P53 induces skin aging by depleting Blimp1+ sebaceous gland cells

Cell Death and Disease

Volumn 5, Issue 3, 2014, Pages

  Kim, J ^a   Nakasaki, M ^b   Todorova, D ^a   Lake, B ^a   Yuan, C Y ^a   Jamora, C ^b   Xu, Y ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b SECTION OF CELL AND DEVELOPMENTAL BIOLOGY   (United States)

Author keywords

Aging senescence; Differentiation; Epidermal stem cells; P53; Sebaceous gland

Indexed keywords

B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; FAT; MAMMALIAN TARGET OF RAPAMYCIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA ANTAGONIST; PROTEIN P53; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; PRDM1 PROTEIN, MOUSE; REACTIVE OXYGEN METABOLITE; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTION FACTOR;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CUTANEOUS PARAMETERS; ENERGY EXPENDITURE; GENE EXPRESSION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SEBACEOUS GLAND; SENESCENCE; ANIMAL; APOPTOSIS; CELL AGING; CELL DIFFERENTIATION; CYTOLOGY; DEFICIENCY; METABOLISM; STEM CELL; SUBCUTANEOUS TISSUE;

ANIMALS; APOPTOSIS; CELL AGING; CELL DIFFERENTIATION; MICE; MULTIPROTEIN COMPLEXES; PPAR GAMMA; REACTIVE OXYGEN SPECIES; SEBACEOUS GLANDS; SKIN AGING; STEM CELLS; SUBCUTANEOUS TISSUE; TOR SERINE-THREONINE KINASES; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84897450464     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.87     Document Type: Article

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