PH-dependent, thermosensitive polymeric nanocarriers for drug delivery to solid tumors

Biomaterials

Volumn 34, Issue 18, 2013, Pages 4501-4509

  Chen, Ching Yi ^a,d   Kim, Tae Hee ^b,e   Wu, Wen Chung ^a,c   Huang, Chi Ming ^c   Wei, Hua ^b   Mount, Christopher W ^b   Tian, Yanqing ^a,f   Jang, Sei Hum ^a   Pun, Suzie H ^b   Jen, Alex K Y ^a  

^a University of Washington   (United States)

^b University of Washington   (United States)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^d NATIONAL CHUNG CHENG UNIVERSITY   (Taiwan)

^e Korea Institute of Industrial Technology   (South Korea)

^f ARIZONA STATE UNIVERSITY   (United States)

Author keywords

Anti cancer; PH sensitive; Polymeric micelle; Temperature sensitive; Tumor delivery

Indexed keywords

ANTI-CANCER; PH SENSITIVE; PH- AND TEMPERATURE-RESPONSIVE; POLYMERIC MICELLE; POLYMERIC NANOCARRIERS; STIMULI-RESPONSIVE MATERIALS; TEMPERATURE SENSITIVE; TUMOR XENOGRAFT MODELS;

AMINO ACIDS; BLOCK COPOLYMERS; CARDIOVASCULAR SYSTEM; DISEASES; DRUG DELIVERY; MICELLES; TUMORS;

POLYMERS;

AMINO ACID; AMINOCAPROIC ACID; COPOLYMER; DOXORUBICIN; MONOMER; NANOCARRIER; POLYCAPROLACTONE; POLYMER; TRIETHYLENE GLYCOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; BLOOD PH; BODY TEMPERATURE; DRUG DELIVERY SYSTEM; HEAT SENSITIVITY; HUMAN; HUMAN CELL; HYDROPHOBICITY; MALE; MICELLE; MOUSE; NONHUMAN; PHASE TRANSITION; PRIORITY JOURNAL; SOLID TUMOR; TEMPERATURE; TUMOR XENOGRAFT;

6-AMINOCAPROIC ACID; ANIMALS; CELL LINE, TUMOR; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HUMANS; HYDROGEN-ION CONCENTRATION; INHIBITORY CONCENTRATION 50; INJECTIONS; KINETICS; LIGHT; MALE; MICE; MICE, NUDE; MICELLES; NANOPARTICLES; NEOPLASMS; PARTICLE SIZE; POLYESTERS; POLYETHYLENE GLYCOLS; POLYMERS; SCATTERING, RADIATION; TEMPERATURE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS;

EID: 84875633511     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.02.049     Document Type: Article

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