-
1
-
-
84897128298
-
The noncoding RNA revolution-trashing old rules to forge new ones
-
Cech TR, Steitz JA. The noncoding RNA revolution-trashing old rules to forge new ones. Cell 2014; 157: 77-94.
-
(2014)
Cell
, vol.157
, pp. 77-94
-
-
Cech, T.R.1
Steitz, J.A.2
-
2
-
-
84858379476
-
MicroRNAs in stress signaling and human disease
-
Mendell JT, Olson EN. MicroRNAs in stress signaling and human disease. Cell 2012; 148: 1172-1187.
-
(2012)
Cell
, vol.148
, pp. 1172-1187
-
-
Mendell, J.T.1
Olson, E.N.2
-
3
-
-
4143142117
-
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias
-
Calin GA, Liu CG, Sevignani C, Ferracin M, Felli N, Dumitru CD et al. MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc Natl Acad Sci USA 2004; 101: 11755-11760.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 11755-11760
-
-
Calin, G.A.1
Liu, C.G.2
Sevignani, C.3
Ferracin, M.4
Felli, N.5
Dumitru, C.D.6
-
4
-
-
81755171451
-
MiR-200a regulates Nrf2 activation by targeting Keap1 mRNA in breast cancer cells
-
Eades G, Yang M, Yao Y, Zhang Y, Zhou Q. miR-200a regulates Nrf2 activation by targeting Keap1 mRNA in breast cancer cells. J Biol Chem 286: 40725-40733.
-
J Biol Chem
, vol.286
, pp. 40725-40733
-
-
Eades, G.1
Yang, M.2
Yao, Y.3
Zhang, Y.4
Zhou, Q.5
-
5
-
-
67650365554
-
Restoration of tumour suppressor hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor receptor mutation
-
Cho WC, Chow AS, Au JS. Restoration of tumour suppressor hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor receptor mutation. Eur J Cancer 2009; 45: 2197-2206.
-
(2009)
Eur J Cancer
, vol.45
, pp. 2197-2206
-
-
Cho, W.C.1
Chow, A.S.2
Au, J.S.3
-
6
-
-
84873294160
-
MicroRNA-10a is involved in the metastatic process by regulating Eph tyrosine kinase receptor A4-mediated epithelialmesenchymal transition and adhesion in hepatoma cells
-
Yan Y, Luo YC, Wan HY, Wang J, Zhang PP, Liu M et al. MicroRNA-10a is involved in the metastatic process by regulating Eph tyrosine kinase receptor A4-mediated epithelialmesenchymal transition and adhesion in hepatoma cells. Hepatology 57: 667-677.
-
Hepatology
, vol.57
, pp. 667-677
-
-
Yan, Y.1
Luo, Y.C.2
Wan, H.Y.3
Wang, J.4
Zhang, P.P.5
Liu, M.6
-
7
-
-
84862567064
-
MicroRNA-181b targets cAMP responsive element binding protein 1 in gastric adenocarcinomas
-
Chen L, Yang Q, Kong WQ, Liu T, Liu M, Li X et al. MicroRNA-181b targets cAMP responsive element binding protein 1 in gastric adenocarcinomas. IUBMB Life 64: 628-635.
-
IUBMB Life
, vol.64
, pp. 628-635
-
-
Chen, L.1
Yang, Q.2
Kong, W.Q.3
Liu, T.4
Liu, M.5
Li, X.6
-
8
-
-
22444437609
-
Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
-
Zhao Y, Samal E, Srivastava D. Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature 2005; 436: 214-220.
-
(2005)
Nature
, vol.436
, pp. 214-220
-
-
Zhao, Y.1
Samal, E.2
Srivastava, D.3
-
9
-
-
55849123946
-
MicroRNA-155 is regulated by the transforming growth factor β/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA
-
Kong W, Yang H, He L, Zhao J-j, Coppola D, Dalton WS et al. MicroRNA-155 is regulated by the transforming growth factor β/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA. Mol Cell Biol 2008; 28: 6773-6784.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6773-6784
-
-
Kong, W.1
Yang, H.2
He, L.3
J-J, Z.4
Coppola, D.5
Dalton, W.S.6
-
10
-
-
77956819785
-
Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia
-
Merkel O, Asslaber D, Pinon J, Egle A, Greil R. Interdependent regulation of p53 and miR-34a in chronic lymphocytic leukemia. Cell Cycle 2010; 9: 2836-2840.
-
(2010)
Cell Cycle
, vol.9
, pp. 2836-2840
-
-
Merkel, O.1
Asslaber, D.2
Pinon, J.3
Egle, A.4
Greil, R.5
-
12
-
-
0036141392
-
Regulation of p53 activity by its interaction with homeodomain- interacting protein kinase-2
-
Hofmann TG, Möller A, Sirma H, Zentgraf H, Taya Y, Dröge W et al. Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2. Nat Cell Biol 2001; 4: 1-10.
-
(2001)
Nat Cell Biol
, vol.4
, pp. 1-10
-
-
Hofmann, T.G.1
Möller, A.2
Sirma, H.3
Zentgraf, H.4
Taya, Y.5
Dröge, W.6
-
13
-
-
0034617261
-
Histone deacetylases specifically down-regulate p53-dependent gene activation
-
Juan L-J, Shia W-J, Chen M-H, Yang W-M, Seto E, Lin Y-S et al. Histone deacetylases specifically down-regulate p53-dependent gene activation. J Biol Chem 2000; 275: 20436-20443.
-
(2000)
J Biol Chem
, vol.275
, pp. 20436-20443
-
-
Juan, L.-J.1
Shia, W.-J.2
Chen, M.-H.3
Yang, W.-M.4
Seto, E.5
Lin, Y.-S.6
-
14
-
-
18344377030
-
The p53 pathway: Positive and negative feedback loops
-
Harris SL, Levine AJ. The p53 pathway: positive and negative feedback loops. Oncogene 2005; 24: 2899-2908.
-
(2005)
Oncogene
, vol.24
, pp. 2899-2908
-
-
Harris, S.L.1
Levine, A.J.2
-
15
-
-
0029590161
-
Mdm2 transformation in the absence of p53 and abrogation of the p107 G1 cell-cycle arrest
-
Dubs-Poterszman MC, Tocque B, Wasylyk B. Mdm2 transformation in the absence of p53 and abrogation of the p107 G1 cell-cycle arrest. Oncogene 1995; 11: 2445-2449.
-
(1995)
Oncogene
, vol.11
, pp. 2445-2449
-
-
Dubs-Poterszman, M.C.1
Tocque, B.2
Wasylyk, B.3
-
16
-
-
0035794143
-
Stabilization of the Mdm2 oncoprotein by mutant p53
-
Peng Y, Chen L, Li C, Lu W, Agrawal S, Chen J. Stabilization of the Mdm2 oncoprotein by mutant p53. J Biol Chem 2001; 276: 6874-6878.
-
(2001)
J Biol Chem
, vol.276
, pp. 6874-6878
-
-
Peng, Y.1
Chen, L.2
Li, C.3
Lu, W.4
Agrawal, S.5
Chen, J.6
-
17
-
-
84869093164
-
Functional analysis and consequences of Mdm2 E3 ligase inhibition in human tumor cells
-
Wade M, Li YC, Matani AS, Braun SM, Milanesi F, Rodewald LW et al. Functional analysis and consequences of Mdm2 E3 ligase inhibition in human tumor cells. Oncogene 31: 4789-4797.
-
Oncogene
, vol.31
, pp. 4789-4797
-
-
Wade, M.1
Li, Y.C.2
Matani, A.S.3
Braun, S.M.4
Milanesi, F.5
Rodewald, L.W.6
-
18
-
-
14644437751
-
Mdm2 is a central node in the p53 pathway: 12 years and counting
-
Bond GL, Hu W, Levine AJ. Mdm2 is a central node in the p53 pathway: 12 years and counting. Curr Cancer Drug Targets 2005; 5: 3-8.
-
(2005)
Curr Cancer Drug Targets
, vol.5
, pp. 3-8
-
-
Bond, G.L.1
Hu, W.2
Levine, A.J.3
-
19
-
-
84875596803
-
The role of miR-18b in Mdm2-p53 pathway signaling and melanoma progression
-
Dar AA, Majid S, Rittsteuer C, de Semir D, Bezrookove V, Tong S et al. The role of miR-18b in Mdm2-p53 pathway signaling and melanoma progression. J Natl Cancer Inst 105: 433-442.
-
J Natl Cancer Inst
, vol.105
, pp. 433-442
-
-
Dar, A.A.1
Majid, S.2
Rittsteuer, C.3
De Semir, D.4
Bezrookove, V.5
Tong, S.6
-
20
-
-
77957942585
-
Epigenetics and microRNAs combine to modulate the Mdm2/p53 axis in myeloma
-
Chesi M, Bergsagel PL. Epigenetics and microRNAs combine to modulate the Mdm2/p53 axis in myeloma. Cancer Cell 18: 299-300.
-
Cancer Cell
, vol.18
, pp. 299-300
-
-
Chesi, M.1
Bergsagel, P.L.2
-
21
-
-
83455162789
-
MiR-605 joins p53 network to form a p53:miR-605:Mdm2 positive feedback loop in response to stress
-
Xiao J, Lin H, Luo X, Luo X, Wang Z. miR-605 joins p53 network to form a p53:miR-605:Mdm2 positive feedback loop in response to stress. EMBO J 30: 5021.
-
EMBO J
, vol.30
, pp. 5021
-
-
Xiao, J.1
Lin, H.2
Luo, X.3
Luo, X.4
Wang, Z.5
-
22
-
-
79952277220
-
Mdm2 antagonist nutlin plus proteasome inhibitor velcade combination displays a synergistic anti-myeloma activity
-
Saha MN, Jiang H, Jayakar J, Reece D, Branch DR, Chang H. Mdm2 antagonist nutlin plus proteasome inhibitor velcade combination displays a synergistic anti-myeloma activity. Cancer Biol Ther 9: 936-944.
-
Cancer Biol Ther
, vol.9
, pp. 936-944
-
-
Saha, M.N.1
Jiang, H.2
Jayakar, J.3
Reece, D.4
Branch, D.R.5
Chang, H.6
-
24
-
-
79955715540
-
MicroRNAs (miRNAs) in cancer invasion and metastasis: Therapeutic approaches based on metastasis-related miRNAs
-
Aigner A. MicroRNAs (miRNAs) in cancer invasion and metastasis: therapeutic approaches based on metastasis-related miRNAs. J Mol Med (Berl) 89: 445-457.
-
J Mol Med (Berl)
, vol.89
, pp. 445-457
-
-
Aigner, A.1
-
25
-
-
33750370444
-
MicroRNA signatures in human cancers
-
Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006; 6: 857-866.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
26
-
-
70349750269
-
Investigating the targets of MIR-15a and MIR-16-1 in patients with chronic lymphocytic leukemia (CLL)
-
Hanlon K, Rudin CE, Harries LW. Investigating the targets of MIR-15a and MIR-16-1 in patients with chronic lymphocytic leukemia (CLL). PLoS One 2009; 4: e7169.
-
(2009)
PLoS One
, vol.4
-
-
Hanlon, K.1
Rudin, C.E.2
Harries, L.W.3
-
27
-
-
61349141809
-
Clinicopathological significance of microRNA-31, -143 and -145 expression in colorectal cancer
-
Wang CJ, Zhou ZG, Wang L, Yang L, Zhou B, Gu J et al. Clinicopathological significance of microRNA-31, -143 and -145 expression in colorectal cancer. Dis Markers 2009; 26: 27-34.
-
(2009)
Dis Markers
, vol.26
, pp. 27-34
-
-
Wang, C.J.1
Zhou, Z.G.2
Wang, L.3
Yang, L.4
Zhou, B.5
Gu, J.6
-
28
-
-
77955457044
-
MicroRNAs in mouse models of lymphoid malignancies
-
Zanesi N, Pekarsky Y, Trapasso F, Calin G, Croce CM. MicroRNAs in mouse models of lymphoid malignancies. J Nucleic Acids Investig 1: 36-40.
-
J Nucleic Acids Investig
, vol.1
, pp. 36-40
-
-
Zanesi, N.1
Pekarsky, Y.2
Trapasso, F.3
Calin, G.4
Croce, C.M.5
-
29
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
Calin GA, Sevignani C, Dumitru CD, Hyslop T, Noch E, Yendamuri S et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA 2004; 101: 2999-3004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2999-3004
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
Hyslop, T.4
Noch, E.5
Yendamuri, S.6
-
31
-
-
77957917520
-
Sp1 acetylation is associated with loss of DNA binding at promoters associated with cell cycle arrest and cell death in a colon cell line
-
Waby JS, Chirakkal H, Yu C, Griffiths GJ, Benson RS, Bingle CD et al. Sp1 acetylation is associated with loss of DNA binding at promoters associated with cell cycle arrest and cell death in a colon cell line. Mol Cancer 9: 275.
-
Mol Cancer
, vol.9
, pp. 275
-
-
Waby, J.S.1
Chirakkal, H.2
Yu, C.3
Griffiths, G.J.4
Benson, R.S.5
Bingle, C.D.6
-
32
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y et al. A microRNA component of the p53 tumour suppressor network. Nature 2007; 447: 1130-1134.
-
(2007)
Nature
, vol.447
, pp. 1130-1134
-
-
He, L.1
He, X.2
Lim, L.P.3
De Stanchina, E.4
Xuan, Z.5
Liang, Y.6
-
33
-
-
44249125318
-
Advances in study of murine double minute 2/p53 passway with breast cancer
-
Ba YH, Li HP. Advances in study of murine double minute 2/p53 passway with breast cancer. Beijing Da Xue Xue Bao 2006; 38: 551-554.
-
(2006)
Beijing da Xue Xue Bao
, vol.38
, pp. 551-554
-
-
Ba, Y.H.1
Li, H.P.2
-
34
-
-
3142679581
-
PTEN regulates Mdm2 expression through the P1 promoter
-
Chang C-J, Freeman DJ, Wu H. PTEN regulates Mdm2 expression through the P1 promoter. J Biol Chem 2004; 279: 29841-29848.
-
(2004)
J Biol Chem
, vol.279
, pp. 29841-29848
-
-
Chang, C.-J.1
Freeman, D.J.2
Wu, H.3
-
35
-
-
0037013230
-
Insulin-like growth factor I induces Mdm2-dependent degradation of p53 via the p38 MAPK pathway in response to DNA damage
-
Héron-Milhavet L, LeRoith D. Insulin-like growth factor I induces Mdm2-dependent degradation of p53 via the p38 MAPK pathway in response to DNA damage. J Biol Chem 2002; 277: 15600-15606.
-
(2002)
J Biol Chem
, vol.277
, pp. 15600-15606
-
-
Héron-Milhavet, L.1
Leroith, D.2
-
36
-
-
79551610902
-
MiR-605 joins p53 network to form a p53: MiR-605: Mdm2 positive feedback loop in response to stress
-
Xiao J, Lin H, Luo X, Luo X, Wang Z. miR-605 joins p53 network to form a p53: miR-605: Mdm2 positive feedback loop in response to stress. EMBO J 2011; 30: 524-532.
-
(2011)
EMBO J
, vol.30
, pp. 524-532
-
-
Xiao, J.1
Lin, H.2
Luo, X.3
Luo, X.4
Wang, Z.5
-
37
-
-
33846699083
-
A hexanucleotide element directs microRNA nuclear import
-
Hwang HW, Wentzel EA, Mendell JT 2007A hexanucleotide element directs microRNA nuclear import. Science 315: 97-100.
-
(2007)
Science
, vol.315
, pp. 97-100
-
-
Hwang, H.W.1
Wentzel, E.A.2
Mendell, J.T.3
|