RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer.

Nature

Volumn 513, Issue 7516, 2014, Pages 65-70

  Wolfe, Andrew L ^a   Singh, Kamini ^a   Zhong, Y ^a   Drewe, Philipp ^a   Rajasekhar, Vinagolu K ^b   Sanghvi, Viraj R ^a   Mavrakis, Konstantinos J ^b   Jiang, Man ^a   Roderick, Justine E ^a   Van der Meulen, Joni ^a   Schatz, Jonathan H ^b   Rodrigo, Christina M ^a   Zhao, Chunying ^a   Rondou, Pieter ^a   de Stanchina, Elisa ^b   Teruya Feldstein, Julie ^b   Kelliher, Michelle A ^a   Speleman, Frank ^a   Porco Jr , John A ^a   Pelletier, Jerry ^a   Rätsch, Gunnar ^a   Wendel, Hans Guido ^a   more..

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; GUANINE QUADRUPLEX; INITIATION FACTOR 4A; ONCOPROTEIN; SILVESTROL; TRANSCRIPTION FACTOR; TRITERPENE;

5' UNTRANSLATED REGION; ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL; ARTICLE; BIOSYNTHESIS; C57BL MOUSE; DRUG EFFECT; FEMALE; GENETIC EPIGENESIS; GENETIC TRANSCRIPTION; GENETICS; HUMAN; METABOLISM; MOUSE; NUCLEOTIDE MOTIF; NUCLEOTIDE SEQUENCE; PROTEIN SYNTHESIS; RIBOSOME; TUMOR CELL LINE;

5' UNTRANSLATED REGIONS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BASE SEQUENCE; CELL LINE, TUMOR; EPIGENESIS, GENETIC; EUKARYOTIC INITIATION FACTOR-4A; FEMALE; G-QUADRUPLEXES; HUMANS; MICE; MICE, INBRED C57BL; NUCLEOTIDE MOTIFS; ONCOGENE PROTEINS; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTEIN BIOSYNTHESIS; RIBOSOMES; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRITERPENES;

EID: 84907221438     PISSN: None     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13485     Document Type: Article

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