Development of small-molecule cyclin D1-ablative agents

Journal of Medicinal Chemistry

Volumn 49, Issue 15, 2006, Pages 4684-4689

  Huang, Jui Wen ^a   Shiau, Chung Wai ^a   Yang, Jian ^a   Wang, Da Sheng ^a   Chiu, Hao Chieh ^a   Chen, Ching Yu ^b,c   Chen, Ching Shih ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; 5 [4 [(6 ALLYLOXY 2,5,7,8 TETRAMETHYLCHROMAN 2 YL)METHOXY] 3 METHOXYBENZYLIDENE]THIAZOLIDINE 2,4 DIONE; ANTINEOPLASTIC AGENT; BETA ACTIN; CYCLIN D1; CYCLIN DEPENDENT KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PROTEASOME; STG 28; TROGLITAZONE; UNCLASSIFIED DRUG;

ARTICLE; CANCER RESISTANCE; CARCINOGENESIS; CELL PROLIFERATION; CELL STRAIN MCF 7; CHEMICAL BOND; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; PROTEIN DEGRADATION; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; BENZOPYRANS; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMANS; CYCLIN D1; HUMANS; HYDROLYSIS; MOLECULAR CONFORMATION; PPAR GAMMA; PROTEASOME ENDOPEPTIDASE COMPLEX; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLIDINEDIONES;

EID: 33746746418     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm060057h     Document Type: Article

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