A high proliferation rate is required for cell reprogramming and maintenance of human embryonic stem cell identity

Current Biology

Volumn 21, Issue 1, 2011, Pages 45-52

  Ruiz, Sergio ^a   Panopoulos, Athanasia D ^a   Herrerías, Aída ^b   Bissig, Karl Dimiter ^a   Lutz, Margaret ^a   Berggren, W Travis ^a   Verma, Inder M ^a   Izpisua Belmonte, Juan Carlos ^a,b  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b CENTER OF REGENERATIVE MEDICINE IN BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CYTOLOGY; EMBRYONIC STEM CELL; HUMAN; PHYSIOLOGY;

CELL CYCLE; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; EMBRYONIC STEM CELLS; HUMANS;

IPS;

EID: 79151470981     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2010.11.049     Document Type: Article

References (29)

1. J. White, and S. Dalton Cell cycle control of embryonic stem cells Stem Cell Rev. 1 2005 131 138
2. I. Neganova, and M. Lako G1 to S phase cell cycle transition in somatic and embryonic stem cells J. Anat. 213 2008 30 44
3. C. Lange, W.B. Huttner, and F. Calegari Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors Cell Stem Cell 5 2009 320 331
4. D.A. Card, P.B. Hebbar, L. Li, K.W. Trotter, Y. Komatsu, Y. Mishina, and T.K. Archer Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells Mol. Cell. Biol. 28 2008 6426 6438
5. X. Zhang, I. Neganova, S. Przyborski, C. Yang, M. Cooke, S.P. Atkinson, G. Anyfantis, S. Fenyk, W.N. Keith, and S.F. Hoare A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A J. Cell Biol. 184 2009 67 82
6. J. Lee, Y. Go, I. Kang, Y.M. Han, and J. Kim Oct-4 controls cell-cycle progression of embryonic stem cells Biochem. J. 426 2010 171 181
7. K. Takahashi, K. Tanabe, M. Ohnuki, M. Narita, T. Ichisaka, K. Tomoda, and S. Yamanaka Induction of pluripotent stem cells from adult human fibroblasts by defined factors Cell 131 2007 861 872
8. W.E. Lowry, L. Richter, R. Yachechko, A.D. Pyle, J. Tchieu, R. Sridharan, A.T. Clark, and K. Plath Generation of human induced pluripotent stem cells from dermal fibroblasts Proc. Natl. Acad. Sci. USA 105 2008 2883 2888
9. I.H. Park, R. Zhao, J.A. West, A. Yabuuchi, H. Huo, T.A. Ince, P.H. Lerou, M.W. Lensch, and G.Q. Daley Reprogramming of human somatic cells to pluripotency with defined factors Nature 451 2008 141 146
10. J. Yu, M.A. Vodyanik, K. Smuga-Otto, J. Antosiewicz-Bourget, J.L. Frane, S. Tian, J. Nie, G.A. Jonsdottir, V. Ruotti, and R. Stewart Induced pluripotent stem cell lines derived from human somatic cells Science 318 2007 1917 1920
11. A. Meissner, M. Wernig, and R. Jaenisch Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells Nat. Biotechnol. 25 2007 1177 1181
12. T. Aasen, A. Raya, M.J. Barrero, E. Garreta, A. Consiglio, F. Gonzalez, R. Vassena, J. Bilić, V. Pekarik, and G. Tiscornia Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes Nat. Biotechnol. 26 2008 1276 1284
13. E.M. Chan, S. Ratanasirintrawoot, I.H. Park, P.D. Manos, Y.H. Loh, H. Huo, J.D. Miller, O. Hartung, J. Rho, and T.A. Ince Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells Nat. Biotechnol. 27 2009 1033 1037
14. N. Maherali, T. Ahfeldt, A. Rigamonti, J. Utikal, C. Cowan, and K. Hochedlinger A high-efficiency system for the generation and study of human induced pluripotent stem cells Cell Stem Cell 3 2008 340 345
15. T.P. Zwaka, and J.A. Thomson Homologous recombination in human embryonic stem cells Nat. Biotechnol. 21 2003 319 321
16. A. Banito, S.T. Rashid, J.C. Acosta, S. Li, C.F. Pereira, I. Geti, S. Pinho, J.C. Silva, V. Azuara, and M. Walsh Senescence impairs successful reprogramming to pluripotent stem cells Genes Dev. 23 2009 2134 2139
17. R.A. Weinberg The retinoblastoma protein and cell cycle control Cell 81 1995 323 330
18. M. Malumbres, and M. Barbacid Cell cycle, CDKs and cancer: A changing paradigm Nat. Rev. Cancer 9 2009 153 166
19. E.T. Cánepa, M.E. Scassa, J.M. Ceruti, M.C. Marazita, A.L. Carcagno, P.F. Sirkin, and M.F. Ogara INK4 proteins, a family of mammalian CDK inhibitors with novel biological functions IUBMB Life 59 2007 419 426
20. T. Abbas, and A. Dutta p21 in cancer: Intricate networks and multiple activities Nat. Rev. Cancer 9 2009 400 414
21. R.S. Nowakowski, S.B. Lewin, and M.W. Miller Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population J. Neurocytol. 18 1989 311 318
22. F. Calegari, and W.B. Huttner An inhibition of cyclin-dependent kinases that lengthens, but does not arrest, neuroepithelial cell cycle induces premature neurogenesis J. Cell Sci. 116 2003 4947 4955
23. P. Salomoni, and F. Calegari Cell cycle control of mammalian neural stem cells: Putting a speed limit on G1 Trends Cell Biol. 20 2010 233 243
24. C. Lange, and F. Calegari Cdks and cyclins link G(1) length and differentiation of embryonic, neural and hematopoietic stem cells Cell Cycle 9 2010 1893 1900
25. T.E. Ludwig, V. Bergendahl, M.E. Levenstein, J. Yu, M.D. Probasco, and J.A. Thomson Feeder-independent culture of human embryonic stem cells Nat. Methods 3 2006 637 646
26. H. Li, M. Collado, A. Villasante, K. Strati, S. Ortega, M. Cañamero, M.A. Blasco, and M. Serrano The Ink4/Arf locus is a barrier for iPS cell reprogramming Nature 460 2009 1136 1139
27. H. Hong, K. Takahashi, T. Ichisaka, T. Aoi, O. Kanagawa, M. Nakagawa, K. Okita, and S. Yamanaka Suppression of induced pluripotent stem cell generation by the p53-p21 pathway Nature 460 2009 1132 1135
28. T. Kawamura, J. Suzuki, Y.V. Wang, S. Menendez, L.B. Morera, A. Raya, G.M. Wahl, and J.C. Belmonte Linking the p53 tumour suppressor pathway to somatic cell reprogramming Nature 460 2009 1140 1144
29. R.M. Marión, K. Strati, H. Li, M. Murga, R. Blanco, S. Ortega, O. Fernandez-Capetillo, M. Serrano, and M.A. Blasco A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity Nature 460 2009 1149 1153