Synthesis and preliminary evaluation of some substituted coumarins as anticonvulsant agents

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 10, 2008, Pages 5377-5388

  Amin, Kamelia M ^a   Rahman, Doaa E Abdel ^a   Al Eryani, Yasmin A ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

Anticonvulsant; Chromeno 6,5 d thiazoles; Coumarinylthiazolidin 4 ones; Coumarinylthiazolines; Coumarinylthioureas

Indexed keywords

3 ETHYL 4 (4 METHOXYPHENYL) 2 (2 OXO 2H CHROMEN 6 YLIMINO)THIAZOLINE; ANTICONVULSIVE AGENT; CHROMENOTHIAZOLE DERIVATIVE; COUMARIN DERIVATIVE; COUMARINYLTHIAZOLIDIN 4 ONE DERIVATIVE; COUMARINYLTHIAZOLINE DERIVATIVE; PENTETRAZOLE; PHENOBARBITAL; STRYCHNINE; THIAZOLINE 5 CARBOXYLIC ACID ETHYL ESTER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; LIPOPHILICITY; MOUSE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; SEIZURE;

ANIMALS; ANTICONVULSANTS; COUMARINS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MICE; MOLECULAR STRUCTURE; PENTYLENETETRAZOLE; SEIZURES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; STRYCHNINE;

MUS; STRYCHNOS TOXIFERA;

EID: 43749087807     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.04.021     Document Type: Article

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