In vivo pharmacokinetics and biodistribution of resveratrol-loaded solid lipid nanoparticles for brain delivery

International Journal of Pharmaceutics

Volumn 474, Issue 1-2, 2014, Pages 6-13

  Jose, S ^a   Anju, S S ^a   Cinu, T A ^a,b   Aleykutty, N A ^a   Thomas, S ^a   Souto, E B ^c,d  

^a MAHATMA GANDHI UNIVERSITY   (India)

^b MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

^c UNIVERSIDADE FERNANDO PESSOA   (Portugal)

^d UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

Author keywords

Brain cancer; Brain targeting; Cytotoxicity; Resveratrol; Solid lipid nanoparticles (SLN)

Indexed keywords

GLYCEROL BEHENATE; PHOSPHATE; POLYSORBATE 80; POLYVINYL ALCOHOL; RESVERATROL; SOLID LIPID NANOPARTICLE; ANTINEOPLASTIC AGENT; LIPID; NANOPARTICLE; STILBENE DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN TISSUE; CANCER INHIBITION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY ASSAY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STORAGE; DRUG TRANSFORMATION; ENDOTHELIUM CELL; ENTHALPY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY; LIVER; LUNG; NANOEMULSION; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PH; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; SPLEEN; SURFACE CHARGE; SURFACE PROPERTY; SUSTAINED DRUG RELEASE; TISSUE HOMOGENATE; ULTRAVIOLET DETECTOR; X RAY DIFFRACTION; ZETA POTENTIAL; ANIMAL; BRAIN; CELL PROLIFERATION; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; HUMAN; INTRAPERITONEAL DRUG ADMINISTRATION; METABOLISM; STRUCTURE ACTIVITY RELATION; TISSUE DISTRIBUTION; TUMOR CELL LINE; WISTAR RAT; ANTINEOPLASTIC ACTIVITY; DRUG ACCUMULATION; DRUG RELEASE; GLIOMA CELL; HUMAN CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; BRAIN; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; INJECTIONS, INTRAPERITONEAL; LIPIDS; NANOPARTICLES; RATS; RATS, WISTAR; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP; TISSUE DISTRIBUTION;

EID: 84905819966     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.08.003     Document Type: Article

References (43)

1. M. Asensi, I. Medina, A. Ortega, J. Carretero, M.C. Baño, E. Obrador, and J.M. Estrela Inhibition of cancer growth by resveratrol is related to its low bioavailability Free Radic. Biol. Med. 33 2002 387 398 (Pubitemid 34786278)
2. R.D. Baird, and S.B. Kaye Drug resistance reversal - are we getting closer Eur. J. Cancer 39 2003 2450 2461 (Pubitemid 37340159)
3. R. Bhatt, D. Singh, A. Prakash, and N. Mishra Development, characterization and nasal delivery of rosmarinic acid-loaded solid lipid nanoparticles for the effective management of Huntington's disease Drug Deliv. February 2014 (Epub ahead of print)
4. P. Blasi, S. Giovagnoli, A. Schoubben, M. Ricci, and C. Rossi Solid lipid nanoparticles for targeted brain drug delivery Adv. Drug Deliv. Rev. 59 2007 454 477 (Pubitemid 47259226)
5. L. Bu, L.C. Gan, X.Q. Guo, F.Z. Chen, Q. Song, Z. Qi, X.J. Gou, S.X. Hou, and Q. Yao Trans-resveratrol loaded chitosan nanoparticles modified with biotin and avidin to target hepatic carcinoma Int. J. Pharm. 452 2013 355 362
6. P.G. Cadena, M.A. Pereira, R.B. Cordeiro, I.M. Cavalcanti, B. Barros Neto, C. Pimentel Mdo, J.L. Lima Filho, V.L. Silva, and N.S. Santos-Magalhaes Nanoencapsulation of quercetin and resveratrol into elastic liposomes Biochim. Biophys. Acta 1828 2013 309 316
7. C.H. Cottart, V. Nivet-Antoine, C. Laguillier-Morizot, and J.L. Beaudeux Resveratrol bioavailability and toxicity in humans Mol. Nutr. Food Res. 54 2010 7 16
8. S. Doktorovova, D.L. Santos, I. Costa, T. Andreani, E.B. Souto, and A.M. Silva Cationic solid lipid nanoparticles interfere with the activity of antioxidant enzymes in hepatocellular carcinoma cells Int. J. Pharm. 471 2014 18 27
9. S. Doktorovova, A.M. Silva, I. Gaivao, E.B. Souto, J.P. Teixeira, and P. Martins-Lopes Comet assay reveals no genotoxicity risk of cationic solid lipid nanoparticles J. Appl. Toxicol. 34 2014 395 403
10. S. Doktorovova, E.B. Souto, and A.M. Silva Nanotoxicology applied to solid lipid nanoparticles and nanostructured lipid carriers - a systematic review of in vitro data Eur. J. Pharm. Biopharm. 87 2014 1 18
11. A. Estella-Hermoso de Mendoza, V. Préat, F. Mollinedo, and M.J. Blanco-Prieto In vitro and in vivo efficacy of edelfosine-loaded lipid nanoparticles against glioma J. Control. Release 156 2011 421 426
12. F. Felice, Y. Zambito, E. Belardinelli, C. D'Onofrio, A. Fabiano, A. Balbarini, and R. Di Stefano Delivery of natural polyphenols by polymeric nanoparticles improves the resistance of endothelial progenitor cells to oxidative stress Eur. J. Pharm. Sci. 50 2013 393 399
13. F. Figueiro, A. Bernardi, R.L. Frozza, T. Terroso, A. Zanotto-Filho, E.H. Jandrey, J.C. Moreira, C.G. Salbego, M.I. Edelweiss, A.R. Pohlmann, S.S. Guterres, and A.M. Battastini Resveratrol-loaded lipid-core nanocapsules treatment reduces in vitro and in vivo glioma growth J. Biomed. Nanotechnol. 9 2013 516 526
14. J.L. Fisher, J.A. Schwartzbaum, M. Wrensch, and J.L. Wiemels Epidemiology of brain tumors Neurol. Clin. 25 2007 867 890 vii. (Pubitemid 47603275)
15. D.M. Goldberg, J. Yan, and G.J. Soleas Absorption of three wine-related polyphenols in three different matrices by healthy subjects Clin. Biochem. 36 2003 79 87 (Pubitemid 36126394)
16. W. Guo, A. Li, Z. Jia, Y. Yuan, H. Dai, and H. Li 2013. Transferrin modified PEG-PLA-resveratrol conjugates: in vitro and in vivo studies for glioma Eur. J. Pharmacol. 718 October (1-3) 2013 41 47 10.1016/j.ejphar.2013.09.034 (Epub 2013 September 23)
17. H. He, X. Chen, G. Wang, J. Wang, and A.K. Davey High-performance liquid chromatography spectrometric analysis of trans-resveratrol in rat plasma J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 832 2006 177 180 (Pubitemid 43339942)
18. M. Jang, L. Cai, G.O. Udeani, K.V. Slowing, C.F. Thomas, C.W. Beecher, H.H. Fong, N.R. Farnsworth, A.D. Kinghorn, R.G. Mehta, R.C. Moon, and J.M. Pezzuto Cancer chemopreventive activity of resveratrol, a natural product derived from grapes Science 275 1997 218 220 (Pubitemid 127696281)
19. M. Jang, and J.M. Pezzuto Cancer chemopreventive activity of resveratrol Drugs Exp. Clin. Res. 25 1999 65 77 (Pubitemid 29257597)
20. S. Jose, J.F. Fangueiro, J. Smitha, T.A. Cinu, A.J. Chacko, K. Premaletha, and E.B. Souto Predictive modeling of insulin release profile from cross-linked chitosan microspheres Eur. J. Med. Chem. 60 2013 249 253
21. M.D. Joshi, and R.H. Muller Lipid nanoparticles for parenteral delivery of actives Eur. J. Pharm. Biopharm. 71 2009 161 172
22. P. Kleihues, and W. Cavanee WHO classification of tumors W. Cavanee, Pathology and Genetics 2000 IARC Press Lyon
23. J.K. Kundu, and Y.J. Surh Cancer chemo preventive and therapeutic potential of resveratrol: mechanistic prospective Cancer Lett. 269 2008 243 261
24. M. Li, H. Deng, H. Peng, and Q. Wang Functional nanoparticles in targeting glioma diagnosis and therapies J. Nanosci. Nanotechnol. 14 2014 415 432
25. A. Lippacher, R.H. Muller, and K. Mader Preparation of semisolid drug carriers for topical application based on solid lipid nanoparticles Int. J. Pharm. 214 2001 9 12 (Pubitemid 32244069)
26. A. Lippacher, R.H. Muller, and K. Mader Semisolid SLN dispersions for topical application: influence of formulation and production parameters on viscoelastic properties Eur. J. Pharm. Biopharm. 53 2002 155 160 (Pubitemid 34189788)
27. L. Maletinska, E.A. Blakely, K.A. Bjornstad, D.F. Deen, L.J. Knoff, and T.M. Forte Human glioblastoma cell lines: levels of low-density lipoprotein receptor and low-density lipoprotein receptor-related protein Cancer Res. 60 2000 2300 2303 (Pubitemid 30225197)
28. J.F. Marier, P. Vachon, A. Gritsas, J. Zhang, J.P. Moreau, and M.P. Ducharme Metabolism and disposition of resveratrol in rats: extent of absorption, glucuronidation, and enterohepatic recirculation evidenced by a linked-rat model J. Pharmacol. Exp. Ther. 302 2002 369 373 (Pubitemid 34680460)
29. A. Martirosyan, A. Bazes, and Y.J. Schneider In vitro toxicity assessment of silver nanoparticles in the presence of phenolic compounds - preventive agents against the harmful effect? Nanotoxicology 8 August (5) 2014 573 582 10.3109/17435390.2013.812258 (Epub 2013 June 27)
30. A. Mukerjee Formulation, characterization and evaluation of curcumin-loaded PLGA nanospheres for cancer therapy Anticancer Res. 29 2009 3867 3875
31. R.H. Muller, K. Mader, and S. Gohla Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art Eur. J. Pharm. Biopharm. 50 2000 161 177 (Pubitemid 30326695)
32. A.R. Neves, M. Lucio, S. Martins, J.L. Lima, and S. Reis Novel resveratrol nanodelivery systems based on lipid nanoparticles to enhance its oral bioavailability Int. J. Nanomed. 8 2013 177 187
33. C. Qi, Y. Chen, Q.Z. Jing, and X.G. Wang Preparation and characterization of catalase-loaded solid lipid nanoparticles protecting enzyme against proteolysis Int. J. Mol. Sci. 12 2011 4282 4293
34. S. Reagan-Shaw, M. Nihal, and N. Ahmad Dose translation from animal to human studies revisited FASEB J. 22 2008 659 661 (Pubitemid 351348146)
35. V. Sanna, I.A. Siddiqui, M. Sechi, and H. Mukhtar Resveratrol-loaded nanoparticles based on poly(epsilon-caprolactone) and poly(d,l-lactic-co- glycolic acid)-poly(ethylene glycol) blend for prostate cancer treatment Mol. Pharm. 10 2013 3871 3881
36. P. Severino, T. Andreani, A. Jager, M.V. Chaud, M.H. Santana, A.M. Silva, and E.B. Souto Solid lipid nanoparticles for hydrophilic biotech drugs: optimization and cell viability studies (Caco-2 & HEPG-2 cell lines) Eur. J. Med. Chem. 81 2014 28 34
37. R.K. Subedi, K.W. Kang, and H.K. Choi Preparation and characterization of solid lipid nanoparticles loaded with doxorubicin Eur. J. Pharm. Sci. 37 2009 508 513
38. P.R. van Ginkel, D. Sareen, L. Subramanian, Q. Walker, S.R. Darjatmoko, M.J. Lindstrom, A. Kulkarni, D.M. Albert, and A.S. Polans Resveratrol inhibits tumor growth of human neuroblastoma and mediates apoptosis by directly targeting mitochondria Clin. Cancer Res. 13 2007 5162 5169 (Pubitemid 47502085)
39. T. Walle, F. Hsieh, M.H. DeLegge, J.E. Oatis Jr., and U.K. Walle High absorption but very low bioavailability of oral resveratrol in humans Drug Metab. Dispos. 32 2004 1377 1382 (Pubitemid 39564557)
40. H.L. Wong, N. Chattopadhyay, X.Y. Wu, and R. Bendayan Nanotechnology applications for improved delivery of antiretroviral drugs to the brain Adv. Drug Deliv. Rev. 62 2010 503 517
41. H.L. Wong, X.Y. Wu, and R. Bendayan Nanotechnological advances for the delivery of CNS therapeutics Adv. Drug Deliv. Rev. 64 2012 686 700
42. Z. Xu, L. Chen, W. Gu, Y. Gao, L. Lin, Z. Zhang, Y. Xi, and Y. Li The performance of docetaxel-loaded solid lipid nanoparticles targeted to hepatocellular carcinoma Biomaterials 30 2009 226 232
43. J.S. Young, J.W. Kim, A.U. Ahmed, and M.S. Lesniak Therapeutic cell carriers: a potential road to cure glioma Expert Rev. Neurother. 14 2014 651 660