-
1
-
-
0032474222
-
Hereditary breast cancer, circa 1750 [13]
-
F Eisinger, H Sobol, D Serin and JC Whorton: Hereditary breast cancer, circa 1750. Lancet 351, 1366 (1998). (Pubitemid 28195936)
-
(1998)
Lancet
, vol.351
, Issue.9112
, pp. 1366
-
-
Eisinger, F.1
Sobol, H.2
Serin, D.3
Whorton, J.C.4
-
3
-
-
0025613812
-
Linkage of early-onset familial breast cancer to chromosome 17q21
-
JM Hall, MK Lee, B Newman, JE Morrow, LA Anderson, B Huey and MC King: Linkage of early-onset familial breast cancer to chromosome 17q21. Science 250, 1684-1689 (1990). (Pubitemid 120031871)
-
(1990)
Science
, vol.250
, Issue.4988
, pp. 1684-1689
-
-
Hall, J.M.1
Lee, M.K.2
Newman, B.3
Morrow, J.E.4
Anderson, L.A.5
Huey, B.6
King, M.-C.7
-
4
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
Y Miki, J Swensen, D Shattuck-Eidens, PA Futreal, K Harshman, S Tavtigian, Q Liu, C Cochran, LM Bennett and W Ding: A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 266, 66-71 (1994). (Pubitemid 24345325)
-
(1994)
Science
, vol.266
, Issue.5182
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
Futreal, P.A.4
Harshman, K.5
Tavtigian, S.6
Liu, Q.7
Cochran, C.8
Bennett, L.M.9
Ding, W.10
Bell, R.11
Rosenthal, J.12
Hussey, C.13
Tran, T.14
McClure, M.15
Frye, C.16
Hattier, T.17
Phelps, R.18
Haugen-Strano, A.19
Katcher, H.20
Yakumo, K.21
Gholami, Z.22
Shaffer, D.23
Stone, S.24
Bayer, S.25
Wray, C.26
Bogden, R.27
Dayananth, P.28
Ward, J.29
Tonin, P.30
Narod, S.31
Bristow, P.K.32
Norris, F.H.33
Helvering, L.34
Morrison, P.35
Rosteck, P.36
Lai, M.37
Barrett, J.C.38
Lewis, C.39
Neuhausen, S.40
Cannon-Albright, L.41
Goldgar, D.42
Wiseman, R.43
Kamb, A.44
Skolnick, M.H.45
more..
-
5
-
-
0028006563
-
Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13
-
R Wooster, SL Neuhausen, J Mangion, Y Quirk, D Ford, N Collins, K Nguyen, S Seal, T Tran and D Averill: Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13. Science 265, 2088-2090 (1994). (Pubitemid 24325690)
-
(1994)
Science
, vol.265
, Issue.5181
, pp. 2088-2090
-
-
Wooster, R.1
Neuhausen, S.L.2
Mangion, J.3
Quirk, Y.4
Ford, D.5
Collins, N.6
Nguyen, K.7
Seal, S.8
Tran, T.9
Averill, D.10
Fields, P.11
-
6
-
-
0006713602
-
Identification of the breast cancer susceptibility gene BRCA2
-
DOI 10.1038/378789a0
-
R Wooster, G Bignell, J Lancaster, S Swift, S Seal, J Mangion, N Collins, S Gregory, C Gumbs and G Micklem: Identification of the breast cancer susceptibility gene BRCA2. Nature 378, 789-792 (1995). (Pubitemid 26004412)
-
(1995)
Nature
, vol.378
, Issue.6559
, pp. 789-792
-
-
Wooster, R.1
Bignell, G.2
Lancaster, J.3
Swift, S.4
Seal, S.5
Mangion, J.6
Collins, N.7
Gregory, S.8
Gumbs, C.9
Micklem, G.10
Barfoot, R.11
Hamoudl, R.12
Patel, S.13
Rice, C.14
Biggs, P.15
Hashim, Y.16
Smith, A.17
Connor, F.18
Arason, A.19
-
7
-
-
33646570913
-
Breast Cancer Susceptibility Collaboration (UK), N Rahman and M RStratton: A genome wide linkage search for breast cancer susceptibility genes
-
P Smith, L McGuffog, DF Easton, GJ Mann, GM Pupo, B Newman, G Chenevix-Trench, kConFab Investigators, C Szabo, M Southey, H Renard, F Odefrey, H Lynch, D Stoppa-Lyonnet, F Couch, JL Hopper, GG Giles, MR McCredie, S Buys, I Andrulis, R Senie, B C G BCFS, DE Goldgar, R Oldenburg, K Kroeze-Jansema, J Kraan, H Meijers-Heijboer, JG Klijn, C van Asperen, I van Leeuwen, HF Vasen, CJ Cornelisse, P Devilee, L Baskcomb, S Seal, R Barfoot, J Mangion, A Hall, S Edkins, E Rapley, R Wooster, J Chang-Claude, D Eccles, DG Evans, PA Futreal, KL Nathanson, BL Weber, Breast Cancer Susceptibility Collaboration (UK), N Rahman and M RStratton: A genome wide linkage search for breast cancer susceptibility genes. Genes Chromosomes Cancer. 45, 646-655 (2006).
-
(2006)
Genes Chromosomes Cancer
, vol.45
, pp. 646-655
-
-
Smith, P.1
Mcguffog, L.2
Easton, D.F.3
Mann, G.J.4
Pupo, G.M.5
Newman, B.6
Chenevix-Trench, G.7
Szabo, C.8
Southey, M.9
Renard, H.10
-
8
-
-
0037194410
-
Heritable breast cancer in twins
-
TM Mack, AS Hamilton, F Press, A Diep and EB Rappaport: Heritable breast cancer in twins. Br J Cancer 87, 294-300 (2002).
-
(2002)
Br J Cancer
, vol.87
, pp. 294-300
-
-
Mack, T.M.1
Hamilton, A.S.2
Press, F.3
Diep, A.4
Rappaport, E.B.5
-
9
-
-
33749002551
-
Models of genetic susceptibility to breast cancer
-
DOI 10.1038/sj.onc.1209879, PII 1209879
-
AC Antoniou and DF Easton: Models of genetic susceptibility to breast cancer. Oncogene 25, 5898-5905 (2006). (Pubitemid 44453445)
-
(2006)
Oncogene
, vol.25
, Issue.43
, pp. 5898-5905
-
-
Antoniou, A.C.1
Easton, D.F.2
-
10
-
-
33749023326
-
The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability
-
DOI 10.1038/sj.onc.1209874, PII 1209874
-
K Gudmundsdottir and A Ashworth: The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability. Oncogene 25, 5864-5874 (2006). (Pubitemid 44453442)
-
(2006)
Oncogene
, vol.25
, Issue.43
, pp. 5864-5874
-
-
Gudmundsdottir, K.1
Ashworth, A.2
-
11
-
-
84862875408
-
BRCA1 tumor suppressor network: Focusing on its tail
-
6-3701-2-6
-
B Wang, BRCA1 tumor suppressor network: focusing on its tail. Cell Biosci 2, 6-3701-2-6 (2012).
-
(2012)
Cell Biosci
, vol.2
-
-
Wang, B.1
-
12
-
-
84864106481
-
Dynamic coregulatory complex containing BRCA1, E2F1 and CtIP controls ATM transcription
-
C Moiola, P De Luca, J Cotignola, K Gardner, E Vazquez and A De Siervi: Dynamic coregulatory complex containing BRCA1, E2F1 and CtIP controls ATM transcription. Cell Physiol Biochem 30, 596-608 (2012).
-
(2012)
Cell Physiol Biochem
, vol.30
, pp. 596-608
-
-
Moiola, C.1
De Luca, P.2
Cotignola, J.3
Gardner, K.4
Vazquez, E.5
De Siervi, A.6
-
13
-
-
76549122939
-
Transcriptional autoregulation by BRCA1
-
A De Siervi, P De Luca, JS Byun, LJ Di, T Fufa, CM Haggerty, E Vazquez, C Moiola, DL Longo and K Gardner: Transcriptional autoregulation by BRCA1. Cancer Res 70, 532-542 (2010).
-
(2010)
Cancer Res
, vol.70
, pp. 532-542
-
-
De Siervi, A.1
De Luca, P.2
Byun, J.S.3
Di, L.J.4
Fufa, T.5
Haggerty, C.M.6
Vazquez, E.7
Moiola, C.8
Longo, D.L.9
Gardner, K.10
-
14
-
-
77953952646
-
BRCA1 and BRCA2: Breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair
-
PJ O'Donovan and DM Livingston: BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair. Carcinogenesis 31, 961-967 (2010).
-
(2010)
Carcinogenesis
, vol.31
, pp. 961-967
-
-
O'donovan, P.J.1
Livingston, D.M.2
-
15
-
-
56249103144
-
Inherited susceptibility to common cancers
-
WD Foulkes: Inherited susceptibility to common cancers. N Engl J Med 359(20):2143-53 (2008).
-
(2008)
N Engl J Med
, vol.359
, Issue.20
, pp. 2143-2153
-
-
Foulkes, W.D.1
-
16
-
-
84858814526
-
Unravelling modifiers of breast and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers: Update on genetic modifiers
-
DR Barnes, AC Antoniou: Unravelling modifiers of breast and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers: update on genetic modifiers. J Intern Med 271(4):331-343 (2012).
-
(2012)
J Intern Med
, vol.271
, Issue.4
, pp. 331-343
-
-
Barnes, D.R.1
Antoniou, A.C.2
-
17
-
-
0033523268
-
Breast Cancer Linkage Consortium: Cancer risks in BRCA2 mutation carriers
-
Breast Cancer Linkage Consortium: Cancer risks in BRCA2 mutation carriers. J Natl Cancer Inst 91: 1310-1316. (1999).
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1310-1316
-
-
-
18
-
-
41649097333
-
Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers
-
Kathleen Cuningham Consortium for Research into Familial Breast Cancer, Swedish BRCA1 and BRCA2 study collaborators, DNA-HEBON collaborators, GEMO, and CIMBA,EMBRACE
-
AC Antoniou, AB Spurdle, OM Sinilnikova, SHealey, KA Pooley, RK Schmutzler, B Versmold, C Engel, A Meindl, N Arnold, W Hofmann, C Sutter, D Niederacher, H Deissler, T Caldes, K Kampjarvi, H Nevanlinna, J Simard, J Beesley, X Chen, Kathleen Cuningham Consortium for Research into Familial Breast Cancer, SL Neuhausen, TR Rebbeck, T Wagner, HT Lynch, C Isaacs, J Weitzel, PA Ganz, MB Daly, G Tomlinson, OI Olopade, JL Blum, FJ Couch, P Peterlongo, S Manoukian, M Barile, P Radice, CI Szabo, LH Pereira, MH Greene, G Rennert, F Lejbkowicz, O Barnett-Griness, IL Andrulis, H Ozcelik, OCGN, AM Gerdes, MA Caligo, Y Laitman, B Kaufman, R Milgrom, E Friedman, Swedish BRCA1 and BRCA2 study collaborators, SM Domchek, KL Nathanson, A Osorio, G Llort, RL Milne, J Benitez, U Hamann, FB Hogervorst, P Manders, MJ Ligtenberg, AM van den Ouweland, DNA-HEBON collaborators, S Peock, M Cook, R Platte, DG Evans, R Eeles, G Pichert, C Chu, D Eccles, R Davidson, F Douglas, EMBRACE, AK Godwin, L Barjhoux, S Mazoyer, H Sobol, V Bourdon, F Eisinger, A Chompret, C Capoulade, B Bressac-de Paillerets, GM Lenoir, M Gauthier-Villars, C Houdayer, D Stoppa-Lyonnet, GEMO, G Chenevix-Trench, DF Easton and CIMBA: Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers. Am J Hum Genet 82, 937-948 (2008).
-
(2008)
Am J Hum Genet
, vol.82
, pp. 937-948
-
-
Antoniou, A.C.1
Spurdle, A.B.2
Sinilnikova, O.M.3
Healey, S.4
Pooley, K.A.5
Schmutzler, R.K.6
Versmold, B.7
Engel, C.8
Meindl, A.9
Arnold, N.10
Hofmann, W.11
Sutter, C.12
Niederacher, D.13
Deissler, H.14
Caldes, T.15
Kampjarvi, K.16
Nevanlinna, H.17
Simard, J.18
Beesley, J.19
Chen, X.20
Neuhausen, S.L.21
Rebbeck, T.R.22
Wagner, T.23
Lynch, H.T.24
Isaacs, C.25
Weitzel, J.26
Ganz, P.A.27
Daly, M.B.28
Tomlinson, G.29
Olopade, O.I.30
Blum, J.L.31
Couch, F.J.32
Peterlongo, P.33
Manoukian, S.34
Barile, M.35
Radice, P.36
Szabo, C.I.37
Pereira, L.H.38
Greene, M.H.39
Rennert, G.40
Lejbkowicz, F.41
Barnett-Griness, O.42
Andrulis, I.L.43
Ozcelik, H.44
Ocgn45
Gerdes, A.M.46
Caligo, M.A.47
Laitman, Y.48
Kaufman, B.49
Milgrom, R.50
Friedman, E.51
Domchek, S.M.52
Nathanson, K.L.53
Osorio, A.54
Llort, G.55
Milne, R.L.56
Benitez, J.57
Hamann, U.58
Hogervorst, F.B.59
Manders, P.60
Ligtenberg, M.J.61
Van Den Ouweland, A.M.62
Peock, S.63
Cook, M.64
Platte, R.65
Evans, D.G.66
Eeles, R.67
Pichert, G.68
Chu, C.69
Eccles, D.70
Davidson, R.71
Douglas, F.72
Godwin, A.K.73
Barjhoux, L.74
Mazoyer, S.75
Sobol, H.76
Bourdon, V.77
Eisinger, F.78
Chompret, A.79
Capoulade, C.80
Bressac-de Paillerets, B.81
Lenoir, G.M.82
Gauthier-Villars, M.83
Houdayer, C.84
Lyonnet D.S.-85
Chenevix-Trench, G.86
Easton, D.F.87
more..
-
19
-
-
80052225995
-
Modification of BRCA1-Associated breast and ovarian cancer risk by BRCA1-Interacting genes
-
Epidemiological Study of BRCA1 and BRCA2 Mutation Carriers (EMBRACE
-
TR Rebbeck, N Mitra, SM Domchek, F Wan, TM Friebel, TV Tran, CF Singer, MK Tea, JL Blum, N Tung, OI Olopade, JN Weitzel, HT Lynch, CL Snyder, JE Garber, AC Antoniou, S Peock, DG Evans, J Paterson, MJ Kennedy, A Donaldson, H Dorkins, DF Easton, Epidemiological Study of BRCA1 and BRCA2 Mutation Carriers (EMBRACE), WS Rubinstein, MB Daly, C Isaacs, H Nevanlinna, FJ Couch, IL Andrulis, E Freidman, Y Laitman, PA Ganz, GE Tomlinson, SL Neuhausen, SA Narod, CM Phelan, R Greenberg and KL Nathanson: Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes. Cancer Res 71, 5792-5805 (2011).
-
(2011)
Cancer Res
, vol.71
, pp. 5792-5805
-
-
Rebbeck, T.R.1
Mitra, N.2
Domchek, S.M.3
Wan, F.4
Friebel, T.M.5
Tran, T.V.6
Singer, C.F.7
Tea, M.K.8
Blum, J.L.9
Tung, N.10
Olopade, O.I.11
Weitzel, J.N.12
Lynch, H.T.13
Snyder, C.L.14
Garber, J.E.15
Antoniou, A.C.16
Peock, S.17
Evans, D.G.18
Paterson, J.19
Kennedy, M.J.20
Donaldson, A.21
Dorkins, H.22
Easton, D.F.23
Rubinstein, W.S.24
Daly, M.B.25
Isaacs, C.26
Nevanlinna, H.27
Couch, F.J.28
Andrulis, I.L.29
Freidman, E.30
Laitman, Y.31
Ganz, P.A.32
Tomlinson, G.E.33
Neuhausen, S.L.34
Narod, S.A.35
Phelan, C.M.36
Greenberg, R.37
Nathanson, K.L.38
more..
-
20
-
-
50049112746
-
Molecular basis of the Li-Fraumeni syndrome: An update from the French LFS families
-
and French LFS working group
-
G Bougeard, R Sesboue, S Baert-Desurmont, S Vasseur, C Martin, J Tinat, L Brugieres, A Chompret, BB de Paillerets, D Stoppa-Lyonnet, C Bonaiti-Pellie, T Frebourg and French LFS working group: Molecular basis of the Li-Fraumeni syndrome: an update from the French LFS families. J Med Genet 45, 535-538 (2008).
-
(2008)
J Med Genet
, vol.45
, pp. 535-538
-
-
Bougeard, G.1
Sesboue, R.2
Baert-Desurmont, S.3
Vasseur, S.4
Martin, C.5
Tinat, J.6
Brugieres, L.7
Chompret, A.8
Baert-Desurmont, B.9
Stoppa-Lyonnet, D.10
Bonaiti-Pellie, C.11
Frebourg, T.12
-
21
-
-
73949160939
-
Beyond BRCA1 and BRCA2 wild-type breast and/or ovarian cancer families: Germline mutations in TP53 and PTEN
-
A Blanco, B Grana, L Fachal, M Santamarina, J Cameselle-Teijeiro, C Ruiz-Ponte, A Carracedo and A Vega: Beyond BRCA1 and BRCA2 wild-type breast and/or ovarian cancer families: germline mutations in TP53 and PTEN. Clin Genet 77, 193-196 (2010).
-
(2010)
Clin Genet
, vol.77
, pp. 193-196
-
-
Blanco, A.1
Grana, B.2
Fachal, L.3
Santamarina, M.4
Cameselle-Teijeiro, J.5
Ruiz-Ponte, C.6
Carracedo, A.7
Vega, A.8
-
22
-
-
84863783292
-
Familial breast cancer
-
F Lalloo and DG Evans: Familial breast cancer. Clin Genet 82, 105-114 (2012).
-
(2012)
Clin Genet
, vol.82
, pp. 105-114
-
-
Lalloo, F.1
Evans, D.G.2
-
23
-
-
84860605783
-
Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: A prospective cohort study
-
AK Win, JP Young, NM Lindor, KM Tucker, DJ Ahnen, GP Young, DD Buchanan, M Clendenning, GG Giles, I Winship, FA Macrae, J Goldblatt, MC Southey, J Arnold, SN Thibodeau, SR Gunawardena, B Bapat, JA Baron, G Casey, S Gallinger, L Le Marchand, PA Newcomb, RW Haile, JL Hopper and MA Jenkins: Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study. J Clin Oncol 30, 958-964 (2012).
-
(2012)
J Clin Oncol
, vol.30
, pp. 958-964
-
-
Win, A.K.1
Young, J.P.2
Lindor, N.M.3
Tucker, K.M.4
Ahnen, D.J.5
Young, G.P.6
Buchanan, D.D.7
Clendenning, M.8
Giles, G.G.9
Winship, I.10
Macrae, F.A.11
Goldblatt, J.12
Southey, M.C.13
Arnold, J.14
Thibodeau, S.N.15
Gunawardena, S.R.16
Bapat, B.17
Baron, J.A.18
Casey, G.19
Gallinger, S.20
Marchand, L.L.21
Newcomb, P.A.22
Haile, R.W.23
Hopper, J.L.24
Jenkins, M.A.25
more..
-
24
-
-
33846850422
-
Ten Genes for Inherited Breast Cancer
-
DOI 10.1016/j.ccr.2007.01.010, PII S1535610807000256
-
T Walsh and MC King: Ten genes for inherited breast cancer. Cancer Cell 11, 103-105 (2007). (Pubitemid 46209856)
-
(2007)
Cancer Cell
, vol.11
, Issue.2
, pp. 103-105
-
-
Walsh, T.1
King, M.-C.2
-
25
-
-
45949085378
-
Polygenes, risk prediction, and targeted prevention of breast cancer
-
DOI 10.1056/NEJMsa0708739
-
PD Pharoah, AC Antoniou, DF Easton and BA Ponder: Polygenes, risk prediction, and targeted prevention of breast cancer. N Engl J Med 358, 2796-2803 (2008). (Pubitemid 351930854)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.26
, pp. 2796-2803
-
-
Pharoah, P.D.P.1
Antoniou, A.C.2
Easton, D.F.3
Ponder, B.A.J.4
-
26
-
-
0033601346
-
Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome
-
DW Bell, JM Varley, TE Szydlo, DH Kang, DC Wahrer, KE Shannon, M Lubratovich, SJ Verselis, KJ Isselbacher, JF Fraumeni, JM Birch, FP Li, JE Garber and DA Haber: Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome. Science 286, 2528-2531 (1999).
-
(1999)
Science
, vol.286
, pp. 2528-2531
-
-
Bell, D.W.1
Varley, J.M.2
Szydlo, T.E.3
Kang, D.H.4
Wahrer, D.C.5
Shannon, K.E.6
Lubratovich, M.7
Verselis, S.J.8
Isselbacher, K.J.9
Fraumeni, J.F.10
Birch, J.M.11
Li, F.P.12
Garber, J.E.13
Haber, D.A.14
-
27
-
-
36448973875
-
CHK2 kinase: Cancer susceptibility and cancer therapy - Two sides of the same coin?
-
DOI 10.1038/nrc2251, PII NRC2251
-
L Antoni, N Sodha, I Collins and MD Garrett: CHK2 kinase: cancer susceptibility and cancer therapy-two sides of the same coin? Nat Rev Cancer 7, 925-936 (2007). (Pubitemid 350165855)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.12
, pp. 925-936
-
-
Antoni, L.1
Sodha, N.2
Collins, I.3
Garrett, M.D.4
-
28
-
-
3042582651
-
CHEK2*1100delC and susceptibility to breast cancer: A collaborative analysis involving 10, 860 breast cancer cases and 9, 065 controls from 10 studies
-
CHEK2 Breast Cancer Case-Control Consortium
-
CHEK2 Breast Cancer Case-Control Consortium, CHEK2*1100delC and susceptibility to breast cancer: a collaborative analysis involving 10, 860 breast cancer cases and 9, 065 controls from 10 studies. Am J Hum Genet 74, 1175-1182 (2004).
-
(2004)
Am J Hum Genet
, vol.74
, pp. 1175-1182
-
-
-
29
-
-
39149141409
-
CHEK2 1100delC genotyping for clinical assessment of breast cancer risk: Meta-analyses of 26,000 patient cases and 27,000 controls
-
DOI 10.1200/JCO.2007.12.5922
-
M Weischer, SE Bojesen, C Ellervik, A Tybjaerg-Hansen and BG Nordestgaard: CHEK2*1100delC genotyping for clinical assessment of breast cancer risk: meta-analyses of 26, 000 patient cases and 27, 000 controls. J Clin Oncol 26, 542-548 (2008). (Pubitemid 351264346)
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.4
, pp. 542-548
-
-
Weischer, M.1
Bojesen, S.E.2
Ellervik, C.3
Tybjaerg-Hansen, A.4
Nordestgaard, B.G.5
-
31
-
-
84856014217
-
CHEK2*1100delC homozygosity is associated with a high breast cancer risk in women
-
MA Adank, MA Jonker, I Kluijt, SE van Mil, RA Oldenburg, WJ Mooi, FB Hogervorst, AM van den Ouweland, JJ Gille, MK Schmidt, AW van der Vaart, H Meijers-Heijboer and Q Waisfisz: CHEK2*1100delC homozygosity is associated with a high breast cancer risk in women. J Med Genet 48, 860-863 (2011).
-
(2011)
J Med Genet
, vol.48
, pp. 860-863
-
-
Adank, M.A.1
Jonker, M.A.2
Kluijt, I.3
Van Mil, S.E.4
Oldenburg, R.A.5
Mooi, W.J.6
Hogervorst, F.B.7
Van Der Ouweland, A.M.8
Gille, J.J.9
Schmidt, M.K.10
Van Der Vaart, A.W.11
Meijers-Heijboer, H.12
Waisfisz, Q.13
-
32
-
-
33645084562
-
Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high risk of breast cancer
-
T Walsh, S Casadei, KH Coats, E Swisher, SM Stray, J Higgins, KC Roach, J Mandell, MK Lee, S Ciernikova, L Foretova, P Soucek and MC King: Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high risk of breast cancer. JAMA 295, 1379-1388 (2006).
-
(2006)
JAMA
, vol.295
, pp. 1379-1388
-
-
Walsh, T.1
Casadei, S.2
Coats, K.H.3
Swisher, E.4
Stray, S.M.5
Higgins, J.6
Roach, K.C.7
Mandell, J.8
Lee, M.K.9
Ciernikova, S.10
Foretova, L.11
Soucek, P.12
King, M.C.13
-
33
-
-
0030482567
-
Molecular genotyping shows that ataxia-telangiectasia heterozygotes are predisposed to breast cancer
-
DOI 10.1016/S0165-4608(96)00328-7, PII S0165460896003287
-
P Athma, R Rappaport and M Swift: Molecular genotyping shows that ataxia-telangiectasia heterozygotes are predisposed to breast cancer. Cancer Genet Cytogenet 92, 130-134 (1996). (Pubitemid 26427675)
-
(1996)
Cancer Genetics and Cytogenetics
, vol.92
, Issue.2
, pp. 130-134
-
-
Athma, P.1
Rappaport, R.2
Swift, M.3
-
34
-
-
70350088548
-
Mechanisms of doublestrand break repair in somatic mammalian cells
-
AJ Hartlerode and R Scully: Mechanisms of doublestrand break repair in somatic mammalian cells. Biochem J 423, 157-168 (2009).
-
(2009)
Biochem J
, vol.423
, pp. 157-168
-
-
Hartlerode, A.J.1
Scully, R.2
-
35
-
-
0025276912
-
Cancer predisposition of ataxia-telangiectasia heterozygotes
-
DOI 10.1016/0165-4608(90)90004-T
-
M Swift, CL Chase, D Morrell: Cancer predisposition of ataxia-telangiectasia heterozygotes. Cancer Genet Cytogenet 46 (1), 21-27 (1990). (Pubitemid 20164925)
-
(1990)
Cancer Genetics and Cytogenetics
, vol.46
, Issue.1
, pp. 21-27
-
-
Swift, M.1
Chase, C.L.2
Morrell, D.3
-
36
-
-
74849120035
-
ATM germline mutations in women with familial breast cancer and a relative with haematological malignancy
-
LL Paglia, A Lauge, J Weber, J Champ, E Cavaciuti, A Russo, JL Viovy and D Stoppa-Lyonnet: ATM germline mutations in women with familial breast cancer and a relative with haematological malignancy. Breast Cancer Res Treat 119, 443-452 (2010).
-
(2010)
Breast Cancer Res Treat
, vol.119
, pp. 443-452
-
-
Paglia, L.L.1
Lauge, A.2
Weber, J.3
Champ, J.4
Cavaciuti, E.5
Russo, A.6
Viovy, J.L.7
Stoppa-Lyonnet, D.8
-
37
-
-
33746491583
-
ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles
-
DOI 10.1038/ng1837, PII NG1837
-
A Renwick, D Thompson, S Seal, P Kelly, T Chagtai, M Ahmed, B North, H Jayatilake, R Barfoot, K Spanova, L McGuffog, DG Evans, D Eccles, Breast Cancer Susceptibility Collaboration (UK), DF Easton, MR Stratton and N Rahman: ATM mutations that cause ataxiatelangiectasia are breast cancer susceptibility alleles. Nat Genet 38, 873-875 (2006). (Pubitemid 44141653)
-
(2006)
Nature Genetics
, vol.38
, Issue.8
, pp. 873-875
-
-
Renwick, A.1
Thompson, D.2
Seal, S.3
Kelly, P.4
Chagtai, T.5
Ahmed, M.6
North, B.7
Jayatilake, H.8
Barfoot, R.9
Spanova, K.10
McGuffog, L.11
Evans, D.G.12
Eccles, D.13
Easton, D.F.14
Stratton, M.R.15
Rahman, N.16
-
38
-
-
37249013876
-
The spectrum of ATM missense variants and their contribution to contralateral breast cancer
-
DOI 10.1007/s10549-007-9543-6
-
A Broeks, LM Braaf, A Huseinovic, MK Schmidt, NS Russell, FE van Leeuwen, FB Hogervorst and LJ Van 't Veer: The spectrum of ATM missense variants and their contribution to contralateral breast cancer. Breast Cancer Res Treat 107, 243-248 (2008). (Pubitemid 350265692)
-
(2008)
Breast Cancer Research and Treatment
, vol.107
, Issue.2
, pp. 243-248
-
-
Broeks, A.1
Braaf, L.M.2
Huseinovic, A.3
Schmidt, M.K.4
Russell, N.S.5
Van Leeuwen, F.E.6
Hogervorst, F.B.L.7
Van 'T Veer, L.J.8
-
39
-
-
36949013395
-
ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks
-
DOI 10.1038/sj.onc.1210880, PII 1210880
-
MF Lavin: ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks. Oncogene 26, 7749-7758 (2007). (Pubitemid 350242462)
-
(2007)
Oncogene
, vol.26
, Issue.56
, pp. 7749-7758
-
-
Lavin, M.F.1
-
40
-
-
1542542679
-
Mutation screening of Mre11 complex genes: Indication of RAD50 involvement in breast and ovarian cancer susceptibility
-
K Heikkinen, SM Karppinen, Y Soini, M Makinen and R Winqvist: Mutation screening of Mre11 complex genes: indication of RAD50 involvement in breast and ovarian cancer susceptibility. J Med Genet 40, e131 (2003).
-
(2003)
J Med Genet
, vol.40
-
-
Heikkinen, K.1
Karppinen, S.M.2
Soini, Y.3
Makinen, M.4
Winqvist, R.5
-
41
-
-
33747884830
-
RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability
-
DOI 10.1093/carcin/bgi360, Special Issue on Chronic Pain
-
K Heikkinen, K Rapakko, SM Karppinen, H Erkko, S Knuutila, T Lundan, A Mannermaa, AL Borresen-Dale, A Borg, RB Barkardottir, J Petrini and R Winqvist: RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability. Carcinogenesis 27, 1593-1599 (2006). (Pubitemid 44288048)
-
(2006)
Carcinogenesis
, vol.27
, Issue.8
, pp. 1593-1599
-
-
Heikkinen, K.1
Rapakko, K.2
Karppinen, S.-M.3
Erkko, H.4
Knuutila, S.5
Lundan, T.6
Mannermaa, A.7
Borresen-Dale, A.-L.8
Borg, A.9
Barkardottir, R.B.10
Petrini, J.11
Winqvist, R.12
-
42
-
-
3242892589
-
Nijmegen breakage syndrome: Clinical manifestation of defective response to DNA double-strand breaks
-
DOI 10.1016/j.dnarep.2004.03.004, PII S1568786404000631
-
M Digweed and K Sperling: Nijmegen breakage syndrome: clinical manifestation of defective response to DNA double-strand breaks. DNA Repair (Amst) 3, 1207-1217 (2004). (Pubitemid 38997964)
-
(2004)
DNA Repair
, vol.3
, Issue.8-9
, pp. 1207-1217
-
-
Digweed, M.1
Sperling, K.2
-
43
-
-
38349052915
-
Nijmegen breakage syndrome mutations and risk of breast cancer
-
N Bogdanova, S Feshchenko, P Schurmann, R Waltes, B Wieland, P Hillemanns, YI Rogov, O Dammann, M Bremer, JH Karstens, C Sohn, R Varon and T Dork: Nijmegen Breakage Syndrome mutations and risk of breast cancer. Int J Cancer 122, 802-806 (2008).
-
(2008)
Int J Cancer
, vol.122
, pp. 802-806
-
-
Bogdanova, N.1
Feshchenko, S.2
Schurmann, P.3
Waltes, R.4
Wieland, B.5
Hillemanns, P.6
Rogov, Y.I.7
Dammann, O.8
Bremer, M.9
Karstens, J.H.10
Sohn, C.11
Varon, R.12
Dork, T.13
-
44
-
-
0038505600
-
Germline 657del5 mutation in the NBS1 gene in breast cancer patients
-
DOI 10.1002/ijc.11231
-
B Gorski, T Debniak, B Masojc, M Mierzejewski, K Medrek, C Cybulski, A Jakubowska, G Kurzawski, M Chosia, R Scott and J Lubinski: Germline 657del5 mutation in the NBS1 gene in breast cancer patients. Int J Cancer 106, 379-381 (2003). (Pubitemid 36870400)
-
(2003)
International Journal of Cancer
, vol.106
, Issue.3
, pp. 379-381
-
-
Gorski, B.1
Debniak, T.2
Masojc, B.3
Mierzejewski, M.4
Medrek, K.5
Cybulski, C.6
Jakubowska, A.7
Kurzawski, G.8
Chosia, M.9
Scott, R.10
Lubinski, J.11
-
45
-
-
18444362122
-
Biallelic inactivation of BRCA2 in Fanconi anemia
-
DOI 10.1126/science.1073834
-
N G Howlett, T Taniguchi, S Olson, B Cox, Q Waisfisz, C De Die-Smulders, N Persky, M Grompe, H Joenje, G Pals, H Ikeda, E A Fox and A D D'Andrea: Biallelic inactivation of BRCA2 in Fanconi anemia. Science 297, 606-609 (2002). (Pubitemid 34815345)
-
(2002)
Science
, vol.297
, Issue.5581
, pp. 606-609
-
-
Howlett, N.G.1
Taniguchi, T.2
Olson, S.3
Cox, B.4
Waisfisz, Q.5
De Die-Smulders, C.6
Persky, N.7
Grompe, M.8
Joenje, H.9
Pals, G.10
Ikeda, H.11
Fox, E.A.12
D'Andrea, A.D.13
-
46
-
-
72149119542
-
How the fanconi anemia pathway guards the genome
-
G L Moldovan and A D D'Andrea: How the fanconi anemia pathway guards the genome. Annu Rev Genet 43, 223-249 (2009).
-
(2009)
Annu Rev Genet
, vol.43
, pp. 223-249
-
-
Moldovan, G.L.1
D'andrea, A.D.2
-
47
-
-
34548759123
-
Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins
-
DOI 10.1038/nrg2159, PII NRG2159
-
W Wang: Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins. Nat Rev Genet 8, 735-748 (2007). (Pubitemid 47429206)
-
(2007)
Nature Reviews Genetics
, vol.8
, Issue.10
, pp. 735-748
-
-
Wang, W.1
-
48
-
-
0037441757
-
A 20-year perspective on the International Fanconi Anemia Registry (IFAR)
-
DOI 10.1182/blood-2002-07-2170
-
D I Kutler, B Singh, J Satagopan, S D Batish, M Berwick, P F Giampietro, H Hanenberg and A D Auerbach: A 20-year perspective on the International Fanconi Anemia Registry (IFAR). Blood 101, 1249-1256 (2003). (Pubitemid 36182492)
-
(2003)
Blood
, vol.101
, Issue.4
, pp. 1249-1256
-
-
Kutler, D.I.1
Singh, B.2
Satagopan, J.3
Batish, S.D.4
Berwick, M.5
Giampietro, P.F.6
Hanenberg, H.7
Auerbach, A.D.8
-
49
-
-
25144497571
-
The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia
-
DOI 10.1038/ng1624, PII NG1624
-
O Levran, C Attwooll, R T Henry, K L Milton, K Neveling, P Rio, S D Batish, R Kalb, E Velleuer, S Barral, J Ott, J Petrini, D Schindler, H Hanenberg and A D Auerbach: The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia. Nat Genet 37, 931-933 (2005). (Pubitemid 43086147)
-
(2005)
Nature Genetics
, vol.37
, Issue.9
, pp. 931-933
-
-
Levran, O.1
Attwooll, C.2
Henry, R.T.3
Milton, K.L.4
Neveling, K.5
Rio, P.6
Batish, S.D.7
Kalb, R.8
Velleuer, E.9
Barral, S.10
Ott, J.11
Petrini, J.12
Schindler, D.13
Hanenberg, H.14
Auerbach, A.D.15
-
50
-
-
1442281478
-
The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations
-
DOI 10.1073/pnas.0308717101
-
S Cantor, R Drapkin, F Zhang, Y Lin, J Han, S Pamidi and DM Livingston: The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations. Proc Natl Acad Sci U S A 101, 2357-2362 (2004). (Pubitemid 38269316)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.8
, pp. 2357-2362
-
-
Cantor, S.1
Drapkin, R.2
Zhang, F.3
Lin, Y.4
Han, J.5
Pamidi, S.6
Livingston, D.M.7
-
51
-
-
33750465216
-
Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles
-
DOI 10.1038/ng1902, PII NG1902
-
S Seal, D Thompson, A Renwick, A Elliott, P Kelly, R Barfoot, T Chagtai, H Jayatilake, M Ahmed, K Spanova, B North, L McGuffog, DG Evans, D Eccles, Breast Cancer Susceptibility Collaboration (UK), DF Easton, MR Stratton and N Rahman: Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles. Nat Genet 38, 1239-1241 (2006). (Pubitemid 44646283)
-
(2006)
Nature Genetics
, vol.38
, Issue.11
, pp. 1239-1241
-
-
Seal, S.1
Thompson, D.2
Renwick, A.3
Elliott, A.4
Kelly, P.5
Barfoot, R.6
Chagtai, T.7
Jayatilake, H.8
Ahmed, M.9
Spanova, K.10
North, B.11
McGuffog, L.12
Evans, D.G.13
Eccles, D.14
Easton, D.F.15
Stratton, M.R.16
Rahman, N.17
-
52
-
-
33846601829
-
Fanconi anemia is associated with a defect in the BRCA2 partner PALB2
-
DOI 10.1038/ng1942, PII NG1942
-
B Xia, JC Dorsman, N Ameziane, Y de Vries, MA Rooimans, Q Sheng, G Pals, A Errami, E Gluckman, J Llera, W Wang, D M Livingston, H Joenje and JP de Winter: Fanconi anemia is associated with a defect in the BRCA2 partner PALB2. Nat Genet 39, 159-161 (2007). (Pubitemid 46184344)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 159-161
-
-
Xia, B.1
Dorsman, J.C.2
Ameziane, N.3
De Vries, Y.4
Rooimans, M.A.5
Sheng, Q.6
Pals, G.7
Errami, A.8
Gluckman, E.9
Llera, J.10
Wang, W.11
Livingston, D.M.12
Joenje, H.13
De Winter, J.P.14
-
53
-
-
33846625493
-
PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene
-
DOI 10.1038/ng1959, PII NG1959
-
N Rahman, S Seal, D Thompson, P Kelly, A Renwick, A Elliott, S Reid, K Spanova, R Barfoot, T Chagtai, H Jayatilake, L McGuffog, S Hanks, DG Evans, D Eccles, Breast Cancer Susceptibility Collaboration (UK), DF Easton and MR Stratton: PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene. Nat Genet 39, 165-167 (2007). (Pubitemid 46184346)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 165-167
-
-
Rahman, N.1
Seal, S.2
Thompson, D.3
Kelly, P.4
Renwick, A.5
Elliott, A.6
Reid, S.7
Spanova, K.8
Barfoot, R.9
Chagtai, T.10
Jayatilake, H.11
McGuffog, L.12
Hanks, S.13
Evans, D.G.14
Eccles, D.15
Easton, D.F.16
Stratton, M.R.17
-
54
-
-
62549115236
-
PALB2 links BRCA1 and BRCA2 in the DNA-damage response
-
F Zhang, J Ma, J Wu, L Ye, H Cai, B Xia and X Yu: PALB2 links BRCA1 and BRCA2 in the DNA-damage response. Curr Biol 19, 524-529 (2009).
-
(2009)
Curr Biol
, vol.19
, pp. 524-529
-
-
Zhang, F.1
Ma, J.2
Wu, J.3
Ye, L.4
Cai, H.5
Xia, B.6
Yu, X.7
-
55
-
-
51649092869
-
Penetrance analysis of the PALB2 c.1592delT founder mutation
-
H Erkko, JG Dowty, J Nikkila, K Syrjakoski, A Mannermaa, K Pylkas, MC Southey, K Holli, A Kallioniemi, A Jukkola-Vuorinen, V Kataja, VM Kosma, B Xia, DM Livingston, R Winqvist and JL Hopper: Penetrance analysis of the PALB2 c.1592delT founder mutation. Clin Cancer Res 14, 4667-4671 (2008).
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4667-4671
-
-
Erkko, H.1
Dowty, J.G.2
Nikkila, J.3
Syrjakoski, K.4
Mannermaa, A.5
Pylkas, K.6
Southey, M.C.7
Holli, K.8
Kallioniemi, A.9
Jukkola-Vuorinen, A.10
Kataja, V.11
Kosma, V.M.12
Xia, B.13
Livingston, D.M.14
Winqvist, R.15
Hopper, J.L.16
-
56
-
-
64849092309
-
Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene
-
S Jones, RH Hruban, M Kamiyama, M Borges, X Zhang, DW Parsons, JC Lin, E Palmisano, K Brune, EM Jaffee, CA Iacobuzio-Donahue, A Maitra, G Parmigiani, SE Kern, VE Velculescu, KW Kinzler, B Vogelstein, JR Eshleman, M Goggins and AP Klein: Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene. Science 324, 217 (2009).
-
(2009)
Science
, vol.324
, Issue.217
-
-
Jones, S.1
Hruban, R.H.2
Kamiyama, M.3
Borges, M.4
Zhang, X.5
Parsons, D.W.6
Lin, J.C.7
Palmisano, E.8
Brune, K.9
Jaffee, E.M.10
Iacobuzio-Donahue, C.A.11
Maitra, A.12
Parmigiani, G.13
Kern, S.E.14
Velculescu, V.E.15
Kinzler, K.W.16
Vogelstein, B.17
Eshleman, J.R.18
Goggins, M.19
Klein, A.P.20
more..
-
57
-
-
79251632658
-
SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype
-
C Stoepker, K Hain, B Schuster, Y Hilhorst-Hofstee, MA Rooimans, J Steltenpool, AB Oostra, K Eirich, ET Korthof, AW Nieuwint, NG Jaspers, T Bettecken, H Joenje, D Schindler, J Rouse and JP de Winter: SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype. Nat Genet 43, 138-141 (2011).
-
(2011)
Nat Genet
, vol.43
, pp. 138-141
-
-
Stoepker, C.1
Hain, K.2
Schuster, B.3
Hilhorst-Hofstee, Y.4
Rooimans, M.A.5
Steltenpool, J.6
Oostra, A.B.7
Eirich, K.8
Korthof, E.T.9
Nieuwint, A.W.10
Jaspers, N.G.11
Bettecken, T.12
Joenje, H.13
Schindler, D.14
Rouse, J.15
Winter, J.P.D.16
-
58
-
-
84979919402
-
Analysis of the novel fanconi anemia gene SLX4/FANCP in familial breast cancer cases
-
JL Bakker, SE van Mil, G Crossan, N Sabbaghian, K De Leeneer, B Poppe, M Adank, H Gille, H Verheul, H Meijers-Heijboer, JP de Winter, K Claes, M Tischkowitz and Q Waisfisz: Analysis of the Novel Fanconi Anemia Gene SLX4/FANCP in Familial Breast Cancer Cases. Hum Mutat (2012).
-
(2012)
Hum Mutat
-
-
Bakker, J.L.1
Van Mil, S.E.2
Crossan, G.3
Sabbaghian, N.4
De Leeneer, K.5
Poppe, B.6
Adank, M.7
Gille, H.8
Verheul, H.9
Meijers-Heijboer, H.10
Winter, J.P.D.11
Claes, K.12
Tischkowitz, M.13
Waisfisz, Q.14
-
59
-
-
84894601872
-
M de la Hoya Low prevalence of SLX4 loss-of-function mutations in non-BRCA1/2 breast and/or ovarian cancer families
-
GR de Garibay, A Díaz, B Gaviña, A Romero, P Garre, A Vega, A Blanco, A Tosar, O Díez, P Pérez-Segura, E Díaz-Rubio, T Caldés, M de la Hoya Low prevalence of SLX4 loss-of-function mutations in non-BRCA1/2 breast and/or ovarian cancer families. Eur J Hum Genet (2012).
-
(2012)
Eur J Hum Genet
-
-
Garibay, G.R.D.1
Díaz, A.2
Gaviña, B.3
Romero, A.4
Garre, P.5
Vega, A.6
Blanco, A.7
Tosar, A.8
Díez, O.9
Pérez-Segura, P.10
Díaz-Rubio, E.11
Caldés, T.12
-
60
-
-
84866932831
-
Exome sequencing identifies rare deleterious mutations in DNA repair genes FANCC and BLM as potential breast cancer susceptibility alleles
-
ER Thompson, MA Doyle, GL Ryland, SM Rowley, DY Choong, RW Tothill, H Thorne, kConFab, DR Barnes, J Li, J Ellul, GK Philip, YC Antill, PA James, AH Trainer, G Mitchell and IG Campbell: Exome Sequencing Identifies Rare Deleterious Mutations in DNA Repair Genes FANCC and BLM as Potential Breast Cancer Susceptibility Alleles. PLoS Genet 8, e1002894 (2012).
-
(2012)
PLoS Genet
, vol.8
-
-
Thompson, E.R.1
Doyle, M.A.2
Ryland, G.L.3
Rowley, S.M.4
Choong, D.Y.5
Tothill, R.W.6
Thorne, H.7
Kconfab8
Barnes, D.R.9
Li, J.10
Ellul, J.11
Philip, G.K.12
Antill, Y.C.13
James, P.A.14
Trainer, A.H.15
Mitchell, G.16
Campbell, I.G.17
-
61
-
-
13944268723
-
The RAD51 gene family, genetic instability and cancer
-
DOI 10.1016/j.canlet.2004.08.018
-
J Thacker: The RAD51 gene family, genetic instability and cancer. Cancer Lett 219, 125-135 (2005). (Pubitemid 40269475)
-
(2005)
Cancer Letters
, vol.219
, Issue.2
, pp. 125-135
-
-
Thacker, J.1
-
62
-
-
2242443513
-
Insights into DNA recombination from the structure of a RAD51-BRCA2 complex
-
DOI 10.1038/nature01230
-
L Pellegrini, DS Yu, T Lo, S Anand, M Lee, TL Blundell and AR Venkitaraman: Insights into DNA recombination from the structure of a RAD51-BRCA2 complex. Nature 420, 287-293 (2002). (Pubitemid 35398178)
-
(2002)
Nature
, vol.420
, Issue.6913
, pp. 287-293
-
-
Pellegrini, L.1
Yu, D.S.2
Lo, T.3
Anand, S.4
Lee, M.5
Blundell, T.L.6
Venkitaraman, A.R.7
-
63
-
-
77951747926
-
Mutation of the RAD51C gene in a Fanconi anemia-like disorder
-
F Vaz, H Hanenberg, B Schuster, K Barker, C Wiek, V Erven, K Neveling, D Endt, I Kesterton, F Autore, F Fraternali, M Freund, L Hartmann, D Grimwade, R G Roberts, H Schaal, S Mohammed, N Rahman, D Schindler and C G Mathew: Mutation of the RAD51C gene in a Fanconi anemia-like disorder. Nat Genet 42, 406-409 (2010).
-
(2010)
Nat Genet
, vol.42
, pp. 406-409
-
-
Vaz, F.1
Hanenberg, H.2
Schuster, B.3
Barker, K.4
Wiek, C.5
Erven, V.6
Neveling, K.7
Endt, D.8
Kesterton, I.9
Autore, F.10
Fraternali, F.11
Freund, M.12
Hartmann, L.13
Grimwade, D.14
Roberts, R.G.15
Schaal, H.16
Mohammed, S.17
Rahman, N.18
Schindler, D.19
Mathew, C.G.20
more..
-
64
-
-
77951720395
-
Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene
-
A Meindl, H Hellebrand, C Wiek, V Erven, B Wappenschmidt, D Niederacher, M Freund, P Lichtner, L Hartmann, H Schaal, J Ramser, E Honisch, C Kubisch, H E Wichmann, K Kast, H Deissler, C Engel, B Muller-Myhsok, K Neveling, M Kiechle, C G Mathew, D Schindler, R K Schmutzler and H Hanenberg: Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. Nat Genet 42, 410-414 (2010).
-
(2010)
Nat Genet
, vol.42
, pp. 410-414
-
-
Meindl, A.1
Hellebrand, H.2
Wiek, C.3
Erven, V.4
Wappenschmidt, B.5
Niederacher, D.6
Freund, M.7
Lichtner, P.8
Hartmann, L.9
Schaal, H.10
Ramser, J.11
Honisch, E.12
Kubisch, C.13
Wichmann, H.E.14
Kast, K.15
Deissler, H.16
Engel, C.17
Myhsok B.M.-18
Neveling, K.19
Kiechle, M.20
Mathew, C.G.21
Schindler, D.22
Schmutzler, R.K.23
Hanenberg, H.24
more..
-
65
-
-
84863532805
-
Predominance of pathogenic missense variants in the RAD51C gene occurring in breast and ovarian cancer families
-
A Osorio, D Endt, F Fernández, K Eirich, M de la Hoya, R Schmutzler, T Caldés, A Meindl, D Schindler, J Benitez: Predominance of pathogenic missense variants in the RAD51C gene occurring in breast and ovarian cancer families. Hum Mol Genet 21(13):2889-2898 (2012).
-
(2012)
Hum Mol Genet
, vol.21
, Issue.13
, pp. 2889-2898
-
-
Osorio, A.1
Endt, D.2
Fernández, F.3
Eirich, K.4
De La Hoya, M.5
Schmutzler, R.6
Caldés, T.7
Meindl, A.8
Schindler, D.9
Benitez, J.10
-
66
-
-
80052264429
-
Germline mutations in RAD51D confer susceptibility to ovarian cancer
-
Breast Cancer Susceptibility Collaboration (UK
-
C Loveday, C Turnbull, E Ramsay, D Hughes, E Ruark, JR Frankum, G Bowden, B Kalmyrzaev, M Warren-Perry, K Snape, JW Adlard, J Barwell, J Berg, AF Brady, C Brewer, G Brice, C Chapman, J Cook, R Davidson, A Donaldson, F Douglas, L Greenhalgh, A Henderson, L Izatt, A Kumar, F Lalloo, Z Miedzybrodzka, PJ Morrison, J Paterson, M Porteous, MT Rogers, S Shanley, L Walker, Breast Cancer Susceptibility Collaboration (UK), D Eccles, DG Evans, A Renwick, S Seal, CJ Lord, A Ashworth, JS Reis-Filho, AC Antoniou and N Rahman: Germline mutations in RAD51D confer susceptibility to ovarian cancer. Nat Genet 43, 879-882 (2011).
-
(2011)
Nat Genet
, vol.43
, pp. 879-882
-
-
Loveday, C.1
Turnbull, C.2
Ramsay, E.3
Hughes, D.4
Ruark, E.5
Frankum, J.R.6
Bowden, G.7
Kalmyrzaev, B.8
Warren-Perry, M.9
Snape, K.10
Adlard, J.W.11
Barwell, J.12
Berg, J.13
Brady, A.F.14
Brewer, C.15
Brice, G.16
Chapman, C.17
Cook, J.18
Davidson, R.19
Donaldson, A.20
Douglas, F.21
Greenhalgh, L.22
Henderson, A.23
Izatt, L.24
Kumar, A.25
Lalloo, F.26
Miedzybrodzka, Z.27
Morrison, P.J.28
Paterson, J.29
Porteous, M.30
Rogers, M.T.31
Shanley, S.32
Walker, L.33
Eccles, D.34
Evans, D.G.35
Renwick, A.36
Seal, S.37
Lord, C.J.38
Ashworth, A.39
Filho J.S.R.-40
Antoniou, A.C.41
Rahman, N.42
more..
-
67
-
-
0032061317
-
XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages
-
N Liu, JE Lamerdin, RS Tebbs, D Schild, JD Tucker, MR Shen, KW Brookman, MJ Siciliano, CA Walter, W Fan, LS Narayana, ZQ Zhou, AW Adamson, KJ Sorensen, DJ Chen, NJ Jones and LH Thompson: XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages. Mol Cell 1, 783-793 (1998). (Pubitemid 128379063)
-
(1998)
Molecular Cell
, vol.1
, Issue.6
, pp. 783-793
-
-
Liu, N.1
Lamerdin, J.E.2
Tebbs, R.S.3
Schild, D.4
Tucker, J.D.5
Shen, M.R.6
Brookman, K.W.7
Siciliano, M.J.8
Walter, C.A.9
Fan, W.10
Narayana, L.S.11
Zhou, Z.-Q.12
Adamson, A.W.13
Sorensen, K.J.14
Chen, D.J.15
Jones, N.J.16
Thompson, L.H.17
-
68
-
-
33645744903
-
Polymorphisms in DNA double-strand break repair genes and risk of breast cancer: Two population-based studies in USA and Poland, and metaanalyses
-
M Garcia-Closas, KM Egan, PA Newcomb, LA Brinton, L Titus-Ernstoff, S Chanock, R Welch, J Lissowska, B Peplonska, N Szeszenia-Dabrowska, W Zatonski, A Bardin-Mikolajczak and JP Struewing: Polymorphisms in DNA double-strand break repair genes and risk of breast cancer: two population-based studies in USA and Poland, and metaanalyses. Hum Genet 119, 376-388 (2006).
-
(2006)
Hum Genet
, vol.119
, pp. 376-388
-
-
Garcia-Closas, M.1
Egan, K.M.2
Newcomb, P.A.3
Brinton, L.A.4
Titus-Ernstoff, L.5
Chanock, S.6
Welch, R.7
Lissowska, J.8
Peplonska, B.9
Szeszenia-Dabrowska, N.10
Zatonski, W.11
Bardin-Mikolajczak, A.12
Struewing, J.P.13
-
69
-
-
27144475439
-
Polymorphisms in DNA repair genes and epithelial ovarian cancer risk
-
DOI 10.1002/ijc.21047
-
A Auranen, H Song, C Waterfall, RA Dicioccio, B Kuschel, SK Kjaer, E Hogdall, C Hogdall, J Stratton, AS Whittemore, DF Easton, BA Ponder, KL Novik, AM Dunning, S Gayther and PD Pharoah: Polymorphisms in DNA repair genes and epithelial ovarian cancer risk. Int J Cancer 117, 611-618 (2005). (Pubitemid 41504549)
-
(2005)
International Journal of Cancer
, vol.117
, Issue.4
, pp. 611-618
-
-
Auranen, A.1
Song, H.2
Waterfall, C.3
DiCioccio, R.A.4
Kuschel, B.5
Kjaer, S.K.6
Hogdall, E.7
Hogdall, C.8
Stratton, J.9
Whittemore, A.S.10
Easton, D.F.11
Ponder, B.A.J.12
Novik, K.L.13
Dunning, A.M.14
Gayther, S.15
Pharoah, P.D.P.16
-
70
-
-
0034667360
-
A variant within the DNA repair gene XRCC3 is associated with the development of melanoma skin cancer
-
SL Winsey, NA Haldar, HP Marsh, M Bunce, SE Marshall, AL Harris, F Wojnarowska and KI Welsh: A variant within the DNA repair gene XRCC3 is associated with the development of melanoma skin cancer. Cancer Res 60, 5612-5616 (2000).
-
(2000)
Cancer Res
, vol.60
, pp. 5612-5616
-
-
Winsey, S.L.1
Haldar, N.A.2
Marsh, H.P.3
Bunce, M.4
Marshall, S.E.5
Harris, A.L.6
Wojnarowska, F.7
Welsh, K.I.8
-
71
-
-
20144383285
-
Radiation response genotype and risk of differentiated thyroid cancer: A case-control analysis
-
DOI 10.1097/01.MLG.0000163765.88158.86
-
EM Sturgis, C Zhao, R Zheng and Q Wei: Radiation response genotype and risk of differentiated thyroid cancer: a case-control analysis. Laryngoscope 115, 938-945 (2005). (Pubitemid 40776979)
-
(2005)
Laryngoscope
, vol.115
, Issue.6
, pp. 938-945
-
-
Sturgis, E.M.1
Zhao, C.2
Zheng, R.3
Wei, Q.4
-
72
-
-
79960398913
-
Combined effect of polymorphisms in Rad51 and Xrcc3 on breast cancer risk and chromosomal radiosensitivity
-
A Vral, P Willems, K Claes, B Poppe, G Perletti and H Thierens: Combined effect of polymorphisms in Rad51 and Xrcc3 on breast cancer risk and chromosomal radiosensitivity. Mol Med Report 4, 901-912 (2011).
-
(2011)
Mol Med Report
, vol.4
, pp. 901-912
-
-
Vral, A.1
Willems, P.2
Claes, K.3
Poppe, B.4
Perletti, G.5
Thierens, H.6
-
73
-
-
84859484153
-
Exome sequencing reveals a novel Fanconi group defined by XRCC2 mutation
-
HE Shamseldin, M Elfaki and FS Alkuraya: Exome sequencing reveals a novel Fanconi group defined by XRCC2 mutation. J Med Genet 49, 184-186 (2012).
-
(2012)
J Med Genet
, vol.49
, pp. 184-186
-
-
Shamseldin, H.E.1
Elfaki, M.2
Alkuraya, F.S.3
-
74
-
-
79151476661
-
RAD51 135G/C polymorphism and breast cancer risk: A meta-analysis from 21 studies
-
LB Gao, XM Pan, LJ Li, WB Liang, Y Zhu, LS Zhang, YG Wei, M Tang and L Zhang: RAD51 135G/C polymorphism and breast cancer risk: a meta-analysis from 21 studies. Breast Cancer Res Treat 125, 827-835 (2011).
-
(2011)
Breast Cancer Res Treat
, vol.125
, pp. 827-835
-
-
Gao, L.B.1
Pan, X.M.2
Li, L.J.3
Liang, W.B.4
Zhu, Y.5
Zhang, L.S.6
Wei, Y.G.7
Tang, M.8
Zhang, L.9
-
75
-
-
84859479737
-
Rare mutations in XRCC2 increase the risk of breast cancer
-
Breast Cancer Family Registry, Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer
-
DJ Park, F Lesueur, T Nguyen-Dumont, M Pertesi, F Odefrey, F Hammet, SL Neuhausen, EM John, IL Andrulis, MB Terry, M Daly, S Buys, F Le Calvez-Kelm, A Lonie, BJ Pope, H Tsimiklis, C Voegele, FM Hilbers, N Hoogerbrugge, A Barroso, A Osorio, Breast Cancer Family Registry, Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer, GG Giles, P Devilee, J Benitez, JL Hopper, SV Tavtigian, DE Goldgar and MC Southey: Rare mutations in XRCC2 increase the risk of breast cancer. Am J Hum Genet 90, 734-739 (2012).
-
(2012)
Am J Hum Genet
, vol.90
, pp. 734-739
-
-
Park, D.J.1
Lesueur, F.2
Nguyen-Dumont, T.3
Pertesi, M.4
Odefrey, F.5
Hammet, F.6
Neuhausen, S.L.7
John, E.M.8
Andrulis, I.L.9
Terry, M.B.10
Daly, M.11
Buys, S.12
Calvez-Kelm, F.L.13
Lonie, A.14
Pope, B.J.15
Tsimiklis, H.16
Voegele, C.17
Hilbers, F.M.18
Hoogerbrugge, N.19
Barroso, A.20
Osorio, A.21
Giles, G.G.22
Devilee, P.23
Benitez, J.24
Hopper, J.L.25
Tavtigian, S.V.26
Goldgar, D.E.27
Southey, M.C.28
more..
-
76
-
-
67349146516
-
Polymorphism of XRCC1 (at codon 399) and susceptibility to breast cancer, a meta-analysis of the literatures
-
M Saadat and M Ansari-Lari: Polymorphism of XRCC1 (at codon 399) and susceptibility to breast cancer, a meta-analysis of the literatures. Breast Cancer Res Treat 115, 137-144 (2009).
-
(2009)
Breast Cancer Res Treat
, vol.115
, pp. 137-144
-
-
Saadat, M.1
Ansari-Lari, M.2
-
77
-
-
2542499623
-
Clinical features of Bloom syndrome and function of the causative gene, BLM helicase
-
DOI 10.1586/14737159.4.3.393
-
H Kaneko and N Kondo: Clinical features of Bloom syndrome and function of the causative gene, BLM helicase. Expert Rev Mol Diagn 4, 393-401 (2004). (Pubitemid 38684714)
-
(2004)
Expert Review of Molecular Diagnostics
, vol.4
, Issue.3
, pp. 393-401
-
-
Kaneko, H.1
Kondo, N.2
-
78
-
-
84859884724
-
High prevalence and breast cancer predisposing role of the BLM c.1642 C>T (Q548X) mutation in Russia
-
AP Sokolenko, AG Iyevleva, EV Preobrazhenskaya, NV Mitiushkina, SN Abysheva, EN Suspitsin, ES Kuligina, TV Gorodnova, W Pfeifer, AV Togo, EA Turkevich, AO Ivantsov, DV Voskresenskiy, GD Dolmatov, EM Bit-Sava, DE Matsko, V F Semiglazov, I Fichtner, AA Larionov, SG Kuznetsov, AC Antoniou and EN Imyanitov: High prevalence and breast cancer predisposing role of the BLM c.1642 C>T (Q548X) mutation in Russia. Int J Cancer 130, 2867-2873 (2012).
-
(2012)
Int J Cancer
, vol.130
, pp. 2867-2873
-
-
Sokolenko, A.P.1
Iyevleva, A.G.2
Preobrazhenskaya, E.V.3
Mitiushkina, N.V.4
Abysheva, S.N.5
Suspitsin, E.N.6
Kuligina, E.S.7
Gorodnova, T.V.8
Pfeifer, W.9
Togo, A.V.10
Turkevich, E.A.11
Ivantsov, A.O.12
Voskresenskiy, D.V.13
Dolmatov, G.D.14
Bit-Sava, E.M.15
Matsko, D.E.16
Semiglazov, V.F.17
Fichtner, I.18
Larionov, A.A.19
Kuznetsov, S.G.20
Antoniou, A.C.21
Imyanitov, E.N.22
more..
-
79
-
-
18544386262
-
BLM heterozygosity and the risk of colorectal cancer
-
SB Gruber, NA Ellis, KK Scott, R Almog, P Kolachana, JD Bonner, T Kirchhoff, LP Tomsho, K Nafa, H Pierce, M Low, J Satagopan, H Rennert, H Huang, JK Greenson, J Groden, B Rapaport, J Shia, S Johnson, PK Gregersen, CC Harris, J Boyd, G Rennert and K Offit: BLM heterozygosity and the risk of colorectal cancer. Science 297, 2013 (2002).
-
(2002)
Science
, vol.297
, pp. 2013
-
-
Gruber, S.B.1
Ellis, N.A.2
Scott, K.K.3
Almog, R.4
Kolachana, P.5
Bonner, J.D.6
Kirchhoff, T.7
Tomsho, L.P.8
Nafa, K.9
Pierce, H.10
Low, M.11
Satagopan, J.12
Rennert, H.13
Huang, H.14
Greenson, J.K.15
Groden, J.16
Rapaport, B.17
Shia, J.18
Johnson, S.19
Gregersen, P.K.20
Harris, C.C.21
Boyd, J.22
Rennert, G.23
Offit, K.24
more..
-
80
-
-
0344953576
-
Ash mutation and cancer risk
-
SP Cleary, W Zhang, N Di Nicola, M Aronson, J Aube, A Steinman, R Haddad, M Redston, S Gallinger, SA Narod and R Gryfe: Heterozygosity for the BLM(Ash) mutation and cancer risk. Cancer Res 63, 1769-1771 (2003). (Pubitemid 36460835)
-
(2003)
Cancer Research
, vol.63
, Issue.8
, pp. 1769-1771
-
-
Cleary, S.P.1
Zhang, W.2
Di Nicola, N.3
Aronson, M.4
Aube, J.5
Steinman, A.6
Haddad, R.7
Redston, M.8
Gallinger, S.9
Narod, S.A.10
Gryfe, R.11
-
81
-
-
34249946686
-
Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response
-
DOI 10.1126/science.1139476
-
B Wang, S Matsuoka, BA Ballif, D Zhang, A Smogorzewska, SP Gygi and SJ Elledge: Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. Science 316, 1194-1198 (2007). (Pubitemid 46877482)
-
(2007)
Science
, vol.316
, Issue.5828
, pp. 1194-1198
-
-
Wang, B.1
Matsuoka, S.2
Ballif, B.A.3
Zhang, D.4
Smogorzewska, A.5
Gygi, S.P.6
Elledge, S.J.7
-
82
-
-
63049138322
-
NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control
-
B Wang, K Hurov, K Hofmann and SJ Elledge: NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control. Genes Dev 23, 729-739 (2009).
-
(2009)
Genes Dev
, vol.23
, pp. 729-739
-
-
Wang, B.1
Hurov, K.2
Hofmann, K.3
Elledge, S.J.4
-
83
-
-
63049083118
-
MERIT40 facilitates BRCA1 localization and DNA damage repair
-
L Feng, J Huang and J Chen: MERIT40 facilitates BRCA1 localization and DNA damage repair. Genes Dev 23, 719-728 (2009).
-
(2009)
Genes Dev
, vol.23
, pp. 719-728
-
-
Feng, L.1
Huang, J.2
Chen, J.3
-
84
-
-
58149268081
-
Evaluation of the BRCA1 interacting genes RAP80 and CCDC98 in familial breast cancer susceptibility
-
A Osorio, A Barroso, MJ Garcia, B Martinez-Delgado, M Urioste and J Benitez: Evaluation of the BRCA1 interacting genes RAP80 and CCDC98 in familial breast cancer susceptibility. Breast Cancer Res Treat 113, 371-376 (2009).
-
(2009)
Breast Cancer Res Treat
, vol.113
, pp. 371-376
-
-
Osorio, A.1
Barroso, A.2
Garcia, M.J.3
Martinez-Delgado, B.4
Urioste, M.5
Benitez, J.6
-
85
-
-
67349155596
-
Familial breast cancer screening reveals an alteration in the RAP80 UIM domain that impairs DNA damage response function
-
J Nikkila, KA Coleman, D Morrissey, K Pylkas, H Erkko, TE Messick, SM Karppinen, A Amelina, R Winqvist and RA Greenberg: Familial breast cancer screening reveals an alteration in the RAP80 UIM domain that impairs DNA damage response function. Oncogene 28, 1843-1852 (2009).
-
(2009)
Oncogene
, vol.28
, pp. 1843-1852
-
-
Nikkila, J.1
Coleman, K.A.2
Morrissey, D.3
Pylkas, K.4
Erkko, H.5
Messick, T.E.6
Karppinen, S.M.7
Amelina, A.8
Winqvist, R.9
Greenberg, R.A.10
-
86
-
-
74849102973
-
Mutation screening of the MERIT40 gene encoding a novel BRCA1 and RAP80 interacting protein in breast cancer families
-
S Solyom, J Patterson-Fortin, K Pylkas, RA Greenberg and R Winqvist: Mutation screening of the MERIT40 gene encoding a novel BRCA1 and RAP80 interacting protein in breast cancer families. Breast Cancer Res Treat 120, 165-168 (2010).
-
(2010)
Breast Cancer Res Treat
, vol.120
, pp. 165-168
-
-
Solyom, S.1
Patterson-Fortin, J.2
Pylkas, K.3
Greenberg, R.A.4
Winqvist, R.5
-
87
-
-
36749084931
-
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
-
DOI 10.1126/science.1150034
-
NK Kolas, JR Chapman, S Nakada, J Ylanko, R Chahwan, FD Sweeney, S Panier, M Mendez, J Wildenhain, TM Thomson, L Pelletier, SP Jackson and D Durocher: Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science 318, 1637-1640 (2007). (Pubitemid 350233664)
-
(2007)
Science
, vol.318
, Issue.5856
, pp. 1637-1640
-
-
Kolas, N.K.1
Chapman, J.R.2
Nakada, S.3
Ylanko, J.4
Chahwan, R.5
Sweeney, F.D.6
Panier, S.7
Mendez, M.8
Wildenhain, J.9
Thomson, T.M.10
Pelletier, L.11
Jackson, S.P.12
Durocher, D.13
-
88
-
-
79960556792
-
Mutation screening of the RNF8, UBC13 and MMS2 genes in Northern Finnish breast cancer families
-
M Vuorela, K Pylkas and R Winqvist: Mutation screening of the RNF8, UBC13 and MMS2 genes in Northern Finnish breast cancer families. BMC Med Genet 12, 98 (2011).
-
(2011)
BMC Med Genet
, vol.12
, Issue.98
-
-
Vuorela, M.1
Pylkas, K.2
Winqvist, R.3
-
89
-
-
77952318450
-
Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer
-
L Li, MJ Halaby, A Hakem, R Cardoso, S El Ghamrasni, S Harding, N Chan, R Bristow, O Sanchez, D Durocher and R Hakem: Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer. J Exp Med 207, 983-997 (2010).
-
(2010)
J Exp Med
, vol.207
, pp. 983-997
-
-
Li, L.1
Halaby, M.J.2
Hakem, A.3
Cardoso, R.4
Ghamrasni, S.E.5
Harding, S.6
Chan, N.7
Bristow, R.8
Sanchez, O.9
Durocher, D.10
Hakem, R.11
-
90
-
-
59049103900
-
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
-
GS Stewart, S Panier, K Townsend, AK Al-Hakim, NK Kolas, ES Miller, S Nakada, J Ylanko, S Olivarius, M Mendez, C Oldreive, J Wildenhain, A Tagliaferro, L Pelletier, N Taubenheim, A Durandy, PJ Byrd, T Stankovic, AM Taylor and D Durocher: The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell 136, 420-434 (2009).
-
(2009)
Cell
, vol.136
, pp. 420-434
-
-
Stewart, G.S.1
Panier, S.2
Townsend, K.3
Al-Hakim, A.K.4
Kolas, N.K.5
Miller, E.S.6
Nakada, S.7
Ylanko, J.8
Olivarius, S.9
Mendez, M.10
Oldreive, C.11
Wildenhain, J.12
Tagliaferro, A.13
Pelletier, L.14
Taubenheim, N.15
Durandy, A.16
Byrd, P.J.17
Stankovic, T.18
Taylor, A.M.19
Durocher, D.20
more..
-
91
-
-
84862776961
-
Genome-wide association analysis identifies three new breast cancer susceptibility loci
-
Netherlands Collaborative Group on Hereditary Breast and Ovarian Cancer (HEBON), Familial Breast Cancer Study (FBCS), Gene Environment Interaction of Breast Cancer in Germany (GENICA) Network
-
M Ghoussaini, O Fletcher, K Michailidou, C Turnbull, MK Schmidt, E Dicks, J Dennis, Q Wang, MK Humphreys, C Luccarini, C Baynes, D Conroy, M Maranian, S Ahmed, K Driver, N Johnson, N Orr, I dos Santos Silva, Q Waisfisz, H Meijers-Heijboer, AG Uitterlinden, F Rivadeneira, Netherlands Collaborative Group on Hereditary Breast and Ovarian Cancer (HEBON), P Hall, K Czene, A Irwanto, J Liu, H Nevanlinna, K Aittomaki, C Blomqvist, A Meindl, RK Schmutzler, B Muller-Myhsok, P Lichtner, J Chang-Claude, R Hein, S Nickels, D Flesch-Janys, H Tsimiklis, E Makalic, D Schmidt, M Bui, JL Hopper, C Apicella, DJ Park, M Southey, DJ Hunter, SJ Chanock, A Broeks, S Verhoef, FB Hogervorst, PA Fasching, MP Lux, MW Beckmann, AB Ekici, E Sawyer, I Tomlinson, M Kerin, F Marme, A Schneeweiss, C Sohn, B Burwinkel, P Guenel, T Truong, E Cordina-Duverger, F Menegaux, SE Bojesen, BG Nordestgaard, SF Nielsen, H Flyger, RL Milne, MR Alonso, A Gonzalez-Neira, J Benitez, H Anton-Culver, A Ziogas, L Bernstein, CC Dur, H Brenner, H Muller, V Arndt, C Stegmaier, Familial Breast Cancer Study (FBCS), C Justenhoven, H Brauch, T Bruning, Gene Environment Interaction of Breast Cancer in Germany (GENICA) Network, Genome-wide association analysis identifies three new breast cancer susceptibility loci. Nat Genet 44, 312-318 (2012).
-
(2012)
Nat Genet
, vol.44
, pp. 312-318
-
-
Ghoussaini, M.1
Fletcher, O.2
Michailidou, K.3
Turnbull, C.4
Schmidt, M.K.5
Dicks, E.6
Dennis, J.7
Wang, Q.8
Humphreys, M.K.9
Luccarini, C.10
Baynes, C.11
Conroy, D.12
Maranian, M.13
Ahmed, S.14
Driver, K.15
Johnson, N.16
Orr, N.17
Silva, I.D.S.18
Waisfisz, Q.19
Meijers-Heijboer, H.20
Uitterlinden, A.G.21
Rivadeneira, F.22
Hall, P.23
Czene, K.24
Irwanto, A.25
Liu, J.26
Nevanlinna, H.27
Aittomaki, K.28
Blomqvist, C.29
Meindl, A.30
Schmutzler, R.K.31
Muller-Myhsok, B.32
Lichtner, P.33
Chang-Claude, J.34
Hein, R.35
Nickels, S.36
Janys D.F.-37
Tsimiklis, H.38
Makalic, E.39
Schmidt, D.40
Bui, M.41
Hopper, J.L.42
Apicella, C.43
Park, D.J.44
Southey, M.45
Hunter, D.J.46
Chanock, S.J.47
Broeks, A.48
Verhoef, S.49
Hogervorst, F.B.50
Fasching, P.A.51
Lux, M.P.52
Beckmann, M.W.53
Ekici, A.B.54
Sawyer, E.55
Tomlinson, I.56
Kerin, M.57
Marme, F.58
Schneeweiss, A.59
Sohn, C.60
Burwinkel, B.61
Guenel, P.62
Truong, T.63
Cordina-Duverger, E.64
Menegaux, F.65
Bojesen, S.E.66
Nordestgaard, B.G.67
Nielsen, S.F.68
Flyger, H.69
Milne, R.L.70
Alonso, M.R.71
Gonzalez-Neira, A.72
Benitez, J.73
Anton-Culver, H.74
Ziogas, A.75
Bernstein, L.76
Dur, C.C.77
Brenner, H.78
Muller, H.79
Arndt, V.80
Stegmaier, C.81
Justenhoven, C.82
Brauch, H.83
Bruning, T.84
more..
-
92
-
-
0034467004
-
Tyrosine kinase signalling in breast cancer fibroblast growth factors and their receptors
-
DOI 10.1186/bcr53
-
C Dickson, B Spencer-Dene, C Dillon and V Fantl: Tyrosine kinase signalling in breast cancer: fibroblast growth factors and their receptors. Breast Cancer Res 2, 191-196 (2000). (Pubitemid 32223584)
-
(2000)
Breast Cancer Research
, vol.2
, Issue.3
, pp. 191-196
-
-
Dickson, C.1
Spencer-Dene, B.2
Dillon, C.3
Fantl, V.4
-
93
-
-
34250006413
-
Genome-wide association study identifies novel breast cancer susceptibility loci
-
DOI 10.1038/nature05887, PII NATURE05887
-
DF Easton, KA Pooley, AM Dunning, PD Pharoah, D Thompson, DG Ballinger, JP Struewing, J Morrison, H Field, R Luben, N Wareham, S Ahmed, CS Healey, R Bowman, KB Meyer, CA Haiman, LK Kolonel, BE Henderson, L Le Marchand, P Brennan, S Sangrajrang, V Gaborieau, F Odefrey, CY Shen, PE Wu, HC Wang, D Eccles, DG Evans, J Peto, O Fletcher, N Johnson, S Seal, MR Stratton, N Rahman, G Chenevix-Trench, SE Bojesen, BG Nordestgaard, CK Axelsson, M Garcia-Closas, L Brinton, S Chanock, J Lissowska, B Peplonska, H Nevanlinna, R Fagerholm, H Eerola, D Kang, KY Yoo, DY Noh, SH Ahn, DJ Hunter, SE Hankinson, DG Cox, P Hall, S Wedren, J Liu, YL Low, N Bogdanova, P Schürmann, T Dörk, R A Tollenaar, CE Jacobi, P Devilee, JG Klijn, AJ Sigurdson, MM Doody, BH Alexander, J Zhang, A Cox, IW Brock, G MacPherson, MW Reed, FJ Couch, EL Goode, JE Olson, H Meijers-Heijboer, A van den Ouweland, A Uitterlinden, F Rivadeneira, RL Milne, G Ribas, A Gonzalez-Neira, J Benitez, JL Hopper, M McCredie, M Southey, GG Giles, C Schroen, C Justenhoven, H Brauch, U Hamann, YD Ko, AB Spurdle, J Beesley, X Chen, A Mannermaa, VM Kosma, V Kataja, J Hartikainen, NE Day, DR Cox, BA Ponder: Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 447(7148): 1087-1093 (2007). (Pubitemid 47014426)
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1087-1093
-
-
Easton, D.F.1
Pooley, K.A.2
Dunning, A.M.3
Pharoah, P.D.P.4
Thompson, D.5
Ballinger, D.G.6
Struewing, J.P.7
Morrison, J.8
Field, H.9
Luben, R.10
-
94
-
-
34250002140
-
Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer
-
DOI 10.1038/ng2064, PII NG2064
-
SN Stacey, A Manolescu, P Sulem, T Rafnar, J Gudmundsson, SA Gudjonsson, G Masson, M Jakobsdottir, S Thorlacius, A Helgason, KK Aben, LJ Strobbe, M Albers-Akkers, DW Swinkels, BE Henderson, LN Kolonel, L Le Marchand, E Millastre, R Andres, J Godino, MD Garcia-Prats, E Polo, A Tres, M Mouy, J Saemundsdottir, VM Backman, L Gudmundsson, K Kristjansson, J T Bergthorsson, J Kostic, M L Frigge, F Geller, D Gudbjartsson, H Sigurdsson, T Jonsdottir, J Hrafnkelsson, J Johannsson, T Sveinsson, G Myrdal, HN Grimsson, T Jonsson, S von Holst, B Werelius, S Margolin, A Lindblom, JI Mayordomo, CA Haiman, LA Kiemeney, OT Johannsson, JR Gulcher, U Thorsteinsdottir, A Kong and K Stefansson: Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet 39, 865-869 (2007). (Pubitemid 47014497)
-
(2007)
Nature Genetics
, vol.39
, Issue.7
, pp. 865-869
-
-
Stacey, S.N.1
Manolescu, A.2
Sulem, P.3
Rafnar, T.4
Gudmundsson, J.5
Gudjonsson, S.A.6
Masson, G.7
Jakobsdottir, M.8
Thorlacius, S.9
Helgason, A.10
Aben, K.K.11
Strobbe, L.J.12
Albers-Akkers, M.T.13
Swinkels, D.W.14
Henderson, B.E.15
Kolonel, L.N.16
Le Marchand, L.17
Millastre, E.18
Andres, R.19
Godino, J.20
Garcia-Prats, M.D.21
Polo, E.22
Tres, A.23
Mouy, M.24
Saemundsdottir, J.25
Backman, V.M.26
Gudmundsson, L.27
Kristjansson, K.28
Bergthorsson, J.T.29
Kostic, J.30
Frigge, M.L.31
Geller, F.32
Gudbjartsson, D.33
Sigurdsson, H.34
Jonsdottir, T.35
Hrafnkelsson, J.36
Johannsson, J.37
Sveinsson, T.38
Myrdal, G.39
Grimsson, H.N.40
Jonsson, T.41
Von Holst, S.42
Werelius, B.43
Margolin, S.44
Lindblom, A.45
Mayordomo, J.I.46
Haiman, C.A.47
Kiemeney, L.A.48
Johannsson, O.T.49
Gulcher, J.R.50
Thorsteinsdottir, U.51
Kong, A.52
Stefansson, K.53
more..
-
95
-
-
41949142377
-
Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33
-
DOI 10.1073/pnas.0800441105
-
B Gold, T Kirchhoff, S Stefanov, J Lautenberger, A Viale, J Garber, E Friedman, S Narod, AB Olshen, P Gregersen, K Kosarin, A Olsh, J Bergeron, NA Ellis, RJ Klein, AG Clark, L Norton, M Dean, J Boyd and K Offit: Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33. Proc Natl Acad Sci U S A 105, 4340-4345 (2008). (Pubitemid 351754382)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.11
, pp. 4340-4345
-
-
Gold, B.1
Kirchhoff, T.2
Stefanov, S.3
Lautenberger, J.4
Viale, A.5
Garber, J.6
Friedman, E.7
Narod, S.8
Olshen, A.B.9
Gregersen, P.10
Kosarin, K.11
Olsh, A.12
Bergeron, J.13
Ellis, N.A.14
Klein, R.J.15
Clark, A.G.16
Norton, L.17
Dean, M.18
Boyd, J.19
Offit, K.20
more..
-
96
-
-
44349087530
-
Common variants on chromosome 5p12 confer susceptibility to estrogen receptor-positive breast cancer
-
DOI 10.1038/ng.131, PII NG131
-
SN Stacey, A Manolescu, P Sulem, S Thorlacius, SA Gudjonsson, GF Jonsson, M Jakobsdottir, JT Bergthorsson, J Gudmundsson, KK Aben, LJ Strobbe, DW Swinkels, KC van Engelenburg, BE Henderson, LN Kolonel, L Le Marchand, E Millastre, R Andres, B Saez, J Lambea, J Godino, E Polo, A Tres, S Picelli, J Rantala, S Margolin, T Jonsson, H Sigurdsson, T Jonsdottir, J Hrafnkelsson, J Johannsson, T Sveinsson, G Myrdal, HN Grimsson, SG Sveinsdottir, K Alexiusdottir, J Saemundsdottir, A Sigurdsson, J Kostic, L Gudmundsson, K Kristjansson, G Masson, JD Fackenthal, C Adebamowo, T Ogundiran, OI Olopade, CA Haiman, A Lindblom, JI Mayordomo, LA Kiemeney, JR Gulcher, T Rafnar, U Thorsteinsdottir, OT Johannsson, A Kong and K Stefansson: Common variants on chromosome 5p12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet 40, 703-706 (2008). (Pubitemid 351748861)
-
(2008)
Nature Genetics
, vol.40
, Issue.6
, pp. 703-706
-
-
Stacey, S.N.1
Manolescu, A.2
Sulem, P.3
Thorlacius, S.4
Gudjonsson, S.A.5
Jonsson, G.F.6
Jakobsdottir, M.7
Bergthorsson, J.T.8
Gudmundsson, J.9
Aben, K.K.10
Strobbe, L.J.11
Swinkels, D.W.12
Van Engelenburg, K.C.A.13
Henderson, B.E.14
Kolonel, L.N.15
Le Marchand, L.16
Millastre, E.17
Andres, R.18
Saez, B.19
Lambea, J.20
Godino, J.21
Polo, E.22
Tres, A.23
Picelli, S.24
Rantala, J.25
Margolin, S.26
Jonsson, T.27
Sigurdsson, H.28
Jonsdottir, T.29
Hrafnkelsson, J.30
Johannsson, J.31
Sveinsson, T.32
Myrdal, G.33
Grimsson, H.N.34
Sveinsdottir, S.G.35
Alexiusdottir, K.36
Saemundsdottir, J.37
Sigurdsson, A.38
Kostic, J.39
Gudmundsson, L.40
Kristjansson, K.41
Masson, G.42
Fackenthal, J.D.43
Adebamowo, C.44
Ogundiran, T.45
Olopade, O.I.46
Haiman, C.A.47
Lindblom, A.48
Mayordomo, J.I.49
Kiemeney, L.A.50
Gulcher, J.R.51
Rafnar, T.52
Thorsteinsdottir, U.53
Johannsson, O.T.54
Kong, A.55
Stefansson, K.56
more..
-
97
-
-
43249123378
-
Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics
-
Australian Ovarian Cancer Management Group, Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer
-
M Garcia-Closas, P Hall, H Nevanlinna, K Pooley, J Morrison, DA Richesson, SE Bojesen, BG Nordestgaard, CK Axelsson, JI Arias, RL Milne, G Ribas, A Gonzalez-Neira, J Benitez, P Zamora, H Brauch, C Justenhoven, U Hamann, YD Ko, T Bruening, S Haas, T Dork, P Schurmann, P Hillemanns, N Bogdanova, M Bremer, JH Karstens, R Fagerholm, K Aaltonen, K Aittomaki, K von Smitten, C Blomqvist, A Mannermaa, M Uusitupa, M Eskelinen, M Tengstrom, VM Kosma, V Kataja, G Chenevix-Trench, AB Spurdle, J Beesley, X Chen, Australian Ovarian Cancer Management Group, Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer, P Devilee, CJ van Asperen, CEJacobi, RA Tollenaar, PE Huijts, JG Klijn, J Chang-Claude, S Kropp, T Slanger, D Flesch-Janys, E Mutschelknauss, R Salazar, S Wang-Gohrke, F Couch, EL Goode, JE Olson, C Vachon, Z S Fredericksen, GG Giles, L Baglietto, G Severi, JL Hopper, DR English, MC Southey, CA Haiman, BE Henderson, LN Kolonel, L Le Marchand, DO Stram, DJ Hunter, SE Hankinson, DG Cox, R Tamimi, P Kraft, ME Sherman, S J Chanock, J Lissowska, L A Brinton, B Peplonska, J G Klijn, M J Hooning, H Meijers-Heijboer, J M Collee, A van den Ouweland, AG Uitterlinden, J Liu, LY Lin, L Yuqing, K Humphreys, K Czene, A Cox, SP Balasubramanian, SS Cross, MW Reed, F Blows, K Driver, A Dunning, J Tyrer, BA Ponder, S Sangrajrang, P Brennan, J McKay, F Odefrey, V Gabrieau, A Sigurdson, M Doody, JP Struewing, B Alexander, DF Easton and PD Pharoah: Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet 4, e1000054 (2008).
-
(2008)
PLoS Genet
, vol.4
-
-
Garcia-Closas, M.1
Hall, P.2
Nevanlinna, H.3
Pooley, K.4
Morrison, J.5
Richesson, D.A.6
Bojesen, S.E.7
Nordestgaard, B.G.8
Axelsson, C.K.9
Arias, J.I.10
Milne, R.L.11
Ribas, G.12
Neira A.G.-13
Benitez, J.14
Zamora, P.15
Brauch, H.16
Justenhoven, C.17
Hamann, U.18
Ko, Y.D.19
Bruening, T.20
Haas, S.21
Dork, T.22
Schurmann, P.23
Hillemanns, P.24
Bogdanova, N.25
Bremer, M.26
Karstens, J.H.27
Fagerholm, R.28
Aaltonen, K.29
Aittomaki, K.30
Smitten, K.V.31
Blomqvist, C.32
Mannermaa, A.33
Uusitupa, M.34
Eskelinen, M.35
Tengstrom, M.36
Kosma, V.M.37
Kataja, V.38
Chenevix-Trench, G.39
Spurdle, A.B.40
Beesley, J.41
Chen, X.42
Devilee, P.43
Asperen, C.J.V.44
more..
-
98
-
-
77956193440
-
Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality
-
SM Domchek, TM Friebel, CF Singer, DG Evans, HT Lynch, C Isaacs, JE Garber, SL Neuhausen, E Matloff, R Eeles, G Pichert, L Van t'veer, N Tung, J N Weitzel, FJ Couch, WS Rubinstein, PA Ganz, MB Daly, OI Olopade, G Tomlinson, J Schildkraut, JL Blum and TR Rebbeck: Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality. JAMA 304, 967-975 (2010).
-
(2010)
JAMA
, vol.304
, pp. 967-975
-
-
Domchek, S.M.1
Friebel, T.M.2
Singer, C.F.3
Evans, D.G.4
Lynch, H.T.5
Isaacs, C.6
Garber, J.E.7
Neuhausen, S.L.8
Matloff, E.9
Eeles, R.10
Pichert, G.11
T'veer, L.V.12
Tung, N.13
Weitzel, J.N.14
Couch, F.J.15
Rubinstein, W.S.16
Ganz, P.A.17
Daly, M.B.18
Olopade, O.I.19
Tomlinson, G.20
Schildkraut, J.21
Blum, J.L.22
Rebbeck, T.R.23
more..
-
99
-
-
0037033733
-
A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes
-
DOI 10.1038/sj.bjc.6600008
-
AC Antoniou, PD Pharoah, G McMullan, NE Day, MR Stratton, J Peto, BJ Ponder and DF Easton: A comprehensive model for familial breast cancer incorporating BRCA1, BRCA2 and other genes. Br J Cancer 86, 76-83 (2002). (Pubitemid 34146344)
-
(2002)
British Journal of Cancer
, vol.86
, Issue.1
, pp. 76-83
-
-
Antoniou, A.C.1
Pharoah, P.D.P.2
McMullan, G.3
Day, N.E.4
Stratton, M.R.5
Peto, J.6
Ponder, B.J.7
Easton, D.F.8
-
100
-
-
81055126264
-
Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing
-
T Walsh, S Casadei, MK Lee, CC Pennil, AS Nord, AM Thornton, W Roeb, KJ Agnew, SM Stray, A Wickramanayake, B Norquist, KP Pennington, RL Garcia, MC King and EM Swisher: Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. Proc Natl Acad Sci U S A 108, 18032-18037 (2011).
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 18032-18037
-
-
Walsh, T.1
Casadei, S.2
Lee, M.K.3
Pennil, C.C.4
Nord, A.S.5
Thornton, A.M.6
Roeb, W.7
Agnew, K.J.8
Stray, S.M.9
Wickramanayake, A.10
Norquist, B.11
Pennington, K.P.12
Garcia, R.L.13
King, M.C.14
Swisher, E.M.15
|