Interrogating erosion-based drug liberation phenomena from hydrophilic matrices using near infrared (NIR) spectroscopy

European Journal of Pharmaceutical Sciences

Volumn 48, Issue 1-2, 2013, Pages 72-79

  Avalle, Paolo ^a,c   Pygall, Samuel R ^a   Pritchard, Jonathan ^b   Jastrzemska, Agnieszka ^a  

^a MSD   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c MSD Werthenstein Biopharma ^*  (Switzerland)

Author keywords

Chemical imaging; Drug release; HPMC; Hydrophilic matrix; NIR

Indexed keywords

HYDROXYPROPYLMETHYLCELLULOSE;

AQUEOUS SOLUTION; ARTICLE; CONCENTRATION (PARAMETERS); DRUG RELEASE; DRUG SOLUBILITY; GEL; HYDRATION; HYDROPHILICITY; INFRARED SPECTROSCOPY; PRIORITY JOURNAL;

CELLULOSE; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LACTOSE; METHYLCELLULOSE; PHARMACEUTICAL PREPARATIONS; SPECTROSCOPY, NEAR-INFRARED; STEARIC ACIDS; TABLETS; WATER;

EID: 84869876340     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.09.010     Document Type: Article

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