Antiproliferative and tumor inhibitory studies of 2,3 disubstituted 4-thiazolidinone derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 17, 2015, Pages 3616-3620

  Sharath Kumar, Kothanahally S ^a   Hanumappa, Ananda ^a   Vetrivel, Maruthai ^b   Hegde, Mahesh ^a   Girish, Yarabhally R ^a   Byregowda, Thinnali R ^b   Rao, Suguna ^b   Raghavan, Sathees C ^c   Rangappa, Kanchugarakoppal S ^a  

^a UNIVERSITY OF MYSORE   (India)

^b VETERINARY COLLEGE   (India)

^c INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

4 Thiazolidinone; EAC; Reh; T3P; Tumor regression

Indexed keywords

3 (3,4 DIMETHOXYPHENYL) 2 (PYRIDIN 3 YL)THIAZOLIDIN 4 ONE; 3 (4 BROMOPHENYL) 2 [4 (DIMETHYLAMINO)PHENYL]THIAZOLIDIN 4 ONE; 4 THIAZOLIDINONE DERIVATIVE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; THIAZOLIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC50; LEUKEMIA CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; SUBSTITUTION REACTION; TUMOR VOLUME; ANIMAL; CELL PROLIFERATION; CHEMISTRY; DRUG DESIGN; DRUG EFFECTS; LEUKEMIA; NEOPLASMS; PATHOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LEUKEMIA; MICE; NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLIDINES;

EID: 84938287501     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.06.069     Document Type: Article

References (30)

1. D. Kaminskyy, B. Zimenkovsky, and R. Lesyk Eur. J. Med. Chem. 44 2009 3627
2. K.S. Sharath Kumar, C.D. Mohan, S. Jagadish, K.S. Rakesh, H. Ananda, Basappa, and K.S. Rangappa Asian J. Pharm Clin. Res. 8 1 2015 142 148
3. M.L. Barreca, A. Chimirri, L. De Luca, A.M. Monforte, P. Monforte, A. Rao, M. Zappala, J. Balzarini, E. De Clercq, C. Pannecouque, and M. Witvrouw Bioorg. Med. Chem. Lett. 11 2001 1793
4. K.M. Amin, D.E. Rahman, and Y.A. Al-Eryani Bioorg. Med. Chem. 16 2008 5377
5. S.V. Bhandari, K.G. Bothara, A.A. Patil, T.S. Chitre, A.P. Sarkate, S.T. Gore, S.C. Dangre, and C.V. Khachane Bioorg. Med. Chem. 17 2009 390
6. R. Ottana, E. Mazzon, L. Dugo, F. Monforte, R. Maccari, L. Sautebin, G. De Luca, M.G. Vigorita, S. Alcaro, F. Ortuso, A.P. Caputi, and S. Cuzzocrea Eur. J. Pharmacol. 448 2002 71
7. R. Ottana, R. Maccari, M. Giglio, A. Del Corso, M. Cappiello, U. Mura, S. Cosconati, L. Marinelli, E. Novellino, S. Sartini, C. La Motta, and F. Da Settimo Eur. J. Med. Chem. 46 2011 2797
8. M.J. Joy, N. Jacob, and N.G. Kutty Indian Drugs 42 2005 47
9. H.B. Felise, H.V. Nguyen, R.A. Pfuetzner, K.C. Barry, S.R. Jackson, M.P. Blanc, P.A. Bronstein, T. Kline, and S.I. Miller Cell Host Microbe 4 2008 325
10. G. Aridoss, S. Amirthaganesan, M.S. Kim, J.T. Kim, and Y.T. Jeong Eur. J. Med. Chem. 44 2009 4199
11. E.E. Carlson, J.F. May, and L.L. Kiessling Chem. Biol. 13 2006 825
12. J. Wrobel, J. Jetter, W. Kao, J. Rogers, L. Di, J. Chi, M.C. Perez, G.C. Chen, and E.S. Shen Bioorg. Med. Chem. 14 2006 5729
13. A.M. Panico, P. Vicini, A. Geronikaki, M. Incerti, V. Cardile, L. Crasci, R. Messina, and S. Ronsisvalle Bioorg. Chem. 39 2011 48
14. O. Mazzoni, A.M. di Bosco, P. Grieco, E. Novellino, A. Bertamino, F. Borrelli, R. Capasso, and M.V. Diurno Chem. Biol. Drug Des. 67 2006 432
15. J.W. Huang, C.W. Shiau, J. Yang, D.S. Wang, H.C. Chiu, C.Y. Chen, and C.S. Chen J. Med. Chem. 49 2006 4684
16. N.S. Cutshall, C. O'Day, and M. Prezhdo Bioorg. Med. Chem. Lett. 15 2005 3374
17. P.H. Carter, P.A. Scherle, J.A. Muckelbauer, M.E. Voss, R.-Q. Liu, L.A. Thompson, A.J. Tebben, K.A. Solomon, Y.C. Lo, Z. Li, P. Strzemienski, G. Yang, N. Falahatpisheh, M. Xu, Z. Wu, N.A. Farrow, K. Ramnarayan, J. Wang, D. Rideout, V. Yalamoori, P. Domaille, D.J. Underwood, J.M. Trzaskos, S.M. Friedman, R.C. Newton, and C.P. Decicco Proc. Natl. Acad. Sci. U.S.A. 98 2001 11879
18. A. Degterev, A. Lugovskoy, M. Cardone, B. Mulley, G. Wagner, T. Mitchison, and J. Yuan Nat. Cell Biol. 3 2001 173
19. R. Dayam, F. Aiello, J. Deng, Y. Wu, A. Garofalo, X. Chen, and N. Neamati J. Med. Chem. 49 2006 4526
20. R. Ottana, S. Carotti, R. Maccari, I. Landini, G. Chiricosta, B. Caciagli, M.G. Vigorita, and E. Mini Bioorg. Med. Chem. Lett. 15 2005 3930
21. S. Chen, L. Chen, N.T. Le, C. Zhao, A. Sidduri, J.P. Lou, C. Michoud, L. Portland, N. Jackson, J.J. Liu, F. Konzelmann, F. Chi, C. Tovar, Q. Xiang, Y. Chen, Y. Wen, and L.T. Vassilev Bioorg. Med. Chem. Lett. 17 2007 2134
22. N. Suresh, H.N. Nagesh, K.V. Sekhar, A. Kumar, A.N. Shirazi, and K. Parang Bioorg. Med. Chem. Lett. 23 2013 6292
23. K.H. Narasimhamurthy, S. Chandrappa, K.S. Sharath Kumar, T.R. Swaroop, and K.S. Rangappa Chem. Lett. 42 2013 1073
24. K.H. Narasimhamurthy, S. Chandrappa, K.S. Sharath Kumar, K.B. Harsha, H. Ananda, and K.S. Rangappa RSC Adv. 4 2014 34479
25. Y.R. Girish, K.S. Sharath Kumar, M. Umashankar, N.K. Lokanath, K.S. Rangappa, and S. Shashikanth RSC Adv. 4 2014 55800
26. G.S. Lingaraju, T.R. Swaroop, and A.C. Vinayaka Synthesis 44 2012 1373
27. K.S. Sharath Kumar, T.R. Swaroop, K.B. Harsha, K.H. Narasimhamurthy, and K.S. Rangappa Tetrahedron Lett. 53 42 2012 5619
28. K.S. Sharath Kumar, H. Ananda, M. Hegde, K.H. Narasimhamurthy, S.C. Raghavan, and K.S. Rangappa Eur. J. Med. Chem. 81 2014 341
29. C.V. Kavitha, M. Nambiar, C.S. Ananda Kumar, B. Choudhary, K. Muniyappa, K.S. Rangappa, and S.C. Raghavan Biochem. Pharmacol. 77 2009 348
30. M. Hegde, S.S. Karki, E. Thomas, S. Kumar, K. Panjamurthy, S.R. Ranganatha, K.S. Rangappa, B. Choudhary, and S.C. Raghavan PLoS One 7 2012 43632