DNA2 cooperates with the WRN and BLM RecQ helicases to mediate long-range DNA end resection in human cells

Journal of Biological Chemistry

Volumn 289, Issue 39, 2014, Pages 27314-27326

  Sturzenegger, Andreas ^a   Burdova, Kamila ^b   Kanagaraj, Radhakrishnan ^a,c   Levikova, Maryna ^a   Pinto, Cosimo ^a   Cejka, Petr ^a   Janscak, Pavel ^a,b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALS; REPAIR;

BIOCHEMICAL EXPERIMENTS; DOUBLE STRAND BREAKS; ENZYMATIC ACTIVITIES; HOMOLOGOUS RECOMBINATION; MAMMALIAN CELLS; MICROHOMOLOGY-MEDIATED END JOINING; RECQ HELICASES; STRAND ANNEALING;

DNA;

BLM RECQ HELICASE; BLM TOPOIII ALPHA RMI1 RMI2 PROTEIN COMPLEX; DNA2 HELICASE; DOUBLE STRANDED DNA; RECQ HELICASE; REPLICATION FACTOR A; RMI1 PROTEIN; RMI2 PROTEIN; TOPOIII ALPHA; UNCLASSIFIED DRUG; WRN RECQ HELICASE; BLOOM SYNDROME HELICASE; DNA; DNA BINDING PROTEIN; DNA HELICASE; DNA2 PROTEIN, HUMAN; EXODEOXYRIBONUCLEASE; MRE11A PROTEIN, HUMAN; MULTIENZYME COMPLEX; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; RAD50 PROTEIN, HUMAN; UBA2 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE; WRN PROTEIN, HUMAN;

5' 3' DNA END RESECTION; ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA STRAND BREAKAGE; ENZYME ACTIVITY; EPISTASIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MAMMAL CELL; NONHUMAN; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; DOUBLE STRANDED DNA BREAK; GENETICS; HEK293 CELL LINE; METABOLISM; PHYSIOLOGY;

DNA; DNA BREAKS, DOUBLE-STRANDED; DNA HELICASES; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; EPISTASIS, GENETIC; EXODEOXYRIBONUCLEASES; HEK293 CELLS; HUMANS; MULTIENZYME COMPLEXES; RECQ HELICASES; UBIQUITIN-ACTIVATING ENZYMES;

EID: 84907584670     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.578823     Document Type: Article

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