SCOPUS 정보 검색 플랫폼

Volumn 81, Issue , 2014, Pages 341-349

Synthesis and antiproliferative effect of novel 4-thiazolidinone-, pyridine- and piperazine-based conjugates on human leukemic cells

(6) Sharath Kumar, Kothanahally S a Hanumappa, Ananda a Hegde, Mahesh a Narasimhamurthy, Kereyagalahally H a Raghavan, Sathees C b Rangappa, Kanchugarakoppal S a

a UNIVERSITY OF MYSORE (India)

b INDIAN INSTITUTE OF SCIENCE (India)

Author keywords

Apoptosis; Chemotherapeutics; Cytotoxicity; Leukemia; Thiazolidinones

Indexed keywords

4 THIAZOLIDINONE DERIVATIVE; METHYL 3 METHOXY 4 [3 [5 [4 (3 METHYLBENZYL)PIPERAZIN 1 YL]PYRIDIN 2 YL] 4 OXOTHIAZOLIDIN 2 YL]BENZOATE; METHYL 3 METHOXY 4 [3 [5 [4 (3 NITROBENZYL)PIPERAZIN 1 YL]PYRIDIN 2 YL] 4 OXOTHIAZOLIDIN 2 YL]BENZOATE; METHYL 3 METHOXY 4 [3 [5 [4 (4 METHOXYPHENYLSULFONYL)PIPERAZIN 1 YL]PYRIDIN 2 YL] 4 OXOTHIAZOLIDIN 2 YL]BENZOATE; METHYL 3 METHOXY 4 [3 [5 [4 (4 NITROPHENYLSULFONYL)PIPERAZIN 1 YL]PYRIDIN 2 YL] 4 OXOTHIAZOLIDIN 2 YL]BENZOATE; METHYL 3 METHOXY 4 [4 OXO 3 [5 (PIPERAZIN 1 YL)PYRIDIN 2 YL]THIAZOLIDIN 2 YL]BENZOATE; METHYL 3 METHOXY 4 [4 OXO 3 [5 [4 (3,4,5 TRIMETHOXYBENZYL)PIPERAZIN 1 YL]PYRIDIN 2 YL]THIAZOLIDIN 2 YL]BENZOATE; METHYL 4 [3 [5 [4 (2,5 DICHLOROPHENYLSULFONYL)PIPERAZIN 1 YL]PYRIDIN 2 YL] 4 OXOTHIAZOLIDIN 2 YL] 3 METHOXYBENZOATE; METHYL 4 [3 [5 [4 (3,4 DICHLOROBENZYL)PIPERAZIN 1 YL]PYRIDIN 2 YL] 4 OXOTHIAZOLIDIN 2 YL] 3 METHOXYBENZOATE; METHYL 4 [3 [5 [4 (4 FLUOROPHENYLSULFONYL)PIPERAZIN 1 YL]PYRIDIN 2 YL] 4 OXOTHIAZOLIDIN 2 YL] 3 METHOXYBENZOATE; METHYL 4 [3 [5 [4 (4 MESITYLSULFONYL)PIPERAZIN 1 YL]PYRIDIN 2 YL] 4 OXOTHIAZOLIDIN 2 YL] 3 METHOXYBENZOATE; PIPERAZINE DERIVATIVE; PYRIDINE DERIVATIVE; TERT BUTYL 4 (6 AMINOPYRIDIN 3 YL)PIPERAZINE 1 CARBOXYLATE; TERT BUTYL 4 (6 NITROPYRIDIN 3 YL)PIPERAZINE 1 CARBOXYLATE; TERT BUTYL 4 [6 [2 [2 METHOXY 4 (METHOXYCARBONYL)PHENYL] 4 OXOTHIAZOLIDIN 3 YL]PYRIDIN 3 YL]PIPERAZINE 1 CARBOXYLATE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; PIPERAZINE; PYRIDINE; THIAZOLIDINE DERIVATIVE;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL CYCLE; CELL DEATH; CHEMICAL STRUCTURE; CONJUGATE; CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; INFRARED SPECTROSCOPY; JURKAT CELL LINE; LEUKEMIA CELL; LEUKEMIA CELL LINE; MASS SPECTROMETRY; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTON NUCLEAR MAGNETIC RESONANCE; APOPTOSIS; CELL PROLIFERATION; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; K562 CELL LINE; LEUKEMIA; PATHOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL CULTURE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; K562 CELLS; LEUKEMIA; MEMBRANE POTENTIAL, MITOCHONDRIAL; MOLECULAR STRUCTURE; PIPERAZINES; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLIDINES; TUMOR CELLS, CULTURED;

EID: 84901345642 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2014.05.009 Document Type: Article

Times cited : (54)

References (26)

1
- 84892586858
- Q. Su, S. Ioannidis, C. Chuaqui, L. Almeida, M. Alimzhanov, G. Bebernitz, K. Bell, M. Block, T. Howard, S. Huang, D. Huszar, J.A. Read, C. Rivard Costa, J. Shi, M. Su, M. Ye, and M. Zinda J. Med. Chem. 57 2014 144
- (2014) J. Med. Chem. , vol.57 , pp. 144
- Su, Q.¹ Ioannidis, S.² Chuaqui, C.³ Almeida, L.⁴ Alimzhanov, M.⁵ Bebernitz, G.⁶ Bell, K.⁷ Block, M.⁸ Howard, T.⁹ Huang, S.¹⁰ Huszar, D.¹¹ Read, J.A.¹² Rivard Costa, C.¹³ Shi, J.¹⁴ Su, M.¹⁵ Ye, M.¹⁶ Zinda, M.¹⁷

2
- 0033602129
- R. Lan, Q. Liu, P. Fan, S. Lin, S.R. Fernando, D. McCallion, R. Pertwee, and A. Makriyannis J. Med. Chem. 42 1999 769
- (1999) J. Med. Chem. , vol.42 , pp. 769
- Lan, R.¹ Liu, Q.² Fan, P.³ Lin, S.⁴ Fernando, S.R.⁵ McCallion, D.⁶ Pertwee, R.⁷ Makriyannis, A.⁸

3
- 0344550360
- T. Nakamura, M. Sato, H. Kakinuma, N. Miyata, K. Taniguchi, K. Bando, A. Koda, and K. Kameo J. Med. Chem. 46 2003 5416
- (2003) J. Med. Chem. , vol.46 , pp. 5416
- Nakamura, T.¹ Sato, M.² Kakinuma, H.³ Miyata, N.⁴ Taniguchi, K.⁵ Bando, K.⁶ Koda, A.⁷ Kameo, K.⁸

4
- 41649106654
- H. Zhou, S. Wu, S. Zhai, A. Liu, Y. Sun, R. Li, Y. Zhang, S. Ekins, P.W. Swaan, B. Fang, B. Zhang, and B. Yan J. Med. Chem. 51 2008 1242
- (2008) J. Med. Chem. , vol.51 , pp. 1242
- Zhou, H.¹ Wu, S.² Zhai, S.³ Liu, A.⁴ Sun, Y.⁵ Li, R.⁶ Zhang, Y.⁷ Ekins, S.⁸ Swaan, P.W.⁹ Fang, B.¹⁰ Zhang, B.¹¹ Yan, B.¹²

5
- 5344277530
- H. Chen, Y.H. Fan, A. Natarajan, Y. Guo, J. Iyasere, F. Harbinski, L. Luus, W. Christ, H. Aktas, and J.A. Halperin Bioorg. Med. Chem. Lett. 14 2004 5401
- (2004) Bioorg. Med. Chem. Lett. , vol.14 , pp. 5401
- Chen, H.¹ Fan, Y.H.² Natarajan, A.³ Guo, Y.⁴ Iyasere, J.⁵ Harbinski, F.⁶ Luus, L.⁷ Christ, W.⁸ Aktas, H.⁹ Halperin, J.A.¹⁰

6
- 5344259691
- V. Gududuru, E. Hurh, J.T. Dalton, and D.D. Miller Bioorg. Med. Chem. Lett. 14 2004 5289
- (2004) Bioorg. Med. Chem. Lett. , vol.14 , pp. 5289
- Gududuru, V.¹ Hurh, E.² Dalton, J.T.³ Miller, D.D.⁴

7
- 0037334476
- M.G. Vigorita, R. Ottana, F. Monforte, R. Maccari, M.T. Monforte, A. Trovato, M.F. Taviano, N. Miceli, G. De Luca, S. Alcaro, and F. Ortuso Bioorg. Med. Chem. 11 2003 999
- (2003) Bioorg. Med. Chem. , vol.11 , pp. 999
- Vigorita, M.G.¹ Ottana, R.² Monforte, F.³ Maccari, R.⁴ Monforte, M.T.⁵ Trovato, A.⁶ Taviano, M.F.⁷ Miceli, N.⁸ De Luca, G.⁹ Alcaro, S.¹⁰ Ortuso, F.¹¹

8
- 34250159079
- S. Bondock, W. Khalifa, and A.A. Fadda Eur. J. Med. Chem. 42 2007 948
- (2007) Eur. J. Med. Chem. , vol.42 , pp. 948
- Bondock, S.¹ Khalifa, W.² Fadda, A.A.³

9
- 33847006083
- Archana, V.K. Srivastava, and A. Kumar Ind. J. Pharm. Sci. 65 2003 358
- (2003) Ind. J. Pharm. Sci. , vol.65 , pp. 358
- Archana¹ Srivastava, V.K.² Kumar, A.³

10
- 0041532819
- H.-L. Liu, Z. Lieberzeit, and T. Anthonsen Mol: A J. Synth. Chem. Nat. Prod. Chem. [Mol. (Basel, Switzerland)] 5 2000 1055
- (2000) Mol: A J. Synth. Chem. Nat. Prod. Chem. [Mol. (Basel, Switzerland)] , vol.5 , pp. 1055
- Liu, H.-L.¹ Lieberzeit, Z.² Anthonsen, T.³

11
- 33646447042
- S.G. Kucukguzel, A. Kocatepe, E. De Clercq, F. Sahin, and M. Gulluce Eur. J. Med. Chem. 41 2006 353
- (2006) Eur. J. Med. Chem. , vol.41 , pp. 353
- Kucukguzel, S.G.¹ Kocatepe, A.² De Clercq, E.³ Sahin, F.⁴ Gulluce, M.⁵

12
- 84869085237
- H. Chen, T. Yang, S. Wei, H. Zhang, R. Li, Z. Qin, and X. Li Bioorg. Med. Chem. Lett. 22 2012 7041
- (2012) Bioorg. Med. Chem. Lett. , vol.22 , pp. 7041
- Chen, H.¹ Yang, T.² Wei, S.³ Zhang, H.⁴ Li, R.⁵ Qin, Z.⁶ Li, X.⁷

13
- 34250186053
- J. Balzarini, B. Orzeszko, J.K. Maurin, and A. Orzeszko Eur. J. Med. Chem. 42 2007 993
- (2007) Eur. J. Med. Chem. , vol.42 , pp. 993
- Balzarini, J.¹ Orzeszko, B.² Maurin, J.K.³ Orzeszko, A.⁴

14
- 84865707024
- M. Mushtaque, F. Avecilla, and A. Azam Eur. J. Med. Chem. 55 2012 439
- (2012) Eur. J. Med. Chem. , vol.55 , pp. 439
- Mushtaque, M.¹ Avecilla, F.² Azam, A.³

15
- 77957844111
- D. Havrylyuk, L. Mosula, B. Zimenkovsky, O. Vasylenko, A. Gzella, and R. Lesyk Eur. J. Med. Chem. 45 2010 5012
- (2010) Eur. J. Med. Chem. , vol.45 , pp. 5012
- Havrylyuk, D.¹ Mosula, L.² Zimenkovsky, B.³ Vasylenko, O.⁴ Gzella, A.⁵ Lesyk, R.⁶

16
- 84890446471
- A.C. Tripathi, S.J. Gupta, G.N. Fatima, P.K. Sonar, and A. Verma Eur. J. Med. Chem. 72 2014 52
- (2014) Eur. J. Med. Chem. , vol.72 , pp. 52
- Tripathi, A.C.¹ Gupta, S.J.² Fatima, G.N.³ Sonar, P.K.⁴ Verma, A.⁵

17
- 78649498664
- Y.S. Cho, M. Borland, C. Brain, C.H. Chen, H. Cheng, R. Chopra, K. Chung, J. Groarke, G. He, Y. Hou, S. Kim, S. Kovats, Y. Lu, M. O'Reilly, J. Shen, T. Smith, G. Trakshel, M. Vögtle, M. Xu, M. Xu, and M.J. Sung J. Med. Chem. 53 2010 7938
- (2010) J. Med. Chem. , vol.53 , pp. 7938
- Cho, Y.S.¹ Borland, M.² Brain, C.³ Chen, C.H.⁴ Cheng, H.⁵ Chopra, R.⁶ Chung, K.⁷ Groarke, J.⁸ He, G.⁹ Hou, Y.¹⁰ Kim, S.¹¹ Kovats, S.¹² Lu, Y.¹³ O'Reilly, M.¹⁴ Shen, J.¹⁵ Smith, T.¹⁶ Trakshel, G.¹⁷ Vögtle, M.¹⁸ Xu, M.¹⁹ Xu, M.²⁰ Sung, M.J.²¹ more..

18
- 20244365948
- P.L. Toogood, P.J. Harvey, J.T. Repine, D.J. Sheehan, S.N. VanderWel, H. Zhou, P.R. Keller, D.J. McNamara, D. Sherry, T. Zhu, J. Brodfuehrer, C. Choi, M.R. Barvian, and D.W. Fry J. Med. Chem. 48 2005 2388
- (2005) J. Med. Chem. , vol.48 , pp. 2388
- Toogood, P.L.¹ Harvey, P.J.² Repine, J.T.³ Sheehan, D.J.⁴ Vanderwel, S.N.⁵ Zhou, H.⁶ Keller, P.R.⁷ McNamara, D.J.⁸ Sherry, D.⁹ Zhu, T.¹⁰ Brodfuehrer, J.¹¹ Choi, C.¹² Barvian, M.R.¹³ Fry, D.W.¹⁴

19
- 62149135930
- S. Chandrappa, C.V. Kavitha, M.S. Shahabuddin, K. Vinaya, C.S. Ananda Kumar, S.R. Ranganatha, S.C. Raghavan, and K.S. Rangappa Bioorg. Med. Chem. 17 2009 2576
- (2009) Bioorg. Med. Chem. , vol.17 , pp. 2576
- Chandrappa, S.¹ Kavitha, C.V.² Shahabuddin, M.S.³ Vinaya, K.⁴ Ananda Kumar, C.S.⁵ Ranganatha, S.R.⁶ Raghavan, S.C.⁷ Rangappa, K.S.⁸

20
- 40949136106
- Y. Imaeda, T. Kawamoto, M. Tobisu, N. Konishi, K. Hiroe, M. Kawamura, T. Tanaka, and K. Kubo Bioorg. Med. Chem. 16 2008 3125
- (2008) Bioorg. Med. Chem. , vol.16 , pp. 3125
- Imaeda, Y.¹ Kawamoto, T.² Tobisu, M.³ Konishi, N.⁴ Hiroe, K.⁵ Kawamura, M.⁶ Tanaka, T.⁷ Kubo, K.⁸

21
- 84866254447
- K.S. Sharath Kumar, T.R. Swaroop, K.B. Harsha, K.H. Narasimhamurthy, and K.S. Rangappa Tetrahedron Lett. 42 2012 5619
- (2012) Tetrahedron Lett. , vol.42 , pp. 5619
- Sharath Kumar, K.S.¹ Swaroop, T.R.² Harsha, K.B.³ Narasimhamurthy, K.H.⁴ Rangappa, K.S.⁵

22
- 84871550828
- M. Srivastava, M. Nambiar, S. Sharma, S.S. Karki, G. Goldsmith, M. Hegde, S. Kumar, M. Pandey, R.K. Singh, P. Ray, R. Natarajan, M. Kelkar, A. De, B. Choudhary, and S.C. Raghavan Cell 151 2012 1474
- (2012) Cell , vol.151 , pp. 1474
- Srivastava, M.¹ Nambiar, M.² Sharma, S.³ Karki, S.S.⁴ Goldsmith, G.⁵ Hegde, M.⁶ Kumar, S.⁷ Pandey, M.⁸ Singh, R.K.⁹ Ray, P.¹⁰ Natarajan, R.¹¹ Kelkar, M.¹² De, A.¹³ Choudhary, B.¹⁴ Raghavan, S.C.¹⁵

23
- 56649100467
- K.K. Chiruvella, V. Kari, B. Choudhary, M. Nambiar, R.G. Ghanta, and S.C. Raghavan FEBS Lett. 582 2008 4066
- (2008) FEBS Lett. , vol.582 , pp. 4066
- Chiruvella, K.K.¹ Kari, V.² Choudhary, B.³ Nambiar, M.⁴ Ghanta, R.G.⁵ Raghavan, S.C.⁶

24
- 58249144190
- C.V. Kavitha, M. Nambiar, C.S. Ananda Kumar, B. Choudhary, K. Muniyappa, K.S. Rangappa, and S.C. Raghavan Biochem. Pharmacol. 77 2009 348
- (2009) Biochem. Pharmacol. , vol.77 , pp. 348
- Kavitha, C.V.¹ Nambiar, M.² Ananda Kumar, C.S.³ Choudhary, B.⁴ Muniyappa, K.⁵ Rangappa, K.S.⁶ Raghavan, S.C.⁷

25
- 84877105796
- M. Hegde, S.S. Karki, E. Thomas, S. Kumar, K. Panjamurthy, S.R. Ranganatha, K.S. Rangappa, B. Choudhary, and S.C. Raghavan Plos One 7 2012 43632
- (2012) Plos One , vol.7 , pp. 43632
- Hegde, M.¹ Karki, S.S.² Thomas, E.³ Kumar, S.⁴ Panjamurthy, K.⁵ Ranganatha, S.R.⁶ Rangappa, K.S.⁷ Choudhary, B.⁸ Raghavan, S.C.⁹

26
- 80052608058
- K. Vinaya, C.V. Kavitha, S. Chandrappa, D.S. Prasanna, S.C. Raghavan,K.S. Rangappa, Chem. Biol. Drug Des. 78 (2011) 622.
- (2011) Chem. Biol. Drug Des. , vol.78 , pp. 622
- Vinaya, K.¹ Kavitha, C.V.² Chandrappa, S.³ Prasanna, D.S.⁴ Raghavan, S.C.⁵ Rangappa, K.S.⁶

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