Anti-tumoral effect of desmethylclomipramine in lung cancer stem cells

Oncotarget

Volumn 6, Issue 19, 2015, Pages 16926-16938

  Bongiorno Borbone, Lucilla ^a   Giacobbe, Arianna ^a   Compagnone, Mirco ^a   Eramo, Adriana ^b   De Maria, Ruggero ^c   Peschiaroli, Angelo ^d   Melino, Gerry ^a,e  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^c REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^d CNR   (Italy)

^e UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Chemoresistance; DCMI; Itch inhibitor; Non small lung cancer stem cells

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALDEHYDE DEHYDROGENASE; CASPASE 3; CD133 ANTIGEN; CELL PROTEIN; CISPLATIN; GEMCITABINE; ITCH PROTEIN; LIGHT 1 CHAIN 2 PROTEIN; NORCLOMIPRAMINE; PACLITAXEL; PROTEIN P62; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CLOMIPRAMINE; ITCH PROTEIN, HUMAN; REPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER PROGNOSIS; CANCER STEM CELL; CANCER SURVIVAL; CELL COUNT; CELL PROLIFERATION; CELL SIZE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG POTENTIATION; DRUG RESISTANCE; ENZYME ACTIVITY; HOMEOSTASIS; HUMAN; HUMAN CELL; LUNG CANCER; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; ADENOCARCINOMA; ANALOGS AND DERIVATIVES; CELL CULTURE; DRUG EFFECTS; FLOW CYTOMETRY; GENETICS; KAPLAN MEIER METHOD; LUNG TUMOR; MORTALITY; PATHOLOGY; RNA INTERFERENCE; TUMOR CELL LINE; WESTERN BLOTTING;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; CELLS, CULTURED; CLOMIPRAMINE; DRUG RESISTANCE, NEOPLASM; FLOW CYTOMETRY; HUMANS; KAPLAN-MEIER ESTIMATE; LUNG NEOPLASMS; NEOPLASTIC STEM CELLS; REPRESSOR PROTEINS; RNA INTERFERENCE; UBIQUITIN-PROTEIN LIGASES;

EID: 84938263392     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4700     Document Type: Article

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