Predictive modeling of insulin release profile from cross-linked chitosan microspheres

European Journal of Medicinal Chemistry

Volumn 60, Issue , 2013, Pages 249-253

  Jose, S ^a   Fangueiro, J F ^b   Smitha, J ^a   Cinu, T A ^a   Chacko, A J ^a   Premaletha, K ^c   Souto, E B ^b,d  

^a MAHATMA GANDHI UNIVERSITY   (India)

^b UNIVERSIDADE FERNANDO PESSOA   (Portugal)

^c Academy of Pharmaceutical Sciences   (India)

^d UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

Author keywords

Bacitracin; Chitosan; Higuchi model; Insulin; Korsmeyer Peppas model microspheres; Medicinal chemistry; Non Fickian diffusion; Oral delivery

Indexed keywords

BACITRACIN; CHITOSAN; INSULIN; MICROSPHERE; TAUROCHOLIC ACID;

ABSORPTION; ARTICLE; BIOLOGICAL ACTIVITY; CROSS LINKING; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SOLUBILITY; HYDROGEN BOND; IN VITRO STUDY; INSULIN DEGRADATION; MOLECULAR MODEL; PARTICLE SIZE; PH; PROTON TRANSPORT;

CHITOSAN; CROSS-LINKING REAGENTS; HYDROGEN-ION CONCENTRATION; INSULIN; KINETICS; MICROSPHERES; MODELS, MOLECULAR; PARTICLE SIZE; SURFACE PROPERTIES;

EID: 84872107577     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.12.011     Document Type: Article

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