Hydrophilic polymers for modified-release nanoparticles: A review of mathematical modelling for pharmacokinetic analysis

Current Pharmaceutical Design

Volumn 21, Issue 22, 2015, Pages 3090-3096

  Andreani, Tatiana ^a,b   Fangueiro, Joana F ^b,c   José, Sajan ^d   Santini, Antonello ^e   Silva, Amélia M ^a,b   Souto, Eliana B ^f  

^a UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

^b UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d MAHATMA GANDHI UNIVERSITY   (India)

^e UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^f UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Hydrophilic polymers; Mathematic modelling; Modified release nanoparticles; Pharmacokinetics

Indexed keywords

MODIFIED RELEASE NANOPARTICLE; NANOPARTICLE; POLYMER; UNCLASSIFIED DRUG; DRUG CARRIER;

BIOEQUIVALENCE; DIFFUSION COEFFICIENT; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG SOLUBILITY; HYDROPHILICITY; IN VIVO STUDY; MATHEMATICAL MODEL; PARTICLE SIZE; PHARMACOKINETICS; PREDICTION; PRIORITY JOURNAL; REVIEW; BIOAVAILABILITY; BIOLOGICAL MODEL; CHEMICAL PHENOMENA; CHEMISTRY;

BIOLOGICAL AVAILABILITY; DRUG CARRIERS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, BIOLOGICAL; NANOPARTICLES; PHARMACOKINETICS; POLYMERS;

EID: 84938650711     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612821666150531163617     Document Type: Review

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