메뉴 건너뛰기




Volumn 22, Issue 2, 2015, Pages 239-252

Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes

(24)  Bhatt, Shweta a,b   Gupta, Manoj K a,b   Khamaisi, Mogher a,b   Martinez, Rachael a   Gritsenko, Marina A c   Wagner, Bridget K d   Guye, Patrick e   Busskamp, Volker a,g   Shirakawa, Jun a,b   Wu, Gongxiong a   Liew, Chong Wee a,b   Clauss, Therese R c   Valdez, Ivan a,b   El Ouaamari, Abdelfattah a,b   Dirice, Ercument a,b   Takatani, Tomozumi a,b   Keenan, Hillary A a,b   Smith, Richard D c   Church, George a   Weiss, Ron e   more..


Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA 200; MICRORNA; MIRN200 MICRORNA, HUMAN;

EID: 84938563378     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2015.07.015     Document Type: Article
Times cited : (39)

References (53)
  • 2
    • 41149094512 scopus 로고    scopus 로고
    • Regulation of DNA repair throughout the cell cycle
    • D. Branzei, and M. Foiani Regulation of DNA repair throughout the cell cycle Nat. Rev. Mol. Cell Biol. 9 2008 297 308
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 297-308
    • Branzei, D.1    Foiani, M.2
  • 3
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • M. Brownlee Biochemistry and molecular cell biology of diabetic complications Nature 414 2001 813 820
    • (2001) Nature , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 4
    • 20044376702 scopus 로고    scopus 로고
    • The pathobiology of diabetic complications: A unifying mechanism
    • M. Brownlee The pathobiology of diabetic complications: a unifying mechanism Diabetes 54 2005 1615 1625
    • (2005) Diabetes , vol.54 , pp. 1615-1625
    • Brownlee, M.1
  • 5
    • 0023950461 scopus 로고
    • Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications
    • M. Brownlee, A. Cerami, and H. Vlassara Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications N. Engl. J. Med. 318 1988 1315 1321
    • (1988) N. Engl. J. Med. , vol.318 , pp. 1315-1321
    • Brownlee, M.1    Cerami, A.2    Vlassara, H.3
  • 6
    • 65449151412 scopus 로고    scopus 로고
    • Therapies for hyperglycaemia-induced diabetic complications: From animal models to clinical trials
    • N.A. Calcutt, M.E. Cooper, T.S. Kern, and A.M. Schmidt Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trials Nat. Rev. Drug Discov. 8 2009 417 429
    • (2009) Nat. Rev. Drug Discov. , vol.8 , pp. 417-429
    • Calcutt, N.A.1    Cooper, M.E.2    Kern, T.S.3    Schmidt, A.M.4
  • 7
    • 84884817128 scopus 로고    scopus 로고
    • MicroRNAs as pharmacological targets in endothelial cell function and dysfunction
    • A. Chamorro-Jorganes, E. Araldi, and Y. Suárez MicroRNAs as pharmacological targets in endothelial cell function and dysfunction Pharmacol. Res. 75 2013 15 27
    • (2013) Pharmacol. Res. , vol.75 , pp. 15-27
    • Chamorro-Jorganes, A.1    Araldi, E.2    Suárez, Y.3
  • 10
    • 84915820764 scopus 로고    scopus 로고
    • Special delivery: MicroRNA-200-containing extracellular vesicles provide metastatic message to distal tumor cells
    • D.M. Epstein Special delivery: microRNA-200-containing extracellular vesicles provide metastatic message to distal tumor cells J. Clin. Invest. 124 2014 5107 5108
    • (2014) J. Clin. Invest. , vol.124 , pp. 5107-5108
    • Epstein, D.M.1
  • 11
    • 15844394846 scopus 로고    scopus 로고
    • Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
    • J. Falck, J. Coates, and S.P. Jackson Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage Nature 434 2005 605 611
    • (2005) Nature , vol.434 , pp. 605-611
    • Falck, J.1    Coates, J.2    Jackson, S.P.3
  • 12
    • 4143140134 scopus 로고    scopus 로고
    • Diabetic cardiomyopathy: Evidence, mechanisms, and therapeutic implications
    • Z.Y. Fang, J.B. Prins, and T.H. Marwick Diabetic cardiomyopathy: evidence, mechanisms, and therapeutic implications Endocr. Rev. 25 2004 543 567
    • (2004) Endocr. Rev. , vol.25 , pp. 543-567
    • Fang, Z.Y.1    Prins, J.B.2    Marwick, T.H.3
  • 13
    • 84872313601 scopus 로고    scopus 로고
    • Mechanisms of diabetic complications
    • J.M. Forbes, and M.E. Cooper Mechanisms of diabetic complications Physiol. Rev. 93 2013 137 188
    • (2013) Physiol. Rev. , vol.93 , pp. 137-188
    • Forbes, J.M.1    Cooper, M.E.2
  • 14
    • 0038820065 scopus 로고    scopus 로고
    • Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase i cleavage complexes
    • T. Furuta, H. Takemura, Z.Y. Liao, G.J. Aune, C. Redon, O.A. Sedelnikova, D.R. Pilch, E.P. Rogakou, A. Celeste, H.T. Chen, and et al. Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes J. Biol. Chem. 278 2003 20303 20312
    • (2003) J. Biol. Chem. , vol.278 , pp. 20303-20312
    • Furuta, T.1    Takemura, H.2    Liao, Z.Y.3    Aune, G.J.4    Redon, C.5    Sedelnikova, O.A.6    Pilch, D.R.7    Rogakou, E.P.8    Celeste, A.9    Chen, H.T.10
  • 15
    • 84862811171 scopus 로고    scopus 로고
    • Vascular dysfunction in diabetes: The endothelial progenitor cells as new therapeutic strategy
    • A. Georgescu Vascular dysfunction in diabetes: The endothelial progenitor cells as new therapeutic strategy World J. Diabetes 2 2011 92 97
    • (2011) World J. Diabetes , vol.2 , pp. 92-97
    • Georgescu, A.1
  • 19
    • 84885183542 scopus 로고    scopus 로고
    • MicroRNAs: Potential mediators and biomarkers of diabetic complications
    • M. Kato, N.E. Castro, and R. Natarajan MicroRNAs: potential mediators and biomarkers of diabetic complications Free Radic. Biol. Med. 64 2013 85 94
    • (2013) Free Radic. Biol. Med. , vol.64 , pp. 85-94
    • Kato, M.1    Castro, N.E.2    Natarajan, R.3
  • 20
    • 34547691507 scopus 로고    scopus 로고
    • Clinical factors associated with resistance to microvascular complications in diabetic patients of extreme disease duration: The 50-year medalist study
    • H.A. Keenan, T. Costacou, J.K. Sun, A. Doria, J. Cavellerano, J. Coney, T.J. Orchard, L.P. Aiello, and G.L. King Clinical factors associated with resistance to microvascular complications in diabetic patients of extreme disease duration: the 50-year medalist study Diabetes Care 30 2007 1995 1997
    • (2007) Diabetes Care , vol.30 , pp. 1995-1997
    • Keenan, H.A.1    Costacou, T.2    Sun, J.K.3    Doria, A.4    Cavellerano, J.5    Coney, J.6    Orchard, T.J.7    Aiello, L.P.8    King, G.L.9
  • 21
    • 78049320362 scopus 로고    scopus 로고
    • Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study
    • H.A. Keenan, J.K. Sun, J. Levine, A. Doria, L.P. Aiello, G. Eisenbarth, S. Bonner-Weir, and G.L. King Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study Diabetes 59 2010 2846 2853
    • (2010) Diabetes , vol.59 , pp. 2846-2853
    • Keenan, H.A.1    Sun, J.K.2    Levine, J.3    Doria, A.4    Aiello, L.P.5    Eisenbarth, G.6    Bonner-Weir, S.7    King, G.L.8
  • 24
    • 17644409069 scopus 로고    scopus 로고
    • ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
    • J.H. Lee, and T.T. Paull ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex Science 308 2005 551 554
    • (2005) Science , vol.308 , pp. 551-554
    • Lee, J.H.1    Paull, T.T.2
  • 25
    • 70350502118 scopus 로고    scopus 로고
    • Proteasome-dependent processing of topoisomerase I-DNA adducts into DNA double strand breaks at arrested replication forks
    • C.P. Lin, Y. Ban, Y.L. Lyu, and L.F. Liu Proteasome-dependent processing of topoisomerase I-DNA adducts into DNA double strand breaks at arrested replication forks J. Biol. Chem. 284 2009 28084 28092
    • (2009) J. Biol. Chem. , vol.284 , pp. 28084-28092
    • Lin, C.P.1    Ban, Y.2    Lyu, Y.L.3    Liu, L.F.4
  • 26
    • 84886056389 scopus 로고    scopus 로고
    • Metabolic modulation of chromatin: Implications for DNA repair and genomic integrity
    • J. Liu, J. Kim, and P. Oberdoerffer Metabolic modulation of chromatin: implications for DNA repair and genomic integrity Front. Genet. 4 2013 182
    • (2013) Front. Genet. , vol.4 , pp. 182
    • Liu, J.1    Kim, J.2    Oberdoerffer, P.3
  • 27
    • 84860301189 scopus 로고    scopus 로고
    • Mesenchymal stem cell-based therapy for the treatment of type 1 diabetes mellitus
    • M. Mabed, and M. Shahin Mesenchymal stem cell-based therapy for the treatment of type 1 diabetes mellitus Curr. Stem Cell Res. Ther. 7 2012 179 190
    • (2012) Curr. Stem Cell Res. Ther. , vol.7 , pp. 179-190
    • Mabed, M.1    Shahin, M.2
  • 28
    • 84888202910 scopus 로고    scopus 로고
    • Glucose metabolism, hyperosmotic stress, and reprogramming of somatic cells
    • R. Madonna, A. Görbe, P. Ferdinandy, and R. De Caterina Glucose metabolism, hyperosmotic stress, and reprogramming of somatic cells Mol. Biotechnol. 55 2013 169 178
    • (2013) Mol. Biotechnol. , vol.55 , pp. 169-178
    • Madonna, R.1    Görbe, A.2    Ferdinandy, P.3    De Caterina, R.4
  • 30
    • 79956199198 scopus 로고    scopus 로고
    • Integrating physiological regulation with stem cell and tissue homeostasis
    • D. Nakada, B.P. Levi, and S.J. Morrison Integrating physiological regulation with stem cell and tissue homeostasis Neuron 70 2011 703 718
    • (2011) Neuron , vol.70 , pp. 703-718
    • Nakada, D.1    Levi, B.P.2    Morrison, S.J.3
  • 32
    • 79955911075 scopus 로고    scopus 로고
    • Human vascular endothelial cells: A model system for studying vascular inflammation in diabetes and atherosclerosis
    • D. Onat, D. Brillon, P.C. Colombo, and A.M. Schmidt Human vascular endothelial cells: a model system for studying vascular inflammation in diabetes and atherosclerosis Curr. Diab. Rep. 11 2011 193 202
    • (2011) Curr. Diab. Rep. , vol.11 , pp. 193-202
    • Onat, D.1    Brillon, D.2    Colombo, P.C.3    Schmidt, A.M.4
  • 33
    • 0031717894 scopus 로고    scopus 로고
    • Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts
    • L. Park, K.G. Raman, K.J. Lee, Y. Lu, L.J. Ferran Jr., W.S. Chow, D. Stern, and A.M. Schmidt Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts Nat. Med. 4 1998 1025 1031
    • (1998) Nat. Med. , vol.4 , pp. 1025-1031
    • Park, L.1    Raman, K.G.2    Lee, K.J.3    Lu, Y.4    Ferran, Jr.L.J.5    Chow, W.S.6    Stern, D.7    Schmidt, A.M.8
  • 36
    • 84875198804 scopus 로고    scopus 로고
    • Chromatin remodeling at DNA double-strand breaks
    • B.D. Price, and A.D. D'Andrea Chromatin remodeling at DNA double-strand breaks Cell 152 2013 1344 1354
    • (2013) Cell , vol.152 , pp. 1344-1354
    • Price, B.D.1    D'Andrea, A.D.2
  • 37
    • 84872158502 scopus 로고    scopus 로고
    • Vascular complications of diabetes: Mechanisms of injury and protective factors
    • C. Rask-Madsen, and G.L. King Vascular complications of diabetes: mechanisms of injury and protective factors Cell Metab. 17 2013 20 33
    • (2013) Cell Metab. , vol.17 , pp. 20-33
    • Rask-Madsen, C.1    King, G.L.2
  • 38
    • 79957487252 scopus 로고    scopus 로고
    • Epigenetic mechanisms in diabetic vascular complications
    • M.A. Reddy, and R. Natarajan Epigenetic mechanisms in diabetic vascular complications Cardiovasc. Res. 90 2011 421 429
    • (2011) Cardiovasc. Res. , vol.90 , pp. 421-429
    • Reddy, M.A.1    Natarajan, R.2
  • 42
    • 23644439784 scopus 로고    scopus 로고
    • Vascular complications in diabetes mellitus: The role of endothelial dysfunction
    • C.G. Schalkwijk, and C.D. Stehouwer Vascular complications in diabetes mellitus: the role of endothelial dysfunction Clin. Sci. 109 2005 143 159
    • (2005) Clin. Sci. , vol.109 , pp. 143-159
    • Schalkwijk, C.G.1    Stehouwer, C.D.2
  • 44
    • 1342326781 scopus 로고    scopus 로고
    • Role of NF-kappaB and DNA repair protein Ku on apoptosis in pancreatic acinar cells
    • J.Y. Song, J.W. Lim, H. Kim, and K.H. Kim Role of NF-kappaB and DNA repair protein Ku on apoptosis in pancreatic acinar cells Ann. N Y Acad. Sci. 1010 2003 259 263
    • (2003) Ann. N y Acad. Sci. , vol.1010 , pp. 259-263
    • Song, J.Y.1    Lim, J.W.2    Kim, H.3    Kim, K.H.4
  • 47
    • 29244434544 scopus 로고    scopus 로고
    • MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
    • M. Stucki, J.A. Clapperton, D. Mohammad, M.B. Yaffe, S.J. Smerdon, and S.P. Jackson MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks Cell 123 2005 1213 1226
    • (2005) Cell , vol.123 , pp. 1213-1226
    • Stucki, M.1    Clapperton, J.A.2    Mohammad, D.3    Yaffe, M.B.4    Smerdon, S.J.5    Jackson, S.P.6
  • 48
    • 84856112882 scopus 로고    scopus 로고
    • Diseases in a dish: Modeling human genetic disorders using induced pluripotent cells
    • G. Tiscornia, E.L. Vivas, and J.C. Izpisúa Belmonte Diseases in a dish: modeling human genetic disorders using induced pluripotent cells Nat. Med. 17 2011 1570 1576
    • (2011) Nat. Med. , vol.17 , pp. 1570-1576
    • Tiscornia, G.1    Vivas, E.L.2    Izpisúa Belmonte, J.C.3
  • 51
    • 84868093509 scopus 로고    scopus 로고
    • The histone variant macroH2A1.1 is recruited to DSBs through a mechanism involving PARP1
    • C. Xu, Y. Xu, O. Gursoy-Yuzugullu, and B.D. Price The histone variant macroH2A1.1 is recruited to DSBs through a mechanism involving PARP1 FEBS Lett. 586 2012 3920 3925
    • (2012) FEBS Lett. , vol.586 , pp. 3920-3925
    • Xu, C.1    Xu, Y.2    Gursoy-Yuzugullu, O.3    Price, B.D.4
  • 52
    • 84870904979 scopus 로고    scopus 로고
    • Histone H2A.Z controls a critical chromatin remodeling step required for DNA double-strand break repair
    • Y. Xu, M.K. Ayrapetov, C. Xu, O. Gursoy-Yuzugullu, Y. Hu, and B.D. Price Histone H2A.Z controls a critical chromatin remodeling step required for DNA double-strand break repair Mol. Cell 48 2012 723 733
    • (2012) Mol. Cell , vol.48 , pp. 723-733
    • Xu, Y.1    Ayrapetov, M.K.2    Xu, C.3    Gursoy-Yuzugullu, O.4    Hu, Y.5    Price, B.D.6
  • 53
    • 79251612707 scopus 로고    scopus 로고
    • Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes
    • Wellcome Trust Case Control Consortium 2 MAGIC investigators
    • K. Zhou, C. Bellenguez, C.C. Spencer, A.J. Bennett, R.L. Coleman, R. Tavendale, S.A. Hawley, L.A. Donnelly, C. Schofield, C.J. Groves, et al. GoDARTS and UKPDS Diabetes Pharmacogenetics Study Group Wellcome Trust Case Control Consortium 2 MAGIC investigators Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes Nat. Genet. 43 2011 117 120
    • (2011) Nat. Genet. , vol.43 , pp. 117-120
    • Zhou, K.1    Bellenguez, C.2    Spencer, C.C.3    Bennett, A.J.4    Coleman, R.L.5    Tavendale, R.6    Hawley, S.A.7    Donnelly, L.A.8    Schofield, C.9    Groves, C.J.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.