A new approach combining different MRI methods to provide detailed view on swelling dynamics of xanthan tablets influencing drug release at different pH and ionic strength

Journal of Controlled Release

Volumn 145, Issue 3, 2010, Pages 247-256

  Mikac, Urša ^a   Sepe, Ana ^a   Kristl, Julijana ^b   Baumgartner, Saša ^b  

^a JO EF STEFAN INSTITUTE   (Slovenia)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

Bio responsive polymer; Drug release; Magnetic resonance imaging; Matrix tablets; Nuclear magnetic resonance; Swelling; Xanthan

Indexed keywords

BIO-RESPONSIVE POLYMER; DRUG DISSOLUTION; DRUG RELEASE; DRUG RELEASE KINETICS; DYNAMIC PROCESS; GEL FORMATION; GEL LAYERS; GEL STRUCTURES; HYDRODYNAMIC RADIUS; HYDROPHILIC MATRIX; KEY ELEMENTS; MOLECULAR CONFORMATION; MR IMAGES; NEW APPROACHES; PENTOXIFYLLINE; PHYSIOLOGICAL CONDITION; POLYMER SWELLING; RESPONSIVE POLYMER; RUBBERY STATE; SIGNAL INTENSITIES; SINGLE POINT IMAGING; STANDARD METHOD; STRUCTURAL CHANGE;

DISSOLUTION; DRUG PRODUCTS; GELS; HYDRATES; INTERCHANGES; IONIC STRENGTH; IONIZATION OF LIQUIDS; MAGNETIC MATERIALS; MAGNETIC RESONANCE IMAGING; MAGNETISM; NUCLEAR MAGNETIC RESONANCE; POLYMERS; RESONANCE; SWELLING;

PH EFFECTS;

PENTOXIFYLLINE; XANTHAN; BACTERIAL POLYSACCHARIDE; DRUG; DRUG CARRIER; GEL; TABLET;

ARTICLE; DRUG DIFFUSION; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; DRUG SOLUBILITY; GEL; HYDROPHILICITY; IONIC STRENGTH; NUCLEAR MAGNETIC RESONANCE IMAGING; PH; PRIORITY JOURNAL; TABLET MATRIX; CHEMISTRY; OSMOLARITY; PROCEDURES; TABLET;

DRUG CARRIERS; GELS; MAGNETIC RESONANCE IMAGING; OSMOLAR CONCENTRATION; PHARMACEUTICAL PREPARATIONS; POLYSACCHARIDES, BACTERIAL; TABLETS;

EID: 77954312507     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.04.018     Document Type: Article

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