An easy access to 4,5-disubstituted thiazoles via base-induced click reaction of active methylene isocyanides with methyl dithiocarboxylates

Synthesis

Volumn 44, Issue 9, 2012, Pages 1373-1379

  Lingaraju, Gejjalagere S ^a   Swaroop, Toreshettahally R ^a   Vinayaka, Ajjampura C ^a   Sharath Kumar, Kothanahally S ^a   Sadashiva, Marilinganadoddi P ^a   Rangappa, Kanchugarakoppal S ^a  

^a UNIVERSITY OF MYSORE   (India)

Author keywords

click reaction; cyclization; dithioester; isocyanide; thiazole

Indexed keywords

CLICK CHEMISTRY; CLICK REACTION; DITHIOESTERS; EFFICIENT SYNTHESIS; ISOCYANIDES; THIAZOLE;

CYANIDES; SYNTHESIS (CHEMICAL);

CYCLIZATION;

1 METHYL 3 (4 PHENYLTHIAZOL 5 YL) 1H INDOLE; 1 METHYL 3 [4 [(4 METHYLPHENYL)SULFONYL]THIAZOL 5 YL] 1H INDOLE; 4 (4 FLUOROPHENYL) 5 (1 METHYL 1H PYRROL 2 YL)THIAZOLE; 4 (4 FLUOROPHENYL) 5 (3,4,5 TRIMETHOXYPHENYL)THIAZOLE; 4 (4 FLUOROPHENYL) 5 (4 METHOXYPHENYL)THIAZOLE; 4 (4 FLUOROPHENYL) 5 PHENYLTHIAZOLE; 4 [(4 METHYLPHENYL)SULFONYL] 5 (3,4,5 TRIMETHOXYPHENYL)THIAZOLE; 4 [(4 METHYLPHENYL)SULFONYL] 5 (THIOPHEN 2 YL)THIAZOLE; 4 [(4 METHYLPHENYL)SULFONYL] 5 PHENYLTHIAZOLE; 4 PHENYL 5 (3,4,5 TRIMETHOXYPHENYL)THIAZOLE; 4,5 DIPHENYLTHIAZOLE; 5 (1 METHYL 1H PYRROL 2 YL) 4 PHENYLTHIAZOLE; 5 (3,4 DIMETHOXYPHENYL) 4 [(4 METHYLPHENYL)SULFONYL]THIAZOLE; 5 (3,4 DIMETHOXYPHENYL) 4 PHENYLTHIAZOLE; 5 (4 CHLOROPHENYL) 4 [(4 METHYLPHENYL)SULFONYL]THIAZOLE; 5 (4 METHOXYPHENYL) 4 [(4 METHYLPHENYL)SULFONYL]THIAZOLE; 5 (4 METHOXYPHENYL) 4 PHENYLTHIAZOLE; 5 (4 METHYLPHENYL) 4 [(4 METHYLPHENYL)SULFONYL]THIAZOLE; 5 (4 METHYLPHENYL) 4 PHENYLTHIAZOLE; CARBOXYLIC ACID DERIVATIVE; CYANAMIDE; ETHYL 5 (1 METHYL 1H PYRROL 2 YL)THIAZOLE 4 CARBOXYLIC ACID; ETHYL 5 (3,4,5 TRIMETHOXYPHENYL)THIAZOLE 4 CARBOXYLIC ACID; ETHYL 5 PHENYL 1,4 THIAZOLE 4 CARBOXYLIC ACID; METHYL DITHIOCARBOXYLIC ACID DERIVATIVE; METHYLENE ISOCYANMIDE DERIVATIVE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CLICK CHEMISTRY; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; SUBSTITUTION REACTION;

EID: 84859412436     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0031-1290762     Document Type: Article

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