE; ANIMAL; FRAGILE X SYNDROME; GENETICS; METABOLISM; MUTATION; NERVE CELL;

ANIMALS; CELL NUCLEUS; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; FRAGILE X MENTAL RETARDATION PROTEIN; FRAGILE X SYNDROME; HSP70 HEAT-SHOCK PROTEINS; MUTATION; NERVE DEGENERATION; NEURONS; RNA, MESSENGER; TRANSCRIPTION FACTORS; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 79959845010     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002102     Document Type: Article

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